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Physiologically‐based pharmacokinetic model‐based translation of OATP1B‐mediated drug–drug interactions from coproporphyrin I to probe drugs
Mochizuki, Tatsuki, Aoki, Yasunori, Yoshikado, Takashi, Yoshida, Kenta, Lai, Yurong, Hirabayashi, Hideki, Yamaura, Yoshiyuki, Rockich, Kevin, Taskar, Kunal, Takashima, Tadayuki, Chu, Xiaoyan, Zamek‐Gliszczynski, Maciej J., Mao, Jialin, Maeda, Kazuya, Furihata, Kenichi, Sugiyama, Yuichi, Kusuhara, Hiroyuki
Published in Clinical and translational science (01.06.2022)
Published in Clinical and translational science (01.06.2022)
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Development of a Physiologically Based Pharmacokinetic Model for Prediction of Pramipexole Pharmacokinetics in Parkinson's Disease Patients With Renal Impairment
You, Xiang, Wu, Wanhong, Xu, Jing, Jiao, Zheng, Ke, Meng, Huang, Pinfang, Lin, Cuihong
Published in Journal of clinical pharmacology (01.08.2020)
Published in Journal of clinical pharmacology (01.08.2020)
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Robust physiologically based pharmacokinetic model of rifampicin for predicting drug–drug interactions via P‐glycoprotein induction and inhibition in the intestine, liver, and kidney
Asaumi, Ryuta, Nunoya, Ken‐ichi, Yamaura, Yoshiyuki, Taskar, Kunal S., Sugiyama, Yuichi
Published in CPT: pharmacometrics and systems pharmacology (01.07.2022)
Published in CPT: pharmacometrics and systems pharmacology (01.07.2022)
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Physiologically Based Pharmacokinetic Model of Cefotaxime in Patients with Impaired Renal Function: PBPK Modeling of Cefotaxime in Patients with Kidney Disease
Zbib, Fatima, Deschamps, Anthéa, Velly, Lionel, Blin, Olivier, Guilhaumou, Romain, Gattacceca, Florence
Published in Clinical pharmacokinetics (01.02.2025)
Published in Clinical pharmacokinetics (01.02.2025)
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Physiologically‐based pharmacokinetic model to investigate the effect of pregnancy on risperidone and paliperidone pharmacokinetics: Application to a pregnant woman and her neonate
Mahdy, Walaa Y. B., Yamamoto, Kazuhiro, Ito, Takahiro, Fujiwara, Naoko, Fujioka, Kazumichi, Horai, Tadasu, Otsuka, Ikuo, Imafuku, Hitomi, Omura, Tomohiro, Iijima, Kazumoto, Yano, Ikuko
Published in Clinical and translational science (01.04.2023)
Published in Clinical and translational science (01.04.2023)
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Physiologically Based Pharmacokinetic Model of All-trans-Retinoic Acid with Application to Cancer Populations and Drug Interactions
Jing, Jing, Nelson, Cara, Paik, Jisun, Shirasaka, Yoshiyuki, Amory, John K., Isoherranen, Nina
Published in The Journal of pharmacology and experimental therapeutics (01.05.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2017)
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Virtual Bioequivalence Assessment of Ritlecitinib Capsules with Incorporation of Observed Clinical Variability Using a Physiologically Based Pharmacokinetic Model
Saadeddin, Anas, Purohit, Vivek, Huh, Yeamin, Wong, Mei, Maulny, Aurelia, Dowty, Martin E., Sagawa, Kazuko
Published in The AAPS journal (24.01.2024)
Published in The AAPS journal (24.01.2024)
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Assessment of Quinidine-Induced Torsades de Pointes Risks Using a Whole-Body Physiologically Based Pharmacokinetic Model Linked to Cardiac Ionic Current Inhibition
Zhang, Zexin, Zhou, Han, Yang, Yiting, Liu, Li, Liu, Xiaodong
Published in Clinical pharmacology and therapeutics (01.03.2024)
Published in Clinical pharmacology and therapeutics (01.03.2024)
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Optimizing Maternal and Fetal Antibody Exposure and Dosing Regimens During Pregnancy Using a Physiologically Based Pharmacokinetic Model
Kardouh, Miramar Sami, Dunlap, Tyler C, Zhong, Rui, Tiley, Jacqueline B, Cao, Yanguang
Published in Clinical pharmacology and therapeutics (01.08.2025)
Published in Clinical pharmacology and therapeutics (01.08.2025)
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Development and verification of a physiologically based pharmacokinetic model of dronedarone and its active metabolite N‐desbutyldronedarone: Application to prospective simulation of complex drug–drug interaction with rivaroxaban
Leow, Jacqueline Wen Hui, Ang, Xiao Jun, Chan, Eric Chun Yong
Published in British journal of clinical pharmacology (01.06.2023)
Published in British journal of clinical pharmacology (01.06.2023)
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Comprehensive Physiologically Based Pharmacokinetic Model to Assess Drug–Drug Interactions of Phenytoin
Rodriguez-Vera, Leyanis, Yin, Xuefen, Almoslem, Mohammed, Romahn, Karolin, Cicali, Brian, Lukacova, Viera, Cristofoletti, Rodrigo, Schmidt, Stephan
Published in Pharmaceutics (01.10.2023)
Published in Pharmaceutics (01.10.2023)
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Quantitative Prediction of the Effect of CYP3A Inhibitors and Inducers on Venetoclax Pharmacokinetics Using a Physiologically Based Pharmacokinetic Model
Freise, Kevin J, Shebley, Mohamad, Salem, Ahmed Hamed
Published in Journal of clinical pharmacology (01.06.2017)
Published in Journal of clinical pharmacology (01.06.2017)
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Physiologically‐based pharmacokinetic model for alectinib, ruxolitinib, and panobinostat in the presence of cancer, renal impairment, and hepatic impairment
Alsmadi, Mo'tasem M., AL‐Daoud, Nour M, Jaradat, Mays M., Alzughoul, Saja B., Abu Kwiak, Amani D., Abu Laila, Salam S., Abu Shameh, Ayat J., Alhazabreh, Mohammad K., Jaber, Sana'a A., Abu Kassab, Hala T.
Published in Biopharmaceutics & drug disposition (01.06.2021)
Published in Biopharmaceutics & drug disposition (01.06.2021)
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Translational minimal physiologically based pharmacokinetic model for transferrin receptor-mediated brain delivery of antibodies
Muliaditan, Morris, van Steeg, Tamara J., Avery, Lindsay B., Sun, Wei, Hammond, Timothy R., Hijdra, Diana, Choi, Siak-Leng, Pillai, Nikhil, Leksa, Nina C., Mavroudis, Panteleimon D.
Published in mAbs (01.12.2025)
Published in mAbs (01.12.2025)
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Data‐driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment
Fendt, Rebekka, Hofmann, Ute, Schneider, Annika R. P., Schaeffeler, Elke, Burghaus, Rolf, Yilmaz, Ali, Blank, Lars Mathias, Kerb, Reinhold, Lippert, Jörg, Schlender, Jan‐Frederik, Schwab, Matthias, Kuepfer, Lars
Published in CPT: pharmacometrics and systems pharmacology (01.07.2021)
Published in CPT: pharmacometrics and systems pharmacology (01.07.2021)
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Development of a Multi-Purpose Comprehensive Physiologically Based Pharmacokinetic Model for Crizotinib: An Example Application in Bioequivalence Assessment between Oral Solution and Granules in Pediatric Subjects
Sagawa, Kazuko, Purohit, Vivek, Le, Vu, Hsu, Hao-Jui, Ebrahimi, Eddie, Piscitelli, Joseph, Xu, Huiping, Johnson, Theodore
Published in The AAPS journal (28.07.2025)
Published in The AAPS journal (28.07.2025)
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