Antinociceptive effects of new pyrazoles compounds mediated by the ASIC-1α channel, TRPV-1 and μMOR receptors
Florentino, Iziara F., Silva, Daiany P.B., Cardoso, Carina Sofia, Menegatti, Ricardo, de Carvalho, Flávio S., Lião, Luciano M., Pinto, Paulo M., Peigneur, Steve, Costa, Elson A., Tytgat, Jan
Published in Biomedicine & pharmacotherapy (01.07.2019)
Published in Biomedicine & pharmacotherapy (01.07.2019)
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Comparison of Conventional and Microwave Synthesis of Phenyl-1H-pyrazoles and Phenyl-1H-pyrazoles-4-carboxylic Acid Derivatives
Machado, Antônio S, de Carvalho, Flávio S, Mouraa, Rayssa B P, Chaves, Lorrayne S, Lião, Luciano M, Sanz, Germãn, Vaz, Boniek G, Rodrigues, Marcella F, Romão, Wanderson, Menegatti, Ricardo, Silva, Gloria N S
Published in Current organic synthesis (01.01.2021)
Published in Current organic synthesis (01.01.2021)
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Preclinical pharmacokinetics of a promising antineoplastic prototype piperazine-containing compound (LQFM018) in rats by a new LC-MS/MS bioanalytical method
Rodrigues, Andryne R., Rodrigues, Caroline R., Gomes, Sandro A., Marques, Stefanne M., Naves, Lara M., Pedrino, Gustavo R., de Oliveira-Neto, Jerônimo R., de Carvalho, Flávio S., Cruz, Alessandro, Lião, Luciano M., Menegatti, Ricardo, Carlos da Cunha, Luiz
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.05.2023)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.05.2023)
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Neuropharmacological Activity of the New Piperazine Derivative 2-(4-((1- Phenyl-1H-Pyrazol-4-yl)Methyl)Piperazin-1-yl)Ethyl Acetate is Modulated by Serotonergic and GABAergic Pathways
Almeida, Lorena de Souza, Santana, Ianca Gontijo Cavalcante, da Silva Moreira, Lorrane Kelle, Turones, Larissa Córdova, Sanz, Germán, Vaz, Boniek G, de Carvalho, Flávio S, Lião, Luciano M, Menegatti, Ricardo, Costa, Elson Alves, de Brito, Adriane Ferreira
Published in CNS & neurological disorders drug targets (01.01.2022)
Published in CNS & neurological disorders drug targets (01.01.2022)
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Anti-inflammatory, antinociceptive, and vasorelaxant effects of a new pyrazole compound 5-(1-(2-fluorophenyl)-1H-pyrazol-4-yl)-1H-tetrazole: role of NO/cGMP pathway and calcium channels
de Oliveira, Lanussy P, Florentino, Iziara F, Silva, Daiany PB, Pazini, Francine, de Carvalho, Flávio S, Sanz, Germán, Vaz, Boniek G, da Rocha, Fábio F, Fajemiroye, James O, Ghedini, Paulo C, Lião, Luciano M, Menegatti, Ricardo, Costa, Elson A, de Oliveira, Thiago S
Published in Canadian journal of physiology and pharmacology (01.05.2023)
Published in Canadian journal of physiology and pharmacology (01.05.2023)
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Toxico-pharmacological evaluations of the small-molecule LQFM166: Inducer of apoptosis and MDM2 antagonist
dos Santos, Thaís Rosa Marques, Garcia da Silva, Artur Christian, de Carvalho, Flávio S., Sanz, Germán, Vaz, Boniek G., Lião, Luciano M., Menegatti, Ricardo, Valadares, Marize Campos
Published in Chemico-biological interactions (25.09.2018)
Published in Chemico-biological interactions (25.09.2018)
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A new piperazine derivative: 1-(4-(3,5-di-tert-butyl-4-hydroxybenzyl) piperazin-1-yl)-2-methoxyethan-1-one with antioxidant and central activity
Brito, Adriane F., Braga, Patrícia C. C. S., Moreira, Lorrane K. S., Silva, Dayane M., Silva, Daiany P. B., Sanz, Germán, Vaz, Boniek G., de Carvalho, Flávio S., Lião, Luciano M., Silva, Rafaela R., Noël, François, Neri, Hiasmin F. S., Ghedini, Paulo C., de Carvalho, Murilo F., de S. Gil, Eric, Costa, Elson A., Menegatti, Ricardo
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.03.2018)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.03.2018)
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HPLC-PDA method validated for the determination of hibalactone in Hydrocotyle umbellata subterraneous parts and its ultrasound-assisted extraction optimization
Oliveira, Matheus G. de, Almeida, Paulo H.G. de, Oliveira, Thiago L.S., Silva, Liliane de S., Carvalho, Flávio S. de, Alves, Suzana F., Borges, Leonardo L., Santos, Pierre A. dos, Silva, Vinicius B. da, Paula, José R. de
Published in Revista brasileira de farmacognosia (01.03.2019)
Published in Revista brasileira de farmacognosia (01.03.2019)
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Anxiolytic‐like effect of 2‐(4‐((1‐phenyl‐1H‐pyrazol‐4‐yl)methyl)piperazin‐1‐yl)ethan‐1‐ol is mediated through the benzodiazepine and nicotinic pathways
Brito, Adriane F., Fajemiroye, James O., Neri, Hiasmin F. S., Silva, Dayane M., Silva, Daiany P. B., Sanz, Germán, Vaz, Boniek G., Carvalho, Flávio S., Ghedini, Paulo C., Lião, Luciano M., Menegatti, Ricardo, Costa, Elson A.
Published in Chemical biology & drug design (01.09.2017)
Published in Chemical biology & drug design (01.09.2017)
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Design, synthesis and pharmacological assessment of new pyrazole compounds
Oliveria, Jordana C., Silva, Daiany P. B., Florentino, Iziara F., da Silva, Lidya C., Sanz, Germán, Vaz, Boniek G., Pazini, Francine, de Carvalho, Flávio S., Lião, Luciano M., dos Santos, Thaís Rosa Marques, Valadares, Marize C., Costa, Elson A., dos Santos, Fernanda Cristina Alcantara, Villavicencio, Bianca, Verli, Hugo, Menegatti, Ricardo
Published in Inflammopharmacology (01.08.2020)
Published in Inflammopharmacology (01.08.2020)
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Induction of apoptosis in Ehrlich ascites tumour cells via p53 activation by a novel small-molecule MDM2 inhibitor - LQFM030
da Mota, Mariana F, Cortez, Alane P, Benfica, Polyana L, Rodrigues, Bruna Dos S, Castro, Thalyta F, Macedo, Larissa M, Castro, Carlos H, Lião, Luciano M, de Carvalho, Flávio S, Romeiro, Luiz A S, Menegatti, Ricardo, Verli, Hugo, Villavicencio, Bianca, Valadares, Marize C
Published in Journal of pharmacy and pharmacology (01.09.2016)
Published in Journal of pharmacy and pharmacology (01.09.2016)
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Chemoprotective effect of the tetrahydrofuran lignan grandisin in the in-vivo rodent micronucleus assay
Valadares, Marize C, de Oliveira, Jr, Luiz Marcos, de Carvalho, Flávio S, Andrade, Lorenna V S, dos Santos, Alexandre P, de Oliveira, Valéria, Gil, Eric de Souza, Kato, Massuo J
Published in Journal of pharmacy and pharmacology (01.03.2011)
Published in Journal of pharmacy and pharmacology (01.03.2011)
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Anti-inflammatory, antinociceptive, and vasorelaxant effects of a new pyrazole compound 5-(1-(2-fluorophenyl)-1 H -pyrazol-4-yl)-1 H -tetrazole: role of NO/cGMP pathway and calcium channels
de Oliveira, Lanussy P, Florentino, Iziara F, Silva, Daiany P B, Pazini, Francine, de Carvalho, Flávio S, Sanz, Germán, Vaz, Boniek G, da Rocha, Fábio F, Fajemiroye, James O, Ghedini, Paulo C, Lião, Luciano M, Menegatti, Ricardo, Costa, Elson A, de Oliveira, Thiago S
Published in Canadian journal of physiology and pharmacology (01.05.2023)
Published in Canadian journal of physiology and pharmacology (01.05.2023)
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The novel piperazine-containing compound LQFM018: Necroptosis cell death mechanisms, dopamine D 4 receptor binding and toxicological assessment
Costa, Fabiana Bettanin, Cortez, Alane P, de Ávila, Renato Ivan, de Carvalho, Flávio S, Andrade, Wanessa M, da Cruz, Andrezza F, Reis, Karinna B, Menegatti, Ricardo, Lião, Luciano M, Romeiro, Luiz Antônio S, Noël, François, Fraga, Carlos Alberto M, Barreiro, Eliezer J, Sanz, Germán, Rodrigues, Marcella F, Vaz, Boniek G, Valadares, Marize Campos
Published in Biomedicine & pharmacotherapy (01.06.2018)
Published in Biomedicine & pharmacotherapy (01.06.2018)
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The novel piperazine-containing compound LQFM018: Necroptosis cell death mechanisms, dopamine D4 receptor binding and toxicological assessment
Costa, Fabiana Bettanin, Cortez, Alane P., de Ávila, Renato Ivan, de Carvalho, Flávio S., Andrade, Wanessa M., da Cruz, Andrezza F., Reis, Karinna B., Menegatti, Ricardo, Lião, Luciano M., Romeiro, Luiz Antônio S., Noël, François, Fraga, Carlos Alberto M., Barreiro, Eliezer J., Sanz, Germán, Rodrigues, Marcella F., Vaz, Boniek G., Valadares, Marize Campos
Published in Biomedicine & pharmacotherapy (01.06.2018)
Published in Biomedicine & pharmacotherapy (01.06.2018)
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Surface structure and reactivity study of phosphotungstic acid-nitrogenated ormosils
Ferreira-Neto, Elias P., de Carvalho, Flavio L. S., Ullah, Sajjad, Zoldan, Vinicius C., Pasa, André A., de Souza, Adriano Lopes, Battirola, Liliane C., Rudolf, Petra, Bilmes, Sara Aldabe, Rodrigues-Filho, Ubirajara P.
Published in Journal of sol-gel science and technology (01.06.2013)
Published in Journal of sol-gel science and technology (01.06.2013)
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Anti-inflammatory, antinociceptive, and vasorelaxant effects of a new pyrazole compound 5--1H-tetrazole: role of NO/cGMP pathway and calcium channels
de Oliveira, Lanussy P, Florentino, Iziara F, Silva, Daiany P.B, Pazini, Francine, de Carvalho, Flavio S, Sanz, German, Vaz, Boniek G, da Rocha, Fabio F, Fajemiroye, James O, Ghedini, Paulo C, Liao, Luciano M, Menegatti, Ricardo, Costa, Elson A, de Oliveira, Thiago S
Published in Canadian journal of physiology and pharmacology (01.05.2023)
Published in Canadian journal of physiology and pharmacology (01.05.2023)
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Preparation, characterization and photochromic behavior of phosphotungstic acid-ormosil nanocomposites
Ferreira-Neto, Elias P., Ullah, Sajjad, de Carvalho, Flavio L.S., de Souza, Adriano L., de Oliveira, Marcos, Schneider, José F., Mascarenhas, Yvonne P., Jorge, Alberto M., Rodrigues-Filho, Ubirajara P.
Published in Materials chemistry and physics (01.03.2015)
Published in Materials chemistry and physics (01.03.2015)
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Physicochemical characterization and analgesic effect of inclusion complexes of essential oil from Hyptis pectinata L. Poit leaves with β-cyclodextrin
Menezes, Paula dos P, Araujo, Adriano A de S, Doria, Grace Anne A, Quintans-Junior, Lucindo J, de Oliveira, Makson G B, dos Santos, Marcio R V, de Oliveira, Juliana F, Matos, Jivaldo do R, Carvalho, Flavio M de S, Alves, Pericles B, de Matos, Iara L, dos Santos, Darlisson A, Marreto, Ricardo N, da Silva, Gabriel F, Serafini, Mairim R
Published in Current pharmaceutical biotechnology (01.01.2015)
Published in Current pharmaceutical biotechnology (01.01.2015)
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