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Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease–like pathology and cognitive decline
vom Berg, Johannes, Prokop, Stefan, Miller, Kelly R, Obst, Juliane, Kälin, Roland E, Lopategui-Cabezas, Ileana, Wegner, Anja, Mair, Florian, Schipke, Carola G, Peters, Oliver, Winter, York, Becher, Burkhard, Heppner, Frank L
Published in Nature medicine (01.12.2012)
Published in Nature medicine (01.12.2012)
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Combined immunotherapy with controlled interleukin-12 gene therapy and immune checkpoint blockade in recurrent glioblastoma: An open-label, multi-institutional phase I trial
Chiocca, E Antonio, Gelb, Arnold B, Chen, Clark C, Rao, Ganesh, Reardon, David A, Wen, Patrick Y, Bi, Wenya Linda, Peruzzi, Pierpaolo, Amidei, Christina, Triggs, Dan, Seften, Leah, Park, Grace, Grant, James, Truman, Kyla, Buck, Jill Y, Hadar, Nira, Demars, Nathan, Miao, John, Estupinan, Taylor, Loewy, John, Chadha, Kamal, Tringali, Joseph, Cooper, Laurence, Lukas, Rimas V
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2022)
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Molecular profiling and gene expression analysis in cutaneous sarcoidosis: The role of interleukin-12, interleukin-23, and the T-helper 17 pathway
Judson, Marc A., Marchell, Richard M., Mascelli, MaryAnn, Piantone, Alexa, Barnathan, Elliot S., Petty, Kevin J., Chen, Dion, Fan, Hongtao, Grund, Heidi, Ma, Keying, Baribaud, Frédéric, Brodmerkel, Carrie
Published in Journal of the American Academy of Dermatology (01.06.2012)
Published in Journal of the American Academy of Dermatology (01.06.2012)
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Targeting HER-2/ neu in Early Breast Cancer Development Using Dendritic Cells with Staged Interleukin-12 Burst Secretion
Czerniecki, Brian J., Koski, Gary K., Koldovsky, Ursula, Xu, Shuwen, Cohen, Peter A., Mick, Rosemarie, Nisenbaum, Harvey, Pasha, Terry, Xu, Min, Fox, Kevin R., Weinstein, Susan, Orel, Susan G., Vonderheide, Robert, Coukos, George, DeMichele, Angela, Araujo, Louis, Spitz, Francis R., Rosen, Mark, Levine, Bruce L., June, Carl, Zhang, Paul J.
Published in Cancer research (Chicago, Ill.) (15.02.2007)
Published in Cancer research (Chicago, Ill.) (15.02.2007)
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A phase I clinical trial of oncolytic adenovirus mediated suicide and interleukin-12 gene therapy in patients with recurrent localized prostate adenocarcinoma
Nyati, Shyam, Stricker, Hans, Barton, Kenneth N., Li, Pin, Elshaikh, Mohamed, Ali, Haythem, Brown, Stephen L., Hwang, Clara, Peabody, James, Freytag, Svend O., Movsas, Benjamin, Siddiqui, Farzan
Published in PloS one (15.09.2023)
Published in PloS one (15.09.2023)
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First-in-Human Phase I Trial of a Tumor-Targeted Cytokine (NHS-IL12) in Subjects with Metastatic Solid Tumors
Strauss, Julius, Heery, Christopher R., Kim, Joseph W., Jochems, Caroline, Donahue, Renee N., Montgomery, Agnes S., McMahon, Sheri, Lamping, Elizabeth, Marté, Jennifer L., Madan, Ravi A., Bilusic, Marijo, Silver, Matthew R., Bertotti, Elisa, Schlom, Jeffrey, Gulley, James L.
Published in Clinical cancer research (01.01.2019)
Published in Clinical cancer research (01.01.2019)
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Increased serum levels of interleukin-12 and tumor necrosis factor-alpha in Tourette’s syndrome
Leckman, James F., Katsovich, Liliya, Kawikova, Ivana, Lin, Haiqun, Zhang, Heping, Krönig, Holger, Morshed, Syed, Parveen, Salina, Grantz, Heidi, Lombroso, Paul J., King, Robert A.
Published in Biological psychiatry (1969) (15.03.2005)
Published in Biological psychiatry (1969) (15.03.2005)
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Phase I trial of oncolytic adenovirus-mediated cytotoxic and interleukin-12 gene therapy for the treatment of metastatic pancreatic cancer
Barton, Kenneth N., Siddiqui, Farzan, Pompa, Robert, Freytag, Svend O., Khan, Gazala, Dobrosotskaya, Irina, Ajlouni, Munther, Zhang, Yingshu, Cheng, Jingfang, Movsas, Benjamin, Kwon, David
Published in Molecular therapy. Oncolytics (26.03.2021)
Published in Molecular therapy. Oncolytics (26.03.2021)
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Circulating interleukin-10 and interleukin-12 in Parkinson's disease
Rentzos, M., Nikolaou, C., Andreadou, E., Paraskevas, G. P., Rombos, A., Zoga, M., Tsoutsou, A., Boufidou, F., Kapaki, E., Vassilopoulos, D.
Published in Acta neurologica Scandinavica (01.05.2009)
Published in Acta neurologica Scandinavica (01.05.2009)
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Reduced cerebrospinal fluid concentration of interleukin-12/23 subunit p40 in patients with cognitive impairment
Johansson, Per, Almqvist, Erik G., Wallin, Anders, Johansson, Jan-Ove, Andreasson, Ulf, Blennow, Kaj, Zetterberg, Henrik, Svensson, Johan
Published in PloS one (02.05.2017)
Published in PloS one (02.05.2017)
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Serum levels of interleukin-10 and interleukin-12 predict early, spontaneous hepatitis B virus e antigen seroconversion
Wu, Jia-Feng, Wu, Tzee-Chung, Chen, Chien-Hung, Ni, Yen-Hsuan, Chen, Huey-Ling, Hsu, Hong-Yuan, Chang, Mei-Hwei
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2010)
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2010)
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Effect of interleukin‐12 gene expression on insulin resistance in patients with acne vulgaris
AbdElneam, Ahmed Ibrahim, Al‐Dhubaibi, Mohammed Saleh, Bahaj, Saleh Salem, Mohammed, Ghada Farouk, Alantry, Ahmed Kaid, Atef, Lina M.
Published in Skin research and technology (01.11.2023)
Published in Skin research and technology (01.11.2023)
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Lys-des[Arg 9 ]–Bradykinin Alters Migration and Production of Interleukin-12 in Monocyte-Derived Dendritic Cells
Gulliver, Rosalind, Baltic, Svetlana, Misso, Neil L., Bertram, Cornelia M., Thompson, Philip J., Fogel-Petrovic, Mirjana
Published in American journal of respiratory cell and molecular biology (01.09.2011)
Published in American journal of respiratory cell and molecular biology (01.09.2011)
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IL-12 receptor β1 deficiency alters in vivo T follicular helper cell response in humans
Schmitt, Nathalie, Bustamante, Jacinta, Bourdery, Laure, Bentebibel, Salah Eddine, Boisson-Dupuis, Stephanie, Hamlin, Fran, Tran, Mau V., Blankenship, Derek, Pascual, Virginia, Savino, Daniel A., Banchereau, Jacques, Casanova, Jean-Laurent, Ueno, Hideki
Published in Blood (25.04.2013)
Published in Blood (25.04.2013)
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PTU-002 Dendritic cell subsets and serum interleukin-12 are linked to renal injury in schistosomal hepatic fibrosis
Aggan, Hayam El, Salem, Mona, Gendy, Wessam El, Gebaly, Wageh El, Gohary, Eman El
Published in Gut (01.06.2019)
Published in Gut (01.06.2019)
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Interleukin-12p35 knockout promotes macrophage differentiation, aggravates vascular dysfunction, and elevates blood pressure in angiotensin II-infused mice
Ye, Jing, Que, Bin, Huang, Ying, Lin, Yingzhong, Chen, Jiangbin, Liu, Ling, Shi, Ying, Wang, Yuan, Wang, Menglong, Zeng, Tao, Wang, Zhen, Hu, Haiying, Xu, Yao, Shi, Lei, Ye, Di, Liu, Jianfang, Jiang, Huimin, Wan, Jun, Ji, Qingwei
Published in Cardiovascular research (01.05.2019)
Published in Cardiovascular research (01.05.2019)
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Frailty in Old Age Is Associated with Decreased Interleukin-12/23 Production in Response to Toll-Like Receptor Ligation
Compté, Nathalie, Zouaoui Boudjeltia, Karim, Vanhaeverbeek, Michel, De Breucker, Sandra, Tassignon, Joel, Trelcat, Anne, Pepersack, Thierry, Goriely, Stanislas
Published in PloS one (05.06.2013)
Published in PloS one (05.06.2013)
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Differential Regulation of Interleukin-12 (IL-12)/IL-23 by Tim-3 Drives TH17 Cell Development during Hepatitis C Virus Infection
Wang, Jia M., Shi, Lei, Ma, Cheng J., Ji, Xiao J., Ying, Ruo S., Wu, Xiao Y., Wang, Ke S., Li, Guangyu, Moorman, Jonathan P., Yao, Zhi Q.
Published in Journal of Virology (15.04.2013)
Published in Journal of Virology (15.04.2013)
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Interleukin-12 plasma levels in drug-naïve patients with a first episode of psychosis: Effects of antipsychotic drugs
Crespo-Facorro, Benedicto, Carrasco-Marín, Eugenio, Pérez-Iglesias, Rocío, Pelayo-Terán, José María, Fernandez-Prieto, Lorena, Leyva-Cobián, Francisco, Vázquez-Barquero, José Luis
Published in Psychiatry research (15.03.2008)
Published in Psychiatry research (15.03.2008)
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