Evaluation of simulated driving in comparison to laboratory-based tests to assess the pharmacodynamics of alprazolam and alcohol
Huizinga, Coen Rh, Zuiker, Rob G, de Kam, Marieke L, Ziagkos, Dimitrios, Kuipers, Jorrit, Mejia, Yuri, van Gerven, Joop Ma, Cohen, Adam F
Published in Journal of psychopharmacology (Oxford) (01.07.2019)
Published in Journal of psychopharmacology (Oxford) (01.07.2019)
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Immune Monitoring of Mycophenolate Mofetil Activity in Healthy Volunteers Using Ex Vivo T Cell Function Assays
In 't Veld, Aliede E, Jansen, Manon A A, de Kam, Marieke L, Yavuz, Yalҫin, Moes, Dirk Jan A R, Oudhoff, Kathalijne A, van Poelgeest, Mariette I E, Burggraaf, Jacobus, Moerland, Matthijs
Published in Pharmaceutics (31.05.2023)
Published in Pharmaceutics (31.05.2023)
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Detection of colorectal polyps in humans using an intravenously administered fluorescent peptide targeted against c-Met
Burggraaf, Jacobus, Kamerling, Ingrid M C, Gordon, Paul B, Schrier, Lenneke, de Kam, Marieke L, Kales, Andrea J, Bendiksen, Ragnar, Indrevoll, Bård, Bjerke, Roger M, Moestue, Siver A, Yazdanfar, Siavash, Langers, Alexandra M J, Swaerd-Nordmo, Marit, Torheim, Geir, Warren, Madhuri V, Morreau, Hans, Voorneveld, Philip W, Buckle, Tessa, van Leeuwen, Fijs W B, Ødegårdstuen, Liv-Ingrid, Dalsgaard, Grethe T, Healey, Andrew, Hardwick, James C H
Published in Nature medicine (01.08.2015)
Published in Nature medicine (01.08.2015)
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Journal Article
Inflammatory plasma biomarkers in subjects with preclinical Alzheimer's disease
Prins, Samantha, de Kam, Marieke L, Teunissen, Charlotte E, Groeneveld, Geert Jan
Published in Alzheimer's research & therapy (03.08.2022)
Published in Alzheimer's research & therapy (03.08.2022)
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A randomized single and multiple ascending dose study in healthy volunteers of LTI‐291, a centrally penetrant glucocerebrosidase activator
Heijer, Jonas M., Kruithof, Annelieke C., Amerongen, Guido, Kam, Marieke L., Thijssen, Eva, Grievink, Hendrika W., Moerland, Matthijs, Walker, Mike, Been, Kees, Skerlj, Renato, Justman, Craig, Dudgeon, Lindsay, Lansbury, Peter, Cullen, Valerie C., Hilt, Dana C., Groeneveld, Geert Jan
Published in British journal of clinical pharmacology (01.09.2021)
Published in British journal of clinical pharmacology (01.09.2021)
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Journal Article
A multimodal, comprehensive characterization of a cutaneous wound model in healthy volunteers
ten Voorde, Wouter, Saghari, Mahdi, Boltjes, Jiry, de Kam, Marieke L., Zhuparris, Ahnjili, Feiss, Gary, Buters, Thomas P., Prens, Errol P., Damman, Jeffrey, Niemeyer‐van der Kolk, Tessa, Moerland, Matthijs, Burggraaf, Jacobus, van Doorn, Martijn B. A., Rissmann, Robert
Published in Experimental dermatology (01.07.2023)
Published in Experimental dermatology (01.07.2023)
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Finding Suitable Clinical Endpoints for a Potential Treatment of a Rare Genetic Disease: the Case of ARID1B
Kruizinga, Matthijs D., Zuiker, Rob G.J.A., Sali, Elif, de Kam, Marieke L., Doll, Robert J., Groeneveld, Geert Jan, Santen, Gijs W.E., Cohen, Adam F.
Published in Neurotherapeutics (01.07.2020)
Published in Neurotherapeutics (01.07.2020)
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Treatment with the Topical Antimicrobial Peptide Omiganan in Mild-to-Moderate Facial Seborrheic Dermatitis versus Ketoconazole and Placebo: Results of a Randomized Controlled Proof-of-Concept Trial
Rousel, Jannik, Saghari, Mahdi, Pagan, Lisa, Nădăban, Andreea, Gambrah, Tom, Theelen, Bart, de Kam, Marieke L, Haakman, Jorine, van der Wall, Hein E C, Feiss, Gary L, Niemeyer-van der Kolk, Tessa, Burggraaf, Jacobus, Bouwstra, Joke A, Rissmann, Robert, van Doorn, Martijn B A
Published in International journal of molecular sciences (01.09.2023)
Published in International journal of molecular sciences (01.09.2023)
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Journal Article
Peripheral selectivity of the novel cannabinoid receptor antagonist TM38837 in healthy subjects
Klumpers, Linda E., Fridberg, Marianne, Kam, Marieke L., Little, Paul B., Jensen, Niels Ole, Kleinloog, Hendrik D., Elling, Christian E., Gerven, Joop M. A.
Published in British journal of clinical pharmacology (01.12.2013)
Published in British journal of clinical pharmacology (01.12.2013)
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A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Evaluate the Pharmacodynamic Effects of VX-150, a Highly Selective NaV1.8 Inhibitor, in Healthy Male Adults
Hijma, Hemme J, Siebenga, Pieter S, de Kam, Marieke L, Groeneveld, Geert Jan
Published in Pain medicine (Malden, Mass.) (06.08.2021)
Published in Pain medicine (Malden, Mass.) (06.08.2021)
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Oral prednisolone suppresses skin inflammation in a healthy volunteer imiquimod challenge model
Assil, Salma, Buters, Thomas P, Hameeteman, Pieter W, Hallard, Charlie, Treijtel, Nicoline, Niemeyer-Van der Kolk, Tessa, de Kam, Marieke L, Florencia, Edwin F I I I, Prens, Errol P, van Doorn, Martijn B A, Rissmann, Robert, Klarenbeek, Naomi B, Jansen, Manon A A, Moerland, Matthijs
Published in Frontiers in immunology (20.07.2023)
Published in Frontiers in immunology (20.07.2023)
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Efficacy and safety of RPL554, a dual PDE3 and PDE4 inhibitor, in healthy volunteers and in patients with asthma or chronic obstructive pulmonary disease: findings from four clinical trials
Franciosi, Lui G, Diamant, Zuzana, Banner, Katharine H, Zuiker, Rob, Morelli, Nicoletta, Kamerling, Ingrid M C, de Kam, Marieke L, Burggraaf, Jacobus, Cohen, Adam F, Cazzola, Mario, Calzetta, Luigino, Singh, Dave, Spina, Domenico, Walker, Michael J A, Page, Clive P
Published in The lancet respiratory medicine (01.11.2013)
Published in The lancet respiratory medicine (01.11.2013)
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Immunomonitoring of Tacrolimus in Healthy Volunteers: The First Step from PK- to PD-Based Therapeutic Drug Monitoring?
In 't Veld, Aliede E, Grievink, Hendrika W, Saghari, Mahdi, Stuurman, Frederik E, de Kam, Marieke L, de Vries, Aiko P J, de Winter, Brenda C M, Burggraaf, Jacobus, Cohen, Adam F, Moerland, Matthijs
Published in International journal of molecular sciences (23.09.2019)
Published in International journal of molecular sciences (23.09.2019)
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Monitoring of Ex Vivo Cyclosporin a Activity in Healthy Volunteers Using T Cell Function Assays in Relation to Whole Blood and Cellular Pharmacokinetics
in ’t Veld, Aliede E., Jansen, Manon A. A., Huisman, Bertine W., Schoonakker, Mascha, de Kam, Marieke L., Moes, Dirk Jan A. R., van Poelgeest, Mariëtte I. E., Burggraaf, Jacobus, Moerland, Matthijs
Published in Pharmaceutics (01.09.2022)
Published in Pharmaceutics (01.09.2022)
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Effects of morphine and alcohol on functional brain connectivity during "resting state":A placebo-controlled crossover study in healthy young men
Khalili-Mahani, Najmeh, Zoethout, Remco M.W., Beckmann, Christian F., Baerends, Evelinda, de Kam, Marieke L., Soeter, Roelof P., Dahan, Albert, van Buchem, Mark A., van Gerven, Joop M.A., Rombouts, Serge A.R.B.
Published in Human brain mapping (01.05.2012)
Published in Human brain mapping (01.05.2012)
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Journal Article
Cognitive performance in healthy clinical trial participants and patients with the NeuroCart, a neurodegenerative disease measured with an automated neuropsychological and neurophysiological test battery
Prins, Samantha, Borghans, Laura, de Kam, Marieke L., Groeneveld, Geert Jan, van Gerven, Joop
Published in Journal of the neurological sciences (15.06.2023)
Published in Journal of the neurological sciences (15.06.2023)
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Journal Article
Characterization of the Pharmacokinetic and Pharmacodynamic Profile of Apraglutide, a Glucagon-Like Peptide-2 Analog, in Healthy Volunteers
Bolognani, Federico, Kruithof, Annelieke C, Schulthess, Pascal, Machacek, Matthias, de Kam, Marieke L, Bergmann, Kirsten R, van Gent, Max, Moerland, Matthijs, Crenn, Pascal, Greig, Gérard, Gal, Pim
Published in The Journal of pharmacology and experimental therapeutics (01.08.2023)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2023)
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Vaccination during myeloid cell depletion by cancer chemotherapy fosters robust T cell responses
Welters, Marij J, van der Sluis, Tetje C, van Meir, Hélène, Loof, Nikki M, van Ham, Vanessa J, van Duikeren, Suzanne, Santegoets, Saskia J, Arens, Ramon, de Kam, Marieke L, Cohen, Adam F, van Poelgeest, Mariette I, Kenter, Gemma G, Kroep, Judith R, Burggraaf, Jacobus, Melief, Cornelis J, van der Burg, Sjoerd H
Published in Science translational medicine (13.04.2016)
Published in Science translational medicine (13.04.2016)
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Cannabidiol Increases Psychotropic Effects and Plasma Concentrations of Δ 9 -Tetrahydrocannabinol Without Improving Its Analgesic Properties
Gorbenko, Andriy A, Heuberger, Jules A A C, Klumpers, Linda E, de Kam, Marieke L, Strugala, Pamela K, de Visser, Saco J, Groeneveld, Geert J
Published in Clinical pharmacology and therapeutics (01.11.2024)
Published in Clinical pharmacology and therapeutics (01.11.2024)
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Cannabidiol Increases Psychotropic Effects and Plasma Concentrations of Δ9‐Tetrahydrocannabinol Without Improving Its Analgesic Properties
Gorbenko, Andriy A., Heuberger, Jules A.A.C., Klumpers, Linda E., Kam, Marieke L., Strugala, Pamela K., Visser, Saco J., Groeneveld, Geert J.
Published in Clinical pharmacology and therapeutics (01.11.2024)
Published in Clinical pharmacology and therapeutics (01.11.2024)
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