Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer
Queiroz, Andre Lima, Dantas, Ezequiel, Ramsamooj, Shakti, Murthy, Anirudh, Ahmed, Mujmmail, Zunica, Elizabeth R M, Liang, Roger J, Murphy, Jessica, Holman, Corey D, Bare, Curtis J, Ghahramani, Gregory, Wu, Zhidan, Cohen, David E, Kirwan, John P, Cantley, Lewis C, Axelrod, Christopher L, Goncalves, Marcus D
Published in Nature communications (08.08.2022)
Published in Nature communications (08.08.2022)
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Journal Article
Bariatric surgery alters mitochondrial function in gut mucosa
Ross, Robert C., Heintz, Elizabeth C., Zunica, Elizabeth R. M., Townsend, R. Leigh, Spence, Amanda E., Schauer, Philip R., Kirwan, John P., Axelrod, Christopher L., Albaugh, Vance L.
Published in Surgical endoscopy (01.11.2023)
Published in Surgical endoscopy (01.11.2023)
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Journal Article
Obesity Management in the Primary Prevention of Hepatocellular Carcinoma
Zunica, Elizabeth R M, Heintz, Elizabeth C, Axelrod, Christopher L, Kirwan, John P
Published in Cancers (01.08.2022)
Published in Cancers (01.08.2022)
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Journal Article
GDF15 Mediates the Effect of Skeletal Muscle Contraction on Glucose-Stimulated Insulin Secretion
Zhang, Hui, Mulya, Anny, Nieuwoudt, Stephan, Vandanmagsar, Bolormaa, McDowell, Ruth, Heintz, Elizabeth C, Zunica, Elizabeth R M, Collier, J Jason, Bozadjieva-Kramer, Nadejda, Seeley, Randy J, Axelrod, Christopher L, Kirwan, John P
Published in Diabetes (New York, N.Y.) (01.08.2023)
Published in Diabetes (New York, N.Y.) (01.08.2023)
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Journal Article
Effects of metformin on glucose metabolism and mitochondrial function in patients with obstructive sleep apnea: A pilot randomized trial
Zunica, Elizabeth R. M., Heintz, Elizabeth C., Dantas, Wagner S., Hebert, R. Caitlin, Tanksley, MaKayla, Beyl, Robbie A., Mader, Edward C., Kirwan, John P., Axelrod, Christopher L., Singh, Prachi
Published in Physiological reports (01.02.2024)
Published in Physiological reports (01.02.2024)
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Journal Article
Moringa Oleifera Seed Extract Concomitantly Supplemented with Chemotherapy Worsens Tumor Progression in Mice with Triple Negative Breast Cancer and Obesity
Zunica, Elizabeth R. M., Yang, Shengping, Coulter, Ann, White, Christy, Kirwan, John P., Gilmore, Linda A.
Published in Nutrients (24.08.2021)
Published in Nutrients (24.08.2021)
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Journal Article
Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15
Zunica, Elizabeth R. M., Axelrod, Christopher L., Cho, Eunhan, Spielmann, Guillaume, Davuluri, Gangarao, Alexopoulos, Stephanie J., Beretta, Martina, Hoehn, Kyle L., Dantas, Wagner S., Stadler, Krisztian, King, William T., Pergola, Kathryn, Irving, Brian A., Langohr, Ingeborg M., Yang, Shengping, Hoppel, Charles L., Gilmore, L. Anne, Kirwan, John P.
Published in Cancer & metabolism (09.10.2021)
Published in Cancer & metabolism (09.10.2021)
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Journal Article
CRISPR/Cas9-engineered Drosophila knock-in models to study VCP diseases
Wall, Jordan M, Basu, Ankita, Zunica, Elizabeth R M, Dubuisson, Olga S, Pergola, Kathryn, Broussard, Joshua P, Kirwan, John P, Axelrod, Christopher L, Johnson, Alyssa E
Published in Disease models & mechanisms (01.07.2021)
Published in Disease models & mechanisms (01.07.2021)
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Journal Article
BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control
Axelrod, Christopher L, King, William T, Davuluri, Gangarao, Noland, Robert C, Hall, Jacob, Hull, Michaela, Dantas, Wagner S, Zunica, Elizabeth RM, Alexopoulos, Stephanie J, Hoehn, Kyle L, Langohr, Ingeborg, Stadler, Krisztian, Doyle, Haylee, Schmidt, Eva, Nieuwoudt, Stephan, Fitzgerald, Kelly, Pergola, Kathryn, Fujioka, Hisashi, Mey, Jacob T, Fealy, Ciaran, Mulya, Anny, Beyl, Robbie, Hoppel, Charles L, Kirwan, John P
Published in EMBO molecular medicine (07.07.2020)
Published in EMBO molecular medicine (07.07.2020)
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Journal Article
Weight‐independent effects of Roux‐en‐Y gastric bypass surgery on remission of nonalcoholic fatty liver disease in mice
Axelrod, Christopher L., Langohr, Ingeborg, Dantas, Wagner S., Heintz, Elizabeth C., Vandanmagsar, Bolormaa, Yang, Shengping, Zunica, Elizabeth R. M., Townsend, R. Leigh, Albaugh, Vance L., Berthoud, Hans‐Rudolf, Kirwan, John P.
Published in Obesity (Silver Spring, Md.) (01.12.2023)
Published in Obesity (Silver Spring, Md.) (01.12.2023)
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Journal Article
Mitochondrial Uncoupling Decreases Sarcopenic Obesity By Activation of Skeletal Muscle Mitochondrial Quality Control and Attenuated ER Stress
Dantas, Wagner S, Zunica, Elizabeth R M, Heintz, Elizabeth C, Hoppel, Charles L, Axelrod, Christopher L, Kirwan, John P
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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Journal Article
Restricting bioenergetic efficiency enhances longevity and mitochondrial redox capacity in Drosophila melanogaster
Taylor, Analisa L., Dubuisson, Olga, Pandey, Pritika, Zunica, Elizabeth R. M., Vandanmagsar, Bolormaa, Dantas, Wagner S., Johnson, Alyssa, Axelrod, Christopher L., Kirwan, John P.
Published in Aging cell (01.05.2024)
Published in Aging cell (01.05.2024)
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Journal Article
Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics
King, William T., Axelrod, Christopher L., Zunica, Elizabeth R.M., Noland, Robert C., Davuluri, Gangarao, Fujioka, Hisashi, Tandler, Bernard, Pergola, Kathryn, Hermann, Gerlinda E., Rogers, Richard C., López-Domènech, Sandra, Dantas, Wagner S., Stadler, Krisztian, Hoppel, Charles L., Kirwan, John P.
Published in The Journal of biological chemistry (01.10.2021)
Published in The Journal of biological chemistry (01.10.2021)
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Journal Article
Mitochondrial uncoupling attenuates sarcopenic obesity by enhancing skeletal muscle mitophagy and quality control
Dantas, Wagner S., Zunica, Elizabeth R.M., Heintz, Elizabeth C., Vandanmagsar, Bolormaa, Floyd, Z. Elizabeth, Yu, Yongmei, Fujioka, Hisashi, Hoppel, Charles L., Belmont, Kathryn P., Axelrod, Christopher L., Kirwan, John P.
Published in Journal of cachexia, sarcopenia and muscle (01.06.2022)
Published in Journal of cachexia, sarcopenia and muscle (01.06.2022)
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Journal Article
The bioenergetic landscape of cancer
Zunica, Elizabeth R.M., Axelrod, Christopher L., Gilmore, L. Anne, Gnaiger, Erich, Kirwan, John P.
Published in Molecular metabolism (Germany) (01.08.2024)
Published in Molecular metabolism (Germany) (01.08.2024)
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Journal Article
Abstract 2145: Untargeted sequencing of human breast cancer reveals induction of pro-apoptotic and anti-proliferative transcriptional signatures in response to mitochondrial uncoupling
Zunica, Elizabeth R., Axelrod, Christopher L., Cho, Eunhan, Spielmann, Guillaume, Yang, Shengping, Gilmore, L Anne, Kirwan, John P.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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