The necessity of incorporating non-genetic risk factors into polygenic risk score models
van Dam, Sipko, Folkertsma, Pytrik, Castela Forte, Jose, de Vries, Dylan H., Herrera Cunillera, Camila, Gannamani, Rahul, Wolffenbuttel, Bruce H. R.
Published in Scientific reports (20.02.2023)
Published in Scientific reports (20.02.2023)
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Journal Article
Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response
de Vries, Dylan H, Matzaraki, Vasiliki, Bakker, Olivier B, Brugge, Harm, Westra, Harm-Jan, Netea, Mihai G, Franke, Lude, Kumar, Vinod, van der Wijst, Monique G P
Published in PLoS pathogens (01.04.2020)
Published in PLoS pathogens (01.04.2020)
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Journal Article
Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure
Oelen, Roy, de Vries, Dylan H., Brugge, Harm, Gordon, M. Grace, Vochteloo, Martijn, Ye, Chun J., Westra, Harm-Jan, Franke, Lude, van der Wijst, Monique G. P.
Published in Nature communications (07.06.2022)
Published in Nature communications (07.06.2022)
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Journal Article
An integrative approach for building personalized gene regulatory networks for precision medicine
van der Wijst, Monique G P, de Vries, Dylan H, Brugge, Harm, Westra, Harm-Jan, Franke, Lude
Published in Genome medicine (19.12.2018)
Published in Genome medicine (19.12.2018)
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Journal Article
Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data
Li, Shuang, Schmid, Katharina T, de Vries, Dylan H, Korshevniuk, Maryna, Losert, Corinna, Oelen, Roy, van Blokland, Irene V, Groot, Hilde E, Swertz, Morris A, van der Harst, Pim, Westra, Harm-Jan, van der Wijst, Monique G P, Heinig, Matthias, Franke, Lude
Published in Genome Biology (18.04.2023)
Published in Genome Biology (18.04.2023)
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Journal Article
shRNAs Targeting a Common KCNQ1 Variant Could Alleviate Long-QT1 Disease Severity by Inhibiting a Mutant Allele
Cócera-Ortega, Lucía, Wilders, Ronald, Kamps, Selina C, Fabrizi, Benedetta, Huber, Irit, van der Made, Ingeborg, van den Bout, Anouk, de Vries, Dylan K, Gepstein, Lior, Verkerk, Arie O, Pinto, Yigal M, Tijsen, Anke J
Published in International journal of molecular sciences (06.04.2022)
Published in International journal of molecular sciences (06.04.2022)
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Journal Article
Lactobacillus reuteri Colonisation of Extremely Preterm Infants in a Randomised Placebo-Controlled Trial
Spreckels, Johanne E, Wejryd, Erik, Marchini, Giovanna, Jonsson, Baldvin, de Vries, Dylan H, Jenmalm, Maria C, Landberg, Eva, Sverremark-Ekström, Eva, Martí, Magalí, Abrahamsson, Thomas
Published in Microorganisms (Basel) (2021)
Published in Microorganisms (Basel) (2021)
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Journal Article
Modeling the atrioventricular conduction axis using human pluripotent stem cell-derived cardiac assembloids
Li, Jiuru, Wiesinger, Alexandra, Fokkert, Lianne, Bakker, Priscilla, de Vries, Dylan K., Tijsen, Anke J., Pinto, Yigal M., Verkerk, Arie O., Christoffels, Vincent M., Boink, Gerard J.J., Devalla, Harsha D.
Published in Cell stem cell (07.11.2024)
Published in Cell stem cell (07.11.2024)
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Journal Article
Deconvolution of bulk blood eQTL effects into immune cell subpopulations
Aguirre-Gamboa, Raúl, de Klein, Niek, di Tommaso, Jennifer, Claringbould, Annique, van der Wijst, Monique Gp, de Vries, Dylan, Brugge, Harm, Oelen, Roy, Võsa, Urmo, Zorro, Maria M, Chu, Xiaojin, Bakker, Olivier B, Borek, Zuzanna, Ricaño-Ponce, Isis, Deelen, Patrick, Xu, Cheng-Jiang, Swertz, Morris, Jonkers, Iris, Withoff, Sebo, Joosten, Irma, Sanna, Serena, Kumar, Vinod, Koenen, Hans J P M, Joosten, Leo A B, Netea, Mihai G, Wijmenga, Cisca, Franke, Lude, Li, Yang
Published in BMC bioinformatics (12.06.2020)
Published in BMC bioinformatics (12.06.2020)
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Journal Article
A comparison of myocardial magnetic resonance extracellular volume mapping at 3 T against histology of tissue collagen in severe aortic valve stenosis and obstructive hypertrophic cardiomyopathy
Bakermans, Adrianus J., Kouwenhoven, Merel, de Vos, Judith, de Vries, Dylan K., Reckman, Yolan J., Farag, Emile S., Koolbergen, David R., Kluin, Jolanda, Nederveen, Aart J., Strijkers, Gustav J., Boekholdt, S. Matthijs
Published in Magma (New York, N.Y.) (01.10.2023)
Published in Magma (New York, N.Y.) (01.10.2023)
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Journal Article
Quantification of Myocardial Creatine and Triglyceride Content in the Human Heart: Precision and Accuracy of in vivo Proton Magnetic Resonance Spectroscopy
Bakermans, Adrianus J., Boekholdt, S. Matthijs, Vries, Dylan K., Reckman, Yolan J., Farag, Emile S., Heer, Paul, Uthman, Laween, Denis, Simone W., Zuurbier, Coert J., Houtkooper, Riekelt H., Koolbergen, David R., Kluin, Jolanda, Planken, R. Nils, Lamb, Hildo J., Webb, Andrew G., Strijkers, Gustav J., Beard, Daniel A., Jeneson, Jeroen A.L., Nederveen, Aart J.
Published in Journal of magnetic resonance imaging (01.08.2021)
Published in Journal of magnetic resonance imaging (01.08.2021)
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Journal Article
Effective questionnaire-based prediction models for type 2 diabetes across several ethnicities: a model development and validation study
Kokkorakis, Michail, Folkertsma, Pytrik, van Dam, Sipko, Sirotin, Nicole, Taheri, Shahrad, Chagoury, Odette, Idaghdour, Youssef, Henning, Robert H., Forte, José Castela, Mantzoros, Christos S., de Vries, Dylan H., Wolffenbuttel, Bruce H.R.
Published in EClinicalMedicine (01.10.2023)
Published in EClinicalMedicine (01.10.2023)
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Journal Article
Prevalence and architecture of de novo mutations in developmental disorders
McRae, Jeremy F, Clayton, Stephen, Mason, Laura E, Tivey, Adrian R, Ahmed, Munaza, Awada, Jana, Balasubramanian, Meena, Banka, Siddharth, Bennett, Chris, Bernhard, Birgitta, Bevan, A. Paul, Blair, Edward, Blyth, Moira, Burn, John, Castle, Bruce, Clasper, Susan, Collins, Amanda, Collinson, Morag N, Dabir, Tabib, Davidson, Rosemarie, Davies, Sally, Dean, John, Donnai, Dian, Ellard, Sian, Ellis, Ian, Everest, Sarah, Foulds, Nicola, Fryer, Alan, Gaunt, Lorraine, Goudie, David, Gray, Emma, Greene, Philip, Gribble, Susan, Henderson, Alex, Hildyard, Lucy, Holden, Simon, Holder, Muriel, Ingram, Stuart, Jackson, Andrew, Kaemba, Beckie, Kazembe, Sandra, Kinning, Esther, Kraus, Alison, Kumar, V. K. Ajith, Lachlan, Katherine, Lam, Wayne, Lim, Derek, Longman, Cheryl, Lynch, Sally A, Maher, Eddy, Maye, Una, McKay, Kirsten, McWilliam, Catherine, Metcalfe, Kay, Morgan, Sian, Murday, Victoria, Murphy, Helen, Nemeth, Andrea, Nevitt, Louise, Newbury-Ecob, Ruth, Park, Soo-Mi, Paterson, Joan, Payne, Stewart, Perrett, Daniel, Pratt, Norman, Quarrell, Oliver, Randall, Josh, Rankin, Julia, Raymond, Lucy, Robert, Leema, Roberts, Paul, Saggar, Anand, Samant, Shalaka, Sampson, Julian, Sandford, Richard, Selby, Ann, Sequeira, Cheryl, Shearing, Emma, Smith, Audrey, Smith, Kath, Splitt, Miranda, Suri, Mohnish, Sutton, Vivienne, Tatton-Brown, Kate, Temple, I. Karen, Turner, Claire, Varghese, Vinod, Vasudevan, Pradeep, Vogt, Julie, Wakeling, Emma, Wilcox, Sarah, Williams, Denise, Williams, Nicola, Wilson, Louise, Wright, Michael, Yates, Laura, Yau, Michael, Wright, Caroline F, FitzPatrick, David R, Barrett, Jeffrey C
Published in Nature (London) (23.02.2017)
Published in Nature (London) (23.02.2017)
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Journal Article
Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language
Snijders Blok, Lot, Rousseau, Justine, Twist, Joanna, Ehresmann, Sophie, Takaku, Motoki, Venselaar, Hanka, Rodan, Lance H., Nowak, Catherine B., Douglas, Jessica, Swoboda, Kathryn J., Steeves, Marcie A., Sahai, Inderneel, Stumpel, Connie T. R. M., Stegmann, Alexander P. A., Wheeler, Patricia, Willing, Marcia, Fiala, Elise, Kochhar, Aaina, Gibson, William T., Cohen, Ana S. A., Agbahovbe, Ruky, Innes, A. Micheil, Au, P. Y. Billie, Rankin, Julia, Anderson, Ilse J., Skinner, Steven A., Louie, Raymond J., Warren, Hannah E., Afenjar, Alexandra, Keren, Boris, Nava, Caroline, Buratti, Julien, Isapof, Arnaud, Rodriguez, Diana, Lewandowski, Raymond, Propst, Jennifer, van Essen, Ton, Choi, Murim, Lee, Sangmoon, Chae, Jong H., Price, Susan, Schnur, Rhonda E., Douglas, Ganka, Wentzensen, Ingrid M., Zweier, Christiane, Reis, André, Bialer, Martin G., Moore, Christine, Koopmans, Marije, Brilstra, Eva H., Monroe, Glen R., van Gassen, Koen L. I., van Binsbergen, Ellen, Newbury-Ecob, Ruth, Bownass, Lucy, Bader, Ingrid, Mayr, Johannes A., Wortmann, Saskia B., Jakielski, Kathy J., Strand, Edythe A., Kloth, Katja, Bierhals, Tatjana, Roberts, John D., Petrovich, Robert M., Machida, Shinichi, Kurumizaka, Hitoshi, Lelieveld, Stefan, Pfundt, Rolph, Jansen, Sandra, Deriziotis, Pelagia, Faivre, Laurence, Thevenon, Julien, Assoum, Mirna, Shriberg, Lawrence, Kleefstra, Tjitske, Brunner, Han G., Wade, Paul A., Fisher, Simon E., Campeau, Philippe M.
Published in Nature communications (02.05.2019)
Published in Nature communications (02.05.2019)
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Journal Article
Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language
Blok, Lot Snijders, Rousseau, Justine, Twist, Joanna, Ehresmann, Sophie, Takaku, Motoki, Venselaar, Hanka, Rodan, Lance H., Nowak, Catherine B., Douglas, Jessica, Swoboda, Kathryn J., Steeves, Marcie A., Sahai, Inderneel, Stumpel, Connie T. R. M., Stegmann, Alexander P. A., Wheeler, Patricia, Willing, Marcia, Fiala, Elise, Kochhar, Aaina, Gibson, William T., Cohen, Ana S. A., Agbahovbe, Ruky, Innes, A. Micheil, Au, P. Y. Billie, Rankin, Julia, Anderson, Ilse J., Skinner, Steven A., Louie, Raymond J., Warren, Hannah E., Afenjar, Alexandra, Keren, Boris, Nava, Caroline, Buratti, Julien, Isapof, Arnaud, Rodriguez, Diana, Lewandowski, Raymond, Propst, Jennifer, van Essen, Ton, Choi, Murim, Lee, Sangmoon, Chae, Jong H., Price, Susan, Schnur, Rhonda E., Douglas, Ganka, Wentzensen, Ingrid M., Zweier, Christiane, Reis, André, Bialer, Martin G., Moore, Christine, Koopmans, Marije, Brilstra, Eva H., Monroe, Glen R., van Gassen, Koen L. I., van Binsbergen, Ellen, Newbury-Ecob, Ruth, Bownass, Lucy, Bader, Ingrid, Mayr, Johannes A., Wortmann, Saskia B., Jakielski, Kathy J., Strand, Edythe A., Kloth, Katja, Bierhals, Tatjana, Roberts, John D., Petrovich, Robert M., Machida, Shinichi, Kurumizaka, Hitoshi, Lelieveld, Stefan, Pfundt, Rolph, Jansen, Sandra, Deriziotis, Pelagia, Faivre, Laurence, Thevenon, Julien, Assoum, Mirna, Shriberg, Lawrence, Kleefstra, Tjitske, Brunner, Han G., Wade, Paul A., Fisher, Simon E., Campeau, Philippe M.
Published in Nature communications (15.02.2019)
Published in Nature communications (15.02.2019)
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Journal Article
Single-cell eQTLGen Consortium: a personalized understanding of disease
van der Wijst, Monique G. P, de Vries, Dylan H, Groot, Hilde E, Trynka, Gosia, Hon, Chung-Chau, Nawijn, Martijn C, Idaghdour, Youssef, van der Harst, Pim, Ye, Chun J, Powell, Joseph, Theis, Fabian J, Mahfouz, Ahmed, Heinig, Matthias, Franke, Lude
Year of Publication 27.09.2019
Year of Publication 27.09.2019
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Journal Article
Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data
Li, Shuang, Schmid, Katharina T, De Vries, Dylan, Korshevniuk, Maryna, Oelen, Roy, Irene Van Blokland, Consortium, Bios, Consortium, Sc-Eqtlgen, Groot, Hilde E, Swertz, Morris A, Pim Van Der Harst, Harm-Jan Westra, Van Der Wijst, Monique, Heinig, Matthias, Franke, Lude
Published in bioRxiv (20.04.2022)
Published in bioRxiv (20.04.2022)
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