Acute promyelocytic leukemia, arsenic, and PML bodies
de Thé, Hugues, Le Bras, Morgane, Lallemand-Breitenbach, Valérie
Published in The Journal of cell biology (09.07.2012)
Published in The Journal of cell biology (09.07.2012)
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Journal Article
Resistance to Therapy in Acute Promyelocytic Leukemia
Lehmann-Che, Jacqueline, Bally, Cecile, de Thé, Hugues
Published in The New England journal of medicine (18.09.2014)
Published in The New England journal of medicine (18.09.2014)
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Journal Article
Oxidative stress-induced assembly of PML nuclear bodies controls sumoylation of partner proteins
Sahin, Umut, Ferhi, Omar, Jeanne, Marion, Benhenda, Shirine, Berthier, Caroline, Jollivet, Florence, Niwa-Kawakita, Michiko, Faklaris, Orestis, Setterblad, Niclas, de Thé, Hugues, Lallemand-Breitenbach, Valérie
Published in The Journal of cell biology (17.03.2014)
Published in The Journal of cell biology (17.03.2014)
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Journal Article
PML is a ROS sensor activating p53 upon oxidative stress
Niwa-Kawakita, Michiko, Ferhi, Omar, Soilihi, Hassane, Le Bras, Morgane, Lallemand-Breitenbach, Valérie, de Thé, Hugues
Published in The Journal of experimental medicine (06.11.2017)
Published in The Journal of experimental medicine (06.11.2017)
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Journal Article
Curing APL through PML/RARA degradation by As2O3
Lallemand-Breitenbach, Valerie, Zhu, Jun, Chen, Zhu, de Thé, Hugues
Published in Trends in molecular medicine (01.01.2012)
Published in Trends in molecular medicine (01.01.2012)
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Journal Article
RING tetramerization is required for nuclear body biogenesis and PML sumoylation
Wang, Pengran, Benhenda, Shirine, Wu, Haiyan, Lallemand-Breitenbach, Valérie, Zhen, Tao, Jollivet, Florence, Peres, Laurent, Li, Yuwen, Chen, Sai-Juan, Chen, Zhu, de Thé, Hugues, Meng, Guoyu
Published in Nature communications (29.03.2018)
Published in Nature communications (29.03.2018)
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Journal Article
PML/RARA oxidation and arsenic binding initiate the antileukemia response of As2O3
Jeanne, Marion, Lallemand-Breitenbach, Valérie, Ferhi, Omar, Koken, Marcel, Le Bras, Morgane, Duffort, Stéphanie, Peres, Laurent, Berthier, Caroline, Soilihi, Hassane, Raught, Brian, de Thé, Hugues
Published in Cancer cell (13.07.2010)
Published in Cancer cell (13.07.2010)
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Journal Article
TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy
Yang, Rui Meng, Tao, Jiong, Zhan, Ming, Yuan, Hao, Wang, Hai Hong, Chen, Sai Juan, Chen, Zhu, de Thé, Hugues, Zhou, Jun, Guo, Ying, Zhu, Jun
Published in Cell death and differentiation (01.11.2019)
Published in Cell death and differentiation (01.11.2019)
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Journal Article
Characterization of a Large Panel of Patient-Derived Tumor Xenografts Representing the Clinical Heterogeneity of Human Colorectal Cancer
JULIEN, Sylvia, MERINO-TRIGO, Ana, WEISWALD, Louis-Bastien, LANTUAS, Denis, MORGAND, Loïc, PHAM, Emmanuel, GONIN, Patrick, DANGLES-MARIE, Virginie, JOB, Bastien, DESSEN, Philippe, BRUNO, Alain, PIERRE, Alain, LACROIX, Ludovic, DE THE, Hugues, SOLIMAN, Hany, NUNES, Manoel, LARDIER, Guillaume, CALVET, Loreley, DEMERS, Brigitte, PREVOST, Gregoire, VRIGNAUD, Patricia, ROMAN-ROMAN, Sergio, DUCHAMP, Olivier, POCARD, Marc, BERTHET, Cyril, GOERE, Diane, MARIANI, Pascale, LANDRON, Sophie, BIGOT, Ludovic, NEMATI, Fariba, DARTIGUES, Peggy
Published in Clinical cancer research (01.10.2012)
Published in Clinical cancer research (01.10.2012)
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Journal Article
Arsenic Trioxide Controls the Fate of the PML-RARα Oncoprotein by Directly Binding PML
Zhang, Xiao-Wei, Yan, Xiao-Jing, Zhou, Zi-Ren, Yang, Fei-Fei, Wu, Zi-Yu, Sun, Hong-Bin, Liang, Wen-Xue, Song, Ai-Xin, Lallemand-Breitenbach, Valerie, Jeanne, Marion, Zhang, Qun-Ye, Yang, Huai-Yu, Huang, Qiu-Hua, Zhou, Guang-Biao, Tong, Jian-Hua, Zhang, Yan, Wu, Ji-Hui, Hu, Hong-Yu, de Thé, Hugues, Chen, Sai-Juan, Chen, Zhu
Published in Science (American Association for the Advancement of Science) (09.04.2010)
Published in Science (American Association for the Advancement of Science) (09.04.2010)
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Journal Article
Sumoylation in Physiology, Pathology and Therapy
Sahin, Umut, de Thé, Hugues, Lallemand-Breitenbach, Valérie
Published in Cells (Basel, Switzerland) (26.02.2022)
Published in Cells (Basel, Switzerland) (26.02.2022)
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Journal Article
Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells
El Hajj, Hiba, Dassouki, Zeina, Berthier, Caroline, Raffoux, Emmanuel, Ades, Lionel, Legrand, Olivier, Hleihel, Rita, Sahin, Umut, Tawil, Nadim, Salameh, Ala, Zibara, Kazem, Darwiche, Nadine, Mohty, Mohamad, Dombret, Hervé, Fenaux, Pierre, de Thé, Hugues, Bazarbachi, Ali
Published in Blood (28.05.2015)
Published in Blood (28.05.2015)
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Journal Article
Co-targeting leukemia-initiating cells and leukemia bulk leads to disease eradication
Moretti, Simona, Abdel-Aziz, Amal Kamal, Ceccacci, Elena, Pallavicini, Isabella, Santoro, Fabio, de Thé, Hugues, Minucci, Saverio
Published in Leukemia (01.05.2022)
Published in Leukemia (01.05.2022)
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Journal Article