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Genetics of rheumatoid arthritis contributes to biology and drug discovery
Okada, Yukinori, Wu, Di, Trynka, Gosia, Raj, Towfique, Terao, Chikashi, Ikari, Katsunori, Kochi, Yuta, Ohmura, Koichiro, Suzuki, Akari, Yoshida, Shinji, Graham, Robert R., Manoharan, Arun, Ortmann, Ward, Bhangale, Tushar, Denny, Joshua C., Carroll, Robert J., Eyler, Anne E., Greenberg, Jeffrey D., Kremer, Joel M., Pappas, Dimitrios A., Jiang, Lei, Yin, Jian, Ye, Lingying, Su, Ding-Feng, Yang, Jian, Xie, Gang, Keystone, Ed, Westra, Harm-Jan, Esko, Tõnu, Metspalu, Andres, Zhou, Xuezhong, Gupta, Namrata, Mirel, Daniel, Stahl, Eli A., Diogo, Dorothée, Cui, Jing, Liao, Katherine, Guo, Michael H., Myouzen, Keiko, Kawaguchi, Takahisa, Coenen, Marieke J. H., van Riel, Piet L. C. M., van de Laar, Mart A. F. J., Guchelaar, Henk-Jan, Huizinga, Tom W. J., Dieudé, Philippe, Mariette, Xavier, Louis Bridges Jr, S., Zhernakova, Alexandra, Toes, Rene E. M., Tak, Paul P., Miceli-Richard, Corinne, Bang, So-Young, Lee, Hye-Soon, Martin, Javier, Gonzalez-Gay, Miguel A., Rodriguez-Rodriguez, Luis, Rantapää-Dahlqvist, Solbritt, Ärlestig, Lisbeth, Choi, Hyon K., Kamatani, Yoichiro, Galan, Pilar, Lathrop, Mark, Eyre, Steve, Bowes, John, Barton, Anne, de Vries, Niek, Moreland, Larry W., Criswell, Lindsey A., Karlson, Elizabeth W., Taniguchi, Atsuo, Yamada, Ryo, Kubo, Michiaki, Liu, Jun S., Bae, Sang-Cheol, Worthington, Jane, Padyukov, Leonid, Klareskog, Lars, Gregersen, Peter K., Raychaudhuri, Soumya, Stranger, Barbara E., De Jager, Philip L., Franke, Lude, Visscher, Peter M., Brown, Matthew A., Yamanaka, Hisashi, Mimori, Tsuneyo, Takahashi, Atsushi, Xu, Huji, Behrens, Timothy W., Siminovitch, Katherine A., Momohara, Shigeki, Matsuda, Fumihiko, Yamamoto, Kazuhiko, Plenge, Robert M.
Published in Nature (London) (20.02.2014)
Published in Nature (London) (20.02.2014)
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Heritability and genomics of gene expression in peripheral blood
Wright, Fred A, Sullivan, Patrick F, Brooks, Andrew I, Zou, Fei, Sun, Wei, Xia, Kai, Madar, Vered, Jansen, Rick, Chung, Wonil, Zhou, Yi-Hui, Abdellaoui, Abdel, Batista, Sandra, Butler, Casey, Chen, Guanhua, Chen, Ting-Huei, D'Ambrosio, David, Gallins, Paul, Ha, Min Jin, Hottenga, Jouke Jan, Huang, Shunping, Kattenberg, Mathijs, Kochar, Jaspreet, Middeldorp, Christel M, Qu, Ani, Shabalin, Andrey, Tischfield, Jay, Todd, Laura, Tzeng, Jung-Ying, van Grootheest, Gerard, Vink, Jacqueline M, Wang, Qi, Wang, Wei, Wang, Weibo, Willemsen, Gonneke, Smit, Johannes H, de Geus, Eco J, Yin, Zhaoyu, Penninx, Brenda W J H, Boomsma, Dorret I
Published in Nature genetics (01.05.2014)
Published in Nature genetics (01.05.2014)
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A population genetic interpretation of GWAS findings for human quantitative traits
Simons, Yuval B., Bullaughey, Kevin, Hudson, Richard R., Sella, Guy
Published in PLoS biology (16.03.2018)
Published in PLoS biology (16.03.2018)
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Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension
Harbaum, Lars, Rhodes, Christopher J., Wharton, John, Lawrie, Allan, Karnes, Jason H., Desai, Ankit A., Nichols, William C., Humbert, Marc, Montani, David, Girerd, Barbara, Sitbon, Olivier, Boehm, Mario, Novoyatleva, Tatyana, Schermuly, Ralph T., Ghofrani, H. Ardeschir, Toshner, Mark, Kiely, David G., Howard, Luke S., Swietlik, Emilia M., Gräf, Stefan, Pietzner, Maik, Morrell, Nicholas W., Wilkins, Martin R., Southgate, L, Machado, RD, Martin, J, Ouwehand, WH, Pauciulo, MW, Arora, A, Lutz, K, Ahmad, F, Archer, SL, Argula, R, Austin, ED, Badesch, D, Bakshi, S, Barnett, C, Benza, R, Bhatt, N, Burger, CD, Chakinala, M, Elwing, J, Fortin, T, Frantz, RP, Frost, A, Garcia, JGN, Harley, J, He, H, Hill, NS, Hirsch, R, Ivy, D, Klinger, J, Lahm, T, Marsolo, K, Martin, LJ, Nathan, SD, Oudiz, RJ, Rehman, Z, Robbins, I, Roden, DM, Rosenzweig, EB, Saydain, G, Schilz, R, Simms, RW, Simon, M, Tang, H, Tchourbanov, AY, Thenappan, T, Torres, F, Walsworth, AK, Walter, RE, White, RJ, Wilt, J, Yung, D, Kittles, R, Aman, J, Knight, J, Hanscombe, KB, Gall, H, Ulrich, A, Bogaard, HJ, Church, C, Coghlan, JG, Condliffe, R, Corris, PA, Danesino, C, Elliott, CG, Franke, A, Ghio, S, Gibbs, JSR, Houweling, AC, Kovacs, G, Laudes, M, MacKenzie Ross, RV, Moledina, S, Newnham, M, Olschewski, A, Olschewski, H, Peacock, AJ, Pepke-Zaba, J
Published in American journal of respiratory and critical care medicine (15.06.2022)
Published in American journal of respiratory and critical care medicine (15.06.2022)
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Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kimura, Kouichi, Wakamatsu, Ai, Suzuki, Yutaka, Ota, Toshio, Nishikawa, Tetsuo, Yamashita, Riu, Yamamoto, Jun-ichi, Sekine, Mitsuo, Tsuritani, Katsuki, Wakaguri, Hiroyuki, Ishii, Shizuko, Sugiyama, Tomoyasu, Saito, Kaoru, Isono, Yuko, Irie, Ryotaro, Kushida, Norihiro, Yoneyama, Takahiro, Otsuka, Rie, Kanda, Katsuhiro, Yokoi, Takahide, Kondo, Hiroshi, Wagatsuma, Masako, Murakawa, Katsuji, Ishida, Shinichi, Ishibashi, Tadashi, Takahashi-Fujii, Asako, Tanase, Tomoo, Nagai, Keiichi, Kikuchi, Hisashi, Nakai, Kenta, Isogai, Takao, Sugano, Sumio
Published in Genome Research (01.01.2006)
Published in Genome Research (01.01.2006)
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Identifying plant genes shaping microbiota composition in the barley rhizosphere
Escudero-Martinez, Carmen, Coulter, Max, Alegria Terrazas, Rodrigo, Foito, Alexandre, Kapadia, Rumana, Pietrangelo, Laura, Maver, Mauro, Sharma, Rajiv, Aprile, Alessio, Morris, Jenny, Hedley, Pete E., Maurer, Andreas, Pillen, Klaus, Naclerio, Gino, Mimmo, Tanja, Barton, Geoffrey J., Waugh, Robbie, Abbott, James, Bulgarelli, Davide
Published in Nature communications (16.06.2022)
Published in Nature communications (16.06.2022)
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Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus
Morris, David L, Sheng, Yujun, Zhang, Yan, Wang, Yong-Fei, Zhu, Zhengwei, Tombleson, Philip, Chen, Lingyan, Cunninghame Graham, Deborah S, Bentham, James, Roberts, Amy L, Chen, Ruoyan, Zuo, Xianbo, Wang, Tingyou, Wen, Leilei, Yang, Chao, Liu, Lu, Yang, Lulu, Li, Feng, Huang, Yuanbo, Yin, Xianyong, Yang, Sen, Rönnblom, Lars, Fürnrohr, Barbara G, Voll, Reinhard E, Schett, Georg, Costedoat–Chalumeau, Nathalie, Gaffney, Patrick M, Lau, Yu Lung, Zhang, Xuejun, Yang, Wanling, Cui, Yong, Vyse, Timothy J
Published in Nature genetics (01.08.2016)
Published in Nature genetics (01.08.2016)
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Integrating Genome-Wide Genetic Variations and Monocyte Expression Data Reveals Trans-Regulated Gene Modules in Humans
Rotival, Maxime, Zeller, Tanja, Wild, Philipp S., Maouche, Seraya, Szymczak, Silke, Schillert, Arne, Castagné, Raphaele, Deiseroth, Arne, Proust, Carole, Brocheton, Jessy, Godefroy, Tiphaine, Perret, Claire, Germain, Marine, Eleftheriadis, Medea, Sinning, Christoph R., Schnabel, Renate B., Lubos, Edith, Lackner, Karl J., Rossmann, Heidi, Münzel, Thomas, Rendon, Augusto, Consortium, Cardiogenics, Erdmann, Jeanette, Deloukas, Panos, Hengstenberg, Christian, Diemert, Patrick, Montalescot, Gilles, Ouwehand, Willem H., Samani, Nilesh J., Schunkert, Heribert, Tregouet, David-Alexandre, Ziegler, Andreas, Goodall, Alison H., Cambien, François, Tiret, Laurence, Blankenberg, Stefan
Published in PLoS genetics (01.12.2011)
Published in PLoS genetics (01.12.2011)
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Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome
Porcu, Eleonora, Sadler, Marie C., Lepik, Kaido, Auwerx, Chiara, Wood, Andrew R., Weihs, Antoine, Sleiman, Maroun S. Bou, Ribeiro, Diogo M., Bandinelli, Stefania, Tanaka, Toshiko, Nauck, Matthias, Völker, Uwe, Delaneau, Olivier, Metspalu, Andres, Teumer, Alexander, Frayling, Timothy, Santoni, Federico A., Reymond, Alexandre, Kutalik, Zoltán
Published in Nature communications (24.09.2021)
Published in Nature communications (24.09.2021)
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Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx
Gay, Nicole R., Gloudemans, Michael, Antonio, Margaret L., Abell, Nathan S., Balliu, Brunilda, Park, YoSon, Martin, Alicia R., Musharoff, Shaila, Rao, Abhiram S., Aguet, François, Barbeira, Alvaro N., Bonazzola, Rodrigo, Hormozdiari, Farhad, Ardlie, Kristin G., Brown, Christopher D., Im, Hae Kyung, Lappalainen, Tuuli, Wen, Xiaoquan, Montgomery, Stephen B.
Published in Genome Biology (11.09.2020)
Published in Genome Biology (11.09.2020)
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QTG-Seq Accelerates QTL Fine Mapping through QTL Partitioning and Whole-Genome Sequencing of Bulked Segregant Samples
Zhang, Hongwei, Wang, Xi, Pan, Qingchun, Li, Pei, Liu, Yunjun, Lu, Xiaoduo, Zhong, Wanshun, Li, Minqi, Han, Linqian, Li, Juan, Wang, Pingxi, Li, Dongdong, Liu, Yan, Li, Qing, Yang, Fang, Zhang, Yuan-Ming, Wang, Guoying, Li, Lin
Published in Molecular plant (04.03.2019)
Published in Molecular plant (04.03.2019)
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Genetic variants of genes in the NER pathway associated with risk of breast cancer: A large‐scale analysis of 14 published GWAS datasets in the DRIVE study
Ge, Jie, Liu, Hongliang, Qian, Danwen, Wang, Xiaomeng, Moorman, Patricia G., Luo, Sheng, Hwang, Shelley, Wei, Qingyi
Published in International journal of cancer (01.09.2019)
Published in International journal of cancer (01.09.2019)
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Phenotype–Genotype Integrator (PheGenI): synthesizing genome-wide association study (GWAS) data with existing genomic resources
Ramos, Erin M, Hoffman, Douglas, Junkins, Heather A, Maglott, Donna, Phan, Lon, Sherry, Stephen T, Feolo, Mike, Hindorff, Lucia A
Published in European journal of human genetics : EJHG (01.01.2014)
Published in European journal of human genetics : EJHG (01.01.2014)
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Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression
Fairfax, Benjamin P., Humburg, Peter, Makino, Seiko, Naranbhai, Vivek, Wong, Daniel, Lau, Evelyn, Jostins, Luke, Plant, Katharine, Andrews, Robert, McGee, Chris, Knight, Julian C.
Published in Science (American Association for the Advancement of Science) (07.03.2014)
Published in Science (American Association for the Advancement of Science) (07.03.2014)
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Quantifying Wheat Sensitivities to Environmental Constraints to Dissect Genotype × Environment Interactions in the Field
Parent, Boris, Bonneau, Julien, Maphosa, Lance, Kovalchuk, Alex, Langridge, Peter, Fleury, Delphine
Published in Plant physiology (Bethesda) (01.07.2017)
Published in Plant physiology (Bethesda) (01.07.2017)
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