Neoantigen-specific immunity in low mutation burden colorectal cancers of the consensus molecular subtype 4
van den Bulk, Jitske, Verdegaal, Els M E, Ruano, Dina, Ijsselsteijn, Marieke E, Visser, Marten, van der Breggen, Ruud, Duhen, Thomas, van der Ploeg, Manon, de Vries, Natasja L, Oosting, Jan, Peeters, Koen C M J, Weinberg, Andrew D, Farina-Sarasqueta, Arantza, van der Burg, Sjoerd H, de Miranda, Noel F C C
Published in Genome medicine (30.12.2019)
Published in Genome medicine (30.12.2019)
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PD-L1 blockade engages tumor-infiltrating lymphocytes to co-express targetable activating and inhibitory receptors
Beyrend, Guillaume, van der Gracht, Esmé, Yilmaz, Ayse, van Duikeren, Suzanne, Camps, Marcel, Höllt, Thomas, Vilanova, Anna, van Unen, Vincent, Koning, Frits, de Miranda, Noel F C C, Arens, Ramon, Ossendorp, Ferry
Published in Journal for immunotherapy of cancer (14.08.2019)
Published in Journal for immunotherapy of cancer (14.08.2019)
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Iron loading is a prominent feature of activated microglia in Alzheimer's disease patients
Kenkhuis, Boyd, Somarakis, Antonios, de Haan, Lorraine, Dzyubachyk, Oleh, IJsselsteijn, Marieke E, de Miranda, Noel F C C, Lelieveldt, Boudewijn P F, Dijkstra, Jouke, van Roon-Mom, Willeke M C, Höllt, Thomas, van der Weerd, Louise
Published in Acta neuropathologica communications (17.02.2021)
Published in Acta neuropathologica communications (17.02.2021)
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Immune subset-committed proliferating cells populate the human foetal intestine throughout the second trimester of gestation
Guo, Nannan, Li, Na, Jia, Li, Jiang, Qinyue, Schreurs, Mette, van Unen, Vincent, de Sousa Lopes, Susana M. Chuva, Vloemans, Alexandra A., Eggermont, Jeroen, Lelieveldt, Boudewijn, Staal, Frank J. T., de Miranda, Noel F. C. C., Pascutti, M. Fernanda, Koning, Frits
Published in Nature communications (10.03.2023)
Published in Nature communications (10.03.2023)
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Journal Article
Germline variant affecting p53β isoforms predisposes to familial cancer
Schubert, Stephanie A., Ruano, Dina, Joruiz, Sebastien M., Stroosma, Jordy, Glavak, Nikolina, Montali, Anna, Pinto, Lia M., Rodríguez-Girondo, Mar, Barge-Schaapveld, Daniela Q. C. M., Nielsen, Maartje, van Nesselrooij, Bernadette P. M., Mensenkamp, Arjen R., van Leerdam, Monique E., Sharp, Thomas H., Morreau, Hans, Bourdon, Jean-Christophe, de Miranda, Noel F. C. C., van Wezel, Tom
Published in Nature communications (18.09.2024)
Published in Nature communications (18.09.2024)
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The Variable Genomic Landscape During Osteosarcoma Progression: Insights From a Longitudinal WGS Analysis
Meijer, Debora M., Ruano, Dina, Briaire‐de Bruijn, Inge H., Wijers‐Koster, Pauline M., Sande, Michiel A. J., Gelderblom, Hans, Cleton‐Jansen, Anne‐Marie, Miranda, Noel F. C. C., Kuijjer, Marieke L., Bovée, Judith V. M. G.
Published in Genes chromosomes & cancer (01.07.2024)
Published in Genes chromosomes & cancer (01.07.2024)
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Journal Article
Mass Cytometric Analysis of Early-Stage Mycosis Fungoides
Guo, Nannan, Jia, Li, Out-Luiting, Coby, Miranda, Noel F C C de, Willemze, Rein, Koning, Frits, Vermeer, Maarten, Quint, Koen
Published in Cells (Basel, Switzerland) (22.03.2022)
Published in Cells (Basel, Switzerland) (22.03.2022)
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The C-type lectin DCIR contributes to the immune response and pathogenesis of colorectal cancer
Trimaglio, Giulia, Sneperger, Tamara, Raymond, Benjamin B. A., Gilles, Nelly, Näser, Emmanuelle, Locard-Paulet, Marie, Ijsselsteijn, Marieke E., Brouwer, Thomas P., Ecalard, Romain, Roelands, Jessica, Matsumoto, Naoki, Colom, André, Habch, Myriam, de Miranda, Noel F. C. C., Vergnolle, Nathalie, Devaud, Christel, Neyrolles, Olivier, Rombouts, Yoann
Published in Scientific reports (26.03.2024)
Published in Scientific reports (26.03.2024)
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Memory CD4+ T cells are generated in the human fetal intestine
Li, Na, van Unen, Vincent, Abdelaal, Tamim, Guo, Nannan, Kasatskaya, Sofya A., Ladell, Kristin, McLaren, James E., Egorov, Evgeny S., Izraelson, Mark, Chuva de Sousa Lopes, Susana M., Höllt, Thomas, Britanova, Olga V, Eggermont, Jeroen, de Miranda, Noel F. C. C., Chudakov, Dmitriy M., Price, David A., Lelieveldt, Boudewijn P. F., Koning, Frits
Published in Nature immunology (01.03.2019)
Published in Nature immunology (01.03.2019)
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Integration of mass cytometry and mass spectrometry imaging for spatially resolved single-cell metabolic profiling
Nunes, Joana B., Ijsselsteijn, Marieke E., Abdelaal, Tamim, Ursem, Rick, van der Ploeg, Manon, Giera, Martin, Everts, Bart, Mahfouz, Ahmed, Heijs, Bram, de Miranda, Noel F. C. C.
Published in Nature methods (01.10.2024)
Published in Nature methods (01.10.2024)
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Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell cycle progression in a preclinical model
Kumar, Sumit, Schoonderwoerd, Mark J A, Kroonen, Jessie S, de Graaf, Ilona J, Sluijter, Marjolein, Ruano, Dina, González-Prieto, Román, Verlaan-de Vries, Matty, Rip, Jasper, Arens, Ramon, de Miranda, Noel F C C, Hawinkels, Lukas J A C, van Hall, Thorbald, Vertegaal, Alfred C O
Published in Gut (01.11.2022)
Published in Gut (01.11.2022)
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High-dimensional cytometric analysis of colorectal cancer reveals novel mediators of antitumour immunity
de Vries, Natasja L, van Unen, Vincent, Ijsselsteijn, Marieke E, Abdelaal, Tamim, van der Breggen, Ruud, Farina Sarasqueta, Arantza, Mahfouz, Ahmed, Peeters, Koen C M J, Höllt, Thomas, Lelieveldt, Boudewijn P F, Koning, Frits, de Miranda, Noel F C C
Published in Gut (01.04.2020)
Published in Gut (01.04.2020)
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Transcriptomic and immunophenotypic profiling reveals molecular and immunological hallmarks of colorectal cancer tumourigenesis
Roelands, Jessica, van der Ploeg, Manon, Ijsselsteijn, Marieke E, Dang, Hao, Boonstra, Jurjen J, Hardwick, James C H, Hawinkels, Lukas J A C, Morreau, Hans, de Miranda, Noel F C C
Published in Gut (01.07.2023)
Published in Gut (01.07.2023)
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Journal Article
A 40-Marker Panel for High Dimensional Characterization of Cancer Immune Microenvironments by Imaging Mass Cytometry
Ijsselsteijn, Marieke E, van der Breggen, Ruud, Farina Sarasqueta, Arantza, Koning, Frits, de Miranda, Noel F C C
Published in Frontiers in immunology (29.10.2019)
Published in Frontiers in immunology (29.10.2019)
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Neoadjuvant atezolizumab plus chemotherapy in gastric and gastroesophageal junction adenocarcinoma: the phase 2 PANDA trial
Verschoor, Yara L., van de Haar, Joris, van den Berg, José G., van Sandick, Johanna W., Kodach, Liudmila L., van Dieren, Jolanda M., Balduzzi, Sara, Grootscholten, Cecile, IJsselsteijn, Marieke E., Veenhof, Alexander A. F. A., Hartemink, Koen J., Vollebergh, Marieke A., Jurdi, Adham, Sharma, Shruti, Spickard, Erik, Owers, Emilia C., Bartels-Rutten, Annemarieke, den Hartog, Peggy, de Miranda, Noel F. C. C., van Leerdam, Monique E., Haanen, John B. A. G., Schumacher, Ton N., Voest, Emile E., Chalabi, Myriam
Published in Nature medicine (01.02.2024)
Published in Nature medicine (01.02.2024)
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Germline NPAT inactivating variants as cause of hereditary colorectal cancer
Terradas, Mariona, Schubert, Stephanie A, Viana-Errasti, Julen, Ruano, Dina, Aiza, Gemma, Nielsen, Maartje, Marciel, Paula, Tops, Carli M, Parra, Genís, Morreau, Hans, Torrents, David, van Leerdam, Monique E, Capellá, Gabriel, de Miranda, Noel F C C, Valle, Laura, van Wezel, Tom
Published in European journal of human genetics : EJHG (01.07.2024)
Published in European journal of human genetics : EJHG (01.07.2024)
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Author Correction: Neoadjuvant atezolizumab plus chemotherapy in gastric and gastroesophageal junction adenocarcinoma: the phase 2 PANDA trial
Verschoor, Yara L., van de Haar, Joris, van den Berg, José G., van Sandick, Johanna W., Kodach, Liudmila L., van Dieren, Jolanda M., Balduzzi, Sara, Grootscholten, Cecile, IJsselsteijn, Marieke E., Veenhof, Alexander A. F. A., Hartemink, Koen J., Vollebergh, Marieke A., Jurdi, Adham, Sharma, Shruti, Spickard, Erik, Owers, Emilia C., Bartels-Rutten, Annemarieke, den Hartog, Peggy, de Miranda, Noel F. C. C., van Leerdam, Monique E., Haanen, John B. A. G., Schumacher, Ton N., Voest, Emile E., Chalabi, Myriam
Published in Nature medicine (01.05.2024)
Published in Nature medicine (01.05.2024)
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Journal Article
Linking Immunity with Genomics in Sarcomas: Is Genomic Complexity an Immunogenic Trigger?
van Oost, Siddh, Meijer, Debora M, Kuijjer, Marieke L, Bovée, Judith V M G, de Miranda, Noel F C C
Published in Biomedicines (19.08.2021)
Published in Biomedicines (19.08.2021)
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