Characterization of cytochrome P450 isoforms involved in sequential two-step bioactivation of diclofenac to reactive p-benzoquinone imines
den Braver, Michiel W., den Braver-Sewradj, Shalenie P., Vermeulen, Nico P.E., Commandeur, Jan N.M.
Published in Toxicology letters (24.06.2016)
Published in Toxicology letters (24.06.2016)
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Journal Article
Citizens' Perception and Concerns on Chemical Exposures and Human Biomonitoring-Results from a Harmonized Qualitative Study in Seven European Countries
Matisāne, Linda, Knudsen, Lisbeth E, Lobo Vicente, Joana, Uhl, Maria, Katsonouri, Andromachi, van den Brand, Annick D, Berman, Tamar, Dimovska, Mirjana, Anastasi, Eleni, Thoma, Anthi, Középesy, Szilvia, Gjorgjev, Dragan, Borota Popovska, Mirjana, den Braver-Sewradj, Shalenie P, Szigeti, Tamás, Topuzovska Latkovikj, Marija, Mārtiņsone, Inese, Akūlova, Lāsma, Paegle, Linda
Published in International journal of environmental research and public health (25.05.2022)
Published in International journal of environmental research and public health (25.05.2022)
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Journal Article
Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations
den Braver-Sewradj, Shalenie P, den Braver, Michiel W, Toorneman, Robin M, van Leeuwen, Stephanie, Zhang, Yongjie, Dekker, Stefan J, Vermeulen, Nico P. E, Commandeur, Jan N. M, Vos, J. Chris
Published in Chemical research in toxicology (19.02.2018)
Published in Chemical research in toxicology (19.02.2018)
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Journal Article
Inter-donor variability of phase I/phase II metabolism of three reference drugs in cryopreserved primary human hepatocytes in suspension and monolayer
den Braver-Sewradj, Shalenie P., den Braver, Michiel W., Vermeulen, Nico P.E., Commandeur, Jan N.M., Richert, Lysiane, Vos, J. Chris
Published in Toxicology in vitro (01.06.2016)
Published in Toxicology in vitro (01.06.2016)
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Journal Article
Inter-individual variability in activity of the major drug metabolizing enzymes in liver homogenates of 20 Individuals
Vos, J Chris, den Braver-Sewradj, Shalenie P, den Braver, Michiel W, van Dijk, Marc, Zhang, Yongjie, Dekker, Stefan J, Wijaya, Lukas, Vermeulen, Nico P E, Richert, Lysiane, Commandeur, Jan N M
Published in Current drug metabolism (01.01.2018)
Published in Current drug metabolism (01.01.2018)
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Journal Article
Substitution of bisphenol A: a review of the carcinogenicity, reproductive toxicity, and endocrine disruption potential of alternative substances
den Braver-Sewradj, Shalenie P., van Spronsen, Rob, Hessel, Ellen V. S.
Published in Critical reviews in toxicology (07.02.2020)
Published in Critical reviews in toxicology (07.02.2020)
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Journal Article
Glutathione S -Transferase P1 Protects Against Amodiaquine Quinoneimines-Induced Cytotoxicity but Does Not Prevent Activation of Endoplasmic Reticulum Stress in HepG2 Cells
Zhang, Yongjie, den Braver-Sewradj, Shalenie P, den Braver, Michiel W, Hiemstra, Steven, Vermeulen, Nico P E, van de Water, Bob, Commandeur, Jan N M, Vos, J C
Published in Frontiers in pharmacology (18.04.2018)
Published in Frontiers in pharmacology (18.04.2018)
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Journal Article
Occupational exposure to hexavalent chromium. Part I. Hazard assessment of non-cancer health effects
Hessel, Ellen V.S., Staal, Yvonne C.M., Piersma, Aldert H., den Braver-Sewradj, Shalenie P., Ezendam, Janine
Published in Regulatory toxicology and pharmacology (01.11.2021)
Published in Regulatory toxicology and pharmacology (01.11.2021)
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Journal Article
Occupational exposure to hexavalent chromium. Part II. Hazard assessment of carcinogenic effects
den Braver-Sewradj, Shalenie P., van Benthem, Jan, Staal, Yvonne C.M., Ezendam, Janine, Piersma, Aldert H., Hessel, Ellen V.S.
Published in Regulatory toxicology and pharmacology (01.11.2021)
Published in Regulatory toxicology and pharmacology (01.11.2021)
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Journal Article
A prioritization strategy for functional alternatives to bisphenol A in food contact materials
van den Brand, Annick D, Hessel, Ellen V S, Rijk, Rinus, van de Ven, Bianca, Leijten, Niels M, Rorije, Emiel, den Braver-Sewradj, Shalenie P
Published in Critical reviews in toxicology (10.05.2024)
Published in Critical reviews in toxicology (10.05.2024)
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Journal Article
Human glutathione S-transferases- and NAD(P)H:quinone oxidoreductase 1-catalyzed inactivation of reactive quinoneimines of amodiaquine and N-desethylamodiaquine: Possible implications for susceptibility to amodiaquine-induced liver toxicity
Zhang, Yongjie, den Braver-Sewradj, Shalenie P., Vos, J. Chris, Vermeulen, Nico P.E., Commandeur, Jan N.M.
Published in Toxicology letters (05.06.2017)
Published in Toxicology letters (05.06.2017)
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Journal Article
Direct comparison of UDP-glucuronosyltransferase and cytochrome P450 activities in human liver microsomes, plated and suspended primary human hepatocytes from five liver donors
den Braver-Sewradj, Shalenie P., den Braver, Michiel W., Baze, Audrey, Decorde, Joachim, Fonsi, Massimiliano, Bachellier, Philippe, Vermeulen, Nico P.E., Commandeur, Jan N.M., Richert, Lysiane, Vos, J. Chris
Published in European journal of pharmaceutical sciences (15.11.2017)
Published in European journal of pharmaceutical sciences (15.11.2017)
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Journal Article