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Mass balance, pharmacokinetics and pharmacodynamics of intravenous HSK3486, a novel anaesthetic, administered to healthy subjects
Bian, Yicong, Zhang, Hua, Ma, Sheng, Jiao, Yongyi, Yan, Pangke, Liu, Xiao, Ma, Shiping, Xiong, Yating, Gu, Zheming, Yu, Zhenwen, Huang, Chenrong, Miao, Liyan
Published in British journal of clinical pharmacology (01.01.2021)
Published in British journal of clinical pharmacology (01.01.2021)
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An Open‐Label, Multicenter, Phase I, Dose Escalation Study with Phase II Expansion Cohort to Determine the Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Intravenous TKM‐080301 in Subjects with Advanced Hepatocellular Carcinoma
El Dika, Imane, Lim, Ho Yeong, Yong, Wei Peng, Lin, Chia‐Chi, Yoon, Jung‐Hwan, Modiano, Manuel, Freilich, Bradley, Choi, Hye Jin, Chao, Tsu‐Yi, Kelley, Robin K., Brown, Joanne, Knox, Jennifer, Ryoo, Baek‐Yeol, Yau, Thomas, Abou‐Alfa, Ghassan K.
Published in The oncologist (Dayton, Ohio) (01.06.2019)
Published in The oncologist (Dayton, Ohio) (01.06.2019)
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Metabolism, Excretion, and Pharmacokinetics of [14C]‐Cefiderocol (S‐649266), a Siderophore Cephalosporin, in Healthy Subjects Following Intravenous Administration
Miyazaki, Shiro, Katsube, Takayuki, Shen, Helen, Tomek, Charles, Narukawa, Yukitoshi
Published in Journal of clinical pharmacology (01.07.2019)
Published in Journal of clinical pharmacology (01.07.2019)
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8-Plex quantitation of changes in cerebrospinal fluid protein expression in subjects undergoing intravenous immunoglobulin treatment for Alzheimer's disease
Choe, Leila, D'Ascenzo, Mark, Relkin, Norman R, Pappin, Darryl, Ross, Philip, Williamson, Brian, Guertin, Steven, Pribil, Patrick, Lee, Kelvin H
Published in Proteomics (Weinheim) (01.10.2007)
Published in Proteomics (Weinheim) (01.10.2007)
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Pharmacokinetics, Disposition, and Biotransformation of [14C]Omecamtiv Mecarbil in Healthy Male Subjects after a Single Intravenous or Oral Dose
Trivedi, Ashit, Wahlstrom, Jan, Mackowski, Mia, Dutta, Sandeep, Lee, Edward
Published in Drug metabolism and disposition (01.08.2021)
Published in Drug metabolism and disposition (01.08.2021)
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Is there enough naloxone to deter the diversion? Effect of concurrent administration of intravenous naloxone on opioid agonist effects of intravenous buprenorphine: A randomised, double‐blind, within‐subject, crossover study among opioid‐dependent subjects
Dhagudu, Naveen K., Ambekar, Atul, Agrawal, Alok, Rao, Ravindra, Mishra, Ashwani K., Jain, Raka, Singh, Shalini
Published in Drug and alcohol review (01.07.2020)
Published in Drug and alcohol review (01.07.2020)
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Pharmacokinetics, Metabolism, and Excretion of Intravenous [14C]Difelikefalin in Healthy Subjects and Subjects on Hemodialysis
Stark, Jeffrey G., Noonan, Patrick K., Spencer, Robert H., Bhaduri, Sarbani, O’Connor, Stephen J., Menzaghi, Frédérique
Published in Clinical pharmacokinetics (01.09.2023)
Published in Clinical pharmacokinetics (01.09.2023)
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Randomized, Double‐Blind, Placebo‐Controlled, Dose‐Escalating Phase I, Healthy Subjects Study of Intravenous OPN‐305, a Humanized Anti‐TLR2 Antibody
Reilly, M, Miller, R M, Thomson, M H, Patris, V, Ryle, P, McLoughlin, L, Mutch, P, Gilboy, P, Miller, C, Broekema, M, Keogh, B, McCormack, W, Wetering de Rooij, J
Published in Clinical pharmacology and therapeutics (01.11.2013)
Published in Clinical pharmacology and therapeutics (01.11.2013)
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Pharmacokinetics, Safety, and Tolerability of Intravenous Durlobactam and Sulbactam in Subjects with Renal Impairment and Healthy Matched Control Subjects
O’Donnell, John, Preston, Richard A., Mamikonyan, Grigor, Stone, Emily, Isaacs, Robin
Published in Antimicrobial agents and chemotherapy (01.09.2019)
Published in Antimicrobial agents and chemotherapy (01.09.2019)
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Safety, Tolerability, Pharmacokinetics, and Drug Interaction Potential of SPR741, an Intravenous Potentiator, after Single and Multiple Ascending Doses and When Combined with β-Lactam Antibiotics in Healthy Subjects
Eckburg, Paul B., Lister, Troy, Walpole, Susannah, Keutzer, Tim, Utley, Luke, Tomayko, John, Kopp, Ellen, Farinola, Nicholas, Coleman, Scott
Published in Antimicrobial agents and chemotherapy (01.09.2019)
Published in Antimicrobial agents and chemotherapy (01.09.2019)
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Effect of Intravenous Ethanol on Capsaicin-Induced Hyperalgesia in Human Subjects
Arout, Caroline A., Perrino Jr, Albert C., Ralevski, Elizabeth, Acampora, Gregory, Koretski, Julia, Limoncelli, Diana, Newcomb, Jenelle, Petrakis, Ismene L.
Published in Alcoholism, clinical and experimental research (01.07.2016)
Published in Alcoholism, clinical and experimental research (01.07.2016)
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Bioequivalence study of voriconazole for intravenous infusion in healthy Chinese subjects under fasting conditions
Xiang, Zhangqiang, Li, Mupeng, Cui, Shaoting, Gan, Chunyan, Liu, Fangfang, Huang, Qian, Mai, Gang, Fan, Lianlian
Published in Journal of pharmaceutical sciences (01.02.2025)
Published in Journal of pharmaceutical sciences (01.02.2025)
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Pharmacokinetics and pharmacodynamics of intravenous delafloxacin in healthy subjects: model-based dose optimization
Lv, Jiong-Xian, Huang, Yi-Huan, Kafauit, Farah, Wang, Yuan-Hui, Su, Chang, Ma, Jun-Heng, Xu, Yan, Huang, Chao-Chao, Zhang, Qing, Su, Yu-Wen
Published in Antimicrobial agents and chemotherapy (09.07.2024)
Published in Antimicrobial agents and chemotherapy (09.07.2024)
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A Prospective, Randomized, Double-Blinded Study of the Effect of Intravenous Ondansetron on the Effective Dose in 50% of Subjects of Prophylactic Phenylephrine Infusions for Preventing Spinal Anesthesia–Induced Hypotension During Cesarean Delivery
Xiao, Fei, Wei, Changna, Chang, Xiangyang, Zhang, Yinfa, Xue, Lili, Shen, Huaxiang, Ngan Kee, Warwick D., Chen, Xinzhong
Published in Anesthesia and analgesia (01.08.2020)
Published in Anesthesia and analgesia (01.08.2020)
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Erratum for Yang et al., “A phase I study of the safety, tolerability, and pharmacokinetics of contezolid acefosamil after intravenous and oral administration in healthy Chinese subjects”
Yang, Haijing, Jin, Yi, Wang, Hailin, Yuan, Hong, Wang, Jingjing, Li, Size, Hu, Yingying, Yang, Huahui, Li, Xin, Liang, Hong, Wu, Jufang, Cao, Guoying, Zhang, Jing
Published in Antimicrobial agents and chemotherapy (08.10.2024)
Published in Antimicrobial agents and chemotherapy (08.10.2024)
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Randomised comparison of intravenous and subcutaneous routes of glucagon‐like peptide‐1 administration for lowering plasma glucose in hyperglycaemic subjects with type 2 diabetes
Quast, Daniel R., Lancaster, Dara, Xie, Cong, Bound, Michelle J., Grivell, Jacqueline, Jones, Karen L., Horowitz, Michael, Meier, Juris J., Wu, Tongzhi, Rayner, Christopher K., Nauck, Michael A.
Published in Diabetes, obesity & metabolism (01.09.2024)
Published in Diabetes, obesity & metabolism (01.09.2024)
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Pharmacokinetics and safety of colistin sulfate after single and multiple intravenous doses in healthy Chinese subjects
Huang, Xiaolan, Liu, Xiaofen, Fan, Yaxin, Wang, Yu, Guo, Beining, Wang, Jingjing, Yu, Jicheng, Wei, Qiong, Wu, Xiaojie, Huang, Haihui, Zhang, Jing
Published in International journal of antimicrobial agents (01.11.2024)
Published in International journal of antimicrobial agents (01.11.2024)
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Plasma and Intrapulmonary Concentrations of ETX2514 and Sulbactam following Intravenous Administration of ETX2514SUL to Healthy Adult Subjects
Rodvold, Keith A., Gotfried, Mark H., Isaacs, Robin D., O'Donnell, John P., Stone, Emily
Published in Antimicrobial agents and chemotherapy (01.11.2018)
Published in Antimicrobial agents and chemotherapy (01.11.2018)
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Acute toxicity is a dose-limiting factor for intravenous polymyxin B: A safety and pharmacokinetic study in healthy Chinese subjects
Liu, Xiaofen, Chen, Yuancheng, Yang, Haijing, Li, Jian, Yu, Jicheng, Yu, Zhenwei, Cao, Guoying, Wu, Xiaojie, Wang, Yu, Wu, Hailan, Fan, Yaxin, Wang, Jingjing, Wu, Jufang, Jin, Yi, Guo, Beining, Hu, Jiali, Bian, Xingchen, Li, Xin, Zhang, Jing
Published in The Journal of infection (01.02.2021)
Published in The Journal of infection (01.02.2021)
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