A deep sequencing approach to uncover the miRNOME in the human heart
Leptidis, Stefanos, El Azzouzi, Hamid, Lok, Sjoukje I, de Weger, Roel, Olieslagers, Servé, Olieslagers, Serv, Kisters, Natasja, Silva, Gustavo J, Heymans, Stephane, Cuppen, Edwin, Berezikov, Eugene, De Windt, Leon J, da Costa Martins, Paula
Published in PloS one (27.02.2013)
Published in PloS one (27.02.2013)
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Journal Article
A versatile multiplexed assay to quantify intracellular ROS and cell viability in 3D on-a-chip models
Soragni, Camilla, Rabussier, Gwenaëlle, Lanz, Henriëtte L., Bircsak, Kristin M., de Windt, Leon J., Trietsch, Sebastiaan J., Murdoch, Colin E., Ng, Chee Ping
Published in Redox biology (01.11.2022)
Published in Redox biology (01.11.2022)
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Journal Article
MicroRNAs in heart failure: from biomarker to target for therapy
Vegter, Eline L., van der Meer, Peter, de Windt, Leon J., Pinto, Yigal M., Voors, Adriaan A.
Published in European journal of heart failure (01.05.2016)
Published in European journal of heart failure (01.05.2016)
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Journal Article
Regulation of fetal gene expression in heart failure
Dirkx, Ellen, da Costa Martins, Paula A., De Windt, Leon J.
Published in Biochimica et biophysica acta (01.12.2013)
Published in Biochimica et biophysica acta (01.12.2013)
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Journal Article
Apoptosis-inducing factor regulates skeletal muscle progenitor cell number and muscle phenotype
Armand, Anne-Sophie, Laziz, Iman, Djeghloul, Dounia, Lécolle, Sylvie, Bertrand, Anne T, Biondi, Olivier, De Windt, Leon J, Chanoine, Christophe
Published in PloS one (04.11.2011)
Published in PloS one (04.11.2011)
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Journal Article
MicroRNA-221/222 Family Counteracts Myocardial Fibrosis in Pressure Overload–Induced Heart Failure
Verjans, Robin, Peters, Tim, Beaumont, Francisco Javier, van Leeuwen, Rick, van Herwaarden, Tessa, Verhesen, Wouter, Munts, Chantal, Bijnen, Mitchell, Henkens, Michiel, Diez, Javier, de Windt, Leon J, van Nieuwenhoven, Frans A, van Bilsen, Marc, Goumans, Marie José, Heymans, Stephane, González, Arantxa, Schroen, Blanche
Published in Hypertension (Dallas, Tex. 1979) (01.02.2018)
Published in Hypertension (Dallas, Tex. 1979) (01.02.2018)
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Journal Article
MiR423-5p As a Circulating Biomarker for Heart Failure
Tijsen, Anke J, Creemers, Esther E, Moerland, Perry D, de Windt, Leon J, van der Wal, Allard C, Kok, Wouter E, Pinto, Yigal M
Published in Circulation research (02.04.2010)
Published in Circulation research (02.04.2010)
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Journal Article
The innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC
Frantz, Stefan, Falcao‐Pires, Ines, Balligand, Jean‐Luc, Bauersachs, Johann, Brutsaert, Dirk, Ciccarelli, Michele, Dawson, Dana, de Windt, Leon J., Giacca, Mauro, Hamdani, Nazha, Hilfiker‐Kleiner, Denise, Hirsch, Emilio, Leite‐Moreira, Adelino, Mayr, Manuel, Thum, Thomas, Tocchetti, Carlo G., van der Velden, Jolanda, Varricchi, Gilda, Heymans, Stephane
Published in European journal of heart failure (01.03.2018)
Published in European journal of heart failure (01.03.2018)
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Journal Article
Healthy and diseased placental barrier on-a-chip models suitable for standardized studies
Rabussier, Gwenaëlle, Bünter, Ivan, Bouwhuis, Josse, Soragni, Camilla, van Zijp, Torben, Ng, Chee Ping, Domansky, Karel, de Windt, Leon J., Vulto, Paul, Murdoch, Colin E., Bircsak, Kristin M., Lanz, Henriëtte L.
Published in Acta biomaterialia (01.07.2023)
Published in Acta biomaterialia (01.07.2023)
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Journal Article
Lung ischemia-reperfusion injury: a molecular and clinical view on a complex pathophysiological process
den Hengst, Willem A, Gielis, Jan F, Lin, Judy Y, Van Schil, Paul E, De Windt, Leon J, Moens, An L
Published in American journal of physiology. Heart and circulatory physiology (01.11.2010)
Published in American journal of physiology. Heart and circulatory physiology (01.11.2010)
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Journal Article
Preclinical Development of a MicroRNA-Based Therapy for Elderly Patients With Myocardial Infarction
Gupta, Shashi Kumar, PhD, Foinquinos, Ariana, MSc, Thum, Sabrina, Remke, Janet, Zimmer, Karina, Bauters, Christophe, MD, de Groote, Pascal, MD, Boon, Reinier A., PhD, de Windt, Leon J., PhD, Preissl, Sebastian, PhD, Hein, Lutz, MD, Batkai, Sandor, MD, PhD, Pinet, Florence, PhD, Thum, Thomas, MD, PhD
Published in Journal of the American College of Cardiology (04.10.2016)
Published in Journal of the American College of Cardiology (04.10.2016)
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Journal Article
The Hypoxia-Inducible MicroRNA Cluster miR-199a∼214 Targets Myocardial PPARδ and Impairs Mitochondrial Fatty Acid Oxidation
el Azzouzi, Hamid, Leptidis, Stefanos, Dirkx, Ellen, Hoeks, Joris, van Bree, Bianca, Brand, Karl, McClellan, Elizabeth A., Poels, Ella, Sluimer, Judith C., van den Hoogenhof, Maarten M.G., Armand, Anne-Sophie, Yin, Xiaoke, Langley, Sarah, Bourajjaj, Meriem, Olieslagers, Serve, Krishnan, Jaya, Vooijs, Marc, Kurihara, Hiroki, Stubbs, Andrew, Pinto, Yigal M., Krek, Wilhelm, Mayr, Manuel, Martins, Paula A. da Costa, Schrauwen, Patrick, De Windt, Leon J.
Published in Cell metabolism (03.09.2013)
Published in Cell metabolism (03.09.2013)
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Journal Article
Genomic instability in the naturally and prematurely aged myocardium
De Majo, Federica, Martens, Leonie, Hegenbarth, Jana-Charlotte, Rühle, Frank, Hamczyk, Magda R., Nevado, Rosa M., Andrés, Vicente, Hilbold, Erika, Bär, Christian, Thum, Thomas, de Boer, Martine, Duncker, Dirk J., Schroen, Blanche, Armand, Anne-Sophie, Stoll, Monika, De Windt, Leon J.
Published in Proceedings of the National Academy of Sciences - PNAS (07.09.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (07.09.2021)
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Journal Article
Comparison of different chemically modified inhibitors of miR-199b in vivo
Duygu, Burcu, Juni, Rio, Ottaviani, Lara, Bitsch, Nicole, Wit, Jan B.M., de Windt, Leon J., da Costa Martins, Paula A.
Published in Biochemical pharmacology (01.01.2019)
Published in Biochemical pharmacology (01.01.2019)
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Journal Article
Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure
Raso, Andrea, Dirkx, Ellen, Philippen, Leonne E., Fernandez-Celis, Amaya, De Majo, Federica, Sampaio-Pinto, Vasco, Sansonetti, Marida, Juni, Rio, el Azzouzi, Hamid, Calore, Martina, Bitsch, Nicole, Olieslagers, Servé, Oerlemans, Martinus I.F.J., Huibers, Manon M., de Weger, Roel A., Reckman, Yolan J., Pinto, Yigal M., Zentilin, Lorena, Zacchigna, Serena, Giacca, Mauro, da Costa Martins, Paula A., López-Andrés, Natalia, De Windt, Leon J.
Published in Molecular therapy (06.03.2019)
Published in Molecular therapy (06.03.2019)
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Journal Article
Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure
Dirkx, Ellen, Gladka, Monika M., Philippen, Leonne E., Armand, Anne-Sophie, Kinet, Virginie, Leptidis, Stefanos, el Azzouzi, Hamid, Salic, Kanita, Bourajjaj, Meriem, da Silva, Gustavo J. J., Olieslagers, Servé, van der Nagel, Roel, de Weger, Roel, Bitsch, Nicole, Kisters, Natasja, Seyen, Sandrine, Morikawa, Yuka, Chanoine, Christophe, Heymans, Stephane, Volders, Paul G. A., Thum, Thomas, Dimmeler, Stefanie, Cserjesi, Peter, Eschenhagen, Thomas, da Costa Martins, Paula A., De Windt, Leon J.
Published in Nature cell biology (01.11.2013)
Published in Nature cell biology (01.11.2013)
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Journal Article
A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration
Raso, Andrea, Dirkx, Ellen, Sampaio-Pinto, Vasco, el Azzouzi, Hamid, Cubero, Ryan J., Sorensen, Daniel W., Ottaviani, Lara, Olieslagers, Servé, Huibers, Manon M., de Weger, Roel, Siddiqi, Sailay, Moimas, Silvia, Torrini, Consuelo, Zentillin, Lorena, Braga, Luca, Nascimento, Diana S., da Costa Martins, Paula A., van Berlo, Jop H., Zacchigna, Serena, Giacca, Mauro, De Windt, Leon J.
Published in Nature communications (10.08.2021)
Published in Nature communications (10.08.2021)
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