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Pharmacokinetic parameters of recombinant factor IX Fc fusion protein are not influenced by factor IX antigen levels in subjects from the Phase 3 B‐LONG trial
Sidonio, Robert F., Casiano, Sandra, Falk, Aletta, Altincatal, Arman, Katragadda, Suresh, Santagostino, Elena, Windyga, Jerzy
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2023)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2023)
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Long‐term safety and sustained efficacy for up to 5 years of treatment with recombinant factor IX Fc fusion protein in subjects with haemophilia B: Results from the B‐YOND extension study
Pasi, K. John, Fischer, Kathelijn, Ragni, Margaret, Kulkarni, Roshni, Ozelo, Margareth C., Mahlangu, Johnny, Shapiro, Amy, P’Ng, Stephanie, Chambost, Hervé, Nolan, Beatrice, Bennett, Carolyn, Matsushita, Tadashi, Winding, Bent, Fruebis, Joachim, Yuan, Huixing, Rudin, Dan, Oldenburg, Johannes
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2020)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2020)
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Factor IX assay discrepancies in the setting of liver gene therapy using a hyperfunctional variant factor IX‐Padua
Robinson, Mary M., George, Lindsey A., Carr, Marcus E., Samelson‐Jones, Benjamin J., Arruda, Valder R., Murphy, John E., Rybin, Denis, Rupon, Jeremy, High, Katherine A., Tiefenbacher, Stefan
Published in Journal of thrombosis and haemostasis (01.05.2021)
Published in Journal of thrombosis and haemostasis (01.05.2021)
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Long‐acting recombinant factor IX Fc fusion protein (rFIXFc) for perioperative management of subjects with haemophilia B in the phase 3 B‐LONG study
Powell, Jerry S., Apte, Shashikant, Chambost, Hervé, Hermans, Cedric, Jackson, Shannon, Josephson, Neil C., Mahlangu, Johnny N., Ozelo, Margareth C., Peerlinck, Kathelijne, Pasi, John, Perry, David, Ragni, Margaret V., Wang, Xuefeng, Jiang, Haiyan, Li, Shuanglian, Cristiano, Lynda M., Innes, Alison, Nugent, Karen, Brennan, Aoife, Luk, Alvin, Allen, Geoffrey, Pierce, Glenn F., Robinson, Brian
Published in British journal of haematology (01.01.2015)
Published in British journal of haematology (01.01.2015)
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Matching-Adjusted Indirect Comparison of Recombinant Factor IX Albumin Fusion Protein Versus Recombinant Factor IX Fc Fusion Protein for Weekly Prophylactic Treatment of Hemophilia B
Guillet, Benoit, Yan, Songkai, Hooper, Becky, Drelich, Douglass, Steenkamp, Jason, Tomic, Radovan, Mancuso, Maria Elisa
Published in Advances in therapy (01.02.2024)
Published in Advances in therapy (01.02.2024)
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Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
Manno, Catherine S, Pierce, Glenn F, Arruda, Valder R, Glader, Bertil, Ragni, Margaret, Rasko, John J E, Ozelo, Margareth C, Hoots, Keith, Blatt, Philip, Konkle, Barbara, Dake, Michael, Kaye, Robin, Razavi, Mahmood, Zajko, Albert, Zehnder, James, Rustagi, Pradip, Nakai, Hiroyuki, Chew, Amy, Leonard, Debra, Wright, J Fraser, Lessard, Ruth R, Sommer, Jürg M, Tigges, Michael, Sabatino, Denise, Luk, Alvin, Jiang, Haiyan, Mingozzi, Federico, Couto, Linda, Ertl, Hildegund C, High, Katherine A, Kay, Mark A
Published in Nature medicine (01.03.2006)
Published in Nature medicine (01.03.2006)
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Multicentre, randomized, open-label study of on-demand treatment with two prophylaxis regimens of recombinant coagulation factor IX in haemophilia B subjects
Valentino, L. A., Rusen, L., Elezovic, I., Smith, L. M., Korth-Bradley, J. M., Rendo, P.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.05.2014)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.05.2014)
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Long-acting recombinant coagulation factor IX albumin fusion protein (rIX-FP) in hemophilia B: results of a phase 3 trial
Santagostino, Elena, Martinowitz, Uri, Lissitchkov, Toshko, Pan-Petesch, Brigitte, Hanabusa, Hideji, Oldenburg, Johannes, Boggio, Lisa, Negrier, Claude, Pabinger, Ingrid, von Depka Prondzinski, Mario, Altisent, Carmen, Castaman, Giancarlo, Yamamoto, Koji, Álvarez-Roman, Maria-Teresa, Voigt, Christine, Blackman, Nicole, Jacobs, Iris
Published in Blood (07.04.2016)
Published in Blood (07.04.2016)
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Identifying hemophilia B carriers: Utility of aPTT, factor IX levels and ratios of factor IX to other Vitamin K dependent factors
Shu, Michael, Malcolmson, Caroline, Bosch, Alessandra, Markovic, Teodora, Wakefield, Cindy, Bouskill, Vanessa, Carcao, Manuel
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.07.2024)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.07.2024)
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Long-term safety and efficacy of extended-interval prophylaxis with recombinant factor IX Fc fusion protein (rFIXFc) in subjects with haemophilia B
Pasi, K John, Fischer, Kathelijn, Ragni, Margaret, Nolan, Beatrice, Perry, David J, Kulkarni, Roshni, Ozelo, Margareth, Mahlangu, Johnny, Shapiro, Amy D, Baker, Ross I, Bennett, Carolyn M, Barnes, Christopher, Oldenburg, Johannes, Matsushita, Tadashi, Yuan, Huixing, Ramirez-Santiago, Alejandra, Pierce, Glenn F, Allen, Geoffrey, Mei, Baisong
Published in Thrombosis and haemostasis (2017)
Published in Thrombosis and haemostasis (2017)
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Switching to recombinant factor IX Fc fusion protein prophylaxis results in fewer infusions, decreased factor IX consumption and lower bleeding rates
Powell, Jerry, Shapiro, Amy, Ragni, Margaret, Negrier, Claude, Windyga, Jerzy, Ozelo, Margareth, Pasi, John, Baker, Ross, Potts, James, Li, Shuanglian, Mei, Baisong, Pierce, Glenn F., Robinson, Brian
Published in British journal of haematology (01.01.2015)
Published in British journal of haematology (01.01.2015)
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Factor IX expression in skeletal muscle of a severe hemophilia B patient 10 years after AAV-mediated gene transfer
Buchlis, George, Podsakoff, Gregory M., Radu, Antonetta, Hawk, Sarah M., Flake, Alan W., Mingozzi, Federico, High, Katherine A.
Published in Blood (29.03.2012)
Published in Blood (29.03.2012)
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Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients
Shapiro, Amy D., Ragni, Margaret V., Valentino, Leonard A., Key, Nigel S., Josephson, Neil C., Powell, Jerry S., Cheng, Gregory, Thompson, Arthur R., Goyal, Jaya, Tubridy, Karen L., Peters, Robert T., Dumont, Jennifer A., Euwart, Donald, Li, Lian, Hallén, Bengt, Gozzi, Peter, Bitonti, Alan J., Jiang, Haiyan, Luk, Alvin, Pierce, Glenn F.
Published in Blood (19.01.2012)
Published in Blood (19.01.2012)
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Safety, pharmacokinetics, and pharmacodynamics of a next‐generation subcutaneously administered coagulation factor IX variant, dalcinonacog alfa, in previously treated hemophilia B patients
You, Chur Woo, Hong, Seung‐Beom, Kim, Suyeong, Shin, Ho‐Jin, Kim, Jin Seok, Han, Jung Woo, Kim, Soo‐Jeong, Kim, Do Young, Lee, Martin, Levy, Howard
Published in Journal of thrombosis and haemostasis (01.04.2021)
Published in Journal of thrombosis and haemostasis (01.04.2021)
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Safety and pharmacokinetics of a novel recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) in hemophilia B patients
Santagostino, Elena, Negrier, Claude, Klamroth, Robert, Tiede, Andreas, Pabinger-Fasching, Ingrid, Voigt, Christine, Jacobs, Iris, Morfini, Massimo
Published in Blood (20.09.2012)
Published in Blood (20.09.2012)
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Genetic fusion to albumin improves the pharmacokinetic properties of factor IX
Metzner, Hubert J, Weimer, Thomas, Kronthaler, Ulrich, Lang, Wiegand, Schulte, Stefan
Published in Thrombosis and haemostasis (01.10.2009)
Published in Thrombosis and haemostasis (01.10.2009)
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IDEAL study: A real‐world assessment of pattern of use and clinical outcomes with recombinant coagulation factor IX albumin fusion protein (rIX‐FP) in patients with haemophilia B in Italy
Tagliaferri, Annarita, Molinari, Angelo Claudio, Peyvandi, Flora, Coppola, Antonio, Demartis, Francesco, Biasoli, Chiara, Borchiellini, Alessandra, Cultrera, Dorina, De Cristofaro, Raimondo, Daniele, Filomena, Giordano, Paola, Marchesini, Emanuela, Margaglione, Maurizio, Marino, Renato, Pollio, Berardino, Radossi, Paolo, Santoro, Cristina, Santoro, Rita Carlotta, Siragusa, Sergio, Sottilotta, Gianluca, Tosetto, Alberto, Piscitelli, Lydia, Villa, Maria Rosaria, Zanon, Ezio, Finardi, Adele, Schiavetti, Irene, Vaccari, Daniella, Castaman, Giancarlo
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2023)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2023)
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Prophylaxis with recombinant factor IX Fc fusion protein reduces the risk of bleeding and delays time to first spontaneous bleed event in previously untreated patients with haemophilia B: A post hoc analysis of the PUPs B‐LONG study
Nolan, Beatrice, Recht, Michael, Rendo, Pablo, Falk, Aletta, Foster, Meredith, Casiano, Sandra, Rauch, Antoine, Shapiro, Amy
Published in European journal of haematology (01.10.2024)
Published in European journal of haematology (01.10.2024)
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