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Increased Hepatic Synthesis and Dysregulation of Cholesterol Metabolism Is Associated with the Severity of Nonalcoholic Fatty Liver Disease
Min, Hae-Ki, Kapoor, Ashwani, Fuchs, Michael, Mirshahi, Faridoddin, Zhou, Huiping, Maher, James, Kellum, John, Warnick, Russell, Contos, Melissa J., Sanyal, Arun J.
Published in Cell metabolism (02.05.2012)
Published in Cell metabolism (02.05.2012)
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Longitudinal Course of Disease in a Large Cohort of Myositis Patients With Autoantibodies Recognizing the Signal Recognition Particle
Pinal‐Fernandez, Iago, Parks, Cassie, Werner, Jessie L., Albayda, Jemima, Paik, Julie J., Danoff, Sonye K., Casciola‐Rosen, Livia, Christopher‐Stine, Lisa, Mammen, Andrew L.
Published in Arthritis care & research (2010) (01.02.2017)
Published in Arthritis care & research (2010) (01.02.2017)
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The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase
Schumacher, Marc M, Elsabrouty, Rania, Seemann, Joachim, Jo, Youngah, DeBose-Boyd, Russell A
Published in eLife (05.03.2015)
Published in eLife (05.03.2015)
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The E3 Ubiquitin Ligase MARCH6 Degrades Squalene Monooxygenase and Affects 3-Hydroxy-3-Methyl-Glutaryl Coenzyme A Reductase and the Cholesterol Synthesis Pathway
Zelcer, Noam, Sharpe, Laura J., Loregger, Anke, Kristiana, Ika, Cook, Emma C. L., Phan, Lisa, Stevenson, Julian, Brown, Andrew J.
Published in Molecular and cellular biology (01.04.2014)
Published in Molecular and cellular biology (01.04.2014)
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Sterol synthesis pathway inhibition as a target for cancer treatment
Feltrin, Sara, Ravera, Francesco, Traversone, Noemi, Ferrando, Lorenzo, Bedognetti, Davide, Ballestrero, Alberto, Zoppoli, Gabriele
Published in Cancer letters (28.11.2020)
Published in Cancer letters (28.11.2020)
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Rarity of anti–3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase antibodies in statin users, including those with self‐limited musculoskeletal side effects
Mammen, Andrew L., Pak, Katherine, Williams, Emma K., Brisson, Diane, Coresh, Joe, Selvin, Elizabeth, Gaudet, Daniel
Published in Arthritis care & research (2010) (01.02.2012)
Published in Arthritis care & research (2010) (01.02.2012)
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Statin use in giant cell arteritis: a retrospective study
Schmidt, Jean, Kermani, Tanaz A, Muratore, Francesco, Crowson, Cynthia S, Matteson, Eric L, Warrington, Kenneth J
Published in Journal of rheumatology (01.06.2013)
Published in Journal of rheumatology (01.06.2013)
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Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis
Scholz, Markus, Horn, Katrin, Pott, Janne, Gross, Arnd, Kleber, Marcus E., Delgado, Graciela E., Mishra, Pashupati Prasad, Kirsten, Holger, Gieger, Christian, Müller-Nurasyid, Martina, Tönjes, Anke, Kovacs, Peter, Lehtimäki, Terho, Raitakari, Olli, Kähönen, Mika, Gylling, Helena, Baber, Ronny, Isermann, Berend, Stumvoll, Michael, Loeffler, Markus, März, Winfried, Meitinger, Thomas, Peters, Annette, Thiery, Joachim, Teupser, Daniel, Ceglarek, Uta
Published in Nature communications (10.01.2022)
Published in Nature communications (10.01.2022)
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Anti-HMGCR antibodies demonstrate high diagnostic value in the diagnosis of immune-mediated necrotizing myopathy following statin exposure
Shovman, O., Gilburd, B., Chayat, C., Lazar, A. Dortort, Amital, H., Blank, M., Bentow, C., Mahler, M., Shoenfeld, Y.
Published in Immunologic research (01.02.2017)
Published in Immunologic research (01.02.2017)
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Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis
Loregger, Anke, Raaben, Matthijs, Tan, Josephine, Scheij, Saskia, Moeton, Martina, van den Berg, Marlene, Gelberg-Etel, Hila, Stickel, Elmer, Roitelman, Joseph, Brummelkamp, Thijn, Zelcer, Noam
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2017)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2017)
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Coordinately Regulated Alternative Splicing of Genes Involved in Cholesterol Biosynthesis and Uptake
Medina, Marisa Wong, Gao, Feng, Naidoo, Devesh, Rudel, Lawrence L., Temel, Ryan E., McDaniel, Allison L., Marshall, Stephanie M., Krauss, Ronald M.
Published in PLoS ONE (29.04.2011)
Published in PLoS ONE (29.04.2011)
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Gestational diabetes mellitus modulates cholesterol homeostasis in human fetoplacental endothelium
Sun, Yidan, Kopp, Susanne, Strutz, Jasmin, Gali, Chaitanya Chakravarthi, Zandl-Lang, Martina, Fanaee-Danesh, Elham, Kirsch, Andrijana, Cvitic, Silvija, Frank, Saša, Saffery, Richard, Björkhem, Ingemar, Desoye, Gernot, Wadsack, Christian, Panzenboeck, Ute
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.09.2018)
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.09.2018)
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Thigh muscle MRI in immune-mediated necrotising myopathy: extensive oedema, early muscle damage and role of anti-SRP autoantibodies as a marker of severity
Pinal-Fernandez, Iago, Casal-Dominguez, Maria, Carrino, John A, Lahouti, Arash H, Basharat, Pari, Albayda, Jemima, Paik, Julie J, Ahlawat, Shivani, Danoff, Sonye K, Lloyd, Thomas E, Mammen, Andrew L, Christopher-Stine, Lisa
Published in Annals of the rheumatic diseases (01.04.2017)
Published in Annals of the rheumatic diseases (01.04.2017)
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Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system
Tsai, Yien Che, Leichner, Gil S., Pearce, Margaret M. P., Wilson, Gaye Lynn, Wojcikiewicz, Richard J. H., Roitelman, Joseph, Weissman, Allan M.
Published in Molecular biology of the cell (01.12.2012)
Published in Molecular biology of the cell (01.12.2012)
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Intake of Baked Cod Fillet Resulted in Lower Serum Cholesterol and Higher Long Chain n-3 PUFA Concentrations in Serum and Tissues in Hypercholesterolemic Obese Zucker fa/fa Rats
Vikøren, Linn A., Drotningsvik, Aslaug, Bergseth, Marthe T., Mjøs, Svein A., Austgulen, Maren H., Mellgren, Gunnar, Gudbrandsen, Oddrun A.
Published in Nutrients (28.06.2018)
Published in Nutrients (28.06.2018)
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Statin-associated autoimmune myopathy: A distinct new IFL pattern can increase the rate of HMGCR antibody detection by clinical laboratories
Alvarado-Cardenas, M., Marin-Sánchez, A., Martínez, M.A., Martínez-Martínez, L., Pinal-Fernandez, I., Labrador-Horrillo, M., Balada, E., Mundet-Tuduri, X., Gonzalez-Mera, L., Casademont, J., Acebes, E. Martínez, Moreno, P.J., Juarez, C., Grau-Junyent, J.M., Pujol-Borrell, R., Selva-O'Callaghan, A.
Published in Autoimmunity reviews (01.12.2016)
Published in Autoimmunity reviews (01.12.2016)
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Effect of HMGCR variant alleles on low-density lipoprotein cholesterol-lowering response to atorvastatin in healthy Korean subjects
Chung, Jae Yong, Cho, Sung Kweon, Oh, Eun Sil, Lee, Dong Hwan, Lim, Lay Ahyoung, Jang, Seong Bok, Lee, Yoon Jung, Park, Kyungsoo, Park, Min Soo
Published in Journal of clinical pharmacology (01.03.2012)
Published in Journal of clinical pharmacology (01.03.2012)
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Dysfunction of the Cholesterol Biosynthetic Pathway in Huntington's Disease
Valenza, Marta, Rigamonti, Dorotea, Goffredo, Donato, Zuccato, Chiara, Fenu, Simone, Jamot, Laure, Strand, Andrew, Tarditi, Alessia, Woodman, Ben, Racchi, Marco, Mariotti, Caterina, Di Donato, Stefano, Corsini, Alberto, Bates, Gillian, Pruss, Rebecca, Olson, James M, Sipione, Simonetta, Tartari, Marzia, Cattaneo, Elena
Published in The Journal of neuroscience (26.10.2005)
Published in The Journal of neuroscience (26.10.2005)
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