GD2 targeting by dinutuximab beta is a promising immunotherapeutic approach against malignant glioma
Marx, Sascha, Wilken, Fabian, Wagner, Isabel, Marx, Madlen, Troschke-Meurer, Sascha, Zumpe, Maxi, Bien-Moeller, Sandra, Weidemeier, Martin, Baldauf, Joerg, Fleck, Steffen K., Rauch, Bernhard H., Schroeder, Henry W. S., Lode, Holger, Siebert, Nikolai
Published in Journal of neuro-oncology (01.05.2020)
Published in Journal of neuro-oncology (01.05.2020)
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Journal Article
PD-1 blockade augments anti-neuroblastoma immune response induced by anti-GD2 antibody ch14.18/CHO
Siebert, Nikolai, Zumpe, Maxi, Jüttner, Madlen, Troschke-Meurer, Sascha, Lode, Holger N.
Published in Oncoimmunology (03.10.2017)
Published in Oncoimmunology (03.10.2017)
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Journal Article
Detection of rat hepatitis E virus in wild Norway rats (Rattus norvegicus) and Black rats (Rattus rattus) from 11 European countries
Ryll, René, Bernstein, Samuel, Heuser, Elisa, Schlegel, Mathias, Dremsek, Paul, Zumpe, Maxi, Wolf, Sandro, Pépin, Michel, Bajomi, Daniel, Müller, Gabi, Heiberg, Ann-Charlotte, Spahr, Carina, Lang, Johannes, Groschup, Martin H., Ansorge, Hermann, Freise, Jona, Guenther, Sebastian, Baert, Kristof, Ruiz-Fons, Francisco, Pikula, Jiri, Knap, Nataša, Tsakmakidis, Ιoannis, Dovas, Chrysostomos, Zanet, Stefania, Imholt, Christian, Heckel, Gerald, Johne, Reimar, Ulrich, Rainer G.
Published in Veterinary microbiology (01.09.2017)
Published in Veterinary microbiology (01.09.2017)
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Journal Article
Immunomonitoring of Stage IV Relapsed Neuroblastoma Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplantation and Subsequent GD2 (ch14.18/CHO) Antibody Treatment
Seitz, Christian Martin, Flaadt, Tim, Mezger, Markus, Lang, Anne-Marie, Michaelis, Sebastian, Katz, Marie, Syring, Desireé, Joechner, Alexander, Rabsteyn, Armin, Siebert, Nikolai, Troschke-Meurer, Sascha, Zumpe, Maxi, Lode, Holger N., Yang, Sile F., Atar, Daniel, Mast, Anna-Sophia, Scheuermann, Sophia, Heubach, Florian, Handgretinger, Rupert, Lang, Peter, Schlegel, Patrick
Published in Frontiers in immunology (22.07.2021)
Published in Frontiers in immunology (22.07.2021)
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Journal Article
Low CD4⁺/CD25⁺/CD127⁻ regulatory T cell- and high INF-γ levels are associated with improved survival of neuroblastoma patients treated with long-term infusion of ch14.18/CHO combined with interleukin-2
Troschke-Meurer, Sascha, Siebert, Nikolai, Marx, Madlen, Zumpe, Maxi, Ehlert, Karoline, Mutschlechner, Oliver, Loibner, Hans, Ladenstein, Ruth, Lode, Holger N.
Published in Oncoimmunology (02.12.2019)
Published in Oncoimmunology (02.12.2019)
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Journal Article
Reduction of CD11b+ myeloid suppressive cells augments anti-neuroblastoma immune response induced by the anti-GD2 antibody ch14.18/CHO
Siebert, Nikolai, Zumpe, Maxi, von Lojewski, Leon, Troschke-Meurer, Sascha, Marx, Madlen, Lode, Holger N.
Published in Oncoimmunology (01.01.2020)
Published in Oncoimmunology (01.01.2020)
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Journal Article
BCL11B depletion induces the development of highly cytotoxic innate T cells out of IL-15 stimulated peripheral blood αβ CD8+ T cells
Forkel, Hannes, Grabarczyk, Piotr, Depke, Maren, Troschke-Meurer, Sascha, Simm, Stefan, Hammer, Elke, Michalik, Stephan, Hentschker, Christian, Corleis, Björn, Loyal, Lucie, Zumpe, Maxi, Siebert, Nikolai, Dorhoi, Anca, Thiel, Andreas, Lode, Holger, Völker, Uwe, Schmidt, Christian A.
Published in Oncoimmunology (2022)
Published in Oncoimmunology (2022)
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Journal Article
Generation and Characterization of a Human/Mouse Chimeric GD2-Mimicking Anti-Idiotype Antibody Ganglidiximab for Active Immunotherapy against Neuroblastoma
Eger, Christin, Siebert, Nikolai, Seidel, Diana, Zumpe, Maxi, Jüttner, Madlen, Brandt, Sven, Müller, Hans-Peter, Lode, Holger N
Published in PloS one (01.03.2016)
Published in PloS one (01.03.2016)
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Journal Article
Impact of IL-2 on Treatment Tolerance in Patients With High-Risk Neuroblastoma Treated With Dinutuximab Beta-Based Immunotherapy
Cicek, Filiz, Troschke-Meurer, Sascha, Ceylan, Kiraz, Jahns, Luciana J, Zumpe, Maxi, Siebert, Nikolai, Ehlert, Karoline, Lode, Holger N
Published in Frontiers in pediatrics (16.12.2020)
Published in Frontiers in pediatrics (16.12.2020)
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Journal Article
Single-agent activity of the anti-GD2 antibody dinutuximab beta given as a long-term infusion in relapsed and refractory neuroblastoma (APN311-304)
Lode, Holger N., Ehlert, Karoline, Huber, Stephanie, Siebert, Nikolai, Troschke-Meurer, Sascha, Zumpe, Maxi, Loibner, Hans, Ladenstein, Ruth Lydia
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
Long-term, continuous infusion of single-agent dinutuximab beta for relapsed/refractory neuroblastoma: an open-label, single-arm, Phase 2 study
Lode, Holger N., Ehlert, Karoline, Huber, Stephanie, Troschke-Meurer, Sascha, Siebert, Nikolai, Zumpe, Maxi, Loibner, Hans, Ladenstein, Ruth
Published in British journal of cancer (23.11.2023)
Published in British journal of cancer (23.11.2023)
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Journal Article
The Immunocytokine FAP-IL-2v Enhances Anti-Neuroblastoma Efficacy of the Anti-GD[sub.2] Antibody Dinutuximab Beta
Siebert, Nikolai, Leopold, Justus, Zumpe, Maxi, Troschke-Meurer, Sascha, Biskupski, Simon, Zikoridse, Alexander, Lode, Holger N
Published in Cancers (01.10.2022)
Published in Cancers (01.10.2022)
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Journal Article
Combined Blockade of TIGIT and PD-L1 Enhances Anti-Neuroblastoma Efficacy of GD2-Directed Immunotherapy with Dinutuximab Beta
Siebert, Nikolai, Zumpe, Maxi, Schwencke, Christian Heinrich, Biskupski, Simon, Troschke-Meurer, Sascha, Leopold, Justus, Zikoridse, Alexander, Lode, Holger N
Published in Cancers (23.06.2023)
Published in Cancers (23.06.2023)
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Journal Article
The Immunocytokine FAP-IL-2v Enhances Anti-Neuroblastoma Efficacy of the Anti-GD2 Antibody Dinutuximab Beta
Siebert, Nikolai, Leopold, Justus, Zumpe, Maxi, Troschke-Meurer, Sascha, Biskupski, Simon, Zikoridse, Alexander, Lode, Holger N.
Published in Cancers (04.10.2022)
Published in Cancers (04.10.2022)
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Journal Article
Immune Response and Outcome of High-Risk Neuroblastoma Patients Immunized with Anti-Idiotypic Antibody Ganglidiomab: Results from Compassionate-Use Treatments
Klingel, Leah, Siebert, Nikolai, Troschke-Meurer, Sascha, Zumpe, Maxi, Ehlert, Karoline, Huber, Stefanie, Loibner, Hans, Mutschlechner, Oliver, Lode, Holger N
Published in Cancers (25.11.2022)
Published in Cancers (25.11.2022)
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Journal Article
Association of regulatory- and helper-T- cells with inferior survival of neuroblastoma patients treated with long-term infusion of ch14.18/CHO combined with interleukin-2
Lode, Holger N., Troschke-Meurer, Sascha, Marx, Madlen, Zumpe, Maxi, Ehlert, Karoline, Loibner, Hans, Ladenstein, Ruth Lydia, Siebert, Nikolai
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
Neuroblastoma patients with high-affinity FCGR2A, -3A and stimulatory KIR 2DS2 treated by long-term infusion of anti-GD2 antibody ch14.18/CHO show higher ADCC levels and improved event-free survival
Siebert, Nikolai, Jensen, Christian, Troschke-Meurer, Sascha, Zumpe, Maxi, Jüttner, Madlen, Ehlert, Karoline, Kietz, Silke, Müller, Ina, Lode, Holger N.
Published in Oncoimmunology (01.11.2016)
Published in Oncoimmunology (01.11.2016)
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