Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice
Murphy, Andrew J., Macdonald, Lynn E., Stevens, Sean, Karow, Margaret, Dore, Anthony T., Pobursky, Kevin, Huang, Tammy T., Poueymirou, William T., Esau, Lakeisha, Meola, Melissa, Mikulka, Warren, Krueger, Pamela, Fairhurst, Jeanette, Valenzuela, David M., Papadopoulos, Nicholas, Yancopoulos, George D.
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
Get full text
Journal Article
Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection
Pascal, Kristen E, Christopher M. Coleman, Alejandro O. Mujica, Vishal Kamat, Ashok Badithe, Jeanette Fairhurst, Charleen Hunt, John Strein, Alexander Berrebi, Jeanne M. Sisk, Krystal L. Matthews, Robert Babb, Gang Chen, Ka-Man V. Lai, Tammy T. Huang, William Olson, George D. Yancopoulos, Neil Stahl, Matthew B. Frieman, Christos A. Kyratsous
Published in Proceedings of the National Academy of Sciences - PNAS (14.07.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (14.07.2015)
Get full text
Journal Article
Breast Cancers Detected at Screening MR Imaging and Mammography in Patients at High Risk: Method of Detection Reflects Tumor Histopathologic Results
Sung, Janice S, Stamler, Sarah, Brooks, Jennifer, Kaplan, Jennifer, Huang, Tammy, Dershaw, D David, Lee, Carol H, Morris, Elizabeth A, Comstock, Christopher E
Published in Radiology (01.09.2016)
Published in Radiology (01.09.2016)
Get full text
Journal Article
Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates
Pascal, Kristen E, Dudgeon, Drew, Trefry, John C, Anantpadma, Manu, Sakurai, Yasuteru, Murin, Charles D, Turner, Hannah L, Fairhurst, Jeanette, Torres, Marcela, Rafique, Ashique, Yan, Ying, Badithe, Ashok, Yu, Kevin, Potocky, Terra, Bixler, Sandra L, Chance, Taylor B, Pratt, William D, Rossi, Franco D, Shamblin, Joshua D, Wollen, Suzanne E, Zelko, Justine M, Carrion, Jr, Ricardo, Worwa, Gabriella, Staples, Hilary M, Burakov, Darya, Babb, Robert, Chen, Gang, Martin, Joel, Huang, Tammy T, Erlandson, Karl, Willis, Melissa S, Armstrong, Kimberly, Dreier, Thomas M, Ward, Andrew B, Davey, Robert A, Pitt, Margaret L M, Lipsich, Leah, Mason, Peter, Olson, William, Stahl, Neil, Kyratsous, Christos A
Published in The Journal of Infectious Diseases (22.11.2018)
Published in The Journal of Infectious Diseases (22.11.2018)
Get full text
Journal Article
Web Resource
IL-33 blockade affects mediators of persistence and exacerbation in a model of chronic airway inflammation
Allinne, Jeanne, Scott, George, Lim, Wei Keat, Birchard, Dylan, Erjefält, Jonas S., Sandén, Caroline, Ben, Li-Hong, Agrawal, Amit, Kaur, Navneet, Kim, Jee Hae, Kamat, Vishal, Fury, Wen, Huang, Tammy, Stahl, Neil, Yancopoulos, George D., Murphy, Andrew J., Sleeman, Matthew A., Orengo, Jamie M.
Published in Journal of allergy and clinical immunology (01.12.2019)
Published in Journal of allergy and clinical immunology (01.12.2019)
Get full text
Journal Article
Inhibition of complement pathway activation with Pozelimab, a fully human antibody to complement component C5
Latuszek, Adrianna, Liu, Yashu, Olsen, Olav, Foster, Randi, Cao, Marc, Lovric, Irena, Yuan, Ming, Liu, Nina, Chen, Henry, Zhang, Qian, Xiao, Hui, Springer, Carola, Ehrlich, George, Kamat, Vishal, Rafique, Ashique, Hu, Ying, Krueger, Pamela, Huang, Tammy, Poueymirou, William, Babb, Robert, Rosconi, Michael P, Retter, Marc W, Chen, Gang, Morton, Lori, Zambrowicz, Brian, Cao, Jingtai, Romano, Carmelo, Olson, William C
Published in PloS one (08.05.2020)
Published in PloS one (08.05.2020)
Get full text
Journal Article
VEGF-Trap: A VEGF Blocker with Potent Antitumor Effects
Holash, Jocelyn, Davis, Sam, Papadopoulos, Nick, Croll, Susan D., Ho, Lillian, Russell, Michelle, Boland, Patricia, Leidich, Ray, Hylton, Donna, Burova, Elena, Ioffe, Ella, Huang, Tammy, Radziejewski, Czeslaw, Bailey, Kevin, Fandl, James P., Daly, Tom, Wiegand, Stanley J., Yancopoulos, George D., Rudge, John S.
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2002)
Get full text
Journal Article
ERBB3/HER2 signaling promotes resistance to EGFR blockade in head and neck and colorectal cancer models
Zhang, Li, Castanaro, Carla, Luan, Bo, Yang, Katie, Fan, Liangfen, Fairhurst, Jeanette L, Rafique, Ashique, Potocky, Terra B, Shan, Jing, Delfino, Frank J, Shi, Ergang, Huang, Tammy, Martin, Joel H, Chen, Gang, Macdonald, Douglas, Rudge, John S, Thurston, Gavin, Daly, Christopher
Published in Molecular cancer therapeutics (01.05.2014)
Published in Molecular cancer therapeutics (01.05.2014)
Get full text
Journal Article
Cytokine traps: multi-component, high-affinity blockers of cytokine action
Stahl, Neil, Economides, Aris N, Carpenter, Laura Rocco, Rudge, John S, Wong, Vivien, Koehler-Stec, Ellen M, Hartnett, Christopher, Pyles, Erica A, Xu, Xiaobing, Daly, Thomas J, Young, Michael R, Fandl, James P, Lee, Frank, Carver, Scott, McNay, Jennifer, Bailey, Kevin, Ramakanth, Swayampakula, Hutabarat, Renta, Huang, Tammy T, Radziejewski, Czeslaw, Yancopoulos, George D
Published in Nature medicine (01.01.2003)
Published in Nature medicine (01.01.2003)
Get full text
Journal Article
Enhanced IL-36R signaling promotes barrier impairment and inflammation in skin and intestine
Hovhannisyan, Zaruhi, Liu, Nengyin, Khalil-Aguero, Sara, Panea, Casandra, VanValkenburgh, Jeffrey, Zhang, Ruoyu, Lim, Wei Keat, Bai, Yu, Fury, Wen, Huang, Tammy, Garnova, Elena, Fairhurst, Jeanette, Kim, Jee, Aryal, Smita, Ajithdoss, Dharani, Oyejide, Adelekan, Del Pilar Molina-Portela, Maria, E, Hock, Poueymirou, William, Oristian, Nicole Stokes, Brydges, Susannah, Liu, Xia, Olson, William, Yancopoulos, George, Murphy, Andrew J, Sleeman, Matthew A, Haxhinasto, Sokol
Published in Science immunology (18.12.2020)
Published in Science immunology (18.12.2020)
Get more information
Journal Article
Noncuring Graphene Thermal Interface Materials for Advanced Electronics
Naghibi, Sahar, Kargar, Fariborz, Wright, Dylan, Huang, Chun Yu Tammy, Mohammadzadeh, Amirmahdi, Barani, Zahra, Salgado, Ruben, Balandin, Alexander A.
Published in Advanced electronic materials (01.04.2020)
Published in Advanced electronic materials (01.04.2020)
Get full text
Journal Article
Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering
Davis, Samuel, Papadopoulos, Nick, Aldrich, Thomas H, Maisonpierre, Peter C, Huang, Tammy, Kovac, Lubomir, Xu, April, Leidich, Raymond, Radziejewska, Elzbieta, Rafique, Ashique, Goldberg, Judah, Jain, Vivek, Bailey, Kevin, Karow, Margaret, Fandl, Jim, Samuelsson, Steven J, Ioffe, Ella, Rudge, John S, Daly, Thomas J, Radziejewski, Czeslaw, Yancopoulos, George D
Published in Nature structural & molecular biology (01.01.2003)
Published in Nature structural & molecular biology (01.01.2003)
Get full text
Journal Article
Angiopoietins 3 and 4: Diverging Gene Counterparts in Mice and Humans
Valenzuela, David M., Griffiths, Jennifer A., Rojas, Jose, Aldrich, Thomas H., Jones, Pamela F., Zhou, Hao, McClain, Joyce, Copeland, Neal G., Gilbert, Debra J., Jenkins, Nancy A., Huang, Tammy, Papadopoulos, Nick, Maisonpierre, Peter C., Davis, Samuel, Yancopoulos, George D.
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.1999)
Get full text
Journal Article
The Efficacy of Artificial Intelligence-Enabled Adaptive Learning Systems From 2010 to 2022 on Learner Outcomes: A Meta-Analysis
Wang, Xiaoman, Huang, Rui “Tammy”, Sommer, Max, Pei, Bo, Shidfar, Poorya, Rehman, Muhammad Shahroze, Ritzhaupt, Albert D., Martin, Florence
Published in Journal of educational computing research (01.10.2024)
Published in Journal of educational computing research (01.10.2024)
Get full text
Journal Article
Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail
Hansen, Johanna, Baum, Alina, Pascal, Kristen E, Russo, Vincenzo, Giordano, Stephanie, Wloga, Elzbieta, Fulton, Benjamin O, Yan, Ying, Koon, Katrina, Patel, Krunal, Chung, Kyung Min, Hermann, Aynur, Ullman, Erica, Cruz, Jonathan, Rafique, Ashique, Huang, Tammy, Fairhurst, Jeanette, Libertiny, Christen, Malbec, Marine, Lee, Wen-Yi, Welsh, Richard, Farr, Glen, Pennington, Seth, Deshpande, Dipali, Cheng, Jemmie, Watty, Anke, Bouffard, Pascal, Babb, Robert, Levenkova, Natasha, Chen, Calvin, Zhang, Bojie, Romero Hernandez, Annabel, Saotome, Kei, Zhou, Yi, Franklin, Matthew, Sivapalasingam, Sumathi, Lye, David Chien, Weston, Stuart, Logue, James, Haupt, Robert, Frieman, Matthew, Chen, Gang, Olson, William, Murphy, Andrew J, Stahl, Neil, Yancopoulos, George D, Kyratsous, Christos A
Published in Science (21.08.2020)
Published in Science (21.08.2020)
Get full text
Journal Article
Web Resource
Dual blockade of IL‐4 and IL‐13 with dupilumab, an IL‐4Rα antibody, is required to broadly inhibit type 2 inflammation
Le Floc’h, Audrey, Allinne, Jeanne, Nagashima, Kirsten, Scott, George, Birchard, Dylan, Asrat, Seblewongel, Bai, Yu, Lim, Wei Keat, Martin, Joel, Huang, Tammy, Potocky, Terra B., Kim, Jee H., Rafique, Ashique, Papadopoulos, Nicholas J., Stahl, Neil, Yancopoulos, George D., Murphy, Andrew J., Sleeman, Matthew A., Orengo, Jamie M.
Published in Allergy (Copenhagen) (01.05.2020)
Published in Allergy (Copenhagen) (01.05.2020)
Get full text
Journal Article
High affinity human Fc specific monoclonal antibodies for capture kinetic analyses of antibody-antigen interactions
Kamat, Vishal, Boutot, Candice, Rafique, Ashique, Granados, Christian, Wang, Jing, Badithe, Ashok, Torres, Marcela, Chatterjee, Ishita, Olsen, Olav, Olson, William, Huang, Tammy
Published in Analytical biochemistry (01.03.2022)
Published in Analytical biochemistry (01.03.2022)
Get full text
Journal Article
Characterization of the Anti-PD-1 Antibody REGN2810 and Its Antitumor Activity in Human PD-1 Knock-In Mice
Burova, Elena, Hermann, Aynur, Waite, Janelle, Potocky, Terra, Lai, Venus, Hong, Seongwon, Liu, Matt, Allbritton, Omaira, Woodruff, Amy, Wu, Qi, D'Orvilliers, Amanda, Garnova, Elena, Rafique, Ashique, Poueymirou, William, Martin, Joel, Huang, Tammy, Skokos, Dimitris, Kantrowitz, Joel, Popke, Jon, Mohrs, Markus, MacDonald, Douglas, Ioffe, Ella, Olson, William, Lowy, Israel, Murphy, Andrew, Thurston, Gavin
Published in Molecular cancer therapeutics (01.05.2017)
Published in Molecular cancer therapeutics (01.05.2017)
Get full text
Journal Article