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Recombinant factor VIII Fc fusion protein for the prevention and treatment of bleeding in children with severe hemophilia A
Young, G., Mahlangu, J., Kulkarni, R., Nolan, B., Liesner, R., Pasi, J., Barnes, C., Neelakantan, S., Gambino, G., Cristiano, L. M., Pierce, G. F., Allen, G.
Published in Journal of thrombosis and haemostasis (01.06.2015)
Published in Journal of thrombosis and haemostasis (01.06.2015)
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Long-acting recombinant coagulation factor IX albumin fusion protein (rIX-FP) in hemophilia B: results of a phase 3 trial
Santagostino, Elena, Martinowitz, Uri, Lissitchkov, Toshko, Pan-Petesch, Brigitte, Hanabusa, Hideji, Oldenburg, Johannes, Boggio, Lisa, Negrier, Claude, Pabinger, Ingrid, von Depka Prondzinski, Mario, Altisent, Carmen, Castaman, Giancarlo, Yamamoto, Koji, Álvarez-Roman, Maria-Teresa, Voigt, Christine, Blackman, Nicole, Jacobs, Iris
Published in Blood (07.04.2016)
Published in Blood (07.04.2016)
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Phase III trial results with blisibimod, a selective inhibitor of B-cell activating factor, in subjects with systemic lupus erythematosus (SLE): results from a randomised, double-blind, placebo-controlled trial
Merrill, Joan T, Shanahan, William R, Scheinberg, Morton, Kalunian, Kenneth C, Wofsy, David, Martin, Renee S
Published in Annals of the rheumatic diseases (01.06.2018)
Published in Annals of the rheumatic diseases (01.06.2018)
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Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia A
Mahlangu, Johnny, Powell, Jerry S., Ragni, Margaret V., Chowdary, Pratima, Josephson, Neil C., Pabinger, Ingrid, Hanabusa, Hideji, Gupta, Naresh, Kulkarni, Roshni, Fogarty, Patrick, Perry, David, Shapiro, Amy, Pasi, K. John, Apte, Shashikant, Nestorov, Ivan, Jiang, Haiyan, Li, Shuanglian, Neelakantan, Srividya, Cristiano, Lynda M., Goyal, Jaya, Sommer, Jurg M., Dumont, Jennifer A., Dodd, Nigel, Nugent, Karen, Vigliani, Gloria, Luk, Alvin, Brennan, Aoife, Pierce, Glenn F.
Published in Blood (16.01.2014)
Published in Blood (16.01.2014)
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A Plant-Derived Recombinant Human Glucocerebrosidase Enzyme—A Preclinical and Phase I Investigation
Aviezer, David, Brill-Almon, Einat, Shaaltiel, Yoseph, Hashmueli, Sharon, Bartfeld, Daniel, Mizrachi, Sarah, Liberman, Yael, Freeman, Arnold, Zimran, Ari, Galun, Eithan
Published in PloS one (11.03.2009)
Published in PloS one (11.03.2009)
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Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients
Powell, Jerry S., Josephson, Neil C., Quon, Doris, Ragni, Margaret V., Cheng, Gregory, Li, Ella, Jiang, Haiyan, Li, Lian, Dumont, Jennifer A., Goyal, Jaya, Zhang, Xin, Sommer, Jurg, McCue, Justin, Barbetti, Margaret, Luk, Alvin, Pierce, Glenn F.
Published in Blood (29.03.2012)
Published in Blood (29.03.2012)
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Recombinant factor VIII Fc fusion protein: extended‐interval dosing maintains low bleeding rates and correlates with von Willebrand factor levels
Shapiro, A. D., Ragni, M. V., Kulkarni, R., Oldenberg, J., Srivastava, A., Quon, D. V., Pasi, K. J., Hanabusa, H., Pabinger, I., Mahlangu, J., Fogarty, P., Lillicrap, D., Kulke, S., Potts, J., Neelakantan, S., Nestorov, I., Li, S., Dumont, J. A., Jiang, H., Brennan, A., Pierce, G. F.
Published in Journal of thrombosis and haemostasis (01.11.2014)
Published in Journal of thrombosis and haemostasis (01.11.2014)
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A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors
Jimeno, Antonio, Gordon, Michael, Chugh, Rashmi, Messersmith, Wells, Mendelson, David, Dupont, Jakob, Stagg, Robert, Kapoun, Ann M., Xu, Lu, Uttamsingh, Shailaja, Brachmann, Rainer K., Smith, David C.
Published in Clinical cancer research (15.12.2017)
Published in Clinical cancer research (15.12.2017)
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Long-term safety and efficacy of extended-interval prophylaxis with recombinant factor IX Fc fusion protein (rFIXFc) in subjects with haemophilia B
Pasi, K John, Fischer, Kathelijn, Ragni, Margaret, Nolan, Beatrice, Perry, David J, Kulkarni, Roshni, Ozelo, Margareth, Mahlangu, Johnny, Shapiro, Amy D, Baker, Ross I, Bennett, Carolyn M, Barnes, Christopher, Oldenburg, Johannes, Matsushita, Tadashi, Yuan, Huixing, Ramirez-Santiago, Alejandra, Pierce, Glenn F, Allen, Geoffrey, Mei, Baisong
Published in Thrombosis and haemostasis (2017)
Published in Thrombosis and haemostasis (2017)
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Safety, pharmacokinetics, and biomarkers of F-652, a recombinant human interleukin-22 dimer, in healthy subjects
Tang, Kai-Yang, Lickliter, Jason, Huang, Zhi-Hua, Xian, Zong-Shu, Chen, Han-Yang, Huang, Cheng, Xiao, Chong, Wang, Yu-Peng, Tan, Ying, Xu, Lin-Feng, Huang, Yu-Liang, Yan, Xiao-Qiang
Published in Cellular & molecular immunology (01.05.2019)
Published in Cellular & molecular immunology (01.05.2019)
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Long-term safety and efficacy of recombinant factor VIII Fc fusion protein (rFVIIIFc) in subjects with haemophilia A
Nolan, B., Mahlangu, J., Perry, D., Young, G., Liesner, R., Konkle, B., Rangarajan, S., Brown, S., Hanabusa, H., Pasi, K. J., Pabinger, I., Jackson, S., Cristiano, L. M., Li, X., Pierce, G. F., Allen, G.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2016)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2016)
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Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120
Yolitz, Jason, Schwing, Catherine, Chang, Julia, Van Ryk, Donald, Nawaz, Fatima, Wei, Danlan, Cicala, Claudia, Arthos, James, Fauci, Anthony S.
Published in Proceedings of the National Academy of Sciences - PNAS (06.03.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (06.03.2018)
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Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti–IL-5 receptor α antibody, in a phase I study of subjects with mild asthma
Busse, William W., Katial, Rohit, Gossage, David, Sari, Suha, Wang, Bing, Kolbeck, Roland, Coyle, Anthony J., Koike, Masamichi, Spitalny, George L., Kiener, Peter A., Geba, Gregory P., Molfino, Nestor A.
Published in Journal of allergy and clinical immunology (01.06.2010)
Published in Journal of allergy and clinical immunology (01.06.2010)
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First-in-Human Phase I Trial of a Tumor-Targeted Cytokine (NHS-IL12) in Subjects with Metastatic Solid Tumors
Strauss, Julius, Heery, Christopher R., Kim, Joseph W., Jochems, Caroline, Donahue, Renee N., Montgomery, Agnes S., McMahon, Sheri, Lamping, Elizabeth, Marté, Jennifer L., Madan, Ravi A., Bilusic, Marijo, Silver, Matthew R., Bertotti, Elisa, Schlom, Jeffrey, Gulley, James L.
Published in Clinical cancer research (01.01.2019)
Published in Clinical cancer research (01.01.2019)
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Effects of Tirzepatide, a Dual GIP and GLP-1 RA, on Lipid and Metabolite Profiles in Subjects With Type 2 Diabetes
Pirro, Valentina, Roth, Kenneth D, Lin, Yanzhu, Willency, Jill A, Milligan, Paul L, Wilson, Jonathan M, Ruotolo, Giacomo, Haupt, Axel, Newgard, Christopher B, Duffin, Kevin L
Published in The journal of clinical endocrinology and metabolism (01.02.2022)
Published in The journal of clinical endocrinology and metabolism (01.02.2022)
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T cells expressing chimeric antigen receptors can cause anaphylaxis in humans
Maus, Marcela V, Haas, Andrew R, Beatty, Gregory L, Albelda, Steven M, Levine, Bruce L, Liu, Xiaojun, Zhao, Yangbing, Kalos, Michael, June, Carl H
Published in Cancer immunology research (01.07.2013)
Published in Cancer immunology research (01.07.2013)
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A novel liposomal adjuvant system, CAF01, promotes long-lived Mycobacterium tuberculosis-specific T-cell responses in human
van Dissel, Jaap T., Joosten, Simone A., Hoff, Søren T., Soonawala, Darius, Prins, Corine, Hokey, David A., O’Dee, Dawn M., Graves, Andrew, Thierry-Carstensen, Birgit, Andreasen, Lars V., Ruhwald, Morten, de Visser, Adriëtte W., Agger, Else Marie, Ottenhoff, Tom H.M., Kromann, Ingrid, Andersen, Peter
Published in Vaccine (12.12.2014)
Published in Vaccine (12.12.2014)
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Design of multi-epitope peptides containing HLA class-I and class-II-restricted epitopes derived from immunogenic Leishmania proteins, and evaluation of CD4+ and CD8+ T cell responses induced in cured cutaneous leishmaniasis subjects
Hamrouni, Sarra, Bras-Gonçalves, Rachel, Kidar, Abdelhamid, Aoun, Karim, Chamakh-Ayari, Rym, Petitdidier, Elodie, Messaoudi, Yasmine, Pagniez, Julie, Lemesre, Jean-Loup, Meddeb-Garnaoui, Amel
Published in PLoS neglected tropical diseases (01.03.2020)
Published in PLoS neglected tropical diseases (01.03.2020)
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A randomized, two-armed, double-blind, single-dose, cross-over, bioequivalence clinical trial to compare pharmacokinetic parameters and safety of recombinant human factor VIII with Fc fusion produced by AryoGen Pharmed Company versus Elocta® (reference product) in previously treated patients with severe haemophilia A
Eghbali, Aziz, Eshghi, Peyman, Toogeh, Gholamreza, Alavi, Samin, Badiei, Zahra, Ghanavat, Majid, Bordbar, Mohammadreza, Bazrafshan, Asghar, Karimi, Katayoon, Ahmadinejad, Minoo, Sabzvari, Araz, Kafi, Hamidreza
Published in Annals of hematology (01.02.2025)
Published in Annals of hematology (01.02.2025)
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