Negative inotropic mechanisms of β-cardiotoxin in cardiomyocytes by depression of myofilament ATPase activity without activation of the classical β-adrenergic pathway
Lertwanakarn, Tuchakorn, Suntravat, Montamas, Sánchez, Elda E., Wolska, Beata M., Solaro, R. John, de Tombe, Pieter P., Tachampa, Kittipong
Published in Scientific reports (27.10.2021)
Published in Scientific reports (27.10.2021)
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Titin strain contributes to the Frank–Starling law of the heart by structural rearrangements of both thin- and thick-filament proteins
Ait-Mou, Younss, Hsu, Karen, Farman, Gerrie P., Kumar, Mohit, Greaser, Marion L., Irving, Thomas C., de Tombe, Pieter P.
Published in Proceedings of the National Academy of Sciences - PNAS (23.02.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (23.02.2016)
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Suppression of cardiomyocyte functions by β-CTX isolated from the Thai king cobra ( Ophiophagus hannah ) venom via an alternative method
Lertwanakarn, Tuchakorn, Suntravat, Montamas, Sanchez, Elda E, Boonhoh, Worakan, Solaro, R John, Wolska, Beata M, Martin, Jody L, de Tombe, Pieter P, Tachampa, Kittipong
Published in The journal of venomous animals and toxins including tropical diseases (2020)
Published in The journal of venomous animals and toxins including tropical diseases (2020)
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Length-dependent activation in three striated muscle types of the rat
Konhilas, John P., Irving, Thomas C., Tombe, Pieter P.
Published in The Journal of physiology (01.10.2002)
Published in The Journal of physiology (01.10.2002)
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Cardiac resynchronization sensitizes the sarcomere to calcium by reactivating GSK-3β
Kirk, Jonathan A, Holewinski, Ronald J, Kooij, Viola, Agnetti, Giulio, Tunin, Richard S, Witayavanitkul, Namthip, de Tombe, Pieter P, Gao, Wei Dong, Van Eyk, Jennifer, Kass, David A
Published in The Journal of clinical investigation (01.01.2014)
Published in The Journal of clinical investigation (01.01.2014)
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Skeletal myosin binding protein-C isoforms regulate thin filament activity in a Ca2+-dependent manner
Lin, Brian Leei, Li, Amy, Mun, Ji Young, Previs, Michael J., Previs, Samantha Beck, Campbell, Stuart G., dos Remedios, Cristobal G., Tombe, Pieter de P., Craig, Roger, Warshaw, David M., Sadayappan, Sakthivel
Published in Scientific reports (08.02.2018)
Published in Scientific reports (08.02.2018)
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R-CEPIA1er as a new tool to directly measure sarcoplasmic reticulum [Ca] in ventricular myocytes
Bovo, Elisa, Martin, Jody L, Tyryfter, Jollyn, de Tombe, Pieter P, Zima, Aleksey V
Published in American journal of physiology. Heart and circulatory physiology (01.07.2016)
Published in American journal of physiology. Heart and circulatory physiology (01.07.2016)
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Truncation of the N-terminus of cardiac troponin I initiates adaptive remodeling of the myocardial proteosome via phosphorylation of mechano-sensitive signaling pathways
Warren, Chad M., Halas, Monika, Goldspink, Paul H., Feng, Han-Zhong, Herren, Anthony W., Wolska, Beata M., de Tombe, Pieter P., Jin, Jian-Ping, Solaro, R. John
Published in Molecular and cellular biochemistry (01.06.2022)
Published in Molecular and cellular biochemistry (01.06.2022)
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Myosin light chain phosphorylation to the rescue
Granzier, Henk L., de Tombe, Pieter P.
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2015)
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Myosin head orientation: a structural determinant for the Frank-Starling relationship
Farman, Gerrie P, Gore, David, Allen, Edward, Schoenfelt, Kelly, Irving, Thomas C, de Tombe, Pieter P
Published in American journal of physiology. Heart and circulatory physiology (01.06.2011)
Published in American journal of physiology. Heart and circulatory physiology (01.06.2011)
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Journal Article
Ablation of Ventricular Myosin Regulatory Light Chain Phosphorylation in Mice Causes Cardiac Dysfunction in Situ and Affects Neighboring Myofilament Protein Phosphorylation
Scruggs, Sarah B., Hinken, Aaron C., Thawornkaiwong, Ariyaporn, Robbins, Jeffrey, Walker, Lori A., de Tombe, Pieter P., Geenen, David L., Buttrick, Peter M., Solaro, R. John
Published in The Journal of biological chemistry (20.02.2009)
Published in The Journal of biological chemistry (20.02.2009)
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Blebbistatin: use as inhibitor of muscle contraction
Farman, Gerrie P., Tachampa, Kittipong, Mateja, Ryan, Cazorla, Olivier, Lacampagne, Alain, de Tombe, Pieter P.
Published in Pflügers Archiv (01.03.2008)
Published in Pflügers Archiv (01.03.2008)
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Titin isoform switch in ischemic human heart disease
NEAGOE, Ciprian, KULKE, Michael, DEL MONTE, Federica, GWATHMEY, Judith K, DE TOMBE, Pieter P, HAJJAR, Roger J, LINKE, Wolfgang A
Published in Circulation (New York, N.Y.) (10.09.2002)
Published in Circulation (New York, N.Y.) (10.09.2002)
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