Loading…
Long‐acting recombinant factor IX Fc fusion protein (rFIXFc) for perioperative management of subjects with haemophilia B in the phase 3 B‐LONG study
Powell, Jerry S., Apte, Shashikant, Chambost, Hervé, Hermans, Cedric, Jackson, Shannon, Josephson, Neil C., Mahlangu, Johnny N., Ozelo, Margareth C., Peerlinck, Kathelijne, Pasi, John, Perry, David, Ragni, Margaret V., Wang, Xuefeng, Jiang, Haiyan, Li, Shuanglian, Cristiano, Lynda M., Innes, Alison, Nugent, Karen, Brennan, Aoife, Luk, Alvin, Allen, Geoffrey, Pierce, Glenn F., Robinson, Brian
Published in British journal of haematology (01.01.2015)
Published in British journal of haematology (01.01.2015)
Get full text
Journal Article
Loading…
Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients
Shapiro, Amy D., Ragni, Margaret V., Valentino, Leonard A., Key, Nigel S., Josephson, Neil C., Powell, Jerry S., Cheng, Gregory, Thompson, Arthur R., Goyal, Jaya, Tubridy, Karen L., Peters, Robert T., Dumont, Jennifer A., Euwart, Donald, Li, Lian, Hallén, Bengt, Gozzi, Peter, Bitonti, Alan J., Jiang, Haiyan, Luk, Alvin, Pierce, Glenn F.
Published in Blood (19.01.2012)
Published in Blood (19.01.2012)
Get full text
Journal Article
Loading…
Long-term safety and efficacy of extended-interval prophylaxis with recombinant factor IX Fc fusion protein (rFIXFc) in subjects with haemophilia B
Pasi, K John, Fischer, Kathelijn, Ragni, Margaret, Nolan, Beatrice, Perry, David J, Kulkarni, Roshni, Ozelo, Margareth, Mahlangu, Johnny, Shapiro, Amy D, Baker, Ross I, Bennett, Carolyn M, Barnes, Christopher, Oldenburg, Johannes, Matsushita, Tadashi, Yuan, Huixing, Ramirez-Santiago, Alejandra, Pierce, Glenn F, Allen, Geoffrey, Mei, Baisong
Published in Thrombosis and haemostasis (2017)
Published in Thrombosis and haemostasis (2017)
Get more information
Journal Article
Loading…
Real-World Data on the Use of rFIXFc in Subjects With Hemophilia B for Up to 3.7 Years Demonstrates Improved Bleed Control and Adherence With Reduced Treatment Burden
Shapiro, Amy, Chaudhury, Ateefa, Jain, Nisha, Tsao, Elisa, Barnowski, Chris, Feng, Jing, Quon, Doris
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
Get full text
Journal Article
Loading…
B-YOND Final Results Confirm Established Safety, Sustained Efficacy, and Extended Dosing Interval for Up to 4 Years of Treatment With rFIXFc in Previously Treated Subjects With Severe Hemophilia B
Ragni, Margaret, Kulkarni, Roshni, Pasi, K. John, Fischer, Kathelijn, Mahlangu, Johnny, Shapiro, Amy, Nolan, Beatrice, Oldenburg, Johannes, Matsushita, Tadashi, Willemze, Annemieke, Yuan, Huixing, Rudin, Dan
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
Get full text
Journal Article
Loading…
Prophylaxis with rFIXFc Reduces the Frequency and Delays Time to First Spontaneous Bleed Event in Previously Untreated Patients with Hemophilia B: A Post Hoc Analysis of the PUPs B-LONG Trial
Nolan, Beatrice, Recht, Michael, Rendo, Pablo, Falk, Aletta, Foster, Meredith, Casiano, Sandra, Rauch, Antoine, Shapiro, Amy D.
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
Get full text
Journal Article
Loading…
Clinical Outcomes of 14-Day Prophylaxis with rFIXFc: Longitudinal Analysis of the B-LONG and B-YOND Study
Shapiro, Amy D., Ozelo, Margareth C, Pasi, K John, Feng, Jingyuan, Winding, Bent, Barnowski, Chris, Kulkarni, Roshni
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
Get full text
Journal Article
Loading…
Long Term Safety and Efficacy of Recombinant Factor IX Fc Fusion Protein (rFIXFc) Prophylaxis in Children with Hemophilia B: Interim Results of the B-Yond Extension Study
Ducore, Jonathan M., Fischer, Kathelijn, Kulkarni, Roshni, Nolan, Beatrice, Bennett, Carolyn M., Perry, David J, Yuan, Huixing, Ramirez-Santiago, Alejandra, Ferrante, Francesca, Lethagen, Stefan
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
Get full text
Journal Article
Loading…
Clinical Outcomes in Adults/Adolescents with Hemophilia B Treated Long Term with Recombinant Factor IX Fc Fusion Protein (rFIXFc) Prophylaxis: Interim Results of the B-Yond Extension Study
Matsushita, Tadashi, Mahlangu, Johnny, Shapiro, Amy D, Pasi, K John, Ragni, Margaret V., Ozelo, Margareth C, Oldenburg, Johannes, Baker, Ross I, Yuan, Huixing, Ramirez-Santiago, Alejandra, Ferrante, Francesca, Lethagen, Stefan
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
Get full text
Journal Article
Loading…
Clinical Outcomes in Children with Hemophilia B Treated Long Term with rFIXFc: Interim Results of the B-YOND Extension Study
Kulkarni, Roshni, Nolan, Beatrice, Bennett, Carolyn M., Fischer, Kathelijn, Perry, David J, Barnes, Christopher, Yuan, Huixing, Ramirez-Santiago, Alejandra, Pierce, Glenn F, Mei, Baisong
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
Get full text
Journal Article
Loading…
Extended-Interval Prophylaxis with rFIXFc in Adults and Adolescents with Hemophilia B: Interim Results of the B-YOND Extension Study
Mahlangu, Johnny, Shapiro, Amy D, Pasi, K John, Ragni, Margaret V, Ozelo, Margareth Castro, Oldenburg, Johannes, Matsushita, Tadashi, Baker, Ross I, Yuan, Huixing, Ramirez-Santiago, Alejandra, Pierce, Glenn F, Allen, Geoffrey, Mei, Baisong
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
Get full text
Journal Article
Loading…
Pharmacokinetics Of Recombinant Factor IX Fc Fusion Protein (rFIXFc) In Pediatric Subjects With Hemophilia B: An Interim Analysis Of The Kids B-LONG Study
Fischer, Kathelijn, Kulkarni, Roshni, Bradbury, Myles, Ragni, Margaret V., Rangarajan, Savita, Dong, Yingwen, Li, Shuanglian, Jiang, Haiyan, Nugent, Karen, Pierce, Glenn F, Allen, Geoffrey
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
Get full text
Journal Article
Loading…
Pharmacokinetics, Safety, and Efficacy Of Long-Lasting Recombinant Factor IX Fc Fusion Protein (rFIXFc) In Adolescent Subjects With Hemophilia B: A Subgroup Analysis Of The B-LONG Study
Shapiro, Amy, Pasi, John, Mahlangu, Johnny, Perry, David J., Powell, Jerry S, Ragni, Margaret V., Valentino, Leonard A., Ozelo, Margareth, Nugent, Karen, Li, Shuanglian, Brennan, Aoife, Pierce, Glenn F, Allen, Geoffrey
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
Get full text
Journal Article
Loading…
Low Bleeding Rates with Increase or Maintenance of Physical Activity in Patients Treated with Recombinant Factor IX Fc Fusion Protein (rFIXFc) in the B-LONG and Kids B-LONG Studies
Kulkarni, Roshni, Shapiro, Amy D, Windyga, Jerzy, Ragni, Margaret V, Pasi, K John, Ozelo, Margareth Castro, Tsao, Elisa, Mei, Baisong
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
Get full text
Journal Article
Loading…
B-YOND Final Results Confirm Established Safety, Sustained Efficacy, and Extended Dosing Interval for Up to 4 Years of Treatment With rFIXFc in Previously Treated Subjects With Severe Hemophilia B
Johannes Oldenburg, Roshni Kulkarni, Amy D. Shapiro, K. John Pasi, Johnny Mahlangu, Huixing Yuan, Annemieke Willemze, Tadashi Matsushita, Margaret V. Ragni, Beatrice Nolan, Dan Rudin, Krista Fischer
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
Get full text
Journal Article
Loading…
Long‐term safety and sustained efficacy for up to 5 years of treatment with recombinant factor IX Fc fusion protein in subjects with haemophilia B: Results from the B‐YOND extension study
Pasi, K. John, Fischer, Kathelijn, Ragni, Margaret, Kulkarni, Roshni, Ozelo, Margareth C., Mahlangu, Johnny, Shapiro, Amy, P’Ng, Stephanie, Chambost, Hervé, Nolan, Beatrice, Bennett, Carolyn, Matsushita, Tadashi, Winding, Bent, Fruebis, Joachim, Yuan, Huixing, Rudin, Dan, Oldenburg, Johannes
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2020)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2020)
Get full text
Journal Article
Loading…
Clinical Outcomes in Adults/Adolescents with Hemophilia B Treated Long Term with Recombinant Factor IX Fc Fusion Protein (rFIXFc) Prophylaxis: Interim Results of the B-Yond Extension Study
Alejandra Ramirez-Santiago, Amy D. Shapiro, Margareth C. Ozelo, K. John Pasi, Ross I. Baker, Margaret V. Ragni, Huixing Yuan, Johannes Oldenburg, Stefan Lethagen, Johnny Mahlangu, Francesca Ferrante, Tadashi Matsushita
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
Get full text
Journal Article
Loading…
Extended-Interval Prophylaxis with rFIXFc in Adults and Adolescents with Hemophilia B: Interim Results of the B-YOND Extension Study
K. John Pasi, Margaret V. Ragni, Baisong Mei, Ross I. Baker, Margareth C. Ozelo, G. Allen, Alejandra Ramirez-Santiago, Johannes Oldenburg, Glenn F. Pierce, Johnny Mahlangu, Amy D. Shapiro, Tadashi Matsushita, Huixing Yuan
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
Get full text
Journal Article
Loading…
Switching to recombinant factor IX Fc fusion protein prophylaxis results in fewer infusions, decreased factor IX consumption and lower bleeding rates
Powell, Jerry, Shapiro, Amy, Ragni, Margaret, Negrier, Claude, Windyga, Jerzy, Ozelo, Margareth, Pasi, John, Baker, Ross, Potts, James, Li, Shuanglian, Mei, Baisong, Pierce, Glenn F., Robinson, Brian
Published in British journal of haematology (01.01.2015)
Published in British journal of haematology (01.01.2015)
Get full text
Journal Article
Loading…
Prophylaxis with recombinant factor IX Fc fusion protein reduces the risk of bleeding and delays time to first spontaneous bleed event in previously untreated patients with haemophilia B: A post hoc analysis of the PUPs B‐LONG study
Nolan, Beatrice, Recht, Michael, Rendo, Pablo, Falk, Aletta, Foster, Meredith, Casiano, Sandra, Rauch, Antoine, Shapiro, Amy
Published in European journal of haematology (01.10.2024)
Published in European journal of haematology (01.10.2024)
Get full text
Journal Article