Disruption of the Cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation
LUTGENS, E, LUTGENS, S. P. M, FISHER, A, LONG, C. J, SAFTIG, P, BLACK, D, DAEMEN, M. J. A. P, CLEUTJENS, K. B. J. M, FABER, B. C. G, HEENEMAN, S, GIJBELS, M. M. J, DE WINTHER, M. P. J, FREDERIK, P, VAN DER MADE, I, DAUGHERTY, A, SIJBERS, A. M
Published in Circulation (New York, N.Y.) (03.01.2006)
Published in Circulation (New York, N.Y.) (03.01.2006)
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Journal Article
Epigenetic control through histone modifications regulates macrophages during atherosclerosis
Neele, A.E, Van den Bossche, J, Hoeksema, M.A, de Winther, M.P.J
Published in Atherosclerosis (01.08.2014)
Published in Atherosclerosis (01.08.2014)
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Journal Article
Targeting Hdac3 limits foam cell formation and improves atherosclerotic plaque stability
Van den Bossche, J, Hoeksema, M.A, Gijbels, M.J.J, van der Velden, S, Sijm, A, Neele, A.E, Seijkens, T, Meiler, S, Boshuizen, M.C.S, Boon, L, Mullican, S.E, Spann, N.J, Dallinga-Thie, G.M, Cleutjens, J.P, Lazar, M.A, de Vries, C.J, Biessen, E.A.L, Daemen, M.J.A.P, Lutgens, E, de Winther, M.P.J
Published in Atherosclerosis (01.08.2014)
Published in Atherosclerosis (01.08.2014)
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Journal Article
Histone methyltransferase DOT1L regulates macrophage inflammatory responses and lipid metabolism
Willemsen, L., Neele, A.E., Prange, K.H.M., Roomen, C.P.A.A., Bruinenberg, D. A.M. Lotgerink, Den Toom, M., Griffith, G.R., Chen, H.-J., Beckers, L., Bosmans, L.A., Binder, C.J., Van Leeuwen, F., Jacobs, H., De Winther, M.P.J.
Published in Atherosclerosis (01.08.2021)
Published in Atherosclerosis (01.08.2021)
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Journal Article
The polycomb repressive complex 2 (PRC2) in macrophages and atherosclerosis
Neele, A.E., Willemsen, L., Chen, H.-J., Gijbels, M.J.J., Roomen, C.P.A.A., Griffith, G.R., Van Der Velden, S., Hoeksema, M.A., Prange, K.H.M., Boshuizen, M.C., Van Den Bossche, J., Tool, A.T., Matlung, H.L., Van Den Berg, T.K., Lutgens, E., De Winther, M.P.J.
Published in Atherosclerosis (01.08.2021)
Published in Atherosclerosis (01.08.2021)
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Single Cell Rna-Sequencing Identifies Numerous Cell Sub-Types And Suggests Lineage Plasticity In Human Atherosclerotic Plaques
Mokry, M., Depuydt, M.A.C., Prange, K.H.M., Slenders, L., Elbersen, D., Granneman, L.E.C., de Jager, S.C.A., Slütter, B.A., Bot, I., de Winther, M.P.J., Kuiper, J., Asselbergs, F.W., van der Laan, S.W., Pasterkamp, G.
Published in Atherosclerosis (01.08.2019)
Published in Atherosclerosis (01.08.2019)
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Microanatomy Of Advanced Human Atherosclerotic Plaques Through Single-Cell Transcriptomics
Depuydt, M., Prange, K.H.M., Slenders, L., Elbersen, D., Boltjes, A., de Jager, S.C.A., Slütter, B.A., Bot, I., van der Laan, S.W., Mokry, M., Pasterkamp, G., de Winther, M.P.J., Kuiper, J.
Published in Atherosclerosis (01.08.2019)
Published in Atherosclerosis (01.08.2019)
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Journal Article
Blocking CD40-TRAF6 interactions by small-molecule inhibitor 6860766 ameliorates the complications of diet-induced obesity in mice
van den Berg, S M, Seijkens, T T P, Kusters, P J H, Zarzycka, B, Beckers, L, den Toom, M, Gijbels, M J J, Chatzigeorgiou, A, Weber, C, de Winther, M P J, Chavakis, T, Nicolaes, G A F, Lutgens, E
Published in International Journal of Obesity (01.05.2015)
Published in International Journal of Obesity (01.05.2015)
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Journal Article
Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages’ transition into a pro-inflammatory state
Bosmans, Laura A, van Tiel, Claudia M, Aarts, Suzanne A B M, Willemsen, Lisa, Baardman, Jeroen, van Os, Bram W, Toom, Myrthe den, Beckers, Linda, Ahern, David J, Levels, Johannes H M, Jongejan, Aldo, Moerland, Perry D, Verberk, Sanne G S, den Bossche, Jan van, de Winther, Menno M P J, Weber, Christian, Atzler, Dorothee, Monaco, Claudia, Gerdes, Norbert, Shami, Annelie, Lutgens, Esther
Published in Cardiovascular research (22.05.2023)
Published in Cardiovascular research (22.05.2023)
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Journal Article
Leukocyte CD40L deficiency affects the CD25 + CD4 T cell population but does not affect atherosclerosis
Smook, M.L.F., Heeringa, P., Damoiseaux, J.G.M.C., Daemen, M.J.A.P., de Winther, M.P.J., Gijbels, M.J.J., Beckers, L., Lutgens, E., Cohen Tervaert, J.W.
Published in Atherosclerosis (01.12.2005)
Published in Atherosclerosis (01.12.2005)
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Journal Article
Spatial correlation of trace elements with morphological features of atherosclerotic plaques
Roijers, R.B., Dutta, R.K., Mutsaers, P.H.A., Gijbels, M.J.J., de Winther, M.P.J., de Goeij, J.J.M., van der Vusse, G.J.
Published in Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms (01.04.2005)
Published in Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms (01.04.2005)
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Journal Article
The effect of scavenger receptor A1 (SRA1) on arterosclerosis
de Winther, M.P.J., Kanters, E., Gijbels, M.J.J., van Dijk, K.W., van Vlijmen, B.J.M., Kraal, G., Hofker, M.H.
Published in Atherosclerosis (01.07.2000)
Published in Atherosclerosis (01.07.2000)
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Journal Article
Macrophage specific overexpression of the human macrophage scavenger receptor, using A 180 kb yeast artificial chromosome, reduces atherosclerosis in low density lipoprotein deficient mice
De Winther, M.P.J., van Dijk, K. Willems, Havekes, L.M., Hofker, M.H.
Published in Atherosclerosis (01.05.1999)
Published in Atherosclerosis (01.05.1999)
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Journal Article
Tu-P7:181 Hematopoietic deficiency of P55 TNF receptor negatively regulates plasma lipid levels and results in smaller atherosclerotic lesions
Xanthoulea, S., Ambagts, T., Gijbels, M.J.J., Van Der Made, I., Hofker, M.H., De Winther, M.P.J.
Published in Atherosclerosis. Supplements (2006)
Published in Atherosclerosis. Supplements (2006)
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Journal Article
W12-IS-001 The role of NF-icB in atherosclerosis
Hofkert, M.H., Kanterss, E., Gijbelst, M.J.J., Van der Made, I., Vergouwet, M., Pasparakis, M., Heeringa, P., Kraals, G., de Winther, M.P.J.
Published in Atherosclerosis. Supplements (01.04.2005)
Published in Atherosclerosis. Supplements (01.04.2005)
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Journal Article
Apolipophorin III levels in Locusta migratoria. Development regulation of gene expression and hemolymph protein concentration
Winther, M.P.J. de, Weers, P.M.M, Bogerd, J, Horst, D.J. van der (Biochemical Physiology Research Group, Department of Experimental Zoology, Utrehct University, Padualaan 8, 3584 CH Utrecht (Netherlands))
Published in Journal of Insect Physiology (United Kingdom) (1996)
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Published in Journal of Insect Physiology (United Kingdom) (1996)
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