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Polymerized human hemoglobin with low and high oxygen affinity in trauma models
Muller, Cynthia R., Courelli, Vasiliki, Walser, Cynthia, Cuddington, Clayton T., Wolfe, Savannah R., Palmer, Andre F., Cabrales, Pedro
Published in Translational research : the journal of laboratory and clinical medicine (01.10.2023)
Published in Translational research : the journal of laboratory and clinical medicine (01.10.2023)
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Journal Article
Hb Waikato [α127(H10)Lys→Gln; HBA1 : c.382A>C]: A Novel High Oxygen Affinity Variant
Moore, Jordyn A., Pullon, Beverley M., Wang, Darrell, Brennan, Stephen O.
Published in Hemoglobin (02.01.2021)
Published in Hemoglobin (02.01.2021)
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Journal Article
Hemoglobin Oxygen Affinity in Patients with Cystic Fibrosis
Böning, Dieter, Littschwager, Angela, Hütler, Matthias, Beneke, Ralph, Staab, Doris
Published in PloS one (11.06.2014)
Published in PloS one (11.06.2014)
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Journal Article
High altitude genetic adaptation in Tibetans: No role of increased hemoglobin–oxygen affinity
Tashi, Tsewang, Feng, Tang, Koul, Parvaiz, Amaru, Ricardo, Hussey, Dottie, Lorenzo, Felipe R., RiLi, Ge, Prchal, Josef T.
Published in Blood cells, molecules, & diseases (01.06.2014)
Published in Blood cells, molecules, & diseases (01.06.2014)
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Journal Article
Mitapivat (AG-348) Demonstrates Safety, Tolerability, and Improvements in Anemia, Hemolysis, Oxygen Affinity, and Hemoglobin S Polymerization Kinetics in Adults with Sickle Cell Disease: A Phase 1 Dose Escalation Study
Xu, Julia Z., Conrey, Anna, Frey, Ingrid, Gwaabe, Eveline, Menapace, Laurel A, Tumburu, Laxminath, Lundt, Maureen, Li, Quan, Glass, Kristen, Iyer, Varsha, Mangus, Heidi, Kung, Charles, Dang, Lenny, Kosinski, Penelope A., Hawkins, Peter, Jeffries, Neal, Eaton, William, Thein, Swee Lay
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
A new β-chain haemoglobin variant with increased oxygen affinity: Hb Roma [β115(g17)Ala → Val]
Manconi, Barbara, De Rosa, Maria Cristina, Cappabianca, Maria Pia, Olianas, Alessandra, Alinovi, Cristiana Carelli, Mastropietro, Fabrizio, Ponzini, Donatella, Amato, Antonio, Pellegrini, Mariagiuseppina
Published in Biochimica et biophysica acta (01.03.2010)
Published in Biochimica et biophysica acta (01.03.2010)
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Journal Article
PP-14, a Novel Structurally-Enhanced Antisickling Allosteric Hemoglobin Effector, Increases Oxygen Affinity and Disrupts Hemoglobin S Polymer Formation
Safo, Martin K., Pagare, Piyusha P, Ghatge, Mohini, Casu, Carla, Ghiaccio, Valentina, Anabaraonye, Nancy, Xu, Xiaomeng, Rivella, Stefano, Hines, Patrick C., Liu, Ke, Zhang, Yan, Venitz, Jürgen, Abdulmalik, Osheiza
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Hb Waikato α127(H10)Lys→Gln; HBA1: c.382A>C: A Novel High Oxygen Affinity Variant
Moore, Jordyn A, Pullon, Beverley M, Wang, Darrell, Brennan, Stephen O
Published in Hemoglobin (01.01.2021)
Published in Hemoglobin (01.01.2021)
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Journal Article
Investigation of the Molecular Basis of High Oxygen Affinity Hemoglobin Brigham (α2Aβ2100 Pro→Leu) In a Subject with Familial Erythrocytosis
Abraham, Bindu, Jia, Yiping, Wood, Francine, Reiter, Chad, Lozier, Jay Nelson, Miller, Jeffery L., Alayash, Abdu
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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Journal Article
A Phase 1, First-in-Man, Dose-Response Study of Aes-103 (5-HMF), an Anti-Sickling, Allosteric Modifier of Hemoglobin Oxygen Affinity in Healthy Norman Volunteers
Stern, Warren, Mathews, David, McKew, John, Shen, Xiqgiang, Kato, Gregory J.
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
Effect of Aes-103 Anti-Sickling Agent On Oxygen Affinity and Stability of Red Blood Cells From Patients with Sickle Cell Anemia
Mendelsohn, Laurel G., Pedoeim, Leah, van Beers, Eduard J., Saiyed, Rehan, Nichols, James S, Wang, Xunde, Kato, Gregory J.
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
The antisickling agent, 5‐hydroxymethyl‐2‐furfural: Other potential pharmacological applications
Pagare, Piyusha P., McGinn, Mina, Ghatge, Mohini S., Shekhar, Vibha, Alhashimi, Rana T., Daniel Pierce, B., Abdulmalik, Osheiza, Zhang, Yan, Safo, Martin K.
Published in Medicinal research reviews (01.11.2024)
Published in Medicinal research reviews (01.11.2024)
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Journal Article
Low concentrations of nitric oxide increase oxygen affinity of sickle erythrocytes in vitro and in vivo
Head, C A, Brugnara, C, Martinez-Ruiz, R, Kacmarek, R M, Bridges, K R, Kuter, D, Bloch, K D, Zapol, W M
Published in The Journal of clinical investigation (01.09.1997)
Published in The Journal of clinical investigation (01.09.1997)
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Journal Article
Effects of an allosteric hemoglobin affinity modulator on arterial blood gases and cardiopulmonary responses during normoxic and hypoxic low-intensity exercise
Stewart, Glenn M., Chase, Steven, Cross, Troy J., Wheatley-Guy, Courtney M., Joyner, Michael J., Curry, Timothy, Lehrer-Graiwer, Josh, Dufu, Kobina, Vlahakis, Nicholas E., Johnson, Bruce D.
Published in Journal of applied physiology (1985) (01.06.2020)
Published in Journal of applied physiology (1985) (01.06.2020)
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Journal Article
The oxygen dissociation curve of blood in COVID-19–An update
Böning, Dieter, Kuebler, Wolfgang M., Vogel, Dominik, Bloch, Wilhelm
Published in Frontiers in medicine (27.02.2023)
Published in Frontiers in medicine (27.02.2023)
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Journal Article
Muscle oxygenation during normoxic and hypoxic cycling exercise in humans with high‐affinity haemoglobin
Webb, Kevin L., Elshaer, Ahmed N., Dominelli, Paolo B., Senefeld, Jonathon W., Hammer, Shane M., Baker, Sarah E., Shepherd, John R. A., Roy, Tuhin K., Joyner, Michael J., Wiggins, Chad C.
Published in Experimental physiology (01.08.2022)
Published in Experimental physiology (01.08.2022)
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Journal Article