Characterization of Clinical Absorption, Distribution, Metabolism, and Excretion and Pharmacokinetics of Velsecorat Using an Intravenous Microtracer Combined with an Inhaled Dose in Healthy Subjects
Holmberg, Ann Aurell, Weidolf, Lars, Necander, Sofia, Bold, Peter, Sidhu, Sharan, Pelay-Gimeno, Marta, de Ligt, Rianne A F, Verheij, Elwin R, Jauhiainen, Alexandra, Psallidas, Ioannis, Wählby Hamrén, Ulrika, Prothon, Susanne
Published in Drug metabolism and disposition (01.02.2022)
Published in Drug metabolism and disposition (01.02.2022)
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Application of Accelerator Mass Spectrometry to Characterize the Mass Balance Recovery and Disposition of AZD4831, a Novel Myeloperoxidase Inhibitor, following Administration of an Oral Radiolabeled Microtracer Dose in Humans
Bhattacharya, Chandrali, Sandinge, Ann-Sofie, Bragg, Ryan A, Heijer, Maria, Yan, Jingjing, Andersson, Linda C, Jurva, Ulrik, Pelay-Gimeno, Marta, Vaes, Wouter H J, de Ligt, Rianne A F, Gränfors, Malin, Amilon, Carl, Lindstedt, Eva-Lotte, Menakuru, Somasekhara R, Garkaviy, Pavlo, Weidolf, Lars, Gopaul, V Sashi
Published in Drug metabolism and disposition (01.04.2023)
Published in Drug metabolism and disposition (01.04.2023)
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Journal Article
Inverse agonism at adenosine A1 receptors
de Ligt, Rianne A.F, Lorenzen, Anna, IJzerman, Adriaan P
Published in International Congress series (01.08.2003)
Published in International Congress series (01.08.2003)
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Journal Article
Subjective feelings of appetite of wholegrain breakfasts evaluated under controlled, laboratory and ‘at home’ conditions
Pasman, Wilrike J., Hendriks, Henk F.J., Minekus, Mans M., de Ligt, Rianne A.F., Scholtes-Timmerman, Maarten J., Clabbers, Nard D.S., Leonards, Nynke M., Johnson, Jodee, Bellmann, Susann
Published in Physiology & behavior (01.10.2018)
Published in Physiology & behavior (01.10.2018)
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Journal Article
A locked-on, constitutively active mutant of the adenosine A1 receptor
DE LIGT, Rianne A. F, RIVKEES, Scott A, LORENZEN, Anna, LEURS, Rob, IJZERMAN, Ad P
Published in European journal of pharmacology (07.03.2005)
Published in European journal of pharmacology (07.03.2005)
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Journal Article
Allosteric modulation and constitutive activity of fusion proteins between the adenosine A 1 receptor and different 351Cys-mutated G i α-subunits
Klaasse, Elisabeth, de Ligt, Rianne A.F., Roerink, Sophie F., Lorenzen, Anna, Milligan, Graeme, Leurs, Rob, IJzerman, Ad P.
Published in European journal of pharmacology (2004)
Published in European journal of pharmacology (2004)
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Journal Article
Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi α-subunits
KLAASSE, Elisabeth, DE LIGT, Rianne A. F, ROERINK, Sophie F, LORENZEN, Anna, MILLIGAN, Graeme, LEURS, Rob, IJZERMAN, Ad P
Published in European journal of pharmacology (19.09.2004)
Published in European journal of pharmacology (19.09.2004)
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Journal Article
The influence of microbial metabolites on human intestinal epithelial cells and macrophages in vitro
van Nuenen, Marleen H.M.C., de Ligt, Rianne A.F., Doornbos, Robert P., van der Woude, Janneke C.J., Kuipers, Ernst J., Venema, Koen
Published in FEMS immunology and medical microbiology (01.08.2005)
Published in FEMS immunology and medical microbiology (01.08.2005)
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Journal Article
Synthesis and biological evaluation of disubstituted N6-cyclopentyladenine analogues
de Ligt, Rianne A.F., van der Klein, Pieter A.M., von Frijtag Drabbe Künzel, Jacobien K., Lorenzen, Anna, Ait El Maate, Fatna, Fujikawa, Shelly, van Westhoven, Rosemarijn, van den Hoven, Thijs, Brussee, Johannes, IJzerman, Ad P.
Published in Bioorganic & medicinal chemistry (01.01.2004)
Published in Bioorganic & medicinal chemistry (01.01.2004)
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Journal Article
Synthesis and biological evaluation of disubstituted N6-cyclopentyladenine analogues: the search for a neutral antagonist with high affinity for the adenosine A1 receptor
de Ligt, Rianne A.F., van der Klein, Pieter A.M., von Frijtag Drabbe Künzel, Jacobien K., Lorenzen, Anna, Ait El Maate, Fatna, Fujikawa, Shelly, van Westhoven, Rosemarijn, van den Hoven, Thijs, Brussee, Johannes, IJzerman, Ad P.
Published in Bioorganic & medicinal chemistry (02.01.2004)
Published in Bioorganic & medicinal chemistry (02.01.2004)
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Journal Article
Inverse agonism at adenosine A 1 receptors
de Ligt, Rianne A.F, Lorenzen, Anna, IJzerman, Adriaan P
Published in International Congress series (2003)
Published in International Congress series (2003)
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Journal Article