Post-translational modification: nature's escape from genetic imprisonment and the basis for dynamic information encoding
Prabakaran, Sudhakaran, Lippens, Guy, Steen, Hanno, Gunawardena, Jeremy
Published in Wiley interdisciplinary reviews. Systems biology and medicine (01.11.2012)
Published in Wiley interdisciplinary reviews. Systems biology and medicine (01.11.2012)
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Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma
Verstraete, Kenneth, Peelman, Frank, Braun, Harald, Lopez, Juan, Van Rompaey, Dries, Dansercoer, Ann, Vandenberghe, Isabel, Pauwels, Kris, Tavernier, Jan, Lambrecht, Bart N., Hammad, Hamida, De Winter, Hans, Beyaert, Rudi, Lippens, Guy, Savvides, Savvas N.
Published in Nature communications (03.04.2017)
Published in Nature communications (03.04.2017)
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Efficient Access to Deuterated and Tritiated Nucleobase Pharmaceuticals and Oligonucleotides using Hydrogen‐Isotope Exchange
Palazzolo, Alberto, Feuillastre, Sophie, Pfeifer, Viktor, Garcia‐Argote, Sébastien, Bouzouita, Donia, Tricard, Simon, Chollet, Céline, Marcon, Elodie, Buisson, David‐Alexandre, Cholet, Sophie, Fenaille, François, Lippens, Guy, Chaudret, Bruno, Pieters, Grégory
Published in Angewandte Chemie International Edition (01.04.2019)
Published in Angewandte Chemie International Edition (01.04.2019)
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Efficient in vivo synthesis of lasso peptide pseudomycoidin proceeds in the absence of both the leader and the leader peptidase
Zyubko, Tatyana, Serebryakova, Marina, Andreeva, Julia, Metelev, Mikhail, Lippens, Guy, Dubiley, Svetlana, Severinov, Konstantin
Published in Chemical science (Cambridge) (2019)
Published in Chemical science (Cambridge) (2019)
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Fluorescent BODIPY-Based Zn(II) Complex as a Molecular Probe for Selective Detection of Neurofibrillary Tangles in the Brains of Alzheimer’s Disease Patients
Ojida, Akio, Sakamoto, Takashi, Inoue, Masa-aki, Fujishima, Sho-hei, Lippens, Guy, Hamachi, Itaru
Published in Journal of the American Chemical Society (13.05.2009)
Published in Journal of the American Chemical Society (13.05.2009)
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Journal Article
Cell signaling, post-translational protein modifications and NMR spectroscopy
Theillet, Francois-Xavier, Smet-Nocca, Caroline, Liokatis, Stamatios, Thongwichian, Rossukon, Kosten, Jonas, Yoon, Mi-Kyung, Kriwacki, Richard W., Landrieu, Isabelle, Lippens, Guy, Selenko, Philipp
Published in Journal of biomolecular NMR (01.11.2012)
Published in Journal of biomolecular NMR (01.11.2012)
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DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A
Coelmont, Lotte, Hanoulle, Xavier, Chatterji, Udayan, Berger, Carola, Snoeck, Joke, Bobardt, Michael, Lim, Precious, Vliegen, Inge, Paeshuyse, Jan, Vuagniaux, Grégoire, Vandamme, Anne-Mieke, Bartenschlager, Ralf, Gallay, Philippe, Lippens, Guy, Neyts, Johan
Published in PloS one (27.10.2010)
Published in PloS one (27.10.2010)
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Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice
Borghgraef, Peter, Menuet, Clément, Theunis, Clara, Louis, Justin V, Devijver, Herman, Maurin, Hervé, Smet-Nocca, Caroline, Lippens, Guy, Hilaire, Gerard, Gijsen, Harrie, Moechars, Dieder, Van Leuven, Fred
Published in PloS one (23.12.2013)
Published in PloS one (23.12.2013)
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Studying Intrinsically Disordered Proteins under True In Vivo Conditions by Combined Cross-Polarization and Carbonyl-Detection NMR Spectroscopy
Lopez, Juan, Schneider, Robert, Cantrelle, Francois-Xavier, Huvent, Isabelle, Lippens, Guy
Published in Angewandte Chemie International Edition (20.06.2016)
Published in Angewandte Chemie International Edition (20.06.2016)
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Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice
Deprez-Poulain, Rebecca, Hennuyer, Nathalie, Bosc, Damien, Liang, Wenguang G., Enée, Emmanuelle, Marechal, Xavier, Charton, Julie, Totobenazara, Jane, Berte, Gonzague, Jahklal, Jouda, Verdelet, Tristan, Dumont, Julie, Dassonneville, Sandrine, Woitrain, Eloise, Gauriot, Marion, Paquet, Charlotte, Duplan, Isabelle, Hermant, Paul, Cantrelle, François- Xavier, Sevin, Emmanuel, Culot, Maxime, Landry, Valerie, Herledan, Adrien, Piveteau, Catherine, Lippens, Guy, Leroux, Florence, Tang, Wei-Jen, van Endert, Peter, Staels, Bart, Deprez, Benoit
Published in Nature communications (23.09.2015)
Published in Nature communications (23.09.2015)
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Hepatitis C Virus NS5A Protein Is a Substrate for the Peptidyl-prolyl cis/trans Isomerase Activity of Cyclophilins A and B
Hanoulle, Xavier, Badillo, Aurélie, Wieruszeski, Jean-Michel, Verdegem, Dries, Landrieu, Isabelle, Bartenschlager, Ralf, Penin, François, Lippens, Guy
Published in The Journal of biological chemistry (15.05.2009)
Published in The Journal of biological chemistry (15.05.2009)
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Characterization of a Family of Scorpion Toxins Modulating Ca2+-Activated Cl− Current in Vascular Myocytes
Morel, Jean-Luc, Mokrzycki, Nathalie, Lippens, Guy, Drobecq, Hervé, Sautière, Pierre, Hugues, Michel
Published in Toxins (10.11.2022)
Published in Toxins (10.11.2022)
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Journal Article
Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy
Giustiniani, Julien, Chambraud, Béatrice, Sardin, Elodie, Dounane, Omar, Guillemeau, Kevin, Nakatani, Hiroko, Paquet, Dominik, Kamah, Amina, Landrieu, Isabelle, Lippens, Guy, Baulieu, Etienne-Emile, Tawk, Marcel
Published in Proceedings of the National Academy of Sciences - PNAS (25.03.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (25.03.2014)
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Characterization of the AT180 epitope of phosphorylated Tau protein by a combined nuclear magnetic resonance and fluorescence spectroscopy approach
Amniai, Laziza, Lippens, Guy, Landrieu, Isabelle
Published in Biochemical and biophysical research communications (09.09.2011)
Published in Biochemical and biophysical research communications (09.09.2011)
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Mice lacking phosphatase PP2A subunit PR61/B'δ (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3β
Louis, Justin V., Martens, Ellen, Borghgraef, Peter, Lambrecht, Caroline, Sents, Ward, Longin, Sari, Zwaenepoel, Karen, Pijnenborg, Robert, Landrieu, Isabelle, Lippens, Guy, Ledermann, Birgit, Götz, Jürgen, Van Leuven, Fred, Goris, Jozef, Janssens, Veerle, Südhof, Thomas C.
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.2011)
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Systematic Identification of Tubulin-interacting Fragments of the Microtubule-associated Protein Tau Leads to a Highly Efficient Promoter of Microtubule Assembly
Fauquant, Caroline, Redeker, Virginie, Landrieu, Isabelle, Wieruszeski, Jean-Michel, Verdegem, Dries, Laprévote, Olivier, Lippens, Guy, Gigant, Benoît, Knossow, Marcel
Published in The Journal of biological chemistry (23.09.2011)
Published in The Journal of biological chemistry (23.09.2011)
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Journal Article
Overall Structural Model of NS5A Protein from Hepatitis C Virus and Modulation by Mutations Confering Resistance of Virus Replication to Cyclosporin A
Badillo, Aurelie, Receveur-Brechot, Véronique, Sarrazin, Stéphane, Cantrelle, François-Xavier, Delolme, Frédéric, Fogeron, Marie-Laure, Molle, Jennifer, Montserret, Roland, Bockmann, Anja, Bartenschlager, Ralf, Lohmann, Volker, Lippens, Guy, Ricard-Blum, Sylvie, Hanoulle, Xavier, Penin, François
Published in Biochemistry (Easton) (20.06.2017)
Published in Biochemistry (Easton) (20.06.2017)
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Journal Article
A Proline-Tryptophan Turn in the Intrinsically Disordered Domain 2 of NS5A Protein Is Essential for Hepatitis C Virus RNA Replication
Dujardin, Marie, Madan, Vanesa, Montserret, Roland, Ahuja, Puneet, Huvent, Isabelle, Launay, Helene, Leroy, Arnaud, Bartenschlager, Ralf, Penin, François, Lippens, Guy, Hanoulle, Xavier
Published in The Journal of biological chemistry (31.07.2015)
Published in The Journal of biological chemistry (31.07.2015)
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Journal Article
Hepatitis C Virus NS5B and Host Cyclophilin A Share a Common Binding Site on NS5A
Rosnoblet, Claire, Fritzinger, Bernd, Legrand, Dominique, Launay, Hélène, Wieruszeski, Jean-Michel, Lippens, Guy, Hanoulle, Xavier
Published in The Journal of biological chemistry (28.12.2012)
Published in The Journal of biological chemistry (28.12.2012)
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Journal Article
Molecular implication of PP2A and Pin1 in the Alzheimer's disease specific hyperphosphorylation of Tau
Landrieu, Isabelle, Smet-Nocca, Caroline, Amniai, Laziza, Louis, Justin Vijay, Wieruszeski, Jean-Michel, Goris, Jozef, Janssens, Veerle, Lippens, Guy
Published in PloS one (23.06.2011)
Published in PloS one (23.06.2011)
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