A YAP-centered mechanotransduction loop drives collective breast cancer cell invasion
Khalil, Antoine A., Smits, Daan, Haughton, Peter D., Koorman, Thijs, Jansen, Karin A., Verhagen, Mathijs P., van der Net, Mirjam, van Zwieten, Kitty, Enserink, Lotte, Jansen, Lisa, El-Gammal, Abdelrahman G., Visser, Daan, Pasolli, Milena, Tak, Max, Westland, Denise, van Diest, Paul J., Moelans, Cathy B., Roukens, M. Guy, Tavares, Sandra, Fortier, Anne-Marie, Park, Morag, Fodde, Riccardo, Gloerich, Martijn, Zwartkruis, Fried. J. T., Derksen, Patrick WB, de Rooij, Johan
Published in Nature communications (07.06.2024)
Published in Nature communications (07.06.2024)
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The long-term effect of mTOR inhibition on lipid and glucose metabolism in tuberous sclerosis complex: data from the Dutch TSC registry
Mulder, Femke V M, Peeters, Evelien F H I, Westerink, Jan, Zwartkruis, Fried J T, de Ranitz-Greven, Wendela L
Published in Orphanet journal of rare diseases (08.07.2022)
Published in Orphanet journal of rare diseases (08.07.2022)
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Evolution of the TOR Pathway
van Dam, Teunis J. P., Zwartkruis, Fried J. T., Bos, Johannes L., Snel, Berend
Published in Journal of molecular evolution (01.10.2011)
Published in Journal of molecular evolution (01.10.2011)
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Journal Article
Metabolic Alterations in NADSYN1-Deficient Cells
Meijer, Nils W F, Gerrits, Johan, Zwakenberg, Susan, Zwartkruis, Fried J T, Verhoeven-Duif, Nanda M, Jans, Judith J M
Published in Metabolites (01.12.2023)
Published in Metabolites (01.12.2023)
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Direct Infusion Mass Spectrometry to Rapidly Map Metabolic Flux of Substrates Labeled with Stable Isotopes
Meijer, Nils W F, Zwakenberg, Susan, Gerrits, Johan, Westland, Denise, Ardisasmita, Arif I, Fuchs, Sabine A, Verhoeven-Duif, Nanda M, Jans, Judith J M, Zwartkruis, Fried J T
Published in Metabolites (01.05.2024)
Published in Metabolites (01.05.2024)
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Upregulation of the pathogenic transcription factor SPI1/PU.1 in tuberous sclerosis complex and focal cortical dysplasia by oxidative stress
Zimmer, Till S., Korotkov, Anatoly, Zwakenberg, Susan, Jansen, Floor E., Zwartkruis, Fried J. T., Rensing, Nicholas R., Wong, Michael, Mühlebner, Angelika, Vliet, Erwin A., Aronica, Eleonora, Mills, James D.
Published in Brain pathology (Zurich, Switzerland) (01.09.2021)
Published in Brain pathology (Zurich, Switzerland) (01.09.2021)
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Amino Acids Mediate mTOR/Raptor Signaling through Activation of Class 3 Phosphatidylinositol 3OH-Kinase
Nobukuni, Takahiro, Joaquin, Manel, Roccio, Marta, Dann, Stephen G., Kim, So Young, Gulati, Pawan, Byfield, Maya P., Backer, Jonathan M., Natt, Francois, Bos, Johannes L., Fried J. T. Zwartkruis, Thomas, George, Schlessinger, Joseph
Published in Proceedings of the National Academy of Sciences - PNAS (04.10.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (04.10.2005)
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Identification of a Loss-of-Function Mutation in the Context of Glutaminase Deficiency and Neonatal Epileptic Encephalopathy
Rumping, Lynne, Büttner, Benjamin, Maier, Oliver, Rehmann, Holger, Lequin, Maarten, Schlump, Jan-Ulrich, Schmitt, Bernhard, Schiebergen-Bronkhorst, Birgit, Prinsen, Hubertus C M T, Losa, Michele, Fingerhut, Ralph, Lemke, Johannes R, Zwartkruis, Fried J T, Houwen, Roderick H J, Jans, Judith J M, Verhoeven-Duif, Nanda M, van Hasselt, Peter M, Jamra, Rami
Published in Archives of neurology (Chicago) (01.03.2019)
Published in Archives of neurology (Chicago) (01.03.2019)
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CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation
De Rubeis, Silvia, Pasciuto, Emanuela, Li, Ka Wan, Fernández, Esperanza, Di Marino, Daniele, Buzzi, Andrea, Ostroff, Linnaea E., Klann, Eric, Zwartkruis, Fried J.T., Komiyama, Noboru H., Grant, Seth G.N., Poujol, Christel, Choquet, Daniel, Achsel, Tilmann, Posthuma, Danielle, Smit, August B., Bagni, Claudia
Published in Neuron (Cambridge, Mass.) (18.09.2013)
Published in Neuron (Cambridge, Mass.) (18.09.2013)
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Retrotransposition and mutation events yield Rap1 GTPases with differential signalling capacity
Zemojtel, Tomasz, Duchniewicz, Marlena, Zhang, Zhongchun, Paluch, Taisa, Luz, Hannes, Penzkofer, Tobias, Scheele, Jürgen S, Zwartkruis, Fried J T
Published in BMC evolutionary biology (19.02.2010)
Published in BMC evolutionary biology (19.02.2010)
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Rap1 Signaling Is Required for Suppression of Ras-Generated Reactive Oxygen Species and Protection Against Oxidative Stress in T Lymphocytes
Remans, Philip H. J, Gringhuis, Sonja I, van Laar, Jacob M, Sanders, Marjolein E, Papendrecht-van der Voort, Ellen A. M, Zwartkruis, Fried J. T, Levarht, E. W. Nivine, Rosas, Marcela, Coffer, Paul J, Breedveld, Ferdinand C, Bos, Johannes L, Tak, Paul P, Verweij, Cornelis L, Reedquist, Kris A
Published in The Journal of immunology (1950) (15.07.2004)
Published in The Journal of immunology (1950) (15.07.2004)
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Mammalian target of rapamycin complex I (mTORC1) activity in ras homologue enriched in brain (Rheb)-deficient mouse embryonic fibroblasts
Groenewoud, Marlous J, Goorden, Susan M I, Kassies, Jorien, Pellis-van Berkel, Wendy, Lamb, Richard F, Elgersma, Ype, Zwartkruis, Fried J T
Published in PloS one (26.11.2013)
Published in PloS one (26.11.2013)
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Activation of FoxO transcription factors contributes to the antiproliferative effect of cAMP
BEA KUIPERIJ, H, VAN DER HORST, Armando, RAAIJMAKERS, Judith, WEIJZEN, Sanne, MEDEMA, Rene H, BOS, Johannes L, BURGERING, Boudewijn M. T, ZWARTKRUIS, Fried J. T
Published in Oncogene (17.03.2005)
Published in Oncogene (17.03.2005)
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RAP-1 and the RAL-1/exocyst pathway coordinate hypodermal cell organization in Caenorhabditis elegans
Frische, Ester W, Pellis-van Berkel, Wendy, van Haaften, Gijs, Cuppen, Edwin, Plasterk, Ronald HA, Tijsterman, Marcel, Bos, Johannes L, Zwartkruis, Fried J T
Published in The EMBO journal (12.12.2007)
Published in The EMBO journal (12.12.2007)
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Journal Article
Rheb and Rags come together at the lysosome to activate mTORC1
Groenewoud, Marlous J, Zwartkruis, Fried J T
Published in Biochemical Society transactions (01.08.2013)
Published in Biochemical Society transactions (01.08.2013)
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