Partially redundant enhancers cooperatively maintain Mammalian pomc expression above a critical functional threshold
Lam, Daniel D, de Souza, Flavio S J, Nasif, Sofia, Yamashita, Miho, López-Leal, Rodrigo, Otero-Corchon, Veronica, Meece, Kana, Sampath, Harini, Mercer, Aaron J, Wardlaw, Sharon L, Rubinstein, Marcelo, Low, Malcolm J
Published in PLoS genetics (01.02.2015)
Published in PLoS genetics (01.02.2015)
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Journal Article
Obesity-programmed mice are rescued by early genetic intervention
Bumaschny, Viviana F, Yamashita, Miho, Casas-Cordero, Rodrigo, Otero-Corchón, Verónica, de Souza, Flávio S J, Rubinstein, Marcelo, Low, Malcolm J
Published in The Journal of clinical investigation (01.11.2012)
Published in The Journal of clinical investigation (01.11.2012)
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Journal Article
Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors
Brinkmeier, Michelle L, Bando, Hironori, Camarano, Adriana C, Fujio, Shingo, Yoshimoto, Koji, de Souza, Flávio Sj, Camper, Sally A
Published in The Journal of clinical investigation (01.08.2020)
Published in The Journal of clinical investigation (01.08.2020)
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Journal Article
The estrogen receptor α colocalizes with proopiomelanocortin in hypothalamic neurons and binds to a conserved motif present in the neuron-specific enhancer nPE2
de Souza, Flávio S.J., Nasif, Sofia, López-Leal, Rodrigo, Levi, Diego H., Low, Malcolm J., Rubinsten, Marcelo
Published in European journal of pharmacology (11.06.2011)
Published in European journal of pharmacology (11.06.2011)
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Journal Article
Conference Proceeding
Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene
Santangelo, Andrea M, de Souza, Flávio S J, Franchini, Lucía F, Bumaschny, Viviana F, Low, Malcolm J, Rubinstein, Marcelo
Published in PLoS genetics (01.10.2007)
Published in PLoS genetics (01.10.2007)
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The Homeodomain Transcription Factor NKX2.1 Is Essential for the Early Specification of Melanocortin Neuron Identity and Activates Pomc Expression in the Developing Hypothalamus
Orquera, Daniela P, Tavella, M Belén, de Souza, Flavio S J, Nasif, Sofía, Low, Malcolm J, Rubinstein, Marcelo
Published in The Journal of neuroscience (22.05.2019)
Published in The Journal of neuroscience (22.05.2019)
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Journal Article
Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood
Nasif, Sofia, de Souza, Flavio S. J., González, Laura E., Yamashita, Miho, Orquera, Daniela P., Low, Malcolm J., Rubinstein, Marcelo
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.2015)
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Journal Article
Editorial: Transcription Regulation-Brain Development and Homeostasis-A Finely Tuned and Orchestrated Scenario in Physiology and Pathology
Muñoz, Estela M, de Souza, Flavio S J, Rath, Martin F, Martínez Cerdeño, Verónica
Published in Frontiers in molecular neuroscience (14.01.2022)
Published in Frontiers in molecular neuroscience (14.01.2022)
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Journal Article
Selective pressure against horizontally acquired prokaryotic genes as a driving force of plastid evolution
Llorente, Briardo, de Souza, Flavio S. J., Soto, Gabriela, Meyer, Cristian, Alonso, Guillermo D., Flawiá, Mirtha M., Bravo-Almonacid, Fernando, Ayub, Nicolás D., Rodríguez-Concepción, Manuel
Published in Scientific reports (11.01.2016)
Published in Scientific reports (11.01.2016)
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Journal Article
Obesity-programmed mice are rescued by early genetic intervention
Bumaschny, Viviana F, Yamashita, Miho, Casas-Cordero, Rodrigo, Otero-Corchon, Veronica, de Souza, Flavio S.J, Rubinstein, Marcelo, Low, Malcolm J
Published in The Journal of clinical investigation (01.11.2012)
Published in The Journal of clinical investigation (01.11.2012)
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Journal Article
A Transgenic Marker for Newly Born Granule Cells in Dentate Gyrus
Overstreet, Linda S, Hentges, Shane T, Bumaschny, Viviana F, de Souza, Flavio S. J, Smart, James L, Santangelo, Andrea M, Low, Malcolm J, Westbrook, Gary L, Rubinstein, Marcelo
Published in The Journal of neuroscience (31.03.2004)
Published in The Journal of neuroscience (31.03.2004)
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Journal Article
A mammalian tripartite enhancer cluster controls hypothalamic Pomc expression, food intake, and body weight
Rojo, Daniela, Hael, Clara E, Soria, Agustina, de Souza, Flávio S J, Low, Malcolm J, Franchini, Lucía F, Rubinstein, Marcelo
Published in Proceedings of the National Academy of Sciences - PNAS (30.04.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (30.04.2024)
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Constitutive Expression of the α10 Nicotinic Acetylcholine Receptor Subunit Fails to Maintain Cholinergic Responses in Inner Hair Cells After the Onset of Hearing
Taranda, Julián, Ballestero, Jimena A., Hiel, Hakim, Souza, Flavio S. J. de, Wedemeyer, Carolina, Gómez-Casati, M. Eugenia, Lipovsek, Marcela, Vetter, Douglas E., Fuchs, Paul A., Katz, Eleonora, Elgoyhen, A. Belén
Published in Journal of the Association for Research in Otolaryngology (01.09.2009)
Published in Journal of the Association for Research in Otolaryngology (01.09.2009)
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