The Friedreich ataxia GAA repeat expansion mutation induces comparable epigenetic changes in human and transgenic mouse brain and heart tissues
Al-Mahdawi, Sahar, Pinto, Ricardo Mouro, Ismail, Ozama, Varshney, Dhaval, Lymperi, Stefania, Sandi, Chiranjeevi, Trabzuni, Daniah, Pook, Mark
Published in Human molecular genetics (01.03.2008)
Published in Human molecular genetics (01.03.2008)
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Interferon gamma as a potential therapy for Friedreich ataxia
Arcuri, G, Fortuni, S, Sandi, C, Ezzatizadeh, V, Casali, C, Condo, I, Malisan, F, Al-Mahdawi, S, Pook, M, Testi, R
Published in Journal of the neurological sciences (15.10.2013)
Published in Journal of the neurological sciences (15.10.2013)
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Polyaniline doping with nanoparticles: A review on the potential of electrical properties
Al-Obaidi, N S, Al-Garawi, Z S, Al-Mahdawi, A S
Published in Journal of physics. Conference series (01.03.2021)
Published in Journal of physics. Conference series (01.03.2021)
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GAA repeat expansion mutation mouse models of Friedreich ataxia exhibit oxidative stress leading to progressive neuronal and cardiac pathology
Al-Mahdawi, Sahar, Pinto, Ricardo Mouro, Varshney, Dhaval, Lawrence, Lorraine, Lowrie, Margaret B., Hughes, Sian, Webster, Zoe, Blake, Julian, Cooper, J. Mark, King, Rosalind, Pook, Mark A.
Published in Genomics (San Diego, Calif.) (01.11.2006)
Published in Genomics (San Diego, Calif.) (01.11.2006)
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Interferon gamma upregulates frataxin and corrects the functional deficits in a Friedreich ataxia model
TOMASSINI, Barbara, ARCURI, Gaetano, TESTI, Roberto, FORTUNI, Silvia, SANDI, Chiranjeevi, EZZATIZADEH, Vahid, CASALI, Carlo, CONDO, Ivano, MALISAN, Florence, AL-MAHDAWI, Sahar, POOK, Mark
Published in Human molecular genetics (01.07.2012)
Published in Human molecular genetics (01.07.2012)
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The electrocardiogram is a more sensitive indicator than echocardiography of hypertrophic cardiomyopathy in families with a mutation in the MYH7 gene
al-Mahdawi, S, Chamberlain, S, Chojnowska, L, Michalak, E, Nihoyannopoulos, P, Ryan, M, Kusnierczyk, B, French, J A, Gilligan, D M, Cleland, J
Published in British Heart Journal (01.08.1994)
Published in British Heart Journal (01.08.1994)
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Parathyroid hormone related peptide gene expression in human fetal and adult heart
Bui, T D, Shallal, A, Malik, A N, Al-Mahdawi, S, Moscoso, G, Bailey, M E S, Burton, P B J, Moniz, C
Published in Cardiovascular research (01.07.1993)
Published in Cardiovascular research (01.07.1993)
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Identification of a mutation in the beta cardiac myosin heavy chain gene in a family with hypertrophic cardiomyopathy
al-Mahdawi, S, Chamberlain, S, Cleland, J, Nihoyannopoulos, P, Gilligan, D, French, J, Choudhury, L, Williamson, R, Oakley, C
Published in British Heart Journal (01.02.1993)
Published in British Heart Journal (01.02.1993)
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Somatic instability of the expanded GAA triplet-repeat sequence in Friedreich ataxia progresses throughout life
De Biase, Irene, Rasmussen, Astrid, Monticelli, Antonella, Al-Mahdawi, Sahar, Pook, Mark, Cocozza, Sergio, Bidichandani, Sanjay I.
Published in Genomics (San Diego, Calif.) (01.07.2007)
Published in Genomics (San Diego, Calif.) (01.07.2007)
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The GAA triplet-repeat is unstable in the context of the human FXN locus and displays age-dependent expansions in cerebellum and DRG in a transgenic mouse model
CLARK, Rhonda M, DE BIASE, Irene, MALYKHINA, Anna P, AL-MAHDAWI, Sahar, POOK, Mark, BIDICHANDANI, Sanjay I
Published in Human genetics (01.01.2007)
Published in Human genetics (01.01.2007)
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YAC transgenic mice carrying pathological alleles of the MJD1 locus exhibit a mild and slowly progressive cerebellar deficit
Cemal, Cemal K., Carroll, Christopher J., Lawrence, Lorraine, Lowrie, Margaret B., Ruddle, Piers, Al-Mahdawi, Sahar, King, Rosalind H.M., Pook, Mark A., Huxley, Clare, Chamberlain, Susan
Published in Human molecular genetics (01.05.2002)
Published in Human molecular genetics (01.05.2002)
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