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Phase I study of BAY 94‐9027, a PEGylated B‐domain‐deleted recombinant factor VIII with an extended half‐life, in subjects with hemophilia A
Coyle, T. E., Reding, M. T., Lin, J. C., Michaels, L. A., Shah, A., Powell, J.
Published in Journal of thrombosis and haemostasis (01.04.2014)
Published in Journal of thrombosis and haemostasis (01.04.2014)
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Extended half‐life pegylated, full‐length recombinant factor VIII for prophylaxis in children with severe haemophilia A
Mullins, E. S., Stasyshyn, O., Alvarez‐Román, M. T., Osman, D., Liesner, R., Engl, W., Sharkhawy, M., Abbuehl, B. E.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.03.2017)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.03.2017)
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First study of extended half-life rFVIIIFc in previously untreated patients with hemophilia A: PUPs A-LONG final results
Königs, Christoph, Ozelo, Margareth C., Dunn, Amy, Kulkarni, Roshni, Nolan, Beatrice, Brown, Simon A., Schiavulli, Michele, Gunawardena, Sriya, Mukhopadhyay, Sutirtha, Jayawardene, Deepthi, Winding, Bent, Carcao, Manuel
Published in Blood (30.06.2022)
Published in Blood (30.06.2022)
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Comparative pharmacokinetics of two extended half‐life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference?
Carcao, Manuel D., Chelle, Pierre, Clarke, Emily, Kim, Lussia, Tiseo, Laura, Morfini, Massimo, Hossain, Taneya, Rand, Margaret L., Brown, Christine, Edginton, Andrea N., Lillicrap, David, Iorio, Alfonso, Blanchette, Victor S.
Published in Journal of thrombosis and haemostasis (01.07.2019)
Published in Journal of thrombosis and haemostasis (01.07.2019)
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LongHest project: A prospective, observational study of extended half‐life treatment in the musculoskeletal health of patients with severe haemophilia A
Cuesta‐Barriuso, Rubén, Pérez‐Llanes, Raúl, Donoso‐Úbeda, Elena, Ucero‐Lozano, Roberto
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.09.2022)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.09.2022)
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Safety, Tolerability and Pharmacokinetics of MEDI8897, an Extended Half-life Single-dose Respiratory Syncytial Virus Prefusion F-targeting Monoclonal Antibody Administered as a Single Dose to Healthy Preterm Infants
Domachowske, Joseph B, Khan, Anis A, Esser, Mark T, Jensen, Kathryn, Takas, Therese, Villafana, Tonya, Dubovsky, Filip, Griffin, M Pamela
Published in The Pediatric infectious disease journal (01.09.2018)
Published in The Pediatric infectious disease journal (01.09.2018)
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Safety, Tolerability, and Pharmacokinetics of MEDI4893, an Investigational, Extended-Half-Life, Anti-Staphylococcus aureus Alpha-Toxin Human Monoclonal Antibody, in Healthy Adults
Yu, Xiang-Qing, Robbie, Gabriel J., Wu, Yuling, Esser, Mark T., Jensen, Kathryn, Schwartz, Howard I., Bellamy, Terramika, Hernandez-Illas, Martha, Jafri, Hasan S.
Published in Antimicrobial agents and chemotherapy (01.01.2017)
Published in Antimicrobial agents and chemotherapy (01.01.2017)
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Clinical outcomes of low‐dose pharmacokinetic‐guided extended half‐life versus low‐dose standard half‐life factor VIII concentrate prophylaxis in haemophilia A patients
Rakmanotham, Arunothai, Moonla, Chatphatai, Sosothikul, Darintr
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2023)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2023)
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Recombinant full-length factor VIII (FVIII) and extended half-life FVIII products in prophylaxis - new insight provided by pharmacokinetic modelling
Gringeri, A., Wolfsegger, M., Steinitz, K. N., Reininger, A. J.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.05.2015)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.05.2015)
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Efficacy and safety of pegylated full-length recombinant factor VIII with extended half-life for perioperative haemostasis in haemophilia A patients
Brand, B., Gruppo, R., Wynn, T. T., Griskevicius, L., Lopez Fernandez, M. F., Chapman, M., Dvorak, T., Pavlova, B. G., Abbuehl, B. E.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.07.2016)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.07.2016)
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BIO89-100, a GlycoPEGylated FGF21 Analog, Improved Serum Lipids and Extended Half-Life in a Controlled Single Ascending Dose Trial in Healthy Subjects
Margalit, Maya, Chen, Chao-Yin, Tseng, Leo, Rosenstock, Moti, Mansbach, Hank
Published in Journal of clinical lipidology (01.07.2020)
Published in Journal of clinical lipidology (01.07.2020)
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Long‐term safety and sustained efficacy for up to 5 years of treatment with recombinant factor IX Fc fusion protein in subjects with haemophilia B: Results from the B‐YOND extension study
Pasi, K. John, Fischer, Kathelijn, Ragni, Margaret, Kulkarni, Roshni, Ozelo, Margareth C., Mahlangu, Johnny, Shapiro, Amy, P’Ng, Stephanie, Chambost, Hervé, Nolan, Beatrice, Bennett, Carolyn, Matsushita, Tadashi, Winding, Bent, Fruebis, Joachim, Yuan, Huixing, Rudin, Dan, Oldenburg, Johannes
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2020)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2020)
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Adoption of Prophylaxis in the United States in the Era of Extended Half-Life Factor Concentrates
Malec, Lynn M., White, Gilbert C., Croteau, Stacy E., Cheng, Dunlei, Ragni, Margaret V.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Extended Half-Life of the Double-Chain Recombinant Factor VIII-Fc Fusion Protein (FRSW107) in Hemophilia a Patients
Xue, Feng, Sun, Jing, Chen, Yun, Zhang, Xinsheng, Sun, Haiyan, Wang, Yali, Yang, Renchi
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Real World Use of Extended Half-Life Products and the Impact on Bleeding Events and Joint Health in the United States
Malec, Lynn M., Witmer, Char M, Jaffray, Julie, Kouides, Peter A., Haley, Kristina M., Sidonio, Robert F., Cheng, Dunlei, Abshire, Thomas C., White, Gilbert C., Ragni, Margaret V.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Recombinant factor VIII Fc fusion protein for the treatment of severe haemophilia A: Final results from the ASPIRE extension study
Nolan, Beatrice, Mahlangu, Johnny, Pabinger, Ingrid, Young, Guy, Konkle, Barbara A., Barnes, Chris, Nogami, Keiji, Santagostino, Elena, Pasi, K. John, Khoo, Liane, Winding, Bent, Yuan, Huixing, Fruebis, Joachim, Rudin, Dan, Oldenburg, Johannes
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.05.2020)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.05.2020)
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Real Life Population Pharmacokinetics Modelling of Eight Factors VIII in Patients with Severe Haemophilia A: Is It Always Relevant to Switch to an Extended Half-Life?
Allard, Quentin, Djerada, Zoubir, Pouplard, Claire, Repessé, Yohann, Desprez, Dominique, Galinat, Hubert, Frotscher, Birgit, Berger, Claire, Harroche, Annie, Ryman, Anne, Flaujac, Claire, Chamouni, Pierre, Guillet, Benoît, Volot, Fabienne, Szymezak, Jean, Nguyen, Philippe, Cazaubon, Yoann
Published in Pharmaceutics (21.04.2020)
Published in Pharmaceutics (21.04.2020)
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An Evaluation of Safety with an Extended Half-Life, Pegylated, Full-Length Recombinant Factor VIII (BAX 855) in the Treatment of 243 Patients with Hemophilia a
Engl, Werner, Patrone, Lisa, Jacqueline, Dyck-Jones, Tangada, Srilatha D., Abbuehl, Brigitt E.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Joint Bleeding Patterns in Patients Treated Prophylactically with an Extended Half-Life, Pegylated, Full-Length Recombinant Factor VIII (BAX 855)
Manco-Johnson, Marilyn J., Ma, Alice D., Klamroth, Robert, Engl, Werner, Griparic, Lorena, Dyck-Jones, Jacqueline A, Abbuehl, Brigitt E.
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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