Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules
Zhou, Guoying, Sprengers, Dave, Mancham, Shanta, Erkens, Remco, Boor, Patrick P.C., van Beek, Adriaan A., Doukas, Michail, Noordam, Lisanne, Campos Carrascosa, Lucia, de Ruiter, Valeska, van Leeuwen, Roelof W.F., Polak, Wojciech G., de Jonge, Jeroen, Groot Koerkamp, Bas, van Rosmalen, Belle, van Gulik, Thomas M., Verheij, Joanne, IJzermans, Jan N.M., Bruno, Marco J., Kwekkeboom, Jaap
Published in Journal of hepatology (01.10.2019)
Published in Journal of hepatology (01.10.2019)
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Systemic T-cell and humoral responses against cancer testis antigens in hepatocellular carcinoma patients
Noordam, Lisanne, de Beijer, Monique T.A., Mancham, Shanta, Vogler, Isabel, Boor, Patrick P.C., de Ruiter, Valeska, Luijten, Robbie, IJzermans, Jan N.M., Sahin, Ugur, Bruno, Marco J., Sprengers, Dave, Buschow, Sonja I., Kwekkeboom, Jaap
Published in Oncoimmunology (31.12.2022)
Published in Oncoimmunology (31.12.2022)
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FcγRIIB engagement drives agonistic activity of Fc-engineered αOX40 antibody to stimulate human tumor-infiltrating T cells
Campos Carrascosa, Lucia, van Beek, Adriaan A, de Ruiter, Valeska, Doukas, Michail, Wei, Jie, Fisher, Timothy S, Ching, Keith, Yang, Wenjing, van Loon, Karlijn, Boor, Patrick P C, Rakké, Yannick S, Noordam, Lisanne, Doornebosch, Pascal, Grünhagen, Dirk, Verhoef, Kees, Polak, Wojciech G, IJzermans, Jan N M, Ni, Irene, Yeung, Yik Andy, Salek-Ardakani, Shahram, Sprengers, Dave, Kwekkeboom, Jaap
Published in Journal for immunotherapy of cancer (01.09.2020)
Published in Journal for immunotherapy of cancer (01.09.2020)
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Modelling immune cytotoxicity for cholangiocarcinoma with tumour-derived organoids and effector T cells
Zhou, Guoying, Lieshout, Ruby, van Tienderen, Gilles S., de Ruiter, Valeska, van Royen, Martin E., Boor, Patrick P. C., Magré, Luc, Desai, Jyaysi, Köten, Kübra, Kan, Yik Yang, Ge, Zhouhong, Campos Carrascosa, Lucia, Geuijen, Cecile, Sprengers, Dave, van der Laan, Luc J. W., Verstegen, Monique M. A., Kwekkeboom, Jaap
Published in British journal of cancer (01.09.2022)
Published in British journal of cancer (01.09.2022)
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An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T-cell Function and Antitumor Immunity
Xu, Yuanming, Carrascosa, Lucia Campos, Yeung, Yik Andy, Chu, Matthew Ling-Hon, Yang, Wenjing, Djuretic, Ivana, Pappas, Danielle C, Zeytounian, John, Ge, Zhouhong, de Ruiter, Valeska, Starbeck-Miller, Gabriel R, Patterson, James, Rigas, Diamanda, Chen, Shih-Hsun, Kraynov, Eugenia, Boor, Patrick P, Noordam, Lisanne, Doukas, Michael, Tsao, Dave, Ijzermans, Jan N, Guo, Jie, Grünhagen, Dirk J, Erdmann, Joris, Verheij, Joanne, van Royen, Martin E, Doornebosch, Pascal G, Feldman, Renny, Park, Terrence, Mahmoudi, Salah, Dorywalska, Magdalena, Ni, Irene, Chin, Sherman M, Mistry, Tina, Mosyak, Lidia, Lin, Laura, Ching, Keith A, Lindquist, Kevin C, Ji, Changhua, Londono, Luz Marina, Kuang, Bing, Rickert, Robert, Kwekkeboom, Jaap, Sprengers, Dave, Huang, Tzu-Hsuan, Chaparro-Riggers, Javier
Published in Cancer immunology research (01.10.2021)
Published in Cancer immunology research (01.10.2021)
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Adjuvant dendritic cell therapy in stage IIIB/C melanoma: the MIND-DC randomized phase III trial
Bol, Kalijn F., Schreibelt, Gerty, Bloemendal, Martine, van Willigen, Wouter W., Hins-de Bree, Simone, de Goede, Anna L., de Boer, Annemiek J., Bos, Kevin J. H., Duiveman-de Boer, Tjitske, Olde Nordkamp, Michel A. M., van Oorschot, Tom G. M., Popelier, Carlijn J., Pots, Jeanne M., Scharenborg, Nicole M., van de Rakt, Mandy W. M. M., de Ruiter, Valeska, van Meeteren, Wilmy S., van Rossum, Michelle M., Croockewit, Sandra J., Koeneman, Bouke J., Creemers, Jeroen H. A., Wortel, Inge M. N., Angerer, Caroline, Brüning, Mareke, Petry, Katja, Dzionek, Andrzej, van der Veldt, Astrid A., van Grünhagen, Dirk J., Werner, Johanna E. M., Bonenkamp, Johannes J., Haanen, John B. A. G., Boers-Sonderen, Marye J., Koornstra, Rutger H. T., Boomsma, Martijn F., Aarntzen, Erik H. J., Gotthardt, Martin, Nagarajah, James, de Witte, Theo J. M., Figdor, Carl G., de Wilt, Johannes H. W., Textor, Johannes, de Groot, Jan Willem B., Gerritsen, Winald R., de Vries, I. Jolanda M.
Published in Nature communications (23.02.2024)
Published in Nature communications (23.02.2024)
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GITR Ligation Improves Anti-PD1-Mediated Restoration of Human MMR-Proficient Colorectal Carcinoma Tumor-Derived T Cells
Rakké, Yannick S., Campos Carrascosa, Lucia, van Beek, Adriaan A., de Ruiter, Valeska, van Gemerden, Rachelle S., Doukas, Michail, Doornebosch, Pascal G., Vermaas, Maarten, ter Borg, Susan, van der Harst, Erwin, Coene, Peter Paul L.O., Kliffen, Mike, Grünhagen, Dirk J., Verhoef, Cornelis, IJzermans, Jan N.M., Kwekkeboom, Jaap, Sprengers, Dave
Published in Cellular and molecular gastroenterology and hepatology (01.01.2023)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2023)
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GITR Ligation Improves Anti-PD1-Mediated Restoration of Human MMR-Proficient Colorectal Carcinoma Tumor-Derived T CellsSummary
Yannick S. Rakké, Lucia Campos Carrascosa, Adriaan A. van Beek, Valeska de Ruiter, Rachelle S. van Gemerden, Michail Doukas, Pascal G. Doornebosch, Maarten Vermaas, Susan ter Borg, Erwin van der Harst, Peter Paul L.O. Coene, Mike Kliffen, Dirk J. Grünhagen, Cornelis Verhoef, Jan N.M. IJzermans, Jaap Kwekkeboom, Dave Sprengers
Published in Cellular and molecular gastroenterology and hepatology (01.01.2023)
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Published in Cellular and molecular gastroenterology and hepatology (01.01.2023)
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588 Targeting GITR enhances human tumour-infiltrating T cell functionality in mismatch repair proficient primary colorectal carcinoma and liver metastases
Rakké, Yannick, Lucia Campos Carrascosa, Adriaan van Beek, de Ruiter, Valeska, Doukas, Michael, Susan ter Borg, Doornebosch, Pascal, Vermaas, Maarten, van der Harst, Erwin, Coene, Peter Paul, Grünhagen, Dirk, Verhoef, Cornelis, IJzermans, Jan, Sprengers, Dave, Kwekkeboom, Jaap
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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