Mechanistic Distinctions between CHK1 and WEE1 Inhibition Guide the Scheduling of Triple Therapy with Gemcitabine
Koh, Siang-Boon, Wallez, Yann, Dunlop, Charles R, Bernaldo de Quirós Fernández, Sandra, Bapiro, Tashinga E, Richards, Frances M, Jodrell, Duncan I
Published in Cancer research (Chicago, Ill.) (01.06.2018)
Published in Cancer research (Chicago, Ill.) (01.06.2018)
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The ATR Inhibitor AZD6738 Synergizes with Gemcitabine In Vitro and In Vivo to Induce Pancreatic Ductal Adenocarcinoma Regression
Wallez, Yann, Dunlop, Charles R, Johnson, Timothy Isaac, Koh, Siang-Boon, Fornari, Chiara, Yates, James W T, Bernaldo de Quirós Fernández, Sandra, Lau, Alan, Richards, Frances M, Jodrell, Duncan I
Published in Molecular cancer therapeutics (01.08.2018)
Published in Molecular cancer therapeutics (01.08.2018)
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Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models
Dunlop, Charles R., Wallez, Yann, Johnson, Timothy Isaac, Bernaldo de Quirós Fernández, Sandra, Durant, Stephen T., Cadogan, Elaine B., Lau, Alan, Richards, Frances M., Jodrell, Duncan I.
Published in British journal of cancer (27.10.2020)
Published in British journal of cancer (27.10.2020)
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MAX Mutations Cause Hereditary and Sporadic Pheochromocytoma and Paraganglioma
BURNICHON, Nelly, CASCON, Alberto, DE QUIROS, Sandra Bernaldo, BERTHERAT, Jerome, BIGNON, Yves-Jean, BLOK, Marinus J, BOBISSE, Sara, BORREGO, Salud, CASTELLANO, Maurizio, CHANSON, Philippe, CHIARA, Maria-Dolores, CORSSMIT, Eleonora P. M, SCHIAVI, Francesca, GIACCHE, Mara, DE KRIJGER, Ronald R, ERCOLINO, Tonino, GIRERD, Xavier, GOMEZ-GARCIA, Encarna B, GOMEZ-GRANA, Alvaro, GUILHEM, Isabelle, HES, Frederik J, HONRADO, Emiliano, KORPERSHOEK, Esther, PAES MORALES, Nicole, LENDERS, Jacques W. M, LETON, Rocio, MENSENKAMP, Arjen R, MERLO, Anna, MORI, Luigi, MURAT, Arnaud, PIERRE, Peggy, PLOUIN, Pierre-François, PRODANOV, Tamara, QUESADA-CHARNECO, Miguel, COMINO-MENDEZ, Iñaki, NANQIN, RAPIZZI, Elena, RAYMOND, Victoria, REISCH, Nicole, RONCADOR, Giovanna, RUIZ-FERRER, Macarena, SCHILLO, Frank, STEGMANN, Alexander P. A, SUAREZ, Carlos, TASCHIN, Elisa, ABERMIL, Nasséra, TIMMERS, Henri J. L. M, TOPS, Carli M. J, URIOSTE, Miguel, BEUSCHLEIN, Felix, PACAK, Karel, MANNELLI, Massimo, DAHIA, Patricia L. M, OPOCHER, Giuseppe, EISENHOFER, Graeme, GIMENEZ-ROQUEPLO, Anne-Paule, INGLADA-PEREZ, Lucia, DE CUBAS, Aguirre A, AMAR, Laurence, BARONTINI, Marta
Published in Clinical cancer research (15.05.2012)
Published in Clinical cancer research (15.05.2012)
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A Highly Porous Metal-Organic Framework System to Deliver Payloads for Gene Knockdown
Teplensky, Michelle H., Fantham, Marcus, Poudel, Chetan, Hockings, Colin, Lu, Meng, Guna, Alina, Aragones-Anglada, Marta, Moghadam, Peyman Z., Li, Peng, Farha, Omar K., Bernaldo de Quirós Fernández, Sandra, Richards, Frances M., Jodrell, Duncan I., Kaminski Schierle, Gabriele, Kaminski, Clemens F., Fairen-Jimenez, David
Published in Chem (14.11.2019)
Published in Chem (14.11.2019)
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Ataxia Telangiectasia Mutated and its value as a predictive biomarker of response to AZD6738 therapy in pancreatic cancer
Dunlop, Charles R., Wallez, Yann, Bernaldo de Quirós Fernández, Sandra, Lau, Alan, Richards, Frances M., Jodrell, Duncan I.
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.12.2020)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.12.2020)
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Quantifying cell cycle-dependent drug sensitivities in cancer using a high throughput synchronisation and screening approach
Johnson, Timothy I., Minteer, Christopher J., Kottmann, Daniel, Dunlop, Charles R., Fernández, Sandra Bernaldo de Quirós, Carnevalli, Larissa S., Wallez, Yann, Lau, Alan, Richards, Frances M., Jodrell, Duncan I.
Published in EBioMedicine (01.06.2021)
Published in EBioMedicine (01.06.2021)
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Identification of Somatic VHL Gene Mutations in Sporadic Head and Neck Paragangliomas in Association With Activation of the HIF-1α/miR-210 Signaling Pathway
Merlo, Anna, de Quirós, Sandra Bernaldo, de Santa-María, Inés Sáenz, Pitiot, Ana S, Balbín, Milagros, Astudillo, Aurora, Scola, Bartolomé, Arístegui, Miguel, Quer, Miquel, Suarez, Carlos, Chiara, María-Dolores
Published in The journal of clinical endocrinology and metabolism (01.10.2013)
Published in The journal of clinical endocrinology and metabolism (01.10.2013)
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A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes
de la Rosa, Jorge, Weber, Julia, Friedrich, Mathias Josef, Li, Yilong, Rad, Lena, Ponstingl, Hannes, Liang, Qi, de Quirós, Sandra Bernaldo, Noorani, Imran, Metzakopian, Emmanouil, Strong, Alexander, Li, Meng Amy, Astudillo, Aurora, Fernández-García, María Teresa, Fernández-García, María Soledad, Hoffman, Gary J, Fuente, Rocío, Vassiliou, George S, Rad, Roland, López-Otín, Carlos, Bradley, Allan, Cadiñanos, Juan
Published in Nature genetics (01.05.2017)
Published in Nature genetics (01.05.2017)
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A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes
de la Rosa, Jorge, Weber, Julia, Friedrich, Mathias Josef, Li, Yilong, Rad, Lena, Ponstingl, Hannes, Liang, Qi, de Quirós, Sandra Bernaldo, Noorani, Imran, Metzakopian, Emmanouil, Strong, Alexander, Li, Meng Amy, Astudillo, Aurora, Fernández-García, María Teresa, Fernández-García, María Soledad, Hoffman, Gary J, Fuente, Rocío, Vassiliou, George S, Rad, Roland, López-Otín, Carlos, Bradley, Allan, Cadiñanos, Juan
Published in Nature genetics (01.05.2017)
Published in Nature genetics (01.05.2017)
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Identification of a Signaling Axis HIF-1α/MicroRNA-210/ISCU Independent of SDH Mutation That Defines a Subgroup of Head and Neck Paragangliomas
Merlo, Anna, de Quiros, Sandra Bernaldo, Secades, Pablo, Zambrano, Iriana, Balbín, Milagros, Astudillo, Aurora, Scola, Bartolomé, Arístegui, Miguel, Suarez, Carlos, Chiara, María-Dolores
Published in The journal of clinical endocrinology and metabolism (01.11.2012)
Published in The journal of clinical endocrinology and metabolism (01.11.2012)
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Identification of TRPC6 as a possible candidate target gene within an amplicon at 11q21-q22.2 for migratory capacity in head and neck squamous cell carcinomas
Bernaldo de Quirós, Sandra, Merlo, Anna, Secades, Pablo, Zambrano, Iriana, de Santa María, Ines Saenz, Ugidos, Nerea, Jantus-Lewintre, Eloisa, Sirera, Rafael, Suarez, Carlos, Chiara, María-Dolores
Published in BMC cancer (14.03.2013)
Published in BMC cancer (14.03.2013)
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Abstract 271: The role of ATM and DNA-PK in responding to AZD6738-induced damage in pancreatic ductal adenocarcinoma cells
Dunlop, Charles R., Wallez, Yann, Fernández, Sandra Bernaldo de Quirós, Karim, Saadia A., Lau, Alan, Richards, Frances M., Jodrell, Duncan I.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Clinically relevant HIF-1α-dependent metabolic reprogramming in oropharyngeal squamous cell carcinomas includes coordinated activation of CAIX and the miR-210/ISCU signaling axis, but not MCT1 and MCT4 upregulation
Sáenz-de-Santa-María, Inés, Bernardo-Castiñeira, Cristóbal, Secades, Pablo, Bernaldo-de-Quirós, Sandra, Rodrigo, Juan Pablo, Astudillo, Aurora, Chiara, María-Dolores
Published in Oncotarget (21.02.2017)
Published in Oncotarget (21.02.2017)
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