Chronic kidney disease induced by an adenine rich diet upregulates integrin linked kinase (ILK) and its depletion prevents the disease progression
de Frutos, Sergio, Luengo, Alicia, García-Jérez, Andrea, Hatem-Vaquero, Marco, Griera, Mercedes, O'Valle, Francisco, Rodríguez–Puyol, Manuel, Rodríguez–Puyol, Diego, Calleros, Laura
Published in Biochimica et biophysica acta. Molecular basis of disease (01.06.2019)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.06.2019)
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Hyperphosphatemia induces senescence in human endothelial cells by increasing endothelin‐1 production
Olmos, Gemma, Martínez‐Miguel, Patricia, Alcalde‐Estevez, Elena, Medrano, Diana, Sosa, Patricia, Rodríguez‐Mañas, Leocadio, Naves‐Diaz, Manuel, Rodríguez‐Puyol, Diego, Ruiz‐Torres, María Piedad, López‐Ongil, Susana
Published in Aging cell (01.12.2017)
Published in Aging cell (01.12.2017)
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A Computer‐Driven Scaffold‐Hopping Approach Generating New PTP1B Inhibitors from the Pyrrolo[1,2‐a]quinoxaline Core
García‐Marín, Javier, Griera, Mercedes, Alajarín, Ramón, Rodríguez‐Puyol, Manuel, Rodríguez‐Puyol, Diego, Vaquero, Juan J.
Published in ChemMedChem (16.09.2021)
Published in ChemMedChem (16.09.2021)
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Comparison of 2 medium cutoff dialyzers versus on‐line hemodiafiltration regarding depurative ability and albumin loss: An uncontrolled clinical research
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Published in Artificial organs (01.03.2023)
Published in Artificial organs (01.03.2023)
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Impaired erythropoietin synthesis in chronic kidney disease is caused by alterations in extracellular matrix composition
Olmos, Gemma, Muñoz‐Félix, José M., Mora, Inés, Müller, Anton Gerhard, Ruiz‐Torres, Maria Piedad, López‐Novoa, José M., Rodríguez‐Puyol, Diego
Published in Journal of cellular and molecular medicine (01.01.2018)
Published in Journal of cellular and molecular medicine (01.01.2018)
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Uraemic toxins impair skeletal muscle regeneration by inhibiting myoblast proliferation, reducing myogenic differentiation, and promoting muscular fibrosis
Alcalde-Estévez, Elena, Sosa, Patricia, Asenjo-Bueno, Ana, Plaza, Patricia, Olmos, Gemma, Naves-Díaz, Manuel, Rodríguez-Puyol, Diego, López-Ongil, Susana, Ruiz-Torres, María P
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Published in Scientific reports (12.01.2021)
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Use of renin–angiotensin–aldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case-population study
de Abajo, Francisco J, Rodríguez-Martín, Sara, Lerma, Victoria, Mejía-Abril, Gina, Aguilar, Mónica, García-Luque, Amelia, Laredo, Leonor, Laosa, Olga, Centeno-Soto, Gustavo A, Ángeles Gálvez, Maria, Puerro, Miguel, González-Rojano, Esperanza, Pedraza, Laura, de Pablo, Itziar, Abad-Santos, Francisco, Rodríguez-Mañas, Leocadio, Gil, Miguel, Tobías, Aurelio, Rodríguez-Miguel, Antonio, Rodríguez-Puyol, Diego, Barreira-Hernandez, D, Zubiaur, P, Santos-Molina, E, Pintos-Sánchez, E, Navares-Gómez, M, Aparicio, R M, García-Rosado, V, Gutiérrez-Ortega, C, Pérez, C, Ascaso, A, Elvira, C
Published in The Lancet (30.05.2020)
Published in The Lancet (30.05.2020)
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Indoxyl sulfate- and P-cresol-induced monocyte adhesion and migration is mediated by integrin-linked kinase-dependent podosome formation
Campillo, Sofía, Bohorquez, Lourdes, Gutiérrez-Calabrés, Elena, García-Ayuso, Diego, Miguel, Verónica, Griera, Mercedes, Calle, Yolanda, de Frutos, Sergio, Rodríguez-Puyol, Manuel, Rodríguez-Puyol, Diego, Calleros, Laura
Published in Experimental & molecular medicine (01.03.2022)
Published in Experimental & molecular medicine (01.03.2022)
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Effective glutamate clearance from the systemic circulation by hemodialysis: Potential relevance for cerebral ischemia management
Martínez‐Miguel, Patricia, Albalate, Marta, Durán‐Laforet, Violeta, Peña‐Martínez, Carolina, Sequera, Patricia, Bouarich, Hanane, Peña‐Esparragoza, Korina, López‐Ongil, Susana, Lizasoain, Ignacio, Sánchez‐Prieto, José, Torres, Magdalena, Moro, María Ángeles, Rodríguez‐Puyol, Diego
Published in Artificial organs (01.10.2021)
Published in Artificial organs (01.10.2021)
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H- ras deletion protects against angiotensin II-induced arterial hypertension and cardiac remodeling through protein kinase G-Iβ pathway activation
Martín-Sánchez, Paloma, Luengo, Alicia, Griera, Mercedes, Orea, María Jesús, López-Olañeta, Marina, Chiloeches, Antonio, Lara-Pezzi, Enrique, de Frutos, Sergio, Rodríguez-Puyol, Manuel, Calleros, Laura, Rodríguez-Puyol, Diego
Published in The FASEB journal (01.02.2018)
Published in The FASEB journal (01.02.2018)
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Tripeptides as Integrin-Linked Kinase Modulating Agents Based on a Protein–Protein Interaction with α‑Parvin
Garcia-Marin, Javier, Griera-Merino, Mercedes, Matamoros-Recio, Alejandra, de Frutos, Sergio, Rodríguez-Puyol, Manuel, Alajarín, Ramón, Vaquero, Juan J, Rodríguez-Puyol, Diego
Published in ACS medicinal chemistry letters (11.11.2021)
Published in ACS medicinal chemistry letters (11.11.2021)
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Integrin-linked kinase plays a key role in the regulation of angiotensin II-induced renal inflammation
Alique, Matilde, Civantos, Esther, Sanchez-Lopez, Elsa, Lavoz, Carolina, Rayego-Mateos, Sandra, Rodrigues-Díez, Raquel, García-Redondo, Ana Belén, Egido, Jesús, Ortiz, Alberto, Rodríguez-Puyol, Diego, Rodríguez-Puyol, Manuel, Ruiz-Ortega, Marta
Published in Clinical science (1979) (01.07.2014)
Published in Clinical science (1979) (01.07.2014)
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Effects of a Losartan-Antioxidant Hybrid (GGN1231) on Vascular and Cardiac Health in an Experimental Model of Chronic Renal Failure
Martínez-Arias, Laura, Fernández-Villabrille, Sara, Alonso-Montes, Cristina, García-Navazo, Gonzalo, Ruíz-Torres, María P, Alajarín, Ramón, Alvarez-Builla, Julio, Gutiérrez-Calabres, Elena, Vaquero-López, Juan José, Carrillo-López, Natalia, Rodríguez-Puyol, Diego, Cannata-Andía, Jorge B, Panizo, Sara, Naves-Díaz, Manuel
Published in Nutrients (01.04.2023)
Published in Nutrients (01.04.2023)
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Integrin-linked kinase regulates tubular aquaporin-2 content and intracellular location: a link between the extracellular matrix and water reabsorption
Cano-Peñalver, Jose Luis, Griera, Mercedes, Serrano, Isabel, Rodríguez-Puyol, Diego, Dedhar, Shoukat, de Frutos, Sergio, Rodríguez-Puyol, Manuel
Published in The FASEB journal (01.08.2014)
Published in The FASEB journal (01.08.2014)
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Losartan-Antioxidant Hybrids: Novel Molecules for the Prevention of Hypertension-Induced Cardiovascular Damage
García, Gonzalo, Rodríguez-Puyol, Manuel, Alajarín, Ramón, Serrano, Isabel, Sánchez-Alonso, Patricia, Griera, Mercedes, Vaquero, Juan J, Rodríguez-Puyol, Diego, Álvarez-Builla, Julio, Díez-Marqués, María L
Published in Journal of medicinal chemistry (26.11.2009)
Published in Journal of medicinal chemistry (26.11.2009)
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Atherosclerosis in Chronic Kidney Disease: More, Less, or Just Different?
Valdivielso, José M, Rodríguez-Puyol, Diego, Pascual, Julio, Barrios, Clara, Bermúdez-López, Marcelino, Sánchez-Niño, Maria Dolores, Pérez-Fernández, María, Ortiz, Alberto
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2019)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2019)
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Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis
Miguel, Verónica, Tituaña, Jessica, Herrero, J Ignacio, Herrero, Laura, Serra, Dolors, Cuevas, Paula, Barbas, Coral, Puyol, Diego Rodríguez, Márquez-Expósito, Laura, Ruiz-Ortega, Marta, Castillo, Carolina, Sheng, Xin, Susztak, Katalin, Ruiz-Canela, Miguel, Salas-Salvadó, Jordi, González, Miguel A Martínez, Ortega, Sagrario, Ramos, Ricardo, Lamas, Santiago
Published in The Journal of clinical investigation (01.03.2021)
Published in The Journal of clinical investigation (01.03.2021)
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Interplay between extracellular matrix components and cellular and molecular mechanisms in kidney fibrosis
Rayego-Mateos, Sandra, Campillo, Sofia, Rodrigues-Diez, Raúl R, Tejera-Muñoz, Antonio, Marquez-Exposito, Laura, Goldschmeding, Roel, Rodríguez-Puyol, Diego, Calleros, Laura, Ruiz-Ortega, Marta
Published in Clinical science (1979) (27.08.2021)
Published in Clinical science (1979) (27.08.2021)
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Improvement of mineral and bone metabolism markers is associated with better survival in haemodialysis patients: the COSMOS study
Fernández-Martín, José Luis, Martínez-Camblor, Pablo, Dionisi, María Paula, Floege, Jürgen, Ketteler, Markus, London, Gérard, Locatelli, Francesco, Gorriz, José Luis, Rutkowski, Boleslaw, Ferreira, Aníbal, Bos, Willem-Jan, Covic, Adrian, Rodríguez-García, Minerva, Sánchez, José Emilio, Rodríguez-Puyol, Diego, Cannata-Andia, Jorge B
Published in Nephrology, dialysis, transplantation (01.09.2015)
Published in Nephrology, dialysis, transplantation (01.09.2015)
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