Privileged Structures in the design of Potential Drug Candidates for Neglected Diseases
Leite, Ana Cristina Lima, Espíndola, José Wanderlan Pontes, de Oliveira Cardoso, Marcos Veríssimo, de Oliveira Filho, Gevanio Bezerra
Published in Current medicinal chemistry (01.01.2019)
Published in Current medicinal chemistry (01.01.2019)
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1,3-Thiazole derivatives as privileged structures for anti-Trypanosoma cruzi activity: Rational design, synthesis, in silico and in vitro studies
Cox Holanda de Barros Dias, Mabilly, Souza Barbalho, Mayara, Bezerra de Oliveira Filho, Gevanio, Veríssimo de Oliveira Cardoso, Marcos, Lima Leite, Ana Cristina, da Silva Santos, Aline Caroline, Cristovão Silva, Ana Catarina, Accioly Brelaz de Castro, Maria Carolina, Maria Nascimento Moura, Danielle, Gomes Rebello Ferreira, Luiz Felipe, Zaldini Hernandes, Marcelo, de Freitas e Silva, Rafael, Rêgo Alves Pereira, Valéria
Published in European journal of medicinal chemistry (05.09.2023)
Published in European journal of medicinal chemistry (05.09.2023)
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Synthesis and structure–activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain
Espíndola, José Wanderlan Pontes, Cardoso, Marcos Veríssimo de Oliveira, Filho, Gevanio Bezerra de Oliveira, Oliveira e Silva, Dayane Albuquerque, Moreira, Diogo Rodrigo Magalhaes, Bastos, Tanira Matutino, Simone, Carlos Alberto de, Soares, Milena Botelho Pereira, Villela, Filipe Silva, Ferreira, Rafaela Salgado, Castro, Maria Carolina Accioly Brelaz de, Pereira, Valéria Rego Alves, Murta, Silvane Maria Fonseca, Sales Junior, Policarpo Ademar, Romanha, Alvaro José, Leite, Ana Cristina Lima
Published in European journal of medicinal chemistry (28.08.2015)
Published in European journal of medicinal chemistry (28.08.2015)
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Structural design, synthesis and pharmacological evaluation of 4-thiazolidinones against Trypanosoma cruzi
de Oliveira Filho, Gevanio Bezerra, de Oliveira Cardoso, Marcos Veríssimo, Espíndola, José Wanderlan Pontes, Ferreira, Luiz Felipe Gomes Rebello, de Simone, Carlos Alberto, Ferreira, Rafaela Salgado, Coelho, Pollyanne Lacerda, Meira, Cássio Santana, Magalhaes Moreira, Diogo Rodrigo, Soares, Milena Botelho Pereira, Lima Leite, Ana Cristina
Published in Bioorganic & medicinal chemistry (01.12.2015)
Published in Bioorganic & medicinal chemistry (01.12.2015)
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Structural design, synthesis and anti-Trypanosoma cruzi profile of the second generation of 4-thiazolidinones chlorine derivatives
Bezerra de Oliveira Filho, Gevanio, Veríssimo de Oliveira Cardoso, Marcos, Caroline da Silva Santos, Aline, Ramos dos Santos, Thiago André, Cristovão-Silva, Ana Catarina, Rubio, Laura González, da Silva Maia Neto, Luiz, Leite, Paulo Gaio, Machado, Fabiana Simão, Alves, Luiz Carlos, Brayner, Fabio André, Alves Pereira, Valéria Rêgo, Lima Leite, Ana Cristina
Published in Chemico-biological interactions (25.08.2021)
Published in Chemico-biological interactions (25.08.2021)
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2-(phenylthio)ethylidene derivatives as anti-Trypanosoma cruzi compounds: Structural design, synthesis and antiparasitic activity
Cardoso, Marcos Veríssimo de Oliveira, Oliveira Filho, Gevanio Bezerra de, Siqueira, Lucianna Rabelo Pessoa de, Espíndola, José Wanderlan Pontes, Silva, Elany Barbosa da, Mendes, Andresa Pereira de Oliveira, Pereira, Valéria Rêgo Alves, Castro, Maria Carolina Accioly Brelaz de, Ferreira, Rafaela Salgado, Villela, Filipe Silva, Costa, Francielly Morais Rodrigues da, Meira, Cássio Santana, Moreira, Diogo Rodrigo Magalhães, Soares, Milena Botelho Pereira, Leite, Ana Cristina Lima
Published in European journal of medicinal chemistry (15.10.2019)
Published in European journal of medicinal chemistry (15.10.2019)
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Cytotoxic and toxicological effects of phthalimide derivatives on tumor and normal murine cells
Ferreira, Paulo Michel Pinheiro, Da Costa, Patricia Marçal, Costa, Arinice de Menezes, Lima, Daisy Jereissati Barbosa, Drumond, Renata Rosado, Silva, Jurandy do Nascimento, Moreira, Diogo Rodrigo de Magalhães, De Oliveira Filho, Gevânio Bezerra, Ferreira, Jamile Magalhães, De Queiroz, Maria Goretti Rodrigues, Leite, Ana Cristina Lima, Pessoa, Cláudia
Published in Anais da Academia Brasileira de Ciências (01.03.2015)
Published in Anais da Academia Brasileira de Ciências (01.03.2015)
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Thiosemicarbazone and thiazole: in vitro evaluation of leishmanicidal and ultrastructural activity on Leishmania infantum
Queiroz, Camila Marques, de Oliveira Filho, Gevanio Bezerra, Espíndola, José Wanderlan Pontes, do Nascimento, Amanda Vasconcelos, Aliança, Amanda Silva dos Santos, de Lorena, Virginia Maria Barros, Feitosa, Ana Paula Sampaio, da Silva, Paula Roberta, Alves, Luiz Carlos, Leite, Ana Cristina Lima, Brayner, Fábio André
Published in Medicinal chemistry research (01.11.2020)
Published in Medicinal chemistry research (01.11.2020)
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Phthalimido-thiazole as privileged scaffold: activity against immature and adult worms of Schistosoma mansoni
de Oliveira, Sheilla Andrade, de Oliveira Barbosa, Miria, Filho, Carlos André Laranjeira Miranda, Oliveira, Arsênio Rodrigues, de Sousa, Fabiano Amaro, de Farias Santiago, Edna, de Oliveira Filho, Gevanio Bezerra, de Moraes Gomes, Paulo André Teixeira, da Conceição, Juliana Maria, Brayner, Fábio André, Alves, Luiz Carlos, Leite, Ana Cristina Lima
Published in Parasitology research (1987) (01.07.2018)
Published in Parasitology research (1987) (01.07.2018)
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A Novel High-Content Screening-Based Method for Anti-Trypanosoma cruzi Drug Discovery Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Portella, Diogo Crispim Nascimento, Rossi, Erik Aranha, Paredes, Bruno Diaz, Bastos, Tanira Matutino, Meira, Cássio Santana, Nonaka, Carolina Vasques Kymie, Silva, Daniela Nascimento, Improta-Caria, Alex, Moreira, Diogo Rodrigo Magalhaes, Leite, Ana Cristina Lima, de Oliveira Filho, Gevanio Bezerra, Filho, José Maria Barbosa, dos Santos, Ricardo Ribeiro, Soares, Milena Botelho Pereira, Souza, Bruno Solano de Freita
Published in Stem cells international (15.08.2021)
Published in Stem cells international (15.08.2021)
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Phthaloyl amino acids as anti-inflammatory and immunomodulatory prototypes
Leite, Ana Cristina Lima, Barbosa, Fábio Fernandes, Cardoso, Marcos Veríssimo de Oliveira, Moreira, Diogo R. M., Coêlho, Lucas Cunha D., da Silva, Elany Barbosa, Filho, Gevanio Bezerra de Oliveira, de Souza, Valdênia Maria Oliveira, Pereira, Valéria Rêgo A., de C. Reis, Luiza, Ferreira, Paulo Michel Pinheiro, Pessoa, Claudia, Wanderley, Almir Gonçalves, Mota, Fernanda Virgínia B., da Silva, Teresinha G.
Published in Medicinal chemistry research (01.04.2014)
Published in Medicinal chemistry research (01.04.2014)
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Novel phthalimide derivatives with TNF-α and IL-1β expression inhibitory and apoptotic inducing properties
Coêlho, Lucas Cunha Duarte, Cardoso, Marcos Veríssimo de Oliveira, Moreira, Diogo Rodrigo Magalhães, Gomes, Paulo André Teixeira de Moraes, Cavalcanti, Suellen Melo Tibúrcio, Oliveira, Arsenio Rodrigues, Filho, Gevanio Bezerra de Oliveira, Siqueira, Lucianna Rabelo Pessoa de, Barbosa, Miria de Oliveira, Borba, Elizabeth Fernanda de Oliveira, Silva, Teresinha Gonçalves da, Kaskow, Belinda, Karimi, Mahdad, Abraham, Lawrence J, Leite, Ana Cristina Lima
Published in MedChemComm (2014)
Published in MedChemComm (2014)
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Structural design, synthesis, and anti-Trypanosomatidae profile of new Pyridyl-thiazolidinones
Conceição, Juliana Maria da, Santos, Aline Caroline da Silva, Brayner, Fabio André, Alves, Luiz Carlos, Pinto, Aline Ferreira, Brondani, Graziella Leite, Oliveira Filho, Gevânio Bezerra de, Bedor, Danilo Cesar Galindo, Silva, José Wellithom Viturino da, Sales Junior, Policarpo Ademar, Cavalcante, Marton Kaique de Andrade, Silva, Elis Dionísio da, Pereira, Valéria Rêgo Alves, Leite, Ana Cristina Lima
Published in European journal of medicinal chemistry (05.06.2023)
Published in European journal of medicinal chemistry (05.06.2023)
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Evaluation of the Anti-Schistosoma mansoni Activity of Thiosemicarbazones and Thiazoles
SANTIAGO, Edna de Farias, ANDRADE DE OLIVEIRA, Sheilla, ARAUJO GONCALVES, Gabriel Gazzoni, BRAYNER, Fábio André, ALVES, Luiz Carlos, WANDERLEY, Almir Gonçalves, LIMA LEITE, Ana Cristina, DE OLIVEIRA, Gevânio Bezerra, MAGALHAES MOREIRA, Diogo Rodrigo, TEIXEIRA GOMES, Paulo André, DA SILVA, Anekécia Lauro, DE BARROS, Andréia Ferreira, DA SILVA, Aline Caroline, RAMOS DOS SANTOS, Thiago André, ALVES PEREIRA, Valéria Rêgo
Published in Antimicrobial Agents and Chemotherapy (01.01.2014)
Published in Antimicrobial Agents and Chemotherapy (01.01.2014)
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Improvement of in vivo anticancer and antiangiogenic potential of thalidomide derivatives
da Costa, Patrícia Marçal, da Costa, Marcilia Pinheiro, Carvalho, Adriana Andrade, Cavalcanti, Suellen Melo Tibúrcio, de Oliveira Cardoso, Marcos Veríssimo, de Oliveira Filho, Gevânio Bezerra, de Araújo Viana, Daniel, Fechine-Jamacaru, Francisco Vagnaldo, Leite, Ana Cristina Lima, de Moraes, Manoel Odorico, Pessoa, Claudia, Ferreira, Paulo Michel Pinheiro
Published in Chemico-biological interactions (05.09.2015)
Published in Chemico-biological interactions (05.09.2015)
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Structural design, synthesis and pharmacological evaluation of thiazoles against Trypanosoma cruzi
de Oliveira Filho, Gevanio Bezerra, Cardoso, Marcos Veríssimo de Oliveira, Espíndola, José Wanderlan Pontes, Oliveira e Silva, Dayane Albuquerque, Ferreira, Rafaela Salgado, Coelho, Pollyanne Lacerda, Anjos, Pâmela Silva dos, Santos, Emanuelle de Souza, Meira, Cássio Santana, Moreira, Diogo Rodrigo Magalhaes, Soares, Milena Botelho Pereira, Leite, Ana Cristina Lima
Published in European journal of medicinal chemistry (01.12.2017)
Published in European journal of medicinal chemistry (01.12.2017)
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Structural Investigation of Anti-Trypanosoma cruzi 2‑Iminothiazolidin-4-ones Allows the Identification of Agents with Efficacy in Infected Mice
Moreira, Diogo Rodrigo Magalhaes, Costa, Salvana Priscylla Manso, Hernandes, Marcelo Zaldini, Rabello, Marcelo Montenegro, de Oliveira Filho, Gevanio Bezerra, de Melo, Cristiane Moutinho Lagos, da Rocha, Lucas Ferreira, de Simone, Carlos Alberto, Ferreira, Rafaela Salgado, Fradico, Jordana Rodrigues Barbosa, Meira, Cássio Santana, Guimarães, Elisalva Teixeira, Srivastava, Rajendra Mohan, Pereira, Valéria Rêgo Alves, Soares, Milena Botelho Pereira, Leite, Ana Cristina Lima
Published in Journal of medicinal chemistry (27.12.2012)
Published in Journal of medicinal chemistry (27.12.2012)
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Compound profiling and 3D-QSAR studies of hydrazone derivatives with activity against intracellular Trypanosoma cruzi
Costa, Lívia Bandeira, Cardoso, Marcos Veríssimo de Oliveira, de Oliveira Filho, Gevanio Bezerra, de Moraes Gomes, Paulo André Teixeira, Espíndola, José Wanderlan Pontes, de Jesus Silva, Thays Gabrielle, Torres, Pedro Henrique Monteiro, Silva, Floriano Paes, Martin, Julio, de Figueiredo, Regina Célia Bressan Queiroz, Leite, Ana Cristina Lima
Published in Bioorganic & medicinal chemistry (15.04.2016)
Published in Bioorganic & medicinal chemistry (15.04.2016)
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Structural improvement of new thiazolidinones compounds with antinociceptive activity in experimental chemotherapy‐induced painful neuropathy
Moreira, Diogo Rodrigo Magalhaes, Santos, Dourivaldo Silva, Espírito Santo, Renan Fernandes do, Santos, Flávia Evangelista dos, Oliveira Filho, Gevanio Bezerra, Leite, Ana Cristina Lima, Soares, Milena Botelho Pereira, Villarreal, Cristiane Flora
Published in Chemical biology & drug design (01.08.2017)
Published in Chemical biology & drug design (01.08.2017)
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Synthesis, ADMET Prediction, and Antitumor Profile of Phenoxyhydrazine- 1,3-thiazoles Derivatives
de Siqueira, Lucianna Rabelo Pessoa, de Lima Ferreira, Larissa Pelágia, de Oliveira Filho, Gevanio Bezerra, de Oliveira, Marcos Victor Gregório, Pinto, Aline Ferreira, de Melo Silva, Vanessa Gouveia, de Moraes Gomes, Paulo André Teixeira, de Oliveira Cardoso, Marcos Veríssimo, de Nazaré Correia Soeiro, Maria, Dos Santos, Flaviana Alves, da Rocha Pitta, Maíra Galdino, Nunes, Janine Siqueira, de Melo Rego, Moacyr Jesus Barreto, Leite, Ana Cristina Lima
Published in Current topics in medicinal chemistry (2023)
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Published in Current topics in medicinal chemistry (2023)
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