Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system
Wu, Yue, Cui, Zhenling, Huang, Yen-Hua, de Veer, Simon J., Aralov, Andrey V., Guo, Zhong, Moradi, Shayli V., Hinton, Alexandra O., Deuis, Jennifer R., Guo, Shaodong, Chen, Kai-En, Collins, Brett M., Vetter, Irina, Herzig, Volker, Jones, Alun, Cooper, Matthew A., King, Glenn F., Craik, David J., Alexandrov, Kirill, Mureev, Sergey
Published in Nature communications (11.01.2022)
Published in Nature communications (11.01.2022)
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Journal Article
Sunflower Trypsin Inhibitor‐1 (SFTI‐1): Sowing Seeds in the Fields of Chemistry and Biology
Veer, Simon J., White, Andrew M., Craik, David J.
Published in Angewandte Chemie International Edition (06.04.2021)
Published in Angewandte Chemie International Edition (06.04.2021)
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Journal Article
Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides
White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas, Craik, David J.
Published in Angewandte Chemie International Edition (06.07.2020)
Published in Angewandte Chemie International Edition (06.07.2020)
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Journal Article
Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases
Yap, Kuok, Du, Junqiao, Rehm, Fabian B. H., Tang, Shyn Ric, Zhou, Yan, Xie, Jing, Wang, Conan K., de Veer, Simon J., Lua, Linda H. L., Durek, Thomas, Craik, David J.
Published in Nature protocols (01.03.2021)
Published in Nature protocols (01.03.2021)
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Journal Article
Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition
de Veer, Simon J, Swedberg, Joakim E, Akcan, Muharrem, Rosengren, K Johan, Brattsand, Maria, Craik, David J, Harris, Jonathan M
Published in Biochemical journal (15.07.2015)
Published in Biochemical journal (15.07.2015)
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Journal Article
Substrate-Guided Design of Selective FXIIa Inhibitors Based on the Plant-Derived Momordica cochinchinensis Trypsin Inhibitor-II (MCoTI-II) Scaffold
Swedberg, Joakim E, Mahatmanto, Tunjung, Abdul Ghani, Hafiza, de Veer, Simon J, Schroeder, Christina I, Harris, Jonathan M, Craik, David J
Published in Journal of medicinal chemistry (11.08.2016)
Published in Journal of medicinal chemistry (11.08.2016)
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Journal Article
Kallikrein-Related Peptidase 5 Contributes to H3N2 Influenza Virus Infection in Human Lungs
Magnen, Mélia, Gueugnon, Fabien, Guillon, Antoine, Baranek, Thomas, Thibault, Virginie C, Petit-Courty, Agnès, de Veer, Simon J, Harris, Jonathan, Humbles, Alison A, Si-Tahar, Mustapha, Courty, Yves
Published in Journal of virology (15.08.2017)
Published in Journal of virology (15.08.2017)
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Journal Article
Characterising the Subsite Specificity of Urokinase‐Type Plasminogen Activator and Tissue‐Type Plasminogen Activator using a Sequence‐Defined Peptide Aldehyde Library
Li, Choi Yi, de Veer, Simon J., Law, Ruby H. P., Whisstock, James C., Craik, David J., Swedberg, Joakim E.
Published in Chembiochem : a European journal of chemical biology (02.01.2019)
Published in Chembiochem : a European journal of chemical biology (02.01.2019)
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Journal Article
Potent, multi-target serine protease inhibition achieved by a simplified β-sheet motif
Chen, Xingchen, Riley, Blake T, de Veer, Simon J, Hoke, David E, Van Haeften, Jessica, Leahy, Darren, Swedberg, Joakim E, Brattsand, Maria, Hartfield, Perry J, Buckle, Ashley M, Harris, Jonathan M
Published in PloS one (2019)
Published in PloS one (2019)
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Journal Article
Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14
de Veer, Simon J., Swedberg, Joakim E., Parker, Edward A., Harris, Jonathan M.
Published in Biological chemistry (01.05.2012)
Published in Biological chemistry (01.05.2012)
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Journal Article
Proteases and proteomics: Cutting to the core of human skin pathologies
de Veer, Simon J., Furio, Laetitia, Harris, Jonathan M., Hovnanian, Alain
Published in Proteomics. Clinical applications (01.06.2014)
Published in Proteomics. Clinical applications (01.06.2014)
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Journal Article
Cyclotides as Tools in Chemical Biology
de Veer, Simon J, Weidmann, Joachim, Craik, David J
Published in Accounts of chemical research (18.07.2017)
Published in Accounts of chemical research (18.07.2017)
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Journal Article
Proteases: common culprits in human skin disorders
de Veer, Simon J, Furio, Laetitia, Harris, Jonathan M, Hovnanian, Alain
Published in Trends in molecular medicine (01.03.2014)
Published in Trends in molecular medicine (01.03.2014)
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Journal Article
Enzymatic C‑Terminal Protein Engineering with Amines
Rehm, Fabian B. H, Tyler, Tristan J, Yap, Kuok, de Veer, Simon J, Craik, David J, Durek, Thomas
Published in Journal of the American Chemical Society (24.11.2021)
Published in Journal of the American Chemical Society (24.11.2021)
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Journal Article
Nucleation of a key beta-turn promotes cyclotide oxidative folding
Tian, Sixin, de Veer, Simon J., Durek, Thomas, Wang, Conan K., Craik, David J.
Published in The Journal of biological chemistry (01.04.2024)
Published in The Journal of biological chemistry (01.04.2024)
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Journal Article
Enzymatic C‐to‐C Protein Ligation
Rehm, Fabian B. H., Tyler, Tristan J., Veer, Simon J., Craik, David J., Durek, Thomas
Published in Angewandte Chemie International Edition (07.03.2022)
Published in Angewandte Chemie International Edition (07.03.2022)
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Journal Article
An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human β‑Factor XIIa in a Cyclotide Scaffold
Liu, Wenyu, de Veer, Simon J, Huang, Yen-Hua, Sengoku, Toru, Okada, Chikako, Ogata, Kazuhiro, Zdenek, Christina N, Fry, Bryan G, Swedberg, Joakim E, Passioura, Toby, Craik, David J, Suga, Hiroaki
Published in Journal of the American Chemical Society (10.11.2021)
Published in Journal of the American Chemical Society (10.11.2021)
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