Search Results - "del Prado, Miriam" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid Coadministration

Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid Coadministration

by Zhao, Genshi, Green, Colin F, Hui, Yu-Hua, Prieto, Lourdes, Shepard, Robert, Dong, Sucai, Wang, Tao, Tan, Bo, Gong, Xueqian, Kays, Lisa, Johnson, Robert L, Wu, Wenjuan, Bhattachar, Shobha, Del Prado, Miriam, Gillig, James R, Fernandez, Maria-Carmen, Roth, Ken D, Buchanan, Sean, Kuo, Ming-Shang, Geeganage, Sandaruwan, Burkholder, Timothy P
Published in Molecular cancer therapeutics (01.12.2017)

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Journal Article

Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine

Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine

by Gelbert, Lawrence M., Cai, Shufen, Lin, Xi, Sanchez-Martinez, Concepcion, del Prado, Miriam, Lallena, Maria Jose, Torres, Raquel, Ajamie, Rose T., Wishart, Graham N., Flack, Robert Steven, Neubauer, Blake Lee, Young, Jamie, Chan, Edward M., Iversen, Philip, Cronier, Damien, Kreklau, Emiko, de Dios, Alfonso
Published in Investigational new drugs (01.10.2014)

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Journal Article

Efficient synthesis of 4,4-disubstituted-3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides

Efficient synthesis of 4,4-disubstituted-3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides

by Domı́nguez, Esteban, de Blas, Jesús, del Prado, Miriam, Aranda, M.Teresa, Carreño, M.Carmen, Garcı́a Ruano, José L.
Published in Tetrahedron letters (09.12.2000)

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Journal Article

Regioselective synthesis of 3,6-disubstituted-2-aminoimidazo[1,2- a]pyridines

Regioselective synthesis of 3,6-disubstituted-2-aminoimidazo[1,2- a]pyridines

by Jaramillo, Carlos, Carretero, Juan Carlos, de Diego, J.Eugenio, del Prado, Miriam, Hamdouchi, Chafiq, Roldán, José Luis, Sánchez-Martı́nez, Concha
Published in Tetrahedron letters (09.12.2002)

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Journal Article

EZH2의 억제제

EZH2의 억제제

by YU KUO LONG, NGUYEN ANH QUAN HANNAH, RICHETT MICHAEL ENRICO, GUO DEQI, DOMINGUEZ ESTEBAN, YIP YVONNE YEE MAI, RODRIGUEZ MICHAEL JOHN, DEL PRADO MIRIAM FILADELFA, MADER MARY MARGARET
Year of Publication 23.03.2018

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Patent

Asymmetric aziridination by reaction of chiral N-sulfinylimines with sulfur ylides: Stereoselectivity improvement by use of tert-butylsulfinyl group as chiral auxiliary

Asymmetric aziridination by reaction of chiral N-sulfinylimines with sulfur ylides: Stereoselectivity improvement by use of tert-butylsulfinyl group as chiral auxiliary

by García Ruano, JoséL, Fernández, Inmaculada, Prado Catalina, Miriam del, Cruz, Ana Alcudia
Published in Tetrahedron: asymmetry (01.12.1996)

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Journal Article

Imidazolyl benzimidazoles and imidazo[4,5- b]pyridines as potent p38α MAP kinase inhibitors with excellent in vivo antiinflammatory properties

Imidazolyl benzimidazoles and imidazo[4,5- b]pyridines as potent p38α MAP kinase inhibitors with excellent in vivo antiinflammatory properties

by Mader, Mary, de Dios, Alfonso, Shih, Chuan, Bonjouklian, Rosanne, Li, Tiechao, White, Wesley, de Uralde, Beatriz López, Sánchez-Martinez, Concepción, del Prado, Miriam, Jaramillo, Carlos, de Diego, Eugenio, Martín Cabrejas, Luisa M., Dominguez, Carmen, Montero, Carlos, Shepherd, Timothy, Dally, Robert, Toth, John E., Chatterjee, Arindam, Pleite, Sehila, Blanco-Urgoiti, Jaime, Perez, Leticia, Barberis, Mario, Lorite, María José, Jambrina, Enrique, Nevill, C. Richard, Lee, Paul A., Schultz, Richard C., Wolos, Jeffrey A., Li, Li C., Campbell, Robert M., Anderson, Bryan D.
Published in Bioorganic & medicinal chemistry letters (2008)

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Journal Article

GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: In vitro profile and in vivo analgesic efficacy

by Martinez-Perez, Jose A., Iyengar, Smriti, Shannon, Harlan E., Bleakman, David, Alt, Andrew, Clawson, David K., Arnold, Brian M., Bell, Michael G., Bleisch, Thomas J., Castaño, Ana M., Del Prado, Miriam, Dominguez, Esteban, Escribano, Ana M., Filla, Sandra A., Ho, Ken H., Hudziak, Kevin J., Jones, Carrie K., Mateo, Ana, Mathes, Brian M., Mattiuz, Edward L., Ogden, Ann Marie L., Simmons, Rosa Maria A., Stack, Douglas R., Stratford, Robert E., Winter, Mark A., Wu, Zhipei, Ornstein, Paul L.
Published in Bioorganic & medicinal chemistry letters (01.12.2013)

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Journal Article

GluK1 antagonists from 6-(carboxy)phenyl decahydroisoquinoline derivatives. SAR and evaluation of a prodrug strategy for oral efficacy in pain models

GluK1 antagonists from 6-(carboxy)phenyl decahydroisoquinoline derivatives. SAR and evaluation of a prodrug strategy for oral efficacy in pain models

by Martinez-Perez, Jose A., Iyengar, Smriti, Shannon, Harlan E., Bleakman, David, Alt, Andrew, Arnold, Brian M., Bell, Michael G., Bleisch, Thomas J., Castaño, Ana M., Del Prado, Miriam, Dominguez, Esteban, Escribano, Ana M., Filla, Sandra A., Ho, Ken H., Hudziak, Kevin J., Jones, Carrie K., Mateo, Ana, Mathes, Brian M., Mattiuz, Edward L., Ogden, Ann Marie L., Simmons, Rosa Maria A., Stack, Douglas R., Stratford, Robert E., Winter, Mark A., Wu, Zhipei, Ornstein, Paul L.
Published in Bioorganic & medicinal chemistry letters (01.12.2013)

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Journal Article

Abstract B233: Identification and characterization of LY2835219: A potent oral inhibitor of the cyclin-dependent kinases 4 and 6 (CDK4/6) with broad in vivo antitumor activity

Abstract B233: Identification and characterization of LY2835219: A potent oral inhibitor of the cyclin-dependent kinases 4 and 6 (CDK4/6) with broad in vivo antitumor activity

by Gelbert, Lawrence M., Cai, Shufen, Lin, Xi, Sanchez-Martinez, Concepcion, del Prado, Miriam, Lallena, Maria Jose, Torres, Raquel, Ajamie, Rose T., Kreklau, Emiko, Wishart, Graham N., Flack, Robert Steven, Neubauer, Blake, Young, Jamie, Chan, Edward M., Iversen, Phillip, Cronier, Damien, De Dios, Alfonso
Published in Molecular cancer therapeutics (12.11.2011)

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Journal Article

Design of Potent and Selective 2-Aminobenzimidazole-Based p38α MAP Kinase Inhibitors with Excellent in Vivo Efficacy

Design of Potent and Selective 2-Aminobenzimidazole-Based p38α MAP Kinase Inhibitors with Excellent in Vivo Efficacy

by de Dios, Alfonso, Shih, Chuan, López de Uralde, Beatriz, Sánchez, Concepción, del Prado, Miriam, Martín Cabrejas, Luisa M, Pleite, Sehila, Blanco-Urgoiti, Jaime, Lorite, María José, Nevill, C. Richard, Bonjouklian, Rosanne, York, Jeremy, Vieth, Michal, Wang, Yong, Magnus, Nicholas, Campbell, Robert M, Anderson, Bryan D, McCann, Denis J, Giera, Deborah D, Lee, Paul A, Schultz, Richard M, Li, Johnson, Lea M, Wolos, Jeffrey A
Published in Journal of medicinal chemistry (07.04.2005)

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Journal Article

Imidazo[1,2-b]pyridazines, Novel Nucleus with Potent and Broad Spectrum Activity against Human Picornaviruses: Design, Synthesis, and Biological Evaluation

Imidazo[1,2-b]pyridazines, Novel Nucleus with Potent and Broad Spectrum Activity against Human Picornaviruses: Design, Synthesis, and Biological Evaluation

by Hamdouchi, Chafiq, Sanchez-Martinez, Concha, Gruber, Joseph, del Prado, Miriam, Lopez, Javier, Rubio, Almudena, Heinz, Beverly A
Published in Journal of medicinal chemistry (25.09.2003)

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Journal Article

Stereoselective Addition of α-Sulfinyl Carbanions to N-p-tolylsulfinylketimines: Synthesis of Optically Pure 1,2,2‘-Trialkyl-2-aminoethanols

Stereoselective Addition of α-Sulfinyl Carbanions to N-p-tolylsulfinylketimines: Synthesis of Optically Pure 1,2,2‘-Trialkyl-2-aminoethanols

by García Ruano, José L, Alemán, José, del Prado, Miriam, Fernández, Inmaculada
Published in Journal of organic chemistry (25.06.2004)

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Journal Article

Two Prodrugs of Potent and Selective GluR5 Kainate Receptor Antagonists Actives in Three Animal Models of Pain

Two Prodrugs of Potent and Selective GluR5 Kainate Receptor Antagonists Actives in Three Animal Models of Pain

by Dominguez, Esteban, Iyengar, Smriti, Shannon, Harlan E, Bleakman, David, Alt, Andrew, Arnold, Brian M, Bell, Michael G, Bleisch, Thomas J, Buckmaster, Jennifer L, Castano, Ana M, Del Prado, Miriam, Escribano, Ana, Filla, Sandra A, Ho, Ken H, Hudziak, Kevin J, Jones, Carrie K, Martinez-Perez, Jose A, Mateo, Ana, Mathes, Brian M, Mattiuz, Edward L, Ogden, Ann Marie L, Simmons, Rosa Maria A, Stack, Douglas R, Stratford, Robert E, Winter, Mark A, Wu, Zhipei, Ornstein, Paul L
Published in Journal of medicinal chemistry (30.06.2005)

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Journal Article

Aminoimidazo[1,2- a]pyridines as a new structural class of cyclin-dependent kinase inhibitors. Part 1: Design, synthesis, and biological evaluation

Aminoimidazo[1,2- a]pyridines as a new structural class of cyclin-dependent kinase inhibitors. Part 1: Design, synthesis, and biological evaluation

by Jaramillo, Carlos, de Diego, J. Eugenio, Hamdouchi, Chafiq, Collins, Elizabeth, Keyser, Heather, Sánchez-Martı́nez, Concha, del Prado, Miriam, Norman, Bryan, Brooks, Harold B., Watkins, Scott A., Spencer, Charles D., Dempsey, Jack Alan, Anderson, Bryan D., Campbell, Robert M., Leggett, Tellie, Patel, Bharvin, Schultz, Richard M., Espinosa, Juan, Vieth, Michal, Zhang, Faming, Timm, David E.
Published in Bioorganic & medicinal chemistry letters (20.12.2004)

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Journal Article

Additions of enantiopure alpha-sulfinyl carbanions to (S)-N-sulfinimines: Asymmetric synthesis of beta-amino sulfoxides and beta-amino alcohols

Additions of enantiopure alpha-sulfinyl carbanions to (S)-N-sulfinimines: Asymmetric synthesis of beta-amino sulfoxides and beta-amino alcohols

by Ruano, JLG, Alcudia, A, del Prado, M, Barros, D, Maestro, MC, Fernandez
Published in Journal of organic chemistry (19.05.2000)

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Journal Article

Design of potent and selective 2-aminobenzimidazole-based p38alpha MAP kinase inhibitors with excellent in vivo efficacy

Design of potent and selective 2-aminobenzimidazole-based p38alpha MAP kinase inhibitors with excellent in vivo efficacy

by de Dios, Alfonso, Shih, Chuan, López de Uralde, Beatriz, Sánchez, Concepción, del Prado, Miriam, Martín Cabrejas, Luisa M, Pleite, Sehila, Blanco-Urgoiti, Jaime, Lorite, María José, Nevill, Jr, C Richard, Bonjouklian, Rosanne, York, Jeremy, Vieth, Michal, Wang, Yong, Magnus, Nicholas, Campbell, Robert M, Anderson, Bryan D, McCann, Denis J, Giera, Deborah D, Lee, Paul A, Schultz, Richard M, Li, Li C, Johnson, Lea M, Wolos, Jeffrey A
Published in Journal of medicinal chemistry (07.04.2005)

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Journal Article

Two prodrugs of potent and selective GluR5 kainate receptor antagonists actives in three animal models of pain : 2005 American Chemical Society Award for Computers in Chemical and Pharmaceutical Research

Two prodrugs of potent and selective GluR5 kainate receptor antagonists actives in three animal models of pain : 2005 American Chemical Society Award for Computers in Chemical and Pharmaceutical Research

by DOMINGUEZ, Esteban, IYENGAR, Smriti, DEL PRADO, Miriam, ESCRIBANO, Ana, FILLA, Sandra A, HO, Ken H, HUDZIAK, Kevin J, JONES, Carrie K, MARTINEZ-PEREZ, Jose A, MATEO, Ana, MATHES, Brian M, MATTIUZ, Edward L, SHANNON, Harlan E, OGDEN, Ann Marie L, SIMMONS, Rosa Maria A, STACK, Douglas R, STRATFORD, Robert E, WINTER, Mark A, ZHIPEI WU, ORNSTEIN, Paul L, BLEAKMAN, David, ALT, Andrew, ARNOLD, Brian M, BELL, Michael G, BLEISCH, Thomas J, BUCKMASTER, Jennifer L, CASTANO, Ana M
Published in Journal of medicinal chemistry (2005)

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Journal Article

Additions of Enantiopure α-Sulfinyl Carbanions to (S)-N-Sulfinimines: Asymmetric Synthesis of β-Amino Sulfoxides and β-Αmino Alcohols

Additions of Enantiopure α-Sulfinyl Carbanions to (S)-N-Sulfinimines: Asymmetric Synthesis of β-Amino Sulfoxides and β-Αmino Alcohols

by García Ruano, José L, Alcudia, Ana, del Prado, Miriam, Barros, David, Maestro, M. Carmen, Fernández, Inmaculada
Published in Journal of organic chemistry (19.05.2000)

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Journal Article

INHIBITORS OF EZH2

INHIBITORS OF EZH2

by GUO, Deqi, YIP, Yvonne Yee Mai, NGUYEN, Anh-Quan Hannah, RICHETT, Michael Enrico, DEL PRADO, Miriam Filadelfa, YU, Kuo-Long, MADER, Mary Margaret, DOMINGUEZ, Esteban, RODRIGUEZ, Michael John
Year of Publication 28.12.2021

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