Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos
Wei, Yinghui, Li, Zhifang, Xu, Kui, Feng, Hu, Xie, Long, Li, Di, Zuo, Zhenrui, Zhang, Meiling, Xu, Chunlong, Yang, Hui, Zuo, Erwei
Published in Cell discovery (18.03.2022)
Published in Cell discovery (18.03.2022)
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Cytosine base editors induce off-target mutations and adverse phenotypic effects in transgenic mice
Yan, Nana, Feng, Hu, Sun, Yongsen, Xin, Ying, Zhang, Haihang, Lu, Hongjiang, Zheng, Jitan, He, Chenfei, Zuo, Zhenrui, Yuan, Tanglong, Li, Nana, Xie, Long, Wei, Wu, Sun, Yidi, Zuo, Erwei
Published in Nature communications (30.03.2023)
Published in Nature communications (30.03.2023)
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Undetectable off-target effects induced by FokI catalytic domain in mouse embryos
Xie, Long, Feng, Hu, Li, Zhifang, Li, Di, Yang, Xiali, Yuan, Tanglong, Yan, Nana, He, Chenfei, Zheng, Jitan, Zuo, Zhenrui, Zheng, Yaxuan, Cao, Yaqi, Lu, Yangqing, Xiong, Xing Yao, Zuo, Erwei
Published in Genome Biology (20.02.2024)
Published in Genome Biology (20.02.2024)
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Human cleaving embryos enable efficient mitochondrial base-editing with DdCBE
Wei, Yinghui, Xu, Chunlong, Feng, Hu, Xu, Kui, Li, Zhifang, Hu, Jing, Zhou, Ling, Wei, Yu, Zuo, Zhenrui, Zuo, Erwei, Li, Wen, Yang, Hui, Zhang, Meiling
Published in Cell discovery (01.02.2022)
Published in Cell discovery (01.02.2022)
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FokI-RYdCas9 Mediates Nearly PAM-Less and High-Precise Gene Editing in Human Cells
Li, Di, Cao, Yaqi, Xie, Long, He, Chenfei, Jiao, Danrong, Ma, Mengxue, Zuo, Zhenrui, Zuo, Erwei, Yang, Xiaogan
Published in Current Issues in Molecular Biology (01.05.2024)
Published in Current Issues in Molecular Biology (01.05.2024)
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Deep learning models incorporating endogenous factors beyond DNA sequences improve the prediction accuracy of base editing outcomes
Yuan, Tanglong, Wu, Leilei, Li, Shiyan, Zheng, Jitan, Li, Nana, Xiao, Xiao, Zhang, Haihang, Fei, Tianyi, Xie, Long, Zuo, Zhenrui, Li, Di, Huang, Pinzheng, Feng, Hu, Cao, Yaqi, Yan, Nana, Wei, Xinming, Shi, Lei, Sun, Yongsen, Wei, Wu, Sun, Yidi, Zuo, Erwei
Published in Cell discovery (20.02.2024)
Published in Cell discovery (20.02.2024)
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Reducing off-target effects of DdCBEs by reversing amino acid charge near DNA interaction sites
Xie, Long, Cao, Yaqi, Li, Di, Ma, Mengxue, Jiao, Danrong, Feng, Hu, Zuo, Zhenrui, Zuo, Erwei
Published in Cell research (10.09.2024)
Published in Cell research (10.09.2024)
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Structure-guided discovery of highly efficient cytidine deaminases with sequence-context independence
Xu, Kui, Feng, Hu, Zhang, Haihang, He, Chenfei, Kang, Huifang, Yuan, Tanglong, Shi, Lei, Zhou, Chikai, Hua, Guoying, Cao, Yaqi, Zuo, Zhenrui, Zuo, Erwei
Published in Nature biomedical engineering (03.06.2024)
Published in Nature biomedical engineering (03.06.2024)
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