Structural basis for human coronavirus attachment to sialic acid receptors
Tortorici, M. Alejandra, Walls, Alexandra C., Lang, Yifei, Wang, Chunyan, Li, Zeshi, Koerhuis, Danielle, Boons, Geert-Jan, Bosch, Berend-Jan, Rey, Félix A., de Groot, Raoul J., Veesler, David
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Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses
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SARS-CoV-2 nucleocapsid protein inhibits the PKR-mediated integrated stress response through RNA-binding domain N2b
Aloise, Chiara, Schipper, Jelle G, van Vliet, Arno, Oymans, Judith, Donselaar, Tim, Hurdiss, Daniel L, de Groot, Raoul J, van Kuppeveld, Frank J. M
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Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans
Hurdiss, Daniel L., Drulyte, Ieva, Lang, Yifei, Shamorkina, Tatiana M., Pronker, Matti F., van Kuppeveld, Frank J. M., Snijder, Joost, de Groot, Raoul J.
Published in Nature communications (16.09.2020)
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Structure of Coronavirus Hemagglutinin-Esterase Offers Insight into Corona and Influenza Virus Evolution
Zeng, Qinghong, Langereis, Martijn A., van Vliet, Arno L. W., Huizinga, Eric G., de Groot, Raoul J.
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.2008)
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Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes
Wang, Chunyan, Hesketh, Emma L., Shamorkina, Tatiana M., Li, Wentao, Franken, Peter J., Drabek, Dubravka, van Haperen, Rien, Townend, Sarah, van Kuppeveld, Frank J. M., Grosveld, Frank, Ranson, Neil A., Snijder, Joost, de Groot, Raoul J., Hurdiss, Daniel L., Bosch, Berend-Jan
Published in Nature communications (25.05.2022)
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The murine coronavirus hemagglutinin-esterase receptor-binding site: a major shift in ligand specificity through modest changes in architecture
Langereis, Martijn A, Zeng, Qinghong, Heesters, Balthasar A, Heesters, Balthasar, Huizinga, Eric G, de Groot, Raoul J
Published in PLoS pathogens (01.01.2012)
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Small molecule ISRIB suppresses the integrated stress response within a defined window of activation
Rabouw, Huib H., Langereis, Martijn A., Anand, Aditya A., Visser, Linda J., de Groot, Raoul J., Walter, Peter, van Kuppeveld, Frank J. M.
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2019)
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Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A
Hulswit, Ruben J. G., Lang, Yifei, Bakkers, Mark J. G., Li, Wentao, Li, Zeshi, Schouten, Arie, Ophorst, Bram, van Kuppeveld, Frank J. M., Boons, Geert-Jan, Bosch, Berend-Jan, Huizinga, Eric G., de Groot, Raoul J.
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Published in Proceedings of the National Academy of Sciences - PNAS (12.02.2019)
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Isolation of reovirus T3D mutants capable of infecting human tumor cells independent of junction adhesion molecule-A
van den Wollenberg, Diana J M, Dautzenberg, Iris J C, van den Hengel, Sanne K, Cramer, Steve J, de Groot, Raoul J, Hoeben, Rob C
Published in PloS one (24.10.2012)
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Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein
Li, Wentao, Hulswit, Ruben J. G., Widjaja, Ivy, Raj, V. Stalin, McBride, Ryan, Peng, Wenjie, Widagdo, W., Tortorici, M. Alejandra, van Dieren, Brenda, Lang, Yifei, van Lent, Jan W. M., Paulson, James C., de Haan, Cornelis A. M., de Groot, Raoul J., van Kuppeveld, Frank J. M., Haagmans, Bart L., Bosch, Berend-Jan
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Published in Proceedings of the National Academy of Sciences - PNAS (03.10.2017)
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Foot-and-Mouth Disease Virus Leader Protease Cleaves G3BP1 and G3BP2 and Inhibits Stress Granule Formation
Visser, Linda J, Medina, Gisselle N, Rabouw, Huib H, de Groot, Raoul J, Langereis, Martijn A, de Los Santos, Teresa, van Kuppeveld, Frank J M
Published in Journal of virology (15.01.2019)
Published in Journal of virology (15.01.2019)
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Synthetic O-acetylated sialosides facilitate functional receptor identification for human respiratory viruses
Li, Zeshi, Lang, Yifei, Liu, Lin, Bunyatov, Mehman I., Sarmiento, Angelic Isaza, de Groot, Raoul J., Boons, Geert-Jan
Published in Nature chemistry (01.05.2021)
Published in Nature chemistry (01.05.2021)
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Coronavirus hemagglutinin-esterase and spike proteins coevolve for functional balance and optimal virion avidity
Lang, Yifei, Li, Wentao, Li, Zeshi, Koerhuis, Danielle, van den Burg, Arthur C. S., Rozemuller, Erik, Bosch, Berend-Jan, van Kuppeveld, Frank J. M., Boons, Geert-Jan, Huizinga, Eric G., van der Schaar, Hilde M., de Groot, Raoul J.
Published in Proceedings of the National Academy of Sciences - PNAS (13.10.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (13.10.2020)
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Essential Role of Enterovirus 2A Protease in Counteracting Stress Granule Formation and the Induction of Type I Interferon
Visser, Linda J, Langereis, Martijn A, Rabouw, Huib H, Wahedi, Maryam, Muntjewerff, Elke M, de Groot, Raoul J, van Kuppeveld, Frank J M
Published in Journal of virology (15.05.2019)
Published in Journal of virology (15.05.2019)
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Betacoronavirus Adaptation to Humans Involved Progressive Loss of Hemagglutinin-Esterase Lectin Activity
Bakkers, Mark J.G., Lang, Yifei, Feitsma, Louris J., Hulswit, Ruben J.G., de Poot, Stefanie A.H., van Vliet, Arno L.W., Margine, Irina, de Groot-Mijnes, Jolanda D.F., van Kuppeveld, Frank J.M., Langereis, Martijn A., Huizinga, Eric G., de Groot, Raoul J.
Published in Cell Host & Microbe (08.03.2017)
Published in Cell Host & Microbe (08.03.2017)
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Cross-comparison of Protein Recognition of Sialic Acid Diversity on Two Novel Sialoglycan Microarrays
Padler-Karavani, Vered, Song, Xuezheng, Yu, Hai, Hurtado-Ziola, Nancy, Huang, Shengshu, Muthana, Saddam, Chokhawala, Harshal A., Cheng, Jiansong, Verhagen, Andrea, Langereis, Martijn A., Kleene, Ralf, Schachner, Melitta, de Groot, Raoul J., Lasanajak, Yi, Matsuda, Haruo, Schwab, Richard, Chen, Xi, Smith, David F., Cummings, Richard D., Varki, Ajit
Published in The Journal of biological chemistry (29.06.2012)
Published in The Journal of biological chemistry (29.06.2012)
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Feline infectious peritonitis: insights into feline coronavirus pathobiogenesis and epidemiology based on genetic analysis of the viral 3c gene
Chang, Hui-Wen, Groot, Raoul J. de, Egberink, Herman F, Rottier, Peter J.M
Published in Journal of general virology (01.02.2010)
Published in Journal of general virology (01.02.2010)
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Specific, Sensitive, High-Resolution Detection of Protein Molecules in Eukaryotic Cells Using Metal-Tagging Transmission Electron Microscopy
Risco, Cristina, Sanmartín-Conesa, Eva, Tzeng, Wen-Pin, Frey, Teryl K., Seybold, Volker, de Groot, Raoul J.
Published in Structure (London) (09.05.2012)
Published in Structure (London) (09.05.2012)
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