Lenvatinib exhibits antineoplastic activity in anaplastic thyroid cancer in vitro and in vivo
Ferrari, Silvia Martina, Bocci, Guido, Di Desidero, Teresa, Elia, Giusy, Ruffilli, Ilaria, Ragusa, Francesca, Orlandi, Paola, Paparo, Sabrina Rosaria, Patrizio, Armando, Piaggi, Simona, La Motta, Concettina, Ulisse, Salvatore, Baldini, Enke, Materazzi, Gabriele, Miccoli, Paolo, Antonelli, Alessandro, Fallahi, Poupak
Published in Oncology reports (01.05.2018)
Published in Oncology reports (01.05.2018)
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Preclinical Development of FA5, a Novel AMP-Activated Protein Kinase (AMPK) Activator as an Innovative Drug for the Management of Bowel Inflammation
Antonioli, Luca, Pellegrini, Carolina, Fornai, Matteo, Benvenuti, Laura, D'Antongiovanni, Vanessa, Colucci, Rocchina, Bertani, Lorenzo, Di Salvo, Clelia, Semeghini, Giorgia, La Motta, Concettina, Giusti, Laura, Zallocco, Lorenzo, Ronci, Maurizio, Quattrini, Luca, Angelucci, Francesco, Coviello, Vito, Oh, Won-Keun, Ha, Quy Thi Kim, Németh, Zoltan H, Haskó, Gyorgy, Blandizzi, Corrado
Published in International journal of molecular sciences (13.06.2021)
Published in International journal of molecular sciences (13.06.2021)
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Antineoplastic Effect of Lenvatinib and Vandetanib in Primary Anaplastic Thyroid Cancer Cells Obtained From Biopsy or Fine Needle Aspiration
Ferrari, Silvia Martina, La Motta, Concettina, Elia, Giusy, Ragusa, Francesca, Ruffilli, Ilaria, Quattrini, Luca, Paparo, Sabrina Rosaria, Piaggi, Simona, Patrizio, Armando, Ulisse, Salvatore, Baldini, Enke, Materazzi, Gabriele, Fallahi, Poupak, Antonelli, Alessandro
Published in Frontiers in endocrinology (Lausanne) (18.12.2018)
Published in Frontiers in endocrinology (Lausanne) (18.12.2018)
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Exploiting the Pyrazolo[3,4-d]pyrimidin-4-one Ring System as a Useful Template To Obtain Potent Adenosine Deaminase Inhibitors
La Motta, Concettina, Sartini, Stefania, Mugnaini, Laura, Salerno, Silvia, Simorini, Francesca, Taliani, Sabrina, Marini, Anna Maria, Da Settimo, Federico, Lavecchia, Antonio, Novellino, Ettore, Antonioli, Luca, Fornai, Matteo, Blandizzi, Corrado, Del Tacca, Mario
Published in Journal of medicinal chemistry (26.03.2009)
Published in Journal of medicinal chemistry (26.03.2009)
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Pyrido[1,2-a]pyrimidin-4-one Derivatives as a Novel Class of Selective Aldose Reductase Inhibitors Exhibiting Antioxidant Activity
La Motta, Concettina, Sartini, Stefania, Mugnaini, Laura, Simorini, Francesca, Taliani, Sabrina, Salerno, Silvia, Marini, Anna Maria, Da Settimo, Federico, Lavecchia, Antonio, Novellino, Ettore, Cantore, Miriam, Failli, Paola, Ciuffi, Mario
Published in Journal of medicinal chemistry (04.10.2007)
Published in Journal of medicinal chemistry (04.10.2007)
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FOXD1-ALDH1A3 Signaling Is a Determinant for the Self-Renewal and Tumorigenicity of Mesenchymal Glioma Stem Cells
Cheng, Peng, Wang, Jia, Waghmare, Indrayani, Sartini, Stefania, Coviello, Vito, Zhang, Zhuo, Kim, Sung-Hak, Mohyeldin, Ahmed, Pavlyukov, Marat S, Minata, Mutsuko, Valentim, Claudia L L, Chhipa, Rishi Raj, Bhat, Krishna P L, Dasgupta, Biplab, La Motta, Concettina, Kango-Singh, Madhuri, Nakano, Ichiro
Published in Cancer research (Chicago, Ill.) (15.12.2016)
Published in Cancer research (Chicago, Ill.) (15.12.2016)
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Sampling protein motion and solvent effect during ligand binding
Limongelli, Vittorio, Marinelli, Luciana, Cosconati, Sandro, La Motta, Concettina, Sartini, Stefania, Mugnaini, Laura, Da Settimo, Federico, Novellino, Ettore, Parrinello, Michele
Published in Proceedings of the National Academy of Sciences - PNAS (31.01.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (31.01.2012)
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Identification of ALDH1A3 as a Viable Therapeutic Target in Breast Cancer Metastasis-Initiating Cells
Yamashita, Daisuke, Minata, Mutsuko, Ibrahim, Ahmed N, Yamaguchi, Shinobu, Coviello, Vito, Bernstock, Joshua D, Harada, Shuko, Cerione, Richard A, Tannous, Bakhos A, La Motta, Concettina, Nakano, Ichiro
Published in Molecular cancer therapeutics (01.05.2020)
Published in Molecular cancer therapeutics (01.05.2020)
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Adenosine deaminase in the modulation of immune system and its potential as a novel target for treatment of inflammatory disorders
Antonioli, Luca, Colucci, Rocchina, La Motta, Concettina, Tuccori, Marco, Awwad, Oriana, Da Settimo, Federico, Blandizzi, Corrado, Fornai, Matteo
Published in Current drug targets (01.06.2012)
Published in Current drug targets (01.06.2012)
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Antineoplastic Effect of ALK Inhibitor Crizotinib in Primary Human Anaplastic Thyroid Cancer Cells with STRN–ALK Fusion In Vitro
Ferrari, Silvia Martina, Ragusa, Francesca, Elia, Giusy, Mazzi, Valeria, Balestri, Eugenia, Botrini, Chiara, Rugani, Licia, Patrizio, Armando, Piaggi, Simona, La Motta, Concettina, Ulisse, Salvatore, Virili, Camilla, Antonelli, Alessandro, Fallahi, Poupak
Published in International journal of molecular sciences (01.06.2024)
Published in International journal of molecular sciences (01.06.2024)
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A Selective ALDH1A3 Inhibitor Impairs Mesothelioma 3-D Multicellular Spheroid Growth and Neutrophil Recruitment
Boumya, Sara, Fallarini, Silvia, Siragusa, Sonia, Petrarolo, Giovanni, Aprile, Silvio, Audrito, Valentina, La Motta, Concettina, Garavaglia, Silvia, Moro, Laura, Pinton, Giulia
Published in International journal of molecular sciences (01.04.2023)
Published in International journal of molecular sciences (01.04.2023)
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Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1,5-diarylpyrrol-3-substituted scaffold
Reale, Annalisa, Brogi, Simone, Chelini, Alessia, Paolino, Marco, Di Capua, Angela, Giuliani, Germano, Cappelli, Andrea, Giorgi, Gianluca, Chemi, Giulia, Grillo, Alessandro, Valoti, Massimo, Sautebin, Lidia, Rossi, Antonietta, Pace, Simona, La Motta, Concettina, Di Cesare Mannelli, Lorenzo, Lucarini, Elena, Ghelardini, Carla, Anzini, Maurizio
Published in Bioorganic & medicinal chemistry (01.10.2019)
Published in Bioorganic & medicinal chemistry (01.10.2019)
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A Selective Competitive Inhibitor of Aldehyde Dehydrogenase 1A3 Hinders Cancer Cell Growth, Invasiveness and Stemness In Vitro
Gelardi, Edoardo L M, Colombo, Giorgia, Picarazzi, Francesca, Ferraris, Davide M, Mangione, Andrea, Petrarolo, Giovanni, Aronica, Eleonora, Rizzi, Menico, Mori, Mattia, La Motta, Concettina, Garavaglia, Silvia
Published in Cancers (19.01.2021)
Published in Cancers (19.01.2021)
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Complexing the Marine Sesquiterpene Euplotin C by Means of Cyclodextrin-Based Nanosponges: A Preliminary Investigation
Bertoli, Alessandra, LoBue, Anthea, Quattrini, Luca, Sartini, Stefania, Polini, Beatrice, Carpi, Sara, Frontini, Francesco Paolo, Di Giuseppe, Graziano, Guella, Graziano, Nieri, Paola, La Motta, Concettina
Published in Marine drugs (29.10.2022)
Published in Marine drugs (29.10.2022)
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A New Vista of Aldehyde Dehydrogenase 1A3 (ALDH1A3): New Specific Inhibitors and Activity-Based Probes Targeting ALDH1A3 Dependent Pathways in Glioblastoma, Mesothelioma and Other Cancers
Magrassi, Lorenzo, Pinton, Giulia, Luzzi, Sabino, Comincini, Sergio, Scravaglieri, Andrea, Gigliotti, Valentina, Bernardoni, Bianca Laura, D’Agostino, Ilaria, Juretich, Francesca, La Motta, Concettina, Garavaglia, Silvia
Published in Cancers (28.06.2024)
Published in Cancers (28.06.2024)
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Vandetanib has antineoplastic activity in anaplastic thyroid cancer, in vitro and in vivo
Ferrari, Silvia Martina, Bocci, Guido, Di Desidero, Teresa, Ruffilli, Ilaria, Elia, Giusy, Ragusa, Francesca, Fioravanti, Anna, Orlandi, Paola, Paparo, Sabrina Rosaria, Patrizio, Armando, Piaggi, Simona, La Motta, Concettina, Ulisse, Salvatore, Baldini, Enke, Materazzi, Gabriele, Miccoli, Paolo, Antonelli, Alessandro, Fallahi, Poupak
Published in Oncology reports (01.05.2018)
Published in Oncology reports (01.05.2018)
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Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII
Barresi, Elisabetta, Salerno, Silvia, Marini, Anna Maria, Taliani, Sabrina, La Motta, Concettina, Simorini, Francesca, Da Settimo, Federico, Vullo, Daniela, Supuran, Claudiu T.
Published in Bioorganic & medicinal chemistry (15.02.2016)
Published in Bioorganic & medicinal chemistry (15.02.2016)
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