A randomized single and multiple ascending dose study in healthy volunteers of LTI‐291, a centrally penetrant glucocerebrosidase activator
Heijer, Jonas M., Kruithof, Annelieke C., Amerongen, Guido, Kam, Marieke L., Thijssen, Eva, Grievink, Hendrika W., Moerland, Matthijs, Walker, Mike, Been, Kees, Skerlj, Renato, Justman, Craig, Dudgeon, Lindsay, Lansbury, Peter, Cullen, Valerie C., Hilt, Dana C., Groeneveld, Geert Jan
Published in British journal of clinical pharmacology (01.09.2021)
Published in British journal of clinical pharmacology (01.09.2021)
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Journal Article
The Etiology of Parkinson’s Disease: New Perspectives from Gene-Environment Interactions
Bogers, Jolien S., Bloem, Bastiaan R., Den Heijer, Jonas M.
Published in Journal of Parkinson's disease (01.01.2023)
Published in Journal of Parkinson's disease (01.01.2023)
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Journal Article
A Biomarker Study in Patients with GBA1‐Parkinson's Disease and Healthy Controls
Heijer, Jonas M., Cullen, Valerie C., Pereira, Diana R., Yavuz, Yalcin, Kam, Marieke L., Grievink, Hendrika W., Moerland, Matthijs, Leymarie, Nancy, Khatri, Kshitij, Sollomoni, Imelda, Spitalny, Leslie, Dungeon, Lindsay, Hilt, Dana C., Justman, Craig, Lansbury, Peter, Groeneveld, Geert Jan
Published in Movement disorders (01.05.2023)
Published in Movement disorders (01.05.2023)
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Journal Article
A Phase 1B Trial in GBA1‐Associated Parkinson's Disease of BIA‐28‐6156, a Glucocerebrosidase Activator
Heijer, Jonas M., Kruithof, Annelieke C., Moerland, Matthijs, Walker, Mike, Dudgeon, Lindsay, Justman, Craig, Solomini, Imelda, Splitalny, Leslie, Leymarie, Nancy, Khatri, Kshitij, Cullen, Valerie C., Hilt, Dana C., Groeneveld, Geert Jan, Lansbury, Peter
Published in Movement disorders (01.07.2023)
Published in Movement disorders (01.07.2023)
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Journal Article
A Large‐Scale Full GBA1 Gene Screening in Parkinson's Disease in the Netherlands
Heijer, Jonas M., Cullen, Valerie C., Quadri, Marialuisa, Schmitz, Arnoud, Hilt, Dana C., Lansbury, Peter, Berendse, Henk W., Berg, Wilma D.J., Bie, Rob M.A., Boertien, Jeffrey M., Boon, Agnita J.W., Contarino, M. Fiorella, Hilten, Jacobus J., Hoff, Jorrit I., Mierlo, Tom, Munts, Alex G., Plas, Anne A., Ponsen, Mirthe M., Baas, Frank, Majoor‐Krakauer, Danielle, Bonifati, Vincenzo, Laar, Teus, Groeneveld, Geert J.
Published in Movement disorders (01.09.2020)
Published in Movement disorders (01.09.2020)
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Journal Article
A Randomized Trial Assessing the Safety, Pharmacokinetics, and Efficacy During Morning Off of AZ‐009
Thijssen, Eva, Heijer, Jonas, Puibert, David, Moss, Laurence, Lei, Mingzu, Hasegawa, David, Keum, Kyo, Mochel, Ken, Ezzeldin Sharaf, Mohammed, Alfredson, Tom, Zeng, Wenxiang, Brummelen, Emilie, Naranda, Tatjana, Groeneveld, Geert Jan
Published in Movement disorders (01.04.2022)
Published in Movement disorders (01.04.2022)
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Journal Article
Intronic Haplotypes in GBA Modify Age at Diagnosis of Parkinson's: Replication in a Subgroup
O'Sullivan, Justin M., Heijer, Jonas M., Groeneveld, Geert J., Cooper, Antony A.
Published in Movement disorders (01.06.2021)
Published in Movement disorders (01.06.2021)
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Journal Article
Safety and pharmacokinetics of multiple dosing with inhalable apomorphine (AZ-009), and its efficacy in a randomized crossover study in Parkinson's disease patients
Thijssen, Eva, den Heijer, Jonas M., Puibert, David, van Brummelen, Emilie M.J., Naranda, Tatjana, Groeneveld, Geert Jan
Published in Parkinsonism & related disorders (01.04.2022)
Published in Parkinsonism & related disorders (01.04.2022)
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Journal Article
Good Clinical Trials by removing defensive interpretation of Good Clinical Practice guidelines
Heijer, Jonas M., Heuberger, Jules A. A. C., Hijma, Hemme, Kruithof, Annelieke C., Smeden, Jeroen, Groeneveld, Geert Jan, Burggraaf, Jacobus, Cohen, Adam
Published in British journal of clinical pharmacology (01.12.2021)
Published in British journal of clinical pharmacology (01.12.2021)
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Journal Article
The relation between cortisol and functional connectivity in people with and without stress‐sensitive epilepsy
Heijer, Jonas M., Otte, Willem M., Diessen, Eric, Campen, Jolien S., Lorraine Hompe, E., Jansen, Floor E., Joels, Marian, Braun, Kees P. J., Sander, Josemir W., Zijlmans, Maeike
Published in Epilepsia (Copenhagen) (01.01.2018)
Published in Epilepsia (Copenhagen) (01.01.2018)
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Journal Article
A Placebo‐Controlled Study to Assess the Sensitivity of Finger Tapping to Medication Effects in Parkinson's Disease
Thijssen, Eva, Makai‐Bölöni, Soma, Brummelen, Emilie, Heijer, Jonas, Yavuz, Yalcin, Doll, Robert‐Jan, Groeneveld, Geert Jan
Published in Movement disorders clinical practice (Hoboken, N.J.) (01.11.2022)
Published in Movement disorders clinical practice (Hoboken, N.J.) (01.11.2022)
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Journal Article
Brain Bio-Energetic State Does Not Correlate to Muscle Mitochondrial Function in Huntington’s Disease
van Diemen, Marcus P.J., Hart, Ellen P., Hameeteman, Pieter W., Coppen, Emma M., Winder, Jessica Y., den Heijer, Jonas, Moerland, Matthijs, Kan, Hermien, van der Grond, Jeroen, Webb, Andrew, Roos, Raymund A.C., Groeneveld, Geert Jan
Published in Journal of Huntington's disease (01.01.2020)
Published in Journal of Huntington's disease (01.01.2020)
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Journal Article