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POS0672 FIRST-IN-HUMAN STUDY OF GS-5718, AN ORAL IRAK-4 INHIBITOR, IN HEALTHY SUBJECTS: PHARMACOKINETICS, SAFETY, TOLERABILITY, AND ASSESSMENT OF EFFECT OF FOOD AND ACID REDUCING AGENTS ON EXPOSURE
Anderson, K., Hsueh, C.H., Gurtovaya, O., Mathur, A., Taylor, J., Serone, A., Othman, A.A.
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The Relative Bioavailability and Effects of Food and Acid‐Reducing Agents on Filgotinib Tablets in Healthy Subjects
Anderson, Kacey, Zheng, Hao, Kotecha, Mona, Cuvin, Jennifer, Scott, Bob, Sharma, Shringi, Qin, Ann Ran‐Ran, Namour, Florence, Xin, Yan
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Pharmacokinetics of asciminib in the presence of CYP3A or P‐gp inhibitors, CYP3A inducers, and acid‐reducing agents
Hoch, Matthias, Huth, Felix, Sato, Masahiko, Sengupta, Tirtha, Quinlan, Michelle, Dodd, Stephanie, Kapoor, Shruti, Hourcade‐Potelleret, Florence
Published in Clinical and translational science (01.07.2022)
Published in Clinical and translational science (01.07.2022)
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Pharmacokinetics of the HIV integrase inhibitor S/GSK1349572 co-administered with acid-reducing agents and multivitamins in healthy volunteers
Patel, Parul, Song, Ivy, Borland, Julie, Patel, Apurva, Lou, Yu, Chen, Shuguang, Wajima, Toshihiro, Peppercorn, Amanda, Min, Sherene S., Piscitelli, Stephen C.
Published in Journal of antimicrobial chemotherapy (01.07.2011)
Published in Journal of antimicrobial chemotherapy (01.07.2011)
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Pharmacokinetics of once-daily boosted elvitegravir when administered in combination with acid-reducing agents
Ramanathan, Srinivasan, Mathias, Anita, Wei, Xuelian, Shen, Gong, Koziara, Joanna, Cheng, Andrew, Kearney, Brian P
Published in Journal of acquired immune deficiency syndromes (1999) (01.09.2013)
Published in Journal of acquired immune deficiency syndromes (1999) (01.09.2013)
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Effect of eliglustat on the pharmacokinetics of digoxin, metoprolol, and oral contraceptives and absorption of eliglustat when coadministered with acid-reducing agents
Thibault, Nathan, Ibrahim, Jennifer, Peterschmitt, M. Judith, Puga, Ana Cristina, Ross, Leorah, Vu, Lucie, Xue, Yong, Turpault, Sandrine
Published in Molecular genetics and metabolism (01.04.2020)
Published in Molecular genetics and metabolism (01.04.2020)
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Lack of effect of gastric acid-reducing agents on the pharmacokinetics of lopinavir/ritonavir in HIV-infected patients
Chiu, Yi-Lin, Klein, Cheri E, Woodward, William C, King, Kathryn R, Naylor, Christian, Awni, Walid, Brun, Scott
Published in AIDS patient care and STDs (01.04.2007)
Published in AIDS patient care and STDs (01.04.2007)
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PB2200: FOOD AND ACID REDUCING AGENT EFFECTS ON PHARMACOKINETICS (PK) AND PHARMACODYNAMICS (PD) OF THE COVALENT BRUTON TYROSINE KINASE INHIBITOR (BTKI) TL‐895 IN HEALTHY SUBJECTS
Allard, Martine, Krejsa, Cecile, Williams, Isaiah, Podoll, Terry, Steinmann, Kim, Slatter, Greg
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Effect of an Antacid (Aluminum Hydroxide/Magnesium Hydroxide/Simethicone) or a Proton Pump Inhibitor (Omeprazole) on the Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) in Healthy Adult Subjects
Patel, Gina, Gupta, Vipul K., Gasink, Leanne, Bajraktari, Floni, Lei, Yang, Jain, Akash, Srivastava, Praveen, Talley, Angela K.
Published in Antimicrobial agents and chemotherapy (18.04.2023)
Published in Antimicrobial agents and chemotherapy (18.04.2023)
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Model based assessment of food and acid reducing agent effects on oral absorption of mezigdomide (CC‐92480), a novel cereblon E3 ligase modulator
Wu, Fan, Liu, Liangang, Gaudy, Allison, Wang, Xiaomin, Carayannopoulos, Leon, Pourdehnad, Michael, Lamba, Manisha
Published in CPT: pharmacometrics and systems pharmacology (01.10.2023)
Published in CPT: pharmacometrics and systems pharmacology (01.10.2023)
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A physiologically based biopharmaceutics modeling (PBBM) framework for characterizing formulation-dependent food effects: Paving the road towards fed state virtual BE studies for itraconazole amorphous solid dispersions
Rudolph, Niklas, Charbe, Nitin, Plano, David, Shoyaib, Abdullah Al, Pal, Arindom, Boyce, Heather, Zhao, Liang, Wu, Fang, Polli, James, Dressman, Jennifer, Cristofoletti, Rodrigo
Published in European journal of pharmaceutical sciences (01.06.2025)
Published in European journal of pharmaceutical sciences (01.06.2025)
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The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756) − a selective CXCR2 antagonist − in healthy adult subjects
Miller, Bruce E., Mistry, Sunil, Smart, Kevin, Connolly, Paul, Carpenter, Donald C., Cooray, Hiran, Bloomer, Jackie C., Tal-Singer, Ruth, Lazaar, Aili L.
Published in BMC pharmacology & toxicology (20.06.2015)
Published in BMC pharmacology & toxicology (20.06.2015)
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Pharmacodynamic and Pharmacokinetic Drug Interactions between Fexuprazan, a Novel Potassium-Competitive Inhibitor, and Aspirin, in Healthy Subjects
Oh, JungJin, Yang, Eunsol, Jang, In-Jin, Lee, Hyejung, Yoo, Hokyun, Chung, Jae-Yong, Lee, SeungHwan, Oh, Jaeseong
Published in Pharmaceutics (01.02.2023)
Published in Pharmaceutics (01.02.2023)
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Proton-Pump Inhibitors and Fat Absorption in Cystic Fibrosis and Pancreatic Insufficiency: A Randomized Crossover Pilot Trial
Phillips, Anna Evans, Brownell, Jefferson N., Tindall, Alyssa, Kiernan, Bridget Dowd, Patel, Dhiren, Gelfond, Daniel, Stallings, Virginia A.
Published in Digestive diseases and sciences (01.03.2025)
Published in Digestive diseases and sciences (01.03.2025)
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