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101HEMB01 Is a Phase 1/2 Open-Label, Single Ascending Dose-Finding Trial of DTX101 (AAVrh10FIX) in Patients with Moderate/Severe Hemophilia B That Demonstrated Meaningful but Transient Expression of Human Factor IX (hFIX)
Pipe, Steven, Stine, Kimo, Rajasekhar, Anita, Everington, Tamara, Poma, Allen, Crombez, Eric, Hay, Charles RM
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Randomized comparison of prophylaxis and on-demand regimens with FEIBA NF in the treatment of haemophilia A and B with inhibitors
Antunes, S. V., Tangada, S., Stasyshyn, O., Mamonov, V., Phillips, J., Guzman-Becerra, N., Grigorian, A., Ewenstein, B., Wong, W.-Y.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2014)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2014)
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Long-Term Use of Coagulation Factor IX (Recombinant) Albumin Fusion Protein (rIX-FP) in Previously Treated Patients with Hemophilia B in the Prolong-9FP Program
Lubetsky, Aaron, Martinowitz, Uri, Lissitchkov, Toshko, Voigt, Christine, Wolko, Denise, Jacobs, Iris C., Santagostino, Elena
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Evaluation of efficacy of twice-weekly prophylactic treatment with BeneFIX® (recombinant factor IX) followed by once weekly in children with severe hemophilia B: Six-year data from a local registry
Al-Janabi, Rafal, Salih, Afrah, Alwan, Mohammed
Published in Iraqi Journal of Hematology (01.01.2021)
Published in Iraqi Journal of Hematology (01.01.2021)
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Recombinant Fusion Protein Linking Coagulation Factor IX with Albumin (RIX-FP) in Previously Treated Children < 12 Years of Age with Hemophilia B: Long-Term Efficacy and Safety from an Ongoing Phase 3b Extension Clinical Trial
Kenet, Gili, Brainsky, Andres, Powell, Jerry S., Li, Yanyan, Seifert, Wilfried
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Long-term correction of canine hemophilia B by gene transfer of blood coagulation factor IX mediated by adeno-associated viral vector
Herzog, Roland W., Yang, Edmund Y., Couto, Linda B., Hagstrom, J. Nathan, Elwell, Dan, Fields, Paul A., Burton, Melissa, Bellinger, Dwight A., Read, Marjorie S., Brinkhous, Kenneth M., Podsakoff, Gregory M., Nichols, Timothy C., Kurtzman, Gary J., High, Katherine A.
Published in Nature medicine (01.01.1999)
Published in Nature medicine (01.01.1999)
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Efficacy and Safety Results of Prolong-9FP Clinical Program of Recombinant Fusion Protein Linking Coagulation Factor IX with Albumin (rIX-FP) in Previously Treated Patients with Hemophilia B
Santagostino, Elena, Voigt, Christine, Wolko, Denise, Cole, Grace, Li, Yanyan, Jacobs, Iris C.
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Low Bleeding Rates with Increase or Maintenance of Physical Activity in Patients Treated with Recombinant Factor IX Fc Fusion Protein (rFIXFc) in the B-LONG and Kids B-LONG Studies
Kulkarni, Roshni, Shapiro, Amy D, Windyga, Jerzy, Ragni, Margaret V, Pasi, K John, Ozelo, Margareth Castro, Tsao, Elisa, Mei, Baisong
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Clot waveform of APTT has abnormal patterns in subjects with COVID-19
Shimura, Takuya, Kurano, Makoto, Kanno, Yoshiaki, Ikeda, Mahoko, Okamoto, Koh, Jubishi, Daisuke, Harada, Sohei, Okugawa, Shu, Moriya, Kyoji, Yatomi, Yutaka
Published in Scientific reports (04.03.2021)
Published in Scientific reports (04.03.2021)
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Successful in vivo propagation of factor IX-producing hepatocytes in mice: potential for cell-based therapy in haemophilia B
Tatsumi, Kohei, Ohashi, Kazuo, Kataoka, Miho, Tateno, Chise, Shibata, Masaru, Naka, Hiroyuki, Shima, Midori, Hisanaga, Michiyoshi, Kanehiro, Hiromichi, Okano, Teruo, Yoshizato, Katsutoshi, Nakajima, Yoshiyuki, Yoshioka, Akira
Published in Thrombosis and haemostasis (01.05.2008)
Published in Thrombosis and haemostasis (01.05.2008)
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FIX-Triple, a gain-of-function factor IX variant, improves haemostasis in mouse models without increased risk of thrombosis
Kao, Chung-Yang, Lin, Chia-Ni, Yu, I-Shing, Tao, Mi-Hua, Wu, Hua-Lin, Shi, Guey-Yueh, Yang, Yung-Li, Kao, Jau-Tsuen, Lin, Shu-Wha
Published in Thrombosis and haemostasis (01.08.2010)
Published in Thrombosis and haemostasis (01.08.2010)
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Pharmacokinetic Results of Two Phase III Clinical Studies of Coagulation Factor IX (Recombinant) Albumin Fusion Protein (rIX-FP) in Previously Treated Patients with Hemophilia B (PROLONG-9FP)
Santagostino, Elena, Jacobs, Iris C., Voigt, Christine, Feussner, Annettee, Limsakun, Tharin
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Cellular Immune Responses To Vector In a Gene Therapy Trial For Hemophilia B Using An AAV8 Self-Complementary Factor IX Vector
Basner-Tschakarjan, Etiena, Mingozzi, Federico, Chen, Yifeng, Nathwani, Amit, Tuddenham, Edward, Riddell, Anne, Ng, Catherine, Rustagi, Pradip, Glader, Bertil, Kay, Mark, Reiss, Ulrike M., Nienhuis, Arthur W., Davidoff, Andrew, High, Katherine A.
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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No inhibitor development after continuous infusion of factor concentrates in subjects with bleeding disorders undergoing surgery: a prospective study
Auerswald, G., Bade, A, Haubold, K., Overberg, D., Masurat, S., Moorthi, C.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.05.2013)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.05.2013)
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Protein-Engineered Coagulation Factors for Hemophilia Gene Therapy
Samelson-Jones, Benjamin J., Arruda, Valder R.
Published in Molecular therapy. Methods & clinical development (15.03.2019)
Published in Molecular therapy. Methods & clinical development (15.03.2019)
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Efficacy and Safety of Recombinant Fusion Protein Linking Coagulation Factor IX with Albumin (rIX-FP) in Previously Treated Patients with Hemophilia B Undergoing Major Orthopedic Surgeries
Negrier, Claude, Lepatan, Lynda Mae, Karim, Faralzah, Lienhart, Anne, Wolko, Denise, Voigt, Christine, Jacobs, Iris C., Santagostino, Elena
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Activated factor IX, factor XI and tissue factor identify patients with permanent atrial fibrillation treated with warfarin who are at risk of ischemic stroke
Kusak, Piotr, Czarnecka, Danuta, Gissel, Matthew, Plens, Krzysztof, Butenas, Saulius, Undas, Anetta
Published in Archives of medical science (01.10.2016)
Published in Archives of medical science (01.10.2016)
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Pharmacokinetics, Efficacy and Safety Of a Recombinant Factor IX (BAX326) In Previously-Treated Pediatric Patients < 12 Years Of Age With Severe Or Moderately Severe Hemophilia B
Urasinski, Tomasz, Stasyshyn, Oleksandra, Andreeva, Tatiana, Rusen, Luminita, Perina, Farida, Oh, MyungShin, Chapman, Miranda, Pavlova, Borislava G, Wong, Wing Yen, Abbuehl, Brigitt E.
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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