Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32
Esparza-Gordillo, Jorge, Jorge, Elena Goicoechea de, Buil, Alfonso, Berges, Luis Carreras, López-Trascasa, Margarita, Sánchez-Corral, Pilar, Córdoba, Santiago Rodríguez de
Published in Human molecular genetics (01.03.2005)
Published in Human molecular genetics (01.03.2005)
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Journal Article
Dimerization of complement factor H-related proteins modulates complement activation in vivo
de Jorge, Elena Goicoechea, Caesar, Joseph J. E., Malik, Talat H., Patel, Mitali, Colledge, Matthew, Johnson, Steven, Hakobyan, Svetlana, Morgan, B. Paul, Harris, Claire L., Pickering, Matthew C., Lea, Susan M.
Published in Proceedings of the National Academy of Sciences - PNAS (19.03.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (19.03.2013)
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Journal Article
Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome
Goicoechea de Jorge, Elena, Harris, Claire L, Esparza-Gordillo, Jorge, Carreras, Luis, Aller Arranz, Elena, Abarrategui Garrido, Cynthia, López-Trascasa, Margarita, Sánchez-Corral, Pilar, Morgan, B. Paul, Rodríguez de Córdoba, Santiago
Published in Proceedings of the National Academy of Sciences - PNAS (02.01.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (02.01.2007)
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Journal Article
Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains
Pickering, Matthew C, de Jorge, Elena Goicoechea, Martinez-Barricarte, Rubén, Recalde, Sergio, Garcia-Layana, Alfredo, Rose, Kirsten L, Moss, Jill, Walport, Mark J, Cook, H Terence, de Córdoba, Santiago Rodriguez, Botto, Marina
Published in The Journal of experimental medicine (11.06.2007)
Published in The Journal of experimental medicine (11.06.2007)
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Journal Article
Acute Presentation and Persistent Glomerulonephritis Following Streptococcal Infection in a Patient With Heterozygous Complement Factor H–Related Protein 5 Deficiency
Vernon, Katherine A., MB, BS, Goicoechea de Jorge, Elena, PhD, Hall, Angela E., FIBMS, Fremeaux-Bacchi, Veronique, PhD, Aitman, Timothy J., FMedSci, Cook, H. Terence, FMedSci, Hangartner, Robert, FRCPath, Koziell, Ania, PhD, Pickering, Matthew C., PhD
Published in American journal of kidney diseases (01.07.2012)
Published in American journal of kidney diseases (01.07.2012)
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Journal Article
Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis
Gale, Daniel P, MRCP, de Jorge, Elena Goicoechea, PhD, Cook, H Terence, Prof, Martinez-Barricarte, Rubén, PhD, Hadjisavvas, Andreas, PhD, McLean, Adam G, FRCP, Pusey, Charles D, Prof, Pierides, Alkis, FRCP, Kyriacou, Kyriacos, PhD, Athanasiou, Yiannis, MD, Voskarides, Konstantinos, PhD, Deltas, Constantinos, Prof, Palmer, Andrew, FRCP, Frémeaux-Bacchi, Véronique, PhD, de Cordoba, Santiago Rodriguez, Prof, Maxwell, Patrick H, Prof, Pickering, Matthew C, Prof
Published in The Lancet (British edition) (04.09.2010)
Published in The Lancet (British edition) (04.09.2010)
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Journal Article
The interactive Factor H-atypical hemolytic uremic syndrome mutation database and website: update and integration of membrane cofactor protein and Factor I mutations with structural models
Saunders, Rebecca E., Abarrategui-Garrido, Cynthia, Frémeaux-Bacchi, Véronique, Goicoechea de Jorge, Elena, Goodship, Timothy H.J., López Trascasa, Margarita, Noris, Marina, Ponce Castro, Isabel Maria, Remuzzi, Giuseppe, Rodríguez de Córdoba, Santiago, Sánchez-Corral, Pilar, Skerka, Christine, Zipfel, Peter F., Perkins, Stephen J.
Published in Human mutation (01.03.2007)
Published in Human mutation (01.03.2007)
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Journal Article
Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules
Johnson, Steven, Tan, Lionel, van der Veen, Stijn, Caesar, Joseph, Goicoechea De Jorge, Elena, Harding, Rachel J, Bai, Xilian, Exley, Rachel M, Ward, Philip N, Ruivo, Nicola, Trivedi, Kaushali, Cumber, Elspeth, Jones, Rhian, Newham, Luke, Staunton, David, Ufret-Vincenty, Rafael, Borrow, Ray, Pickering, Matthew C, Lea, Susan M, Tang, Christoph M
Published in PLoS pathogens (01.10.2012)
Published in PLoS pathogens (01.10.2012)
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Development and validation of a nomogram to predict kidney survival at baseline in patients with C3 glomerulopathy
Caravaca-Fontán, Fernando, Rivero, Marta, Cavero, Teresa, Díaz-Encarnación, Montserrat, Cabello, Virginia, Ariceta, Gema, Quintana, Luis F, Marco, Helena, Barros, Xoana, Ramos, Natalia, Rodríguez-Mendiola, Nuria, Cruz, Sonia, Fernández-Juárez, Gema, Rodríguez, Adela, Pérez de José, Ana, Rabasco, Cristina, Rodado, Raquel, Fernández, Loreto, Pérez-Gómez, Vanessa, Ávila, Ana, Bravo, Luis, Espinosa, Natalia, Allende, Natalia, Sanchez de la Nieta, Maria Dolores, Rodríguez, Eva, Olea, Teresa, Melgosa, Marta, Huerta, Ana, Miquel, Rosa, Mon, Carmen, Fraga, Gloria, de Lorenzo, Alberto, Draibe, Juliana, González, Fayna, Shabaka, Amir, López-Rubio, Maria Esperanza, Fenollosa, María Ángeles, Martín-Penagos, Luis, Da Silva, Iara, Alonso Titos, Juana, Rodríguez de Córdoba, Santiago, Goicoechea de Jorge, Elena, Praga, Manuel
Published in Clinical kidney journal (01.09.2022)
Published in Clinical kidney journal (01.09.2022)
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Journal Article
The Development of Atypical Hemolytic Uremic Syndrome Depends on Complement C5
GOICOECHEA DE JORGE, Elena, MACOR, Paolo, PAIXAO-CAVALCANTE, Danielle, ROSE, Kirsten L, TEDESCO, Franco, TERENCE COOK, H, BOTTO, Marina, PICKERING, Matthew C
Published in Journal of the American Society of Nephrology (2011)
Published in Journal of the American Society of Nephrology (2011)
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Journal Article
Complement Factor H Binds to Denatured Rather than to Native Pentameric C-reactive Protein
Hakobyan, Svetlana, Harris, Claire L., van den Berg, Carmen W., Fernandez-Alonso, Maria Carmen, de Jorge, Elena Goicoechea, de Cordoba, Santiago Rodriguez, Rivas, German, Mangione, Palma, Pepys, Mark B., Morgan, B. Paul
Published in The Journal of biological chemistry (07.11.2008)
Published in The Journal of biological chemistry (07.11.2008)
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Journal Article
The Factor H protein family: The switchers of the complement alternative pathway
Lucientes‐Continente, Laura, Márquez‐Tirado, Bárbara, Goicoechea de Jorge, Elena
Published in Immunological reviews (01.01.2023)
Published in Immunological reviews (01.01.2023)
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Journal Article
Familial risk of developing atypical hemolytic-uremic syndrome
Arjona, Emilia, Huerta, Ana, Goicoechea de Jorge, Elena, Rodríguez de Córdoba, Santiago
Published in Blood (24.09.2020)
Published in Blood (24.09.2020)
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Journal Article
C3 glomerulopathy: consensus report
Pickering, Matthew C., D'Agati, Vivette D., Nester, Carla M., Smith, Richard J., Haas, Mark, Appel, Gerald B., Alpers, Charles E., Bajema, Ingeborg M., Bedrosian, Camille, Braun, Michael, Doyle, Mittie, Fakhouri, Fadi, Fervenza, Fernando C., Fogo, Agnes B., Frémeaux-Bacchi, Véronique, Gale, Daniel P., Goicoechea de Jorge, Elena, Griffin, Gene, Harris, Claire L., Michael Holers, V., Johnson, Sally, Lavin, Peter J., Medjeral-Thomas, Nicholas, Paul Morgan, B., Nast, Cynthia C., Noel, Laure-Hélène, Keith Peters, D., Rodríguez de Córdoba, Santiago, Servais, Aude, Sethi, Sanjeev, Song, Wen-Chao, Tamburini, Paul, Thurman, Joshua M., Zavros, Michael, Terence Cook, H.
Published in Kidney international (01.12.2013)
Published in Kidney international (01.12.2013)
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Journal Article
Conference Proceeding
A Hybrid CFHR3-1 Gene Causes Familial C3 Glomerulopathy
MALIK, Talat H, LAVIN, Peter J, PICKERING, Matthew C, GOICOECHEA DE JORGE, Elena, VERNON, Katherine A, ROSE, Kirsten L, PATEL, Mitali P, DE LEEUW, Marcel, NEARLY, John J, COLON, Peter J, WINN, Michelle P
Published in Journal of the American Society of Nephrology (01.07.2012)
Published in Journal of the American Society of Nephrology (01.07.2012)
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Journal Article
Defining the Glycosaminoglycan Interactions of Complement Factor H-Related Protein 5
Gyapon-Quast, Frederick, Goicoechea de Jorge, Elena, Malik, Talat, Wu, Nian, Yu, Jin, Chai, Wengang, Feizi, Ten, Liu, Yan, Pickering, Matthew C
Published in The Journal of immunology (1950) (15.07.2021)
Published in The Journal of immunology (1950) (15.07.2021)
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Journal Article
Complement alternative pathway determines disease susceptibility and severity in antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis
Lucientes-Continente, Laura, Fernández-Juárez, Gema, Márquez-Tirado, Bárbara, Jiménez-Villegas, Laura, Acevedo, Mercedes, Cavero, Teresa, Cámara, Luís Sánchez, Draibe, Juliana, Anton-Pampols, Paula, Caravaca-Fontán, Fernando, Praga, Manuel, Villacorta, Javier, Goicoechea de Jorge, Elena
Published in Kidney international (01.01.2024)
Published in Kidney international (01.01.2024)
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Journal Article
C3 glomerulopathy associated with monoclonal gammopathy: impact of chronic histologic lesions and beneficial effects of clone-targeted therapies
Caravaca-Fontán, Fernando, Lucientes, Laura, Serra, Núria, Cavero, Teresa, Rodado, Raquel, Ramos, Natalia, Gonzalez, Fayna, Shabaka, Amir, Cabello, Virginia, Huerta, Ana, Pampa-Saico, Saúl, Gutiérrez, Eduardo, Quintana, Luis F, López-Rubio, Maria Esperanza, Draibe, Juliana, Alonso Titos, Juana, Fernández-Juárez, Gema, Goicoechea de Jorge, Elena, Praga, Manuel
Published in Nephrology, dialysis, transplantation (19.10.2022)
Published in Nephrology, dialysis, transplantation (19.10.2022)
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Journal Article
Factor H-Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy
Márquez-Tirado, Bárbara, Gutiérrez-Tenorio, Josué, Tortajada, Agustín, Lucientes Continente, Laura, Caravaca-Fontán, Fernando, Malik, Talat H, Roldán Montero, Raquel, Elías, Sandra, Saiz Gonzalez, Ana, Fernández-Juarez, Gema, Sánchez-Corral, Pilar, Pickering, Matthew C, Praga, Manuel, Rodríguez de Córdoba, Santiago, Goicoechea de Jorge, Elena
Published in Journal of the American Society of Nephrology (01.06.2022)
Published in Journal of the American Society of Nephrology (01.06.2022)
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Journal Article