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ADP-induced platelet aggregation and platelet reactivity index VASP are good predictive markers for clinical outcomes in non-ST elevation acute coronary syndrome
Frere, Corinne, Cuisset, Thomas, Quilici, Jacques, Camoin, Laurence, Carvajal, Joseph, Morange, Pierre Emmanuel, Lambert, Marc, Juhan-Vague, Irène, Bonnet, Jean-Louis, Alessi, Marie-Christine
Published in Thrombosis and haemostasis (01.10.2007)
Published in Thrombosis and haemostasis (01.10.2007)
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The first in‐human study to evaluate the antiplatelet properties of the clopidogrel conjugate DT‐678 in acute coronary syndrome patients and healthy volunteers
Liu, Zhihao, Liu, Shengcong, Gong, Yanjun, Chi, Xiying, Wang, Ting, Fan, Fangfang, Qu, Chenxue, Lou, Yaxin, Zhang, Long, Zhang, Bin, Yang, Fan, Mohetaboer, Momin, Wang, Jie, Qiu, Lin, Miao, Linzi, Lu, Yao, You, Ran, He, Pengkang, Li, Yuxi, Yi, Tieci, Weng, Haoyu, Xia, Yulong, Wang, Chunyan, Shi, Qiuping, Wang, Zhi, Jiang, Yimeng, Li, Yinjuan, Han, Chunyu, Wang, Yu, Wang, Xinghe, Yang, Caixia, Chen, Y. Eugene, Eitzman, Daniel T., Zhang, Haoming, Li, Jianping
Published in British journal of pharmacology (01.01.2025)
Published in British journal of pharmacology (01.01.2025)
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Effects of ilaprazole on the steady-state pharmacodynamics of clopidogrel in healthy volunteers: An open-label randomized crossover study
Ye, Zekang, Chen, Pengsheng, Tan, Chuchu, Gong, Xiaoxuan, Li, Ran, Dong, Zhou, Ullah, Inam, Zhou, Chen, Zhou, Sufeng, Xie, Lijun, Hou, Xuemei, Han, Zhihui, Gu, Qian, Ma, Jiazheng, Teng, Jianzhen, Tang, Yingdan, Zhang, Zhuanxia, Hu, Haitang, Zhuang, Quankun, Chen, Juan, Zhu, Bei, Shao, Feng, Li, Chunjian
Published in Frontiers in pharmacology (08.09.2022)
Published in Frontiers in pharmacology (08.09.2022)
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Cell Surface Platelet Tissue Factor Expression: Regulation by P2Y12 and Link to Residual Platelet Reactivity
Brambilla, Marta, Becchetti, Alessia, Rovati, Gian Enrico, Cosentino, Nicola, Conti, Maria, Canzano, Paola, Giesen, Peter L.A., Loffreda, Alessia, Bonomi, Alice, Cattaneo, Marco, De Candia, Erica, Podda, Gian Marco, Trabattoni, Daniela, Werba, Pablo Josè, Campodonico, Jeness, Pinna, Christian, Marenzi, Giancarlo, Tremoli, Elena, Camera, Marina
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2023)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2023)
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Differential effects of omeprazole and pantoprazole on the pharmacodynamics and pharmacokinetics of clopidogrel in healthy subjects: randomized, placebo-controlled, crossover comparison studies
Angiolillo, D J, Gibson, C M, Cheng, S, Ollier, C, Nicolas, O, Bergougnan, L, Perrin, L, LaCreta, F P, Hurbin, F, Dubar, M
Published in Clinical pharmacology and therapeutics (01.01.2011)
Published in Clinical pharmacology and therapeutics (01.01.2011)
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A Randomized, 2-Period, Crossover Design Study to Assess the Effects of Dexlansoprazole, Lansoprazole, Esomeprazole, and Omeprazole on the Steady-State Pharmacokinetics and Pharmacodynamics of Clopidogrel in Healthy Volunteers
Frelinger, Andrew L., Lee, Ronald D., Mulford, Darcy J., Wu, Jingtao, Nudurupati, Sai, Nigam, Anu, Brooks, Julie K., Bhatt, Deepak L., Michelson, Alan D.
Published in Journal of the American College of Cardiology (03.04.2012)
Published in Journal of the American College of Cardiology (03.04.2012)
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Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease
Wallentin, Lars, Varenhorst, Christoph, James, Stefan, Erlinge, David, Braun, Oscar Ö, Jakubowski, Joseph A., Sugidachi, Atsuhiro, Winters, Kenneth J., Siegbahn, Agneta
Published in European heart journal (2008)
Published in European heart journal (2008)
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Dosing Clopidogrel Based on CYP2C19 Genotype and the Effect on Platelet Reactivity in Patients With Stable Cardiovascular Disease
Mega, Jessica L, Hochholzer, Willibald, Frelinger, Andrew L, Kluk, Michael J, Angiolillo, Dominick J, Kereiakes, Dean J, Isserman, Steven, Rogers, William J, Ruff, Christian T, Contant, Charles, Pencina, Michael J, Scirica, Benjamin M, Longtine, Janina A, Michelson, Alan D, Sabatine, Marc S
Published in JAMA : the journal of the American Medical Association (23.11.2011)
Published in JAMA : the journal of the American Medical Association (23.11.2011)
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A phase 1 study of prasugrel in patients with sickle cell disease: pharmacokinetics and effects on ex vivo platelet reactivity
Jakubowski, Joseph A., Zhou, Chunmei, Small, David S., Winters, Kenneth J., Lachno, D. Richard, Frelinger, Andrew L., Howard, Jo, Mant, Timothy G., Jurcevic, Stipo, Payne, Christopher D.
Published in British journal of clinical pharmacology (01.06.2013)
Published in British journal of clinical pharmacology (01.06.2013)
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Clopidogrel Pharmacokinetics and Pharmacodynamics Vary Widely Despite Exclusion or Control of Polymorphisms (CYP2C19, ABCB1, PON1), Noncompliance, Diet, Smoking, Co-Medications (Including Proton Pump Inhibitors), and Pre-Existent Variability in Platelet Function
Frelinger, Andrew L., Bhatt, Deepak L., Lee, Ronald D., Mulford, Darcy J., Wu, Jingtao, Nudurupati, Sai, Nigam, Anu, Lampa, Michael, Brooks, Julie K., Barnard, Marc R., Michelson, Alan D.
Published in Journal of the American College of Cardiology (26.02.2013)
Published in Journal of the American College of Cardiology (26.02.2013)
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Decreased platelet miR-223 expression is associated with high on-clopidogrel platelet reactivity
Shi, Rui, Ge, Lan, Zhou, Xin, Ji, Wen-Jie, Lu, Rui-Yi, Zhang, Ying-Ying, Zeng, Shan, Liu, Xing, Zhao, Ji-Hong, Zhang, Wen-Cheng, Jiang, Tie-Min, Li, Yu-Ming
Published in Thrombosis research (01.06.2013)
Published in Thrombosis research (01.06.2013)
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Decreased circulating microRNA-223 level predicts high on-treatment platelet reactivity in patients with troponin-negative non-ST elevation acute coronary syndrome
Zhang, Ying-Ying, Zhou, Xin, Ji, Wen-Jie, Shi, Rui, Lu, Rui-Yi, Li, Jin-Long, Yang, Guo-Hong, Luo, Tao, Zhang, Jian-Qi, Zhao, Ji-Hong, Jiang, Tie-Min, Li, Yu-Ming
Published in Journal of thrombosis and thrombolysis (01.07.2014)
Published in Journal of thrombosis and thrombolysis (01.07.2014)
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The Influence of Smoking Status on the Pharmacokinetics and Pharmacodynamics of Clopidogrel and Prasugrel: The PARADOX Study
GURBEL, Paul A, BLIDEN, Kevin P, JAKUBOWSKI, Joseph A, OJEH, Clement K, JEONG, Young-Hoon, TANTRY, Udaya S, BAKER, Brian A, LOGAN, Douglas K, KEREIAKES, Dean J, LASSETER, Kenneth C, WHITE, Alex, ANGIOLILLO, Dominick J, NOLIN, Thomas D, MAA, Jen-Fue, BAILEY, William L
Published in Journal of the American College of Cardiology (06.08.2013)
Published in Journal of the American College of Cardiology (06.08.2013)
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Impact of red blood cell transfusion on platelet activation and aggregation in healthy volunteers: results of the TRANSFUSION study
Silvain, Johanne, Pena, Ana, Cayla, Guillaume, Brieger, David, Bellemain-Appaix, Anne, Chastre, Thomas, Vignalou, Jean-Baptiste, Beygui, Farzin, Barthelemy, Olivier, Collet, Jean-Philippe, Montalescot, Gilles
Published in European heart journal (01.11.2010)
Published in European heart journal (01.11.2010)
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A comparison of the antiplatelet effects of prasugrel and high-dose clopidogrel as assessed by VASP-phosphorylation and light transmission aggregometry
Jakubowski, Joseph A, Payne, Christopher D, Li, Ying G, Farid, Nagy A, Brandt, John T, Small, David S, Salazar, Daniel E, Winters, Kenneth J
Published in Thrombosis and haemostasis (01.01.2008)
Published in Thrombosis and haemostasis (01.01.2008)
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Decrease in high on-treatment platelet reactivity (HPR) prevalence on switching from clopidogrel to prasugrel: insights from the switching anti-platelet (SWAP) study
Saucedo, Jorge F, Angiolillo, Dominick J, DeRaad, Roger, Frelinger, 3rd, Andrew L, Gurbel, Paul A, Costigan, Timothy M, Jakubowski, Joseph A, Ojeh, Clement K, Duvvuru, Suman, Effron, Mark B
Published in Thrombosis and haemostasis (01.02.2013)
Published in Thrombosis and haemostasis (01.02.2013)
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Association of PEAR1 rs12041331 polymorphism and pharmacodynamics of ticagrelor in healthy Chinese volunteers
Li, Mupeng, Hu, Yaodong, Wen, Zhipeng, Li, Huilan, Hu, Xiaolei, Zhang, Yanjiao, Zhang, Zanling, Xiao, Jian, Tang, Jie, Chen, Xiaoping
Published in Xenobiotica (02.12.2017)
Published in Xenobiotica (02.12.2017)
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Pharmacodynamic effects of standard dose prasugrel versus high dose clopidogrel in non-diabetic obese patients with coronary artery disease
Darlington, Andrew, Tello-Montoliu, Antonio, Rollini, Fabiana, Ueno, Masafumi, Ferreiro, José Luis, Patel, Ronakkumar, Desai, Bhaloo, Guzman, Luis A, Bass, Theodore A, Angiolillo, Dominick J
Published in Thrombosis and haemostasis (01.02.2014)
Published in Thrombosis and haemostasis (01.02.2014)
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Influence of Omeprazole on the Antiplatelet Action of Clopidogrel Associated With Aspirin
Gilard, Martine, Arnaud, Bertrand, Cornily, Jean-Christophe, Le Gal, Grégoire, Lacut, Karine, Le Calvez, Geneviève, Mansourati, Jacques, Mottier, Dominique, Abgrall, Jean-François, Boschat, Jacques
Published in Journal of the American College of Cardiology (22.01.2008)
Published in Journal of the American College of Cardiology (22.01.2008)
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