Metabolomic and Genome-wide Association Studies Reveal Potential Endogenous Biomarkers for OATP1B1
Yee, S W, Giacomini, M M, Hsueh, C-H, Weitz, D, Liang, X, Goswami, S, Kinchen, J M, Coelho, A, Zur, A A, Mertsch, K, Brian, W, Kroetz, D L, Giacomini, K M
Published in Clinical pharmacology and therapeutics (01.11.2016)
Published in Clinical pharmacology and therapeutics (01.11.2016)
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Journal Article
Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1-Transfected Human Embryonic Kidney 293 Cells
Chien, Huan-Chieh, Zur, Arik A, Maurer, Tristan S, Yee, Sook Wah, Tolsma, John, Jasper, Paul, Scott, Dennis O, Giacomini, Kathleen M
Published in Drug metabolism and disposition (01.03.2016)
Published in Drug metabolism and disposition (01.03.2016)
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Journal Article
Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug-Drug Interaction Evaluation: Perspectives From the International Transporter Consortium
Chu, Xiaoyan, Liao, Mingxiang, Shen, Hong, Yoshida, Kenta, Zur, Arik A, Arya, Vikram, Galetin, Aleksandra, Giacomini, Kathleen M, Hanna, Imad, Kusuhara, Hiroyuki, Lai, Yurong, Rodrigues, David, Sugiyama, Yuichi, Zamek-Gliszczynski, Maciej J, Zhang, Lei
Published in Clinical pharmacology and therapeutics (01.11.2018)
Published in Clinical pharmacology and therapeutics (01.11.2018)
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Journal Article
Drug Metabolites Potently Inhibit Renal Organic Anion Transporters, OAT1 and OAT3
Zou, Ling, Matsson, Pär, Stecula, Adrian, Ngo, Huy X., Zur, Arik A., Giacomini, Kathleen M.
Published in Journal of pharmaceutical sciences (01.01.2021)
Published in Journal of pharmaceutical sciences (01.01.2021)
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Journal Article
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin
Chen, Ligong, Shu, Yan, Liang, Xiaomin, Chen, Eugene C., Yee, Sook Wah, Zur, Arik A., Li, Shuanglian, Xu, Lu, Keshari, Kayvan R., Lin, Michael J., Chien, Huan-Chieh, Zhang, Youcai, Morrissey, Kari M., Liu, Jason, Ostrem, Jonathan, Younger, Noah S., Kurhanewicz, John, Shokat, Keven M., Ashrafi, Kaveh, Giacomini, Kathleen M.
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2014)
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Methylation of L1RE1, RARB, and RASSF1 function as possible biomarkers for the differential diagnosis of lung cancer
Walter, R F H, Rozynek, P, Casjens, S, Werner, R, Mairinger, F D, Speel, E J M, Zur Hausen, A, Meier, S, Wohlschlaeger, J, Theegarten, D, Behrens, T, Schmid, K W, Brüning, T, Johnen, G
Published in PloS one (31.05.2018)
Published in PloS one (31.05.2018)
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Journal Article
Discovery of Potent, Selective Multidrug and Toxin Extrusion Transporter 1 (MATE1, SLC47A1) Inhibitors Through Prescription Drug Profiling and Computational Modeling
Wittwer, Matthias B, Zur, Arik A, Khuri, Natalia, Kido, Yasuto, Kosaka, Alan, Zhang, Xuexiang, Morrissey, Kari M, Sali, Andrej, Huang, Yong, Giacomini, Kathleen M
Published in Journal of medicinal chemistry (14.02.2013)
Published in Journal of medicinal chemistry (14.02.2013)
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Journal Article
Reevaluating the Substrate Specificity of the L‑Type Amino Acid Transporter (LAT1)
Chien, Huan-Chieh, Colas, Claire, Finke, Karissa, Springer, Seth, Stoner, Laura, Zur, Arik A., Venteicher, Brooklynn, Campbell, Jerome, Hall, Colton, Flint, Andrew, Augustyn, Evan, Hernandez, Christopher, Heeren, Nathan, Hansen, Logan, Anthony, Abby, Bauer, Justine, Fotiadis, Dimitrios, Schlessinger, Avner, Giacomini, Kathleen M., Thomas, Allen A.
Published in Journal of medicinal chemistry (23.08.2018)
Published in Journal of medicinal chemistry (23.08.2018)
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Journal Article
Efficacy of three different cervical dislocation methods for on-farm killing of layer chicks
Bandara, R.M.A.S., Torrey, S., Turner, P.V., zur Linden, A., Schwean-Lardner, K., Widowski, T.M.
Published in Poultry science (01.04.2023)
Published in Poultry science (01.04.2023)
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Journal Article
Reviewing the current evidence supporting early B-cells as the cellular origin of Merkel Cell Carcinoma
Sauer, C.M, Haugg, A.M, Chteinberg, E, Rennspiess, D, Winnepenninckx, V, Speel, E.-J, Becker, J.C, Kurz, A.K, zur Hausen, A
Published in Critical reviews in oncology/hematology (01.08.2017)
Published in Critical reviews in oncology/hematology (01.08.2017)
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Journal Article
The Effect of Famotidine, a MATE1-Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin
Hibma, Jennifer E., Zur, Arik A., Castro, Richard A., Wittwer, Matthias B., Keizer, Ron J., Yee, Sook Wah, Goswami, Srijib, Stocker, Sophie L., Zhang, Xuexiang, Huang, Yong, Brett, Claire M., Savic, Radojka M., Giacomini, Kathleen M.
Published in Clinical pharmacokinetics (01.06.2016)
Published in Clinical pharmacokinetics (01.06.2016)
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Journal Article
LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates
Zur, Arik A., Chien, Huan-Chieh, Augustyn, Evan, Flint, Andrew, Heeren, Nathan, Finke, Karissa, Hernandez, Christopher, Hansen, Logan, Miller, Sydney, Lin, Lawrence, Giacomini, Kathleen M., Colas, Claire, Schlessinger, Avner, Thomas, Allen A.
Published in Bioorganic & medicinal chemistry letters (15.10.2016)
Published in Bioorganic & medicinal chemistry letters (15.10.2016)
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Journal Article
Comparison of laparoscopic and mini incision open donor nephrectomy: single blind, randomised controlled clinical trial
Kok, Niels F M, Lind, May Y, Hansson, Birgitta M E, Pilzecker, Desiree, Mertens zur Borg, Ingrid R A M, Knipscheer, Ben C, Hazebroek, Eric J, Dooper, Ine M, Weimar, Willem, Hop, Wim C J, Adang, Eddy M M, van der Wilt, Gert Jan, Bonjer, Hendrik J, van der Vliet, Jordanus A, IJzermans, Jan N M
Published in BMJ (29.07.2006)
Published in BMJ (29.07.2006)
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AGI-134: a fully synthetic α-Gal glycolipid that converts tumors into in situ autologous vaccines, induces anti-tumor immunity and is synergistic with an anti-PD-1 antibody in mouse melanoma models
Shaw, Stephen M, Middleton, Jenny, Wigglesworth, Kim, Charlemagne, Amber, Schulz, Oliver, Glossop, Melanie S, Whalen, Giles F, Old, Robert, Westby, Mike, Pickford, Chris, Tabakman, Rinat, Carmi-Levy, Irit, Vainstein, Abi, Sorani, Ella, Zur, Arik A, Kristian, Sascha A
Published in Cancer cell international (19.12.2019)
Published in Cancer cell international (19.12.2019)
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