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Yeku, Oladapo O., Purdon, Terence J., Koneru, Mythili, Spriggs, David, Brentjens, Renier J.
Published in Scientific reports (05.09.2017)
Published in Scientific reports (05.09.2017)
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GPRC5D-Targeted CAR T Cells for Myeloma
Mailankody, Sham, Devlin, Sean M., Landa, Jonathan, Nath, Karthik, Diamonte, Claudia, Carstens, Elizabeth J., Russo, Douglas, Auclair, Romany, Fitzgerald, Lisa, Cadzin, Briana, Wang, Xiuyan, Sikder, Devanjan, Senechal, Brigitte, Bermudez, Vladimir P., Purdon, Terence J., Hosszu, Kinga, McAvoy, Devin P., Farzana, Tasmin, Mead, Elena, Wilcox, Jessica A., Santomasso, Bianca D., Shah, Gunjan L., Shah, Urvi A., Korde, Neha, Lesokhin, Alexander, Tan, Carlyn R., Hultcrantz, Malin, Hassoun, Hani, Roshal, Mikhail, Sen, Filiz, Dogan, Ahmet, Landgren, Ola, Giralt, Sergio A., Park, Jae H., Usmani, Saad Z., Rivière, Isabelle, Brentjens, Renier J., Smith, Eric L.
Published in The New England journal of medicine (29.09.2022)
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Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages
Song, Mei, Yeku, Oladapo O., Rafiq, Sarwish, Purdon, Terence, Dong, Xue, Zhu, Lijing, Zhang, Tuo, Wang, Huan, Yu, Ziqi, Mai, Junhua, Shen, Haifa, Nixon, Briana, Li, Ming, Brentjens, Renier J., Ma, Xiaojing
Published in Nature communications (08.12.2020)
Published in Nature communications (08.12.2020)
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IL-12 secreting tumor-targeted chimeric antigen receptor T cells eradicate ovarian tumors in vivo
Koneru, Mythili, Purdon, Terence J., Spriggs, David, Koneru, Susmith, Brentjens, Renier J.
Published in Oncoimmunology (01.03.2015)
Published in Oncoimmunology (01.03.2015)
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Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo
Rafiq, Sarwish, Yeku, Oladapo O, Jackson, Hollie J, Purdon, Terence J, van Leeuwen, Dayenne G, Drakes, Dylan J, Song, Mei, Miele, Matthew M, Li, Zhuoning, Wang, Pei, Yan, Su, Xiang, Jingyi, Ma, Xiaojing, Seshan, Venkatraman E, Hendrickson, Ronald C, Liu, Cheng, Brentjens, Renier J
Published in Nature biotechnology (01.10.2018)
Published in Nature biotechnology (01.10.2018)
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CD40 Ligand-Modified Chimeric Antigen Receptor T Cells Enhance Antitumor Function by Eliciting an Endogenous Antitumor Response
Kuhn, Nicholas F., Purdon, Terence J., van Leeuwen, Dayenne G., Lopez, Andrea V., Curran, Kevin J., Daniyan, Anthony F., Brentjens, Renier J.
Published in Cancer cell (18.03.2019)
Published in Cancer cell (18.03.2019)
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Cytokine IL-36γ improves CAR T-cell functionality and induces endogenous antitumor response
Li, Xinghuo, Daniyan, Anthony F., Lopez, Andrea V., Purdon, Terence J., Brentjens, Renier J.
Published in Leukemia (01.02.2021)
Published in Leukemia (01.02.2021)
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Engineered Tumor-Targeted T Cells Mediate Enhanced Anti-Tumor Efficacy Both Directly and through Activation of the Endogenous Immune System
Avanzi, Mauro P., Yeku, Oladapo, Li, Xinghuo, Wijewarnasuriya, Dinali P., van Leeuwen, Dayenne G., Cheung, Kenneth, Park, Hyebin, Purdon, Terence J., Daniyan, Anthony F., Spitzer, Matthew H., Brentjens, Renier J.
Published in Cell reports (Cambridge) (15.05.2018)
Published in Cell reports (Cambridge) (15.05.2018)
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GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells
Smith, Eric L, Harrington, Kim, Staehr, Mette, Masakayan, Reed, Jones, Jon, Long, Thomas J, Ng, Khong Y, Ghoddusi, Majid, Purdon, Terence J, Wang, Xiuyan, Do, Trevor, Pham, Minh Thu, Brown, Jessica M, De Larrea, Carlos Fernandez, Olson, Eric, Peguero, Elizabeth, Wang, Pei, Liu, Hong, Xu, Yiyang, Garrett-Thomson, Sarah C, Almo, Steven C, Wendel, Hans-Guido, Riviere, Isabelle, Liu, Cheng, Sather, Blythe, Brentjens, Renier J
Published in Science translational medicine (27.03.2019)
Published in Science translational medicine (27.03.2019)
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Development and Evaluation of an Optimal Human Single-Chain Variable Fragment-Derived BCMA-Targeted CAR T Cell Vector
Smith, Eric L., Staehr, Mette, Masakayan, Reed, Tatake, Ishan J., Purdon, Terence J., Wang, Xiuyan, Wang, Pei, Liu, Hong, Xu, Yiyang, Garrett-Thomson, Sarah C., Almo, Steven C., Riviere, Isabelle, Liu, Cheng, Brentjens, Renier J.
Published in Molecular therapy (06.06.2018)
Published in Molecular therapy (06.06.2018)
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Autologous CD19-Targeted CAR T Cells in Patients with Residual CLL following Initial Purine Analog-Based Therapy
Geyer, Mark B., Rivière, Isabelle, Sénéchal, Brigitte, Wang, Xiuyan, Wang, Yongzeng, Purdon, Terence J., Hsu, Meier, Devlin, Sean M., Halton, Elizabeth, Lamanna, Nicole, Rademaker, Jurgen, Sadelain, Michel, Brentjens, Renier J., Park, Jae H.
Published in Molecular therapy (01.08.2018)
Published in Molecular therapy (01.08.2018)
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Defining an Optimal Dual-Targeted CAR T-cell Therapy Approach Simultaneously Targeting BCMA and GPRC5D to Prevent BCMA Escape-Driven Relapse in Multiple Myeloma
Fernández de Larrea, Carlos, Staehr, Mette, Lopez, Andrea V, Ng, Khong Y, Chen, Yunxin, Godfrey, William D, Purdon, Terence J, Ponomarev, Vladimir, Wendel, Hans-Guido, Brentjens, Renier J, Smith, Eric L
Published in Blood cancer discovery (01.09.2020)
Published in Blood cancer discovery (01.09.2020)
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Hematopoietic recovery in patients receiving chimeric antigen receptor T-cell therapy for hematologic malignancies
Jain, Tania, Knezevic, Andrea, Pennisi, Martina, Chen, Yunxin, Ruiz, Josel D., Purdon, Terence J., Devlin, Sean M., Smith, Melody, Shah, Gunjan L., Halton, Elizabeth, Diamonte, Claudia, Scordo, Michael, Sauter, Craig S., Mead, Elena, Santomasso, Bianca D., Palomba, M. Lia, Batlevi, Connie W., Maloy, Molly A., Giralt, Sergio, Smith, Eric, Brentjens, Renier, Park, Jae H., Perales, Miguel-Angel, Mailankody, Sham
Published in Blood advances (11.08.2020)
Published in Blood advances (11.08.2020)
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Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition
Yeku, Oladapo O, Rao, Thapi Dharma, Laster, Ian, Kononenko, Artem, Purdon, Terence J, Wang, Pei, Cui, Ziyou, Liu, Hong, Brentjens, Renier J, Spriggs, David
Published in Frontiers in immunology (14.04.2021)
Published in Frontiers in immunology (14.04.2021)
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BCMA-Targeted CAR T-cell Therapy plus Radiotherapy for the Treatment of Refractory Myeloma Reveals Potential Synergy
Smith, Eric L, Mailankody, Sham, Staehr, Mette, Wang, Xiuyan, Senechal, Brigitte, Purdon, Terence J, Daniyan, Anthony F, Geyer, Mark B, Goldberg, Aaron D, Mead, Elena, Santomasso, Bianca D, Landa, Jonathan, Rimner, Andreas, Riviere, Isabelle, Landgren, Ola, Brentjens, Renier J
Published in Cancer immunology research (01.07.2019)
Published in Cancer immunology research (01.07.2019)
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Safety and tolerability of conditioning chemotherapy followed by CD19-targeted CAR T cells for relapsed/refractory CLL
Geyer, Mark B, Rivière, Isabelle, Sénéchal, Brigitte, Wang, Xiuyan, Wang, Yongzeng, Purdon, Terence J, Hsu, Meier, Devlin, Sean M, Palomba, M Lia, Halton, Elizabeth, Bernal, Yvette, van Leeuwen, Dayenne G, Sadelain, Michel, Park, Jae H, Brentjens, Renier J
Published in JCI insight (02.05.2019)
Published in JCI insight (02.05.2019)
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Correlation of IL-6 secretion and hyponatremia with the use of CD19+ chimeric antigen receptor T-cells
Dixon, Brianne N, Daley, Ryan J, Buie, Larry W, Hsu, Meier, Park, Jae H, Brentjens, Renier J, Purdon, Terence J, Latcha, Sheron
Published in Clinical nephrology (01.01.2020)
Published in Clinical nephrology (01.01.2020)
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Augmenting CAR T Cell Functions with LIGHT
Cai, Winson, Tanaka, Kento, Mi, Xiaoli, Rajasekhar, Vinagolu K, Khan, Jonathan F, Yoo, Sarah, de Stanchina, Elisa, Rahman, Jahan, Mathew, Serena, Abrahimi, Parwiz, Souness, Sydney, Purdon, Terence J, McDowell, James R, Meyerberg, Jeremy, Fujino, Takeshi, Healey, John H, Abdel-Wahab, Omar, Scheinberg, David A, Brentjens, Renier J, Daniyan, Anthony F
Published in Cancer immunology research (01.10.2024)
Published in Cancer immunology research (01.10.2024)
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TYRP1 directed CAR T cells control tumor progression in preclinical melanoma models
Hackett, Christopher S, Hirschhorn, Daniel, Tang, Meixian S, Purdon, Terence J, Marouf, Yacine, Piersigilli, Alessandra, Agaram, Narasimhan P, Liu, Cailian, Schad, Sara E, de Stanchina, Elisa, Rafiq, Sarwish, Monette, Sebastien, Wolchok, Jedd D, Merghoub, Taha, Brentjens, Renier J
Published in Molecular Therapy: Oncology (19.09.2024)
Published in Molecular Therapy: Oncology (19.09.2024)
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