Drug susceptibility of Mycobacterium tuberculosis Beijing genotype and association with MDR TB
de Steenwinkel, Jurriaan E M, ten Kate, Marian T, de Knegt, Gerjo J, Kremer, Kristin, Aarnoutse, Rob E, Boeree, Martin J, Verbrugh, Henri A, van Soolingen, Dick, Bakker-Woudenberg, Irma A J M
Published in Emerging infectious diseases (01.04.2012)
Published in Emerging infectious diseases (01.04.2012)
Get full text
Journal Article
Distinctive cytokines as biomarkers predicting fatal outcome of severe Staphylococcus aureus bacteremia in mice
van den Berg, Sanne, Laman, Jon D, Boon, Louis, ten Kate, Marian T, de Knegt, Gerjo J, Verdijk, Rob M, Verbrugh, Henri A, Nouwen, Jan L, Bakker-Woudenberg, Irma A J M
Published in PloS one (08.03.2013)
Published in PloS one (08.03.2013)
Get full text
Journal Article
Consequences of Noncompliance for Therapy Efficacy and Emergence of Resistance in Murine Tuberculosis Caused by the Beijing Genotype of Mycobacterium tuberculosis
DE STEENWINKEL, Jurriaan E. M, TEN KATE, Marian T, DE KNEGT, Gerjo J, VERBRUGH, Henri A, AARNOUTSE, Rob E, BOEREE, Martin J, DEN BAKKER, Michael A, VAN SOOLINGEN, Dick, BAKKER-WOUDENBERG, Irma A. J. M
Published in Antimicrobial Agents and Chemotherapy (01.09.2012)
Published in Antimicrobial Agents and Chemotherapy (01.09.2012)
Get full text
Journal Article
The Role of Efflux Pumps in Tuberculosis Treatment and Their Promise as a Target in Drug Development: Unraveling the Black Box
te Brake, Lindsey H.M, de Knegt, Gerjo J, de Steenwinkel, Jurriaan E, van Dam, Teunis J.P, Burger, David M, Russel, Frans G.M, van Crevel, Reinout, Koenderink, Jan B, Aarnoutse, Rob E
Published in Annual review of pharmacology and toxicology (06.01.2018)
Published in Annual review of pharmacology and toxicology (06.01.2018)
Get full text
Journal Article
Mycobacterium tuberculosis clinical isolates of the Beijing and East-African Indian lineage induce fundamentally different host responses in mice compared to H37Rv
Mourik, Bas C, de Steenwinkel, Jurriaan E M, de Knegt, Gerjo J, Huizinga, Ruth, Verbon, Annelies, Ottenhoff, Tom H M, van Soolingen, Dick, Leenen, Pieter J M
Published in Scientific reports (27.12.2019)
Published in Scientific reports (27.12.2019)
Get full text
Journal Article
Optimization of the Rifampin Dosage to Improve the Therapeutic Efficacy in Tuberculosis Treatment Using a Murine Model
DE STEENWINKEL, Jurriaan E. M, AARNOUTSE, Rob E, DE KNEGT, Gerjo J, TEN KATE, Marian T, TEULEN, Marga, VERBRUGH, Henri A, BOEREE, Martin J, SOOLINGEN, Dick Van, BAKKER-WOUDENBERG, Irma A. J. M
Published in American journal of respiratory and critical care medicine (15.05.2013)
Published in American journal of respiratory and critical care medicine (15.05.2013)
Get full text
Journal Article
Assessment of the Additional Value of Verapamil to a Moxifloxacin and Linezolid Combination Regimen in a Murine Tuberculosis Model
Pieterman, Elise D, Te Brake, Lindsey H M, de Knegt, Gerjo J, van der Meijden, Aart, Alffenaar, Jan-Willem C, Bax, Hannelore I, Aarnoutse, Rob E, de Steenwinkel, Jurriaan E M
Published in Antimicrobial agents and chemotherapy (01.09.2018)
Published in Antimicrobial agents and chemotherapy (01.09.2018)
Get full text
Journal Article
Assessment of Bactericidal Drug Activity and Treatment Outcome in a Mouse Tuberculosis Model Using a Clinical Beijing Strain
Mourik, Bas C, de Knegt, Gerjo J, Verbon, Annelies, Mouton, Johan W, Bax, Hannelore I, de Steenwinkel, Jurriaan E M
Published in Antimicrobial agents and chemotherapy (01.10.2017)
Published in Antimicrobial agents and chemotherapy (01.10.2017)
Get full text
Journal Article
Immunotherapy Added to Antibiotic Treatment Reduces Relapse of Disease in a Mouse Model of Tuberculosis
Mourik, Bas C, Leenen, Pieter J M, de Knegt, Gerjo J, Huizinga, Ruth, van der Eerden, Bram C J, Wang, Jinshan, Krois, Charles R, Napoli, Joseph L, Bakker-Woudenberg, Irma A J M, de Steenwinkel, Jurriaan E M
Published in American journal of respiratory cell and molecular biology (01.02.2017)
Published in American journal of respiratory cell and molecular biology (01.02.2017)
Get full text
Journal Article
Activity of moxifloxacin and linezolid against Mycobacterium tuberculosis in combination with potentiator drugs verapamil, timcodar, colistin and SQ109
de Knegt, Gerjo J, van der Meijden, Aart, de Vogel, Corné P, Aarnoutse, Rob E, de Steenwinkel, Jurriaan E.M
Published in International journal of antimicrobial agents (01.03.2017)
Published in International journal of antimicrobial agents (01.03.2017)
Get full text
Journal Article
Inhibitory potential of tuberculosis drugs on ATP-binding cassette drug transporters
te Brake, Lindsey H.M, Russel, Frans G.M, van den Heuvel, Jeroen J.M.W, de Knegt, Gerjo J, de Steenwinkel, Jurriaan E, Burger, David M, Aarnoutse, Rob E, Koenderink, Jan B
Published in Tuberculosis (Edinburgh, Scotland) (01.01.2016)
Published in Tuberculosis (Edinburgh, Scotland) (01.01.2016)
Get full text
Journal Article
Assessment of treatment response by colony forming units, time to culture positivity and the molecular bacterial load assay compared in a mouse tuberculosis model
de Knegt, Gerjo J, Dickinson, Laura, Pertinez, Henry, Evangelopoulos, Dimitrios, McHugh, Timothy D, Bakker-Woudenberg, Irma A.J.M, Davies, Gerry R, de Steenwinkel, Jurriaan E.M
Published in Tuberculosis (Edinburgh, Scotland) (01.07.2017)
Published in Tuberculosis (Edinburgh, Scotland) (01.07.2017)
Get full text
Journal Article
Assessing Pharmacodynamic Interactions in Mice Using the Multistate Tuberculosis Pharmacometric and General Pharmacodynamic Interaction Models
Chen, Chunli, Wicha, Sebastian G., de Knegt, Gerjo J., Ortega, Fatima, Alameda, Laura, Sousa, Veronica, de Steenwinkel, Jurriaan E. M., Simonsson, Ulrika S. H.
Published in CPT: pharmacometrics and systems pharmacology (01.11.2017)
Published in CPT: pharmacometrics and systems pharmacology (01.11.2017)
Get full text
Journal Article
Rifampicin-induced transcriptome response in rifampicin-resistant Mycobacterium tuberculosis
de Knegt, Gerjo J, Bruning, Oskar, ten Kate, Marian T, de Jong, Mark, van Belkum, Alex, Endtz, Hubert P, Breit, Timo M, Bakker-Woudenberg, Irma A.J.M, de Steenwinkel, Jurriaan E.M
Published in Tuberculosis (Edinburgh, Scotland) (01.01.2013)
Published in Tuberculosis (Edinburgh, Scotland) (01.01.2013)
Get full text
Journal Article
SILA-421 activity in vitro against rifampicin-susceptible and rifampicin-resistant Mycobacterium tuberculosis , and in vivo in a murine tuberculosis model
de Knegt, Gerjo J, Bakker-Woudenberg, Irma A.J.M, van Soolingen, Dick, Aarnoutse, Rob, Boeree, Martin J, de Steenwinkel, Jurriaan E.M
Published in International journal of antimicrobial agents (01.07.2015)
Published in International journal of antimicrobial agents (01.07.2015)
Get full text
Journal Article
Enhancement of in vitro activity of tuberculosis drugs by addition of thioridazine is not reflected by improved in vivo therapeutic efficacy
de Knegt, Gerjo J, ten Kate, Marian T, van Soolingen, Dick, Aarnoutse, Rob, Boeree, Martin J, Bakker-Woudenberg, Irma A.J.M, de Steenwinkel, Jurriaan E.M
Published in Tuberculosis (Edinburgh, Scotland) (01.12.2014)
Published in Tuberculosis (Edinburgh, Scotland) (01.12.2014)
Get full text
Journal Article
Time–kill kinetics of anti-tuberculosis drugs, and emergence of resistance, in relation to metabolic activity of Mycobacterium tuberculosis
de Steenwinkel, Jurriaan E. M., de Knegt, Gerjo J., ten Kate, Marian T., van Belkum, Alex, Verbrugh, Henri A., Kremer, Kristin, van Soolingen, Dick, Bakker-Woudenberg, Irma A. J. M.
Published in Journal of antimicrobial chemotherapy (01.12.2010)
Published in Journal of antimicrobial chemotherapy (01.12.2010)
Get full text
Journal Article
Relapse of tuberculosis versus primary tuberculosis; course, pathogenesis and therapy in mice
de Steenwinkel, Jurriaan E.M, de Knegt, Gerjo J, ten Kate, Marian T, Verbrugh, Henri A, Hernandez-Pando, R, Leenen, Pieter J.M, Bakker-Woudenberg, Irma A.J.M
Published in Tuberculosis (Edinburgh, Scotland) (01.03.2013)
Published in Tuberculosis (Edinburgh, Scotland) (01.03.2013)
Get full text
Journal Article
Enhancement of in vitro activity of tuberculosis drugs by addition of thioridazine is not reflected by improved in vivo therapeutic efficacy
de Knegt, Gerjo J, ten Kate, Marian T, van Soolingen, Dick, Aarnoutse, Rob, Boeree, Martin J, Bakker-Woudenberg, Irma A J M, de Steenwinkel, Jurriaan E M
Published in Tuberculosis (Edinburgh, Scotland) (01.12.2014)
Get full text
Published in Tuberculosis (Edinburgh, Scotland) (01.12.2014)
Journal Article