miR-27b Modulates Insulin Signaling in Hepatocytes by Regulating Insulin Receptor Expression
Benito-Vicente, Asier, Uribe, Kepa B, Rotllan, Noemi, Ramírez, Cristina M, Jebari-Benslaiman, Shifa, Goedeke, Leigh, Canfrán-Duque, Alberto, Galicia-García, Unai, Saenz De Urturi, Diego, Aspichueta, Patricia, Suárez, Yajaira, Fernández-Hernando, Carlos, Martín, Cesar
Published in International journal of molecular sciences (17.11.2020)
Published in International journal of molecular sciences (17.11.2020)
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Journal Article
Atorvastatin provides a new lipidome improving early regeneration after partial hepatectomy in osteopontin deficient mice
Nuñez-Garcia, Maitane, Gomez-Santos, Beatriz, Saenz de Urturi, Diego, Mestre, Daniela, Gonzalez-Romero, Francisco, Buque, Xabier, Gutiérrez-de Juan, Virginia, Martinez-Chantar, María Luz, Syn, Wing-Kin, Fresnedo, Olatz, Aspichueta, Patricia
Published in Scientific reports (02.10.2018)
Published in Scientific reports (02.10.2018)
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Journal Article
Suppression of angiopoietin-like 4 reprograms endothelial cell metabolism and inhibits angiogenesis
Chaube, Balkrishna, Citrin, Kathryn M., Sahraei, Mahnaz, Singh, Abhishek K., de Urturi, Diego Saenz, Ding, Wen, Pierce, Richard W., Raaisa, Raaisa, Cardone, Rebecca, Kibbey, Richard, Fernández-Hernando, Carlos, Suárez, Yajaira
Published in Nature communications (12.12.2023)
Published in Nature communications (12.12.2023)
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Journal Article
Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids
Ruiz de Gauna, Mikel, Biancaniello, Francesca, González‐Romero, Francisco, Rodrigues, Pedro M., Lapitz, Ainhoa, Gómez‐Santos, Beatriz, Olaizola, Paula, Di Matteo, Sabina, Aurrekoetxea, Igor, Labiano, Ibone, Nieva‐Zuluaga, Ane, Benito‐Vicente, Asier, Perugorria, María J., Apodaka‐Biguri, Maider, Paiva, Nuno A., Sáenz de Urturi, Diego, Buqué, Xabier, Delgado, Igotz, Martín, César, Azkargorta, Mikel, Elortza, Felix, Calvisi, Diego F., Andersen, Jesper B., Alvaro, Domenico, Cardinale, Vincenzo, Bujanda, Luis, Banales, Jesús M., Aspichueta, Patricia
Published in Hepatology (Baltimore, Md.) (01.12.2022)
Published in Hepatology (Baltimore, Md.) (01.12.2022)
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Journal Article
Liver osteopontin is required to prevent the progression of age‐related nonalcoholic fatty liver disease
Gómez‐Santos, Beatriz, Saenz de Urturi, Diego, Nuñez‐García, Maitane, Gonzalez‐Romero, Francisco, Buque, Xabier, Aurrekoetxea, Igor, Gutiérrez de Juan, Virginia, Gonzalez‐Rellan, Maria J., García‐Monzón, Carmelo, González‐Rodríguez, Águeda, Mosteiro, Lorena, Errazti, Gaizka, Mifsut, Patricia, Gaztambide, Sonia, Castaño, Luis, Martin, Cesar, Nogueiras, Rubén, Martinez‐Chantar, María L., Syn, Wing‐Kin, Aspichueta, Patricia
Published in Aging cell (01.08.2020)
Published in Aging cell (01.08.2020)
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Journal Article
Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis
Serrano-Maciá, Marina, Simón, Jorge, González-Rellan, Maria J., Azkargorta, Mikel, Goikoetxea-Usandizaga, Naroa, Lopitz-Otsoa, Fernando, De Urturi, Diego Saenz, Rodríguez-Agudo, Rubén, Lachiondo-Ortega, Sofia, Mercado-Gomez, Maria, Gutiérrez de Juan, Virginia, Bizkarguenaga, Maider, Fernández-Ramos, David, Buque, Xabier, Baselli, Guido A., Valenti, Luca V.C., Iruzubieta, Paula, Crespo, Javier, Villa, Erica, Banales, Jesus M., Avila, Matias A., Marin, Jose J.G., Aspichueta, Patricia, Sutherland, James, Barrio, Rosa, Mayor, Ugo, Elortza, Félix, Xirodimas, Dimitris P., Nogueiras, Rubén, Delgado, Teresa C., Martínez-Chantar, María Luz
Published in Molecular metabolism (Germany) (01.11.2021)
Published in Molecular metabolism (Germany) (01.11.2021)
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Journal Article
Mineralocorticoid receptor modulation by dietary sodium influences NAFLD development in mice
Cabrera, Daniel, Rao, Isabel, Raasch, Fabiola, Solis, Nancy, Pizarro, Margarita, Freire, Mariela, Sáenz De Urturi, Diego, Ramírez, Carolina A., Triantafilo, Nicolás, León, Jonathan, Riquelme, Arnoldo, Barrera, Francisco, Baudrand, Rene, Aspichueta, Patricia, Arrese, Marco, Arab, Juan P.
Published in Annals of hepatology (01.09.2021)
Published in Annals of hepatology (01.09.2021)
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Journal Article
E2F1 and E2F2-mediated repression of CPT2 establishes a lipid-rich tumor-promoting environment
Gonzalez-Romero, Francisco, Mestre, Daniela, Aurrekoetxea, Igor, O'Rourke, Colm J, Andersen, Jesper B, Woodhoo, Ashwin, Tamayo-Caro, Miguel, Varela Rey, Marta, Palomo-Irigoyen, Marta, Gómez-Santos, Beatriz, Sáenz de Urturi, Diego, Núñez-García, Maitane, García-Rodríguez, Juan L, Fernández-Ares, Larraitz, Buqué, Xabier, Iglesias-Ara, Ainhoa, Bernales, Irantzu, Gutierrez De Juan, Virginia, Delgado, Teresa C, Goikoetxea-Usandizaga, Naroa, Lee, Richard, Bhanot, Sanjay, Delgado, Igotz, Perugorria, Maria J, Errazti, Gaizka, Mosteiro, Lorena, Gaztambide, Sonia, Martinez de la Piscina, Idoia, Iruzubieta, Paula, Crespo, Javier, Banales, Jesus M, Martínez-Chantar, María L, Castaño, Luis, Zubiaga, Ana M, Aspichueta, Patricia
Published in Cancer research (Chicago, Ill.) (01.06.2021)
Published in Cancer research (Chicago, Ill.) (01.06.2021)
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Journal Article
Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH
Simón, Jorge, Goikoetxea-Usandizaga, Naroa, Serrano-Maciá, Marina, Fernández-Ramos, David, Sáenz de Urturi, Diego, Gruskos, Jessica J., Fernández-Tussy, Pablo, Lachiondo-Ortega, Sofía, González-Recio, Irene, Rodríguez-Agudo, Rubén, Gutiérrez-de-Juan, Virginia, Rodríguez-Iruretagoyena, Begoña, Varela-Rey, Marta, Gimenez-Mascarell, Paula, Mercado-Gomez, María, Gómez-Santos, Beatriz, Fernandez-Rodriguez, Carmen, Lopitz-Otsoa, Fernando, Bizkarguenaga, Maider, Dames, Sibylle, Schaeper, Ute, Martin, Franz, Sabio, Guadalupe, Iruzubieta, Paula, Crespo, Javier, Aspichueta, Patricia, Chu, Kevan H.-Y., Buccella, Daniela, Martín, César, Delgado, Teresa Cardoso, Martínez-Cruz, Luis Alfonso, Martínez-Chantar, María Luz
Published in Journal of hepatology (01.07.2021)
Published in Journal of hepatology (01.07.2021)
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Journal Article
Abstract 129: Hypercholesterolemia-induced Lxr Signaling In Smc Contributes To Atherosclerotic Lesion Remodeling And Regulates Vascular And Visceral Smc Function
Zhang, Hanming, Biwer, Lauren, Saenz de Urturi, Diego, Fernandez-Tussy, Pablo, Jovin, Daniel, Huang, Yan, Zhang, Xinbo, Esplugues, Enric, Greif, Daniel, Suarez, Yajaira, Fernandez-Hernando, Carlos F
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2024)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2024)
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Journal Article
In Vivo Hepatic Triglyceride Secretion Rate in Antisense Oligonucleotide (ASO)-Treated Mice
Gomez-Santos, Beatriz, Saenz de Urturi, Diego, Buqué, Xabier, Aurrekoetxea, Igor, Nieva, Ane, Fernández-Puertas, Idoia, Aspichueta, Patricia
Published in Methods in molecular biology (Clifton, N.J.) (2023)
Published in Methods in molecular biology (Clifton, N.J.) (2023)
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Journal Article
The DNA damage response is involved in the metabolic dysregulation of MAFLD patients via inefficient fatty acid oxidation
Santos, Beatriz Gómez, Fernámdez-Puertas, Idoia, Nieva-Zuluaga, Ane, de Gauna, Mikel Ruiz, Apodaka-Biguri, Maider, González-Romero, Francisco, de Urturi, Diego Saenz, Delgado, Igotz, Aurrekoetxea, Igor, González, Lorena Mosteiro, Olartekoetxea, Gaizka Errazti, Gaztambide, Sonia, Castaño González, Luis A, Bujanda, Luis, Banales, Jesus Maria, Zubiaga, Ana, Buque, Xabier, Aspichueta, Patricia
Published in Journal of hepatology (01.07.2022)
Published in Journal of hepatology (01.07.2022)
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Journal Article
The uptake of extracellular lipids promotes cholangiocarcinoma progression
de Gauna, Mikel Ruiz, Biancaniello, Francesca, González-Romero, Francisco, Rodrigues, Pedro Miguel, Lapitz, Ainhoa, Santos, Beatriz Gómez, Olaizola, Paula, Di Matteo, Sabina, Aurrekoetxea, Igor, Labiano, Ibone, Nieva-Zuluaga, Ane, Benito-Vicente, Asier, Perugorria, María Jesús, Apodaka-Biguri, Maider, Paiva, Nuno, de Urturi, Diego Saenz, Buque, Xabier, Delgado, Igotz, Martín, Cesar Augusto, Azkargorta, Mikel, Elortza, Felix, Calvisi, Diego, Andersen, Jesper, Alvaro, Domenico, Cardinale, Vincenzo, Bujanda, Luis, Banales, Jesus Maria, Aspichueta, Patricia
Published in Journal of hepatology (01.07.2022)
Published in Journal of hepatology (01.07.2022)
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Journal Article
Methionine adenosyltransferase 1a antisense oligonucleotides induce the fibroblast growth factor 21-driven recovery from obesity and associated hepatoesteatosis
Buque, Xabier, de Urturi, Diego Saenz, Porteiro, Begoña, Folgueira, Cintia, Mora, Alfonso, Delgado, Teresa Cardoso, Prieto-Fernández, Endika, Olaizola, Paula, Santos, Beatriz Gómez, Apodaka-Biguri, Maider, Gonzalez-Romero, Francisco, Nieva-Zuluaga, Ane, de Gauna, Mikel Ruiz, Goikoetxea, Naroa, García Rodríguez, Juan Luis, de Juan, Virginia Gutiérrez, Aurrekoetxea, Igor, Montalvo-Romeral, Valle, Novoa, Eva, Martin-Guerrero, Idoia, Varela-Rey, Marta, Bhanot, Sanjay, Lee, Richard, Banales, Jesus Maria, Syn, Wing-Kin, Sabio, Guadalupe, Martínez-Chantar, María Luz, Nogueiras, Ruben, Aspichueta, Patricia
Published in Journal of hepatology (01.07.2022)
Published in Journal of hepatology (01.07.2022)
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Journal Article
FRI-094-Targeting NEDDylation protects liver from acute drug-induced damage
Simón, Jorge, Ramos, David Fernández, de Juan, Virginia Gutiérrez, Serrano-Macia, Marina, Goikoetxea, Naroa, Urturi, Diego Saenz de, Agudo, Rubén Rodríguez, Otsoa, Fernando Lopitz, de Davalillo, Sergio López, Buque, Xabier, Varela-Rey, Marta, Fernández-Tussy, Pablo, Aspichueta, Patricia, Delgado, Teresa Cardoso, Martínez-Chantar, María Luz
Published in Journal of hepatology (01.04.2019)
Published in Journal of hepatology (01.04.2019)
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Journal Article
FRI-353-Metabolic implications of methionine adenosyltransferase 1A depletion during fasting
Ramos, David Fernández, Mosca, Laura, Goikoetxea, Naroa, Serrano-Macia, Marina, Delgado, Teresa Cardoso, Otsoa, Fernando Lopitz, de Juan, Virginia Gutiérrez, Urturi, Diego Saenz de, Gonzalez-Romero, Francisco, Ruiz-Nuñez, Asier, Falcon-Perez, Juan, Woodhoo, Ashwin, Apichueta, Patricia, Lu, Shelly C., Mato, José M., Martínez-Chantar, María Luz, Varela-Rey, Marta
Published in Journal of hepatology (01.04.2019)
Published in Journal of hepatology (01.04.2019)
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Journal Article
FRI-343-NEDDylation inhibition as a new potential therapy of non-alcoholic fatty liver disease
Serrano-Macia, Marina, Azkargorta, Mikel, Simón, Jorge, Otsoa, Fernando Lopitz, Delgado, Teresa Cardoso, Ramos, David Fernández, de Juan, Virginia Gutiérrez, Varela-Rey, Marta, Goikoetxea, Naroa, Tussy, Pablo Fernández, Apichueta, Patricia, Urturi, Diego Saenz de, Buque, Xabier, Iruzubieta, Paula, Crespo, Javier, Lu, Shelly C., Mato, José M., Elortza, Felix, Martínez-Chantar, María Luz
Published in Journal of hepatology (01.04.2019)
Published in Journal of hepatology (01.04.2019)
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Journal Article
PS-034-MCJ: A therapeutic target in hepatic ischemia and reperfusion injury
Goikoetxea, Naroa, Ramos, David Fernández, Serrano-Macia, Marina, Cornide, Maria Eugenia, Jiménez-Castro, Mónica, Alfano, Bennedetta, Urturi, Diego Saenz de, Gonzalez-Romero, Francisco, de Juan, Virginia Gutiérrez, Iruretagoyena, Begoña Rodriguez, Delgado, Teresa Cardoso, Otsoa, Fernando Lopitz, Torres, Lucía Barbier, Tussy, Pablo Fernández, Simón, Jorge, Martín, Paloma, Anguita, Juan, Redondo, Marina Perez, Miñambres, Eduardo, Lu, Shelly C., Mato, José M., Sabio, Guadalupe, Peralta, Carmen, Aspichueta, Patricia, Casado, Marta, Martin, Cesar, Varela-Rey, Marta, Martínez-Chantar, María Luz
Published in Journal of hepatology (01.04.2019)
Published in Journal of hepatology (01.04.2019)
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Journal Article
PS-008-E2F2 mediated repression of fatty acid B-oxidation is mitigated through CREB1 in progressive non-alcoholic fatty liver disease
Gonzalez-Romero, Francisco, Mestre, Daniela, Aurrekoetxea, Igor, Urturi, Diego Sáenz de, Gomez-Santos, Beatriz, Nuñez-García, Maitane, Buqué, Xabier, Delgado, Igotz, Palomo-Irigoyen, Marta, Tamayo-Caro, Miguel, Woodhoo, Ashwin, Varela-Rey, Marta, Martínez-Chantar, María Luz, Iglesias, Ainhoa, Lee, Richard, Bhanot, Sanjay, Zubiaga, Ana, Aspichueta, Patricia
Published in Journal of hepatology (01.04.2019)
Published in Journal of hepatology (01.04.2019)
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Journal Article
NOVEL TARGET TO TREAT A METABOLIC DISEASE IN AN INDIVIDUAL
SÁENZ DE URTURI, Diego, BUQUÉ GARCÍA, Xabier, ASPICHUETA CELAÁ, Patricia
Year of Publication 21.04.2022
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Year of Publication 21.04.2022
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