Agonist trapped in ATP-binding sites of the P2X2 receptor
Jiang, Ruotian, Lemoine, Damien, Martz, Adeline, Taly, Antoine, Gonin, Sophie, Prado de Carvalho, Lia, Specht, Alexandre, Grutter, Thomas
Published in Proceedings of the National Academy of Sciences - PNAS (31.05.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (31.05.2011)
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Nicotine Upregulates Its Own Receptors through Enhanced Intracellular Maturation
Sallette, Jérôme, Pons, Stéphanie, Devillers-Thiery, Anne, Soudant, Martine, Prado de Carvalho, Lia, Changeux, Jean-Pierre, Corringer, Pierre Jean
Published in Neuron (Cambridge, Mass.) (19.05.2005)
Published in Neuron (Cambridge, Mass.) (19.05.2005)
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A Putative Extracellular Salt Bridge at the Subunit Interface Contributes to the Ion Channel Function of the ATP-gated P2X2 Receptor
Jiang, Ruotian, Martz, Adeline, Gonin, Sophie, Taly, Antoine, de Carvalho, Lia Prado, Grutter, Thomas
Published in The Journal of biological chemistry (21.05.2010)
Published in The Journal of biological chemistry (21.05.2010)
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Implications of the Quaternary Twist Allosteric Model for the Physiology and Pathology of Nicotinic Acetylcholine Receptors
Taly, Antoine, Corringer, Pierre-Jean, Grutter, Thomas, de Carvalho, Lia Prado, Karplus, Martin, Changeux, Jean-Pierre
Published in Proceedings of the National Academy of Sciences - PNAS (07.11.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (07.11.2006)
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Molecular Tuning of Fast Gating in Pentameric Ligand-Gated Ion Channels
Grutter, Thomas, Lia Prado de Carvalho, Dufresne, Virginie, Antoine Taly, Edelstein, Stuart J., Changeux, Jean-Pierre
Published in Proceedings of the National Academy of Sciences - PNAS (13.12.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (13.12.2005)
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Pore Conformations and Gating Mechanism of a Cys-Loop Receptor
Paas, Yoav, Gilad Gibor, Grailhe, Regis, Nathalie Savatier-Duclert, Dufresne, Virginie, Morten Sunesen, Lia Prado de Carvalho, Changeux, Jean-Pierre, Attali, Bernard
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.2005)
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Mechanism of Cl- Selection by a Glutamate-gated Chloride (GluCl) Receptor Revealed through Mutations in the Selectivity Filter
Sunesen, Morten, de Carvalho, Lia Prado, Dufresne, Virginie, Grailhe, Regis, Savatier-Duclert, Nathalie, Gibor, Gilad, Peretz, Asher, Attali, Bernard, Changeux, Jean-Pierre, Paas, Yoav
Published in The Journal of biological chemistry (26.05.2006)
Published in The Journal of biological chemistry (26.05.2006)
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A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family
BOCQUET, Nicolas, PRADO DE CARVALHO, Lia, CARTAUD, Jean, NEYTON, Jacques, LE POUPON, Chantal, TALY, Antoine, GRUTTER, Thomas, CHANGEUX, Jean-Pierre, CORRINGER, Pierre-Jean
Published in Nature (04.01.2007)
Published in Nature (04.01.2007)
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Retrochalcone derivatives are positive allosteric modulators at synaptic and extrasynaptic GABAA receptors in vitro
Jiang, Ruotian, Miyamoto, Akiko, Martz, Adeline, Specht, Alexandre, Ishibashi, Hitoshi, Kueny‐Stotz, Marie, Chassaing, Stefan, Brouillard, Raymond, de Carvalho, Lia Prado, Goeldner, Maurice, Nabekura, Junichi, Nielsen, Mogens, Grutter, Thomas
Published in British journal of pharmacology (01.03.2011)
Published in British journal of pharmacology (01.03.2011)
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A chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels
Grutter, Thomas, de Carvalho, Lia Prado, Dufresne, Virginie, Taly, Antoine, Fischer, Markus, Changeux, Jean-Pierre
Published in Comptes rendus. Biologies (01.03.2005)
Published in Comptes rendus. Biologies (01.03.2005)
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Comparative models of P2X2 receptor support inter-subunit ATP-binding sites
Guerlet, Guillaume, Taly, Antoine, Prado de Carvalho, Lia, Martz, Adeline, Jiang, Ruotian, Specht, Alexandre, Novère, Nicolas Le, Grutter, Thomas
Published in Biochemical and biophysical research communications (24.10.2008)
Published in Biochemical and biophysical research communications (24.10.2008)
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An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors
Grutter, Thomas, Changeux, Jean-Pierre, Prado de Carvalho, Lia, Le Novère, Nicolas, Corringer, Pierre Jean, Edelstein, Stuart
Published in The EMBO journal (01.05.2003)
Published in The EMBO journal (01.05.2003)
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Distinct subcellular targeting of fluorescent nicotinic α3β4 and serotoninergic 5-HT3A receptors in hippocampal neurons
Grailhe, Régis, De Carvalho, Lia Prado, Paas, Yoav, Le Poupon, Chantal, Soudant, Martine, Bregestovski, Piotr, Changeux, Jean-Pierre, Corringer, Pierre-Jean
Published in The European journal of neuroscience (01.02.2004)
Published in The European journal of neuroscience (01.02.2004)
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Distinct subcellular targeting of fluorescent nicotinic alpha 3 beta 4 and serotoninergic 5-HT3A receptors in hippocampal neurons
Grailhe, Régis, de Carvalho, Lia Prado, Paas, Yoav, Le Poupon, Chantal, Soudant, Martine, Bregestovski, Piotr, Changeux, Jean-Pierre, Corringer, Pierre-Jean
Published in The European journal of neuroscience (01.02.2004)
Published in The European journal of neuroscience (01.02.2004)
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Identification of two critical residues within the Cys-loop sequence that determine fast-gating kinetics in a pentameric ligand-gated ion channel
Grutter, Thomas, de Carvalho, Lia Prado, Dufresne, Virginie, Taly, Antoine, Changeux, Jean-Pierre
Published in Journal of molecular neuroscience (01.01.2006)
Published in Journal of molecular neuroscience (01.01.2006)
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3-Amino-.beta.-carboline derivatives and the benzodiazepine receptor. Synthesis of a selective antagonist of the sedative action of diazepam
Dodd, Robert H, Ouannes, Catherine, Prado de Carvalho, Lia, Valin, Anne, Venault, Patrice, Chapouthier, Georges, Rossier, Jean, Potier, Pierre
Published in Journal of medicinal chemistry (01.06.1985)
Published in Journal of medicinal chemistry (01.06.1985)
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Synthetic Routes to 4-Amino-3-carboxy-.beta.-carboline Derivatives: Incidental Formation of Novel Furo[3,4-c]-.beta.-carbolin-2-ones Displaying High Affinities for the Benzodiazepine Receptor
Dorey, Gilbert, Dubois, Laurent, Prado de Carvalho, Lia Prdo, Potier, Pierre, Dodd, Robert H
Published in Journal of medicinal chemistry (01.01.1995)
Published in Journal of medicinal chemistry (01.01.1995)
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Anxiogenic and non-anxiogenic benzodiazepine antagonists
Prado de Carvalho, L P, Grecksch, G, Chapouthier, G, Rossier, J
Published in Nature (London) (01.01.1983)
Published in Nature (London) (01.01.1983)
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Journal Article
Retrochalcone derivatives are positive allosteric modulators at synaptic and extrasynaptic GABA(A) receptors in vitro
Jiang, Ruotian, Miyamoto, Akiko, Martz, Adeline, Specht, Alexandre, Ishibashi, Hitoshi, Kueny-Stotz, Marie, Chassaing, Stefan, Brouillard, Raymond, de Carvalho, Lia Prado, Goeldner, Maurice, Nabekura, Junichi, Nielsen, Mogens, Grutter, Thomas
Published in British journal of pharmacology (01.03.2011)
Published in British journal of pharmacology (01.03.2011)
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How many NMDA receptors?
LAMBOLEZ, BERTRAND, CURUTCHET, PASCALE, STINNAKRE, JACQUES, BREGESTOVSKI, PIOTR, ROSSIER, JEAN, CARVALHO, LIA PRADO DE
Published in Nature (London) (06.09.1990)
Published in Nature (London) (06.09.1990)
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