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Effect of lopinavir/ritonavir on the pharmacokinetics of selexipag an oral prostacyclin receptor agonist and its active metabolite in healthy subjects
Kaufmann, Priska, Niglis, Séverine, Bruderer, Shirin, Segrestaa, Jérôme, Äänismaa, Päivi, Halabi, Atef, Dingemanse, Jasper
Published in British journal of clinical pharmacology (01.10.2015)
Published in British journal of clinical pharmacology (01.10.2015)
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Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: results from two randomized, double-blind, placebo-controlled studies with single oral doses
Herman, Gary A, Stevens, Cathy, Van Dyck, Kristien, Bergman, Arthur, Yi, Bingming, De Smet, Marina, Snyder, Karen, Hilliard, Deborah, Tanen, Michael, Tanaka, Wesley, Wang, Amy Q, Zeng, Wei, Musson, Donald, Winchell, Gregory, Davies, Michael J, Ramael, Steven, Gottesdiener, Keith M, Wagner, John A
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A pharmacokinetic drug–drug interaction study between selexipag and midazolam, a CYP3A4 substrate, in healthy male subjects
Juif, Pierre-Eric, Boehler, Margaux, Donazzolo, Yves, Bruderer, Shirin, Dingemanse, Jasper
Published in European journal of clinical pharmacology (01.09.2017)
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An open-label phase 2 trial of entospletinib (GS-9973), a selective spleen tyrosine kinase inhibitor, in chronic lymphocytic leukemia
Sharman, Jeff, Hawkins, Michael, Kolibaba, Kathryn, Boxer, Michael, Klein, Leonard, Wu, Meihua, Hu, Jing, Abella, Steve, Yasenchak, Chris
Published in Blood (09.04.2015)
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Effect of gemfibrozil and rifampicin on the pharmacokinetics of selexipag and its active metabolite in healthy subjects
Bruderer, Shirin, Petersen‐Sylla, Marc, Boehler, Margaux, Remeňová, Tatiana, Halabi, Atef, Dingemanse, Jasper
Published in British journal of clinical pharmacology (01.12.2017)
Published in British journal of clinical pharmacology (01.12.2017)
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Pharmacokinetics and pharmacodynamic effects of the oral DPP-4 inhibitor sitagliptin in middle-aged obese subjects
Herman, Gary A, Bergman, Arthur, Liu, Fang, Stevens, Cathy, Wang, Amy Q, Zeng, Wei, Chen, Li, Snyder, Karen, Hilliard, Deborah, Tanen, Michael, Tanaka, Wesley, Meehan, Alan G, Lasseter, Kenneth, Dilzer, Stacy, Blum, Robert, Wagner, John A
Published in Journal of clinical pharmacology (01.08.2006)
Published in Journal of clinical pharmacology (01.08.2006)
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A first-in-Asian phase 1 study to evaluate safety, pharmacokinetics and clinical activity of VS-6063, a focal adhesion kinase (FAK) inhibitor in Japanese patients with advanced solid tumors
Shimizu, Toshio, Fukuoka, Kazuya, Takeda, Masayuki, Iwasa, Tutomu, Yoshida, Takeshi, Horobin, Joanna, Keegan, Mitchell, Vaickus, Lou, Chavan, Ajit, Padval, Mahesh, Nakagawa, Kazuhiko
Published in Cancer chemotherapy and pharmacology (01.05.2016)
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Multiple-Dose Up-Titration Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Selexipag, an Orally Available Selective Prostacyclin Receptor Agonist, in Healthy Subjects
Bruderer, Shirin, Hurst, Noémie, Kaufmann, Priska, Dingemanse, Jasper
Published in Pharmacology (01.01.2014)
Published in Pharmacology (01.01.2014)
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Pharmacokinetics of the novel oral prostacyclin receptor agonist selexipag in subjects with hepatic or renal impairment
Kaufmann, Priska, Cruz, Hans G., Krause, Andreas, Ulč, Ivan, Halabi, Atef, Dingemanse, Jasper
Published in British journal of clinical pharmacology (01.08.2016)
Published in British journal of clinical pharmacology (01.08.2016)
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Pharmacokinetics and Safety of PTC596, a Novel Tubulin‐Binding Agent, in Subjects With Advanced Solid Tumors
Shapiro, Geoffrey I., O'Mara, Edward, Laskin, Oscar L., Gao, Lan, Baird, John D., Spiegel, Robert J., Kaushik, Diksha, Weetall, Marla, Colacino, Joseph, O'Keefe, Kylie, Branstrom, Arthur, Goodwin, Elizabeth, Infante, Jeffrey, Bedard, Philippe L., Kong, Ronald
Published in Clinical pharmacology in drug development (01.08.2021)
Published in Clinical pharmacology in drug development (01.08.2021)
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Evaluation of drug–drug interactions of a novel potent FLT3 inhibitor SKLB1028 in healthy subjects
Chen, Jingcheng, Wu, Jingxuan, Guo, Nini, Song, Yuqin, Li, Lijun, Wang, Bingyan, Li, Jiangshuo, Hou, Mengyu, Yin, Hang, Zhang, Meijuan, Kong, Yanhong, Wu, Xiaofang, Li, Ran, Wu, Le, Gao, Qiannan, Dong, Ruihua
Published in Clinical and translational science (01.11.2024)
Published in Clinical and translational science (01.11.2024)
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Clinical Outcomes and Plasma Concentrations of Baloxavir Marboxil and Favipiravir in COVID-19 Patients: An Exploratory Randomized, Controlled Trial
Lou, Yan, Liu, Lin, Yao, Hangping, Hu, Xingjiang, Su, Junwei, Xu, Kaijin, Luo, Rui, Yang, Xi, He, Lingjuan, Lu, Xiaoyang, Zhao, Qingwei, Liang, Tingbo, Qiu, Yunqing
Published in European journal of pharmaceutical sciences (01.02.2021)
Published in European journal of pharmaceutical sciences (01.02.2021)
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Pharmacokinetics and bioequivalence study of tetramethylpyrazine phosphate tablets after single-dose administration in healthy Chinese male subjects
Li, Houli, Wang, Benjie, Yuan, Guiyan, Guo, Ruichen
Published in International journal of clinical pharmacology and therapeutics (01.08.2018)
Published in International journal of clinical pharmacology and therapeutics (01.08.2018)
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Lack of effect of favipiravir, a novel antiviral agent, on QT interval in healthy Japanese adults
Kumagai, Yuji, Murakawa, Yuji, Hasunuma, Tomoko, Aso, Masako, Yuji, Wakako, Sakurai, Tsutomu, Noto, Masahiko, Oe, Tetsuya, Kaneko, Akiko
Published in International journal of clinical pharmacology and therapeutics (01.10.2015)
Published in International journal of clinical pharmacology and therapeutics (01.10.2015)
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Marked Expansion of Exocrine and Endocrine Pancreas With Incretin Therapy in Humans With Increased Exocrine Pancreas Dysplasia and the Potential for Glucagon-Producing Neuroendocrine Tumors
Butler, Alexandra E., Campbell-Thompson, Martha, Gurlo, Tatyana, Dawson, David W., Atkinson, Mark, Butler, Peter C.
Published in Diabetes (New York, N.Y.) (01.07.2013)
Published in Diabetes (New York, N.Y.) (01.07.2013)
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Molecular Basis for Wine Grape Quality-A Volatile Subject
Lund, Steven T, Bohlmann, Joerg
Published in Science (American Association for the Advancement of Science) (10.02.2006)
Published in Science (American Association for the Advancement of Science) (10.02.2006)
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Effects of JNJ-38431055, a novel GPR119 receptor agonist, in randomized, double-blind, placebo-controlled studies in subjects with type 2 diabetes
Katz, L. B., Gambale, J. J., Rothenberg, P. L., Vanapalli, S. R., Vaccaro, N., Xi, L., Sarich, T. C., Stein, P. P.
Published in Diabetes, obesity & metabolism (01.08.2012)
Published in Diabetes, obesity & metabolism (01.08.2012)
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[ 11 C]ZTP-1: An Effective Short-Lived Radioligand for PET of Rat and Monkey Brain Phosphodiesterase Type 4 Subtype B
Zhao, Qunchao, Liow, Jeih-San, Jee, Joo Eun, Montero Santamaria, Jose, Pamie-George, Matilah, Morse, Cheryl, Wu, Shawn, Zoghbi, Sami S., Kim, Sung Won, Innis, Robert B., Pike, Victor W., Telu, Sanjay
Published in Journal of Nuclear Medicine (01.07.2025)
Published in Journal of Nuclear Medicine (01.07.2025)
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Improved characterization of the pharmacokinetics of acalabrutinib and its pharmacologically active metabolite, ACP‐5862, in patients with B‐cell malignancies and in healthy subjects using a population pharmacokinetic approach
Edlund, Helena, Bellanti, Francesco, Liu, Huan, Vishwanathan, Karthick, Tomkinson, Helen, Ware, Joseph, Sharma, Shringi, Buil‐Bruna, Núria
Published in British journal of clinical pharmacology (01.02.2022)
Published in British journal of clinical pharmacology (01.02.2022)
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Efficacy and safety profile of sitagliptin, vildagliptin, and metformin in newly diagnosed type 2 diabetic subjects
Elhini, Sahar Hossam, Hussien, Amal K., Omran, Ahmed Abd Elsamie, Elsayed, Asmaa A., saeed, Haitham
Published in Clinical and experimental pharmacology & physiology (01.12.2021)
Published in Clinical and experimental pharmacology & physiology (01.12.2021)
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