Pleiotropic Roles of Bile Acids in Metabolism
de Aguiar Vallim, Thomas Q., Tarling, Elizabeth J., Edwards, Peter A.
Published in Cell metabolism (07.05.2013)
Published in Cell metabolism (07.05.2013)
Get full text
Journal Article
NOTCH1 is a mechanosensor in adult arteries
Mack, Julia J., Mosqueiro, Thiago S., Archer, Brian J., Jones, William M., Sunshine, Hannah, Faas, Guido C., Briot, Anais, Aragón, Raquel L., Su, Trent, Romay, Milagros C., McDonald, Austin I., Kuo, Cheng-Hsiang, Lizama, Carlos O., Lane, Timothy F., Zovein, Ann C., Fang, Yun, Tarling, Elizabeth J., de Aguiar Vallim, Thomas Q., Navab, Mohamad, Fogelman, Alan M., Bouchard, Louis S., Iruela-Arispe, M. Luisa
Published in Nature communications (20.11.2017)
Published in Nature communications (20.11.2017)
Get full text
Journal Article
MAFG Is a Transcriptional Repressor of Bile Acid Synthesis and Metabolism
de Aguiar Vallim, Thomas Q., Tarling, Elizabeth J., Ahn, Hannah, Hagey, Lee R., Romanoski, Casey E., Lee, Richard G., Graham, Mark J., Motohashi, Hozumi, Yamamoto, Masayuki, Edwards, Peter A.
Published in Cell metabolism (03.02.2015)
Published in Cell metabolism (03.02.2015)
Get full text
Journal Article
Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation
Bennett, Brian J., Vallim, Thomas Q. de Aguiar, Wang, Zeneng, Shih, Diana M., Meng, Yonghong, Gregory, Jill, Allayee, Hooman, Lee, Richard, Graham, Mark, Crooke, Rosanne, Edwards, Peter A., Hazen, Stanley L., Lusis, Aldons J.
Published in Cell metabolism (08.01.2013)
Published in Cell metabolism (08.01.2013)
Get full text
Journal Article
SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression[S]
Vergnes, Laurent, Chin, Robert G., de Aguiar Vallim, Thomas, Fong, Loren G., Osborne, Timothy F., Young, Stephen G., Reue, Karen
Published in Journal of lipid research (01.03.2016)
Published in Journal of lipid research (01.03.2016)
Get full text
Journal Article
Role of ABC transporters in lipid transport and human disease
Tarling, Elizabeth J, Vallim, Thomas Q. de Aguiar, Edwards, Peter A
Published in Trends in endocrinology and metabolism (01.07.2013)
Published in Trends in endocrinology and metabolism (01.07.2013)
Get full text
Journal Article
Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants[S]
Lee, Jessica M., Ong, Jessica R., Vergnes, Laurent, de Aguiar Vallim, Thomas Q., Nolan, Jonathan, Cantor, Rita M., Walters, JulianR.F., Reue, Karen
Published in Journal of lipid research (01.03.2018)
Published in Journal of lipid research (01.03.2018)
Get full text
Journal Article
ABCG1 regulates pulmonary surfactant metabolism in mice and men[S]
de Aguiar Vallim, Thomas Q., Lee, Elinor, Merriott, David J., Goulbourne, Christopher N., Cheng, Joan, Cheng, Angela, Gonen, Ayelet, Allen, Ryan M., Palladino, Elisa N.D., Ford, David A., Wang, Tisha, Baldán, Ángel, Tarling, Elizabeth J.
Published in Journal of lipid research (01.05.2017)
Published in Journal of lipid research (01.05.2017)
Get full text
Journal Article
An integrative systems genetic analysis of mammalian lipid metabolism
Parker, Benjamin L., Calkin, Anna C., Seldin, Marcus M., Keating, Michael F., Tarling, Elizabeth J., Yang, Pengyi, Moody, Sarah C., Liu, Yingying, Zerenturk, Eser J., Needham, Elise J., Miller, Matthew L., Clifford, Bethan L., Morand, Pauline, Watt, Matthew J., Meex, Ruth C. R., Peng, Kang-Yu, Lee, Richard, Jayawardana, Kaushala, Pan, Calvin, Mellett, Natalie A., Weir, Jacquelyn M., Lazarus, Ross, Lusis, Aldons J., Meikle, Peter J., James, David E., de Aguiar Vallim, Thomas Q., Drew, Brian G.
Published in Nature (London) (01.03.2019)
Published in Nature (London) (01.03.2019)
Get full text
Journal Article
Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis
Anastasia, Irene, Ilacqua, Nicolò, Raimondi, Andrea, Lemieux, Philippe, Ghandehari-Alavijeh, Rana, Faure, Guilhem, Mekhedov, Sergei L., Williams, Kevin J., Caicci, Federico, Valle, Giorgio, Giacomello, Marta, Quiroga, Ariel D., Lehner, Richard, Miksis, Michael J., Toth, Katalin, de Aguiar Vallim, Thomas Q., Koonin, Eugene V., Scorrano, Luca, Pellegrini, Luca
Published in Cell reports (Cambridge) (16.03.2021)
Published in Cell reports (Cambridge) (16.03.2021)
Get full text
Journal Article
MicroRNA-144 Regulates Hepatic ATP Binding Cassette Transporter A1 and Plasma High-Density Lipoprotein After Activation of the Nuclear Receptor Farnesoid X Receptor
de Aguiar Vallim, Thomas Q, Tarling, Elizabeth J, Kim, Tammy, Civelek, Mete, Baldán, Ángel, Esau, Christine, Edwards, Peter A
Published in Circulation research (07.06.2013)
Published in Circulation research (07.06.2013)
Get full text
Journal Article
Intestinal Phospholipid Remodeling Is Required for Dietary-Lipid Uptake and Survival on a High-Fat Diet
Wang, Bo, Rong, Xin, Duerr, Mark A., Hermanson, Daniel J., Hedde, Per Niklas, Wong, Jinny S., de Aguiar Vallim, Thomas Q., Cravatt, Benjamin F., Gratton, Enrico, Ford, David A., Tontonoz, Peter
Published in Cell metabolism (08.03.2016)
Published in Cell metabolism (08.03.2016)
Get full text
Journal Article
Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP
Zhang, Li, Rajbhandari, Prashant, Priest, Christina, Sandhu, Jaspreet, Wu, Xiaohui, Temel, Ryan, Castrillo, Antonio, de Aguiar Vallim, Thomas Q, Sallam, Tamer, Tontonoz, Peter
Published in eLife (25.10.2017)
Published in eLife (25.10.2017)
Get full text
Journal Article
RNA-binding protein ZFP36L1 maintains posttranscriptional regulation of bile acid metabolism
Tarling, Elizabeth J, Clifford, Bethan L, Cheng, Joan, Morand, Pauline, Cheng, Angela, Lester, Ellen, Sallam, Tamer, Turner, Martin, de Aguiar Vallim, Thomas Q
Published in The Journal of clinical investigation (01.10.2017)
Published in The Journal of clinical investigation (01.10.2017)
Get full text
Journal Article
Alveolar macrophage lipid burden correlates with clinical improvement in patients with pulmonary alveolar proteinosis
Lee, Elinor, Williams, Kevin J., McCarthy, Cormac, Bridges, James P., Redente, Elizabeth F., de Aguiar Vallim, Thomas Q., Barrington, Robert A., Wang, Tisha, Tarling, Elizabeth J.
Published in Journal of lipid research (01.02.2024)
Published in Journal of lipid research (01.02.2024)
Get full text
Journal Article
Deletion of Trim28 in committed adipocytes promotes obesity but preserves glucose tolerance
Bond, Simon T., King, Emily J., Henstridge, Darren C., Tran, Adrian, Moody, Sarah C., Yang, Christine, Liu, Yingying, Mellett, Natalie A., Nath, Artika P., Inouye, Michael, Tarling, Elizabeth J., de Aguiar Vallim, Thomas Q., Meikle, Peter J., Calkin, Anna C., Drew, Brian G.
Published in Nature communications (04.01.2021)
Published in Nature communications (04.01.2021)
Get full text
Journal Article
Acute activation of adipocyte lipolysis reveals dynamic lipid remodeling of the hepatic lipidome
Zhang, Sicheng, Williams, Kevin J., Verlande-Ferrero, Amandine, Chan, Alvin P., Su, Gino B., Kershaw, Erin E., Cox, James E., Maschek, John Alan, Shapira, Suzanne N., Christofk, Heather R., de Aguiar Vallim, Thomas Q., Masri, Selma, Villanueva, Claudio J.
Published in Journal of lipid research (01.02.2024)
Published in Journal of lipid research (01.02.2024)
Get full text
Journal Article
ZFP36-mediated mRNA decay regulates metabolism
Cicchetto, Andrew C., Jacobson, Elsie C., Sunshine, Hannah, Wilde, Blake R., Krall, Abigail S., Jarrett, Kelsey E., Sedgeman, Leslie, Turner, Martin, Plath, Kathrin, Iruela-Arispe, M. Luisa, de Aguiar Vallim, Thomas Q., Christofk, Heather R.
Published in Cell reports (Cambridge) (30.05.2023)
Published in Cell reports (Cambridge) (30.05.2023)
Get full text
Journal Article
Expression of Synj2bp in mouse liver regulates the extent of wrappER-mitochondria contact to maintain hepatic lipid homeostasis
Ilacqua, Nicolò, Anastasia, Irene, Aloshyn, Danylo, Ghandehari-Alavijeh, Rana, Peluso, Emily Ann, Brearley-Sholto, Madelaine C, Pellegrini, Leonardo V, Raimondi, Andrea, de Aguiar Vallim, Thomas Q, Pellegrini, Luca
Published in Biology direct (01.12.2022)
Published in Biology direct (01.12.2022)
Get full text
Journal Article