Inhibition of RAS: proven and potential vulnerabilities
Zuberi, Mariyam, Khan, Imran, O'Bryan, John P
Published in Biochemical Society transactions (30.10.2020)
Published in Biochemical Society transactions (30.10.2020)
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Journal Article
Utility of Serum miR-125b as a Diagnostic and Prognostic Indicator and Its Alliance with a Panel of Tumor Suppressor Genes in Epithelial Ovarian Cancer
Zuberi, Mariyam, Khan, Imran, Mir, Rashid, Gandhi, Gauri, Ray, Prakash Chandra, Saxena, Alpana
Published in PloS one (19.04.2016)
Published in PloS one (19.04.2016)
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Journal Article
Ectopic PD-L1 expression in JAK2 (V617F) myeloproliferative neoplasm patients is mediated via increased activation of STAT3 and STAT5
Guru, Sameer Ahamd, Sumi, Mamta P., Mir, Rashid, Waza, Ajaz Ahmad, Bhat, Musadiq Ahmad, Zuberi, Mariyam, Lali, Promod, Saxena, Alpana
Published in Human cell : official journal of Human Cell Research Society (01.10.2020)
Published in Human cell : official journal of Human Cell Research Society (01.10.2020)
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Journal Article
Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants
Khan, Imran, Koide, Akiko, Zuberi, Mariyam, Ketavarapu, Gayatri, Denbaum, Eric, Teng, Kai Wen, Rhett, J. Matthew, Spencer-Smith, Russell, Hobbs, G. Aaron, Camp, Ernest Ramsay, Koide, Shohei, O'Bryan, John P.
Published in Cell reports (Cambridge) (08.02.2022)
Published in Cell reports (Cambridge) (08.02.2022)
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Journal Article
Epigenetic Silencing of DAPK1and p16INK4a Genes by CpG Island Hypermethylation in Epithelial Ovarian Cancer Patients
Zuberi, Mariyam, Dholariya, Sagar, Khan, Imran, Mir, Rashid, Guru, Sameer, bhat, Musadiq, Sumi, Mamta, Saxena, Alpana
Published in Indian journal of clinical biochemistry (01.04.2021)
Published in Indian journal of clinical biochemistry (01.04.2021)
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Journal Article
PDGFRα promoter polymorphisms and expression patterns influence risk of development of imatinib-induced thrombocytopenia in chronic myeloid leukemia: A study from India
Guru, Sameer Ahmad, Mir, Rashid, Bhat, Musadiq, Najar, Imtiyaz, Zuberi, Mariyam, Sumi, Mamta, Masroor, Mirza, Gupta, Naresh, Saxena, Alpana
Published in Tumor biology (01.10.2017)
Published in Tumor biology (01.10.2017)
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Journal Article
Correction to: Ectopic PD-L1 expression in JAK2 (V617F) myeloproliferative neoplasm patients is mediated via increased activation of STAT3 and STAT5
Guru, Sameer Ahamd, Sumi, Mamta P., Mir, Rashid, Waza, Ajaz Ahmad, Bhat, Musadiq Ahmad, Zuberi, Mariyam, Lali, Promod, Saxena, Alpana
Published in Human cell : official journal of Human Cell Research Society (01.10.2020)
Published in Human cell : official journal of Human Cell Research Society (01.10.2020)
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Journal Article
Clinical implications of cytosine deletion of exon 5 of P53 gene in non small cell lung cancer patients
Mir, Rashid, Masroor, Mirza, Javid, Jamsheed, Ahamad, Imtiyaz, Farooq, Shazia, Yadav, Prasant, Zuberi, Mariyam, Lone, Maqbool, Ray, P.C, Saxena, Alpana
Published in South Asian Journal of Cancer (01.01.2016)
Published in South Asian Journal of Cancer (01.01.2016)
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Journal Article
The C609T (Pro187Ser) Null Polymorphism of the NQO1 Gene Contributes Significantly to Breast Cancer Susceptibility in North Indian Populations: a Case Control Study
Yadav, Prasant, Mir, Rashid, Nandi, Kajal, Javid, Jamsheed, Masroor, Mirza, Ahmad, Imtiyaz, Zuberi, Mariyam, Kaza, RCM, Jain, SK, Khurana, Nita, Ray, Prakash Chandra, Saxena, Alpana
Published in Asian Pacific journal of cancer prevention : APJCP (2016)
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Published in Asian Pacific journal of cancer prevention : APJCP (2016)
Journal Article
Role of serum microRNAs 200a, 200b and 200c as biomarkers in Epithelial Ovarian Cancer
Zuberi, Mariyam, Gandhi, Gauri, Saxena, Alpana
Published in Indian journal of clinical biochemistry (24.05.2022)
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Published in Indian journal of clinical biochemistry (24.05.2022)
Journal Article
Inhibition of RAS-driven signaling and tumorigenesis with a pan-RAS monobody targeting the Switch I/II pocket
Wallon, Lauren, Khan, Imran, Teng, Kai Wen, Koide, Akiko, Zuberi, Mariyam, Li, Jianping, Ketavarapu, Gayatri, Traaseth, Nathaniel J, O'Bryan, John P, Koide, Shohei
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2022)
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Journal Article
Abstract PO-032: Targeting the KRAS dimerization interface enhances T-cell mediated anti-tumor response in vivo
Khan, Imran, Lefler, Julia, Marelia, Catherine, Zuberi, Mariyam, Denbaum, Eric, Koide, Akiko, Timmers, Cynthia, Ostrowski, Michael, Koide, Shohei, O’Bryan, John
Published in Cancer research (Chicago, Ill.) (15.11.2020)
Published in Cancer research (Chicago, Ill.) (15.11.2020)
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Journal Article
Abstract 831: Hypermethylation in promoter regions of CpG islands of multiple genes is associated with disease progression and molecular response in chronic myelogenous leukemia
Sumi, Mamta P., Guru, Sameer A., Najar, Imtiyaz A, Zuberi, Mariyam, Gupta, N., Saxena, Alpana
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Exploring switch II pocket conformation of KRAS(G12D) with mutant-selective monobody inhibitors
Akkapeddi, Padma, Hattori, Takamitsu, Khan, Imran, Glasser, Eliezra, Koide, Akiko, Ketavarapu, Gayatri, Whaby, Michael, Zuberi, Mariyam, Teng, Kai Wen, Lefler, Julia, Maso, Lorenzo, Bang, Injin, Ostrowski, Michael C, O'Bryan, John P, Koide, Shohei
Published in Proceedings of the National Academy of Sciences - PNAS (11.07.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (11.07.2023)
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Journal Article
Escalated activation ofSTAT3 due to JAK2 V617F activatingmutation causesdownregulation ofPTEN via miRNA 21overexpression
Sumi, Mamta P., Guru, Sameer A., Mir, Rashid, Najar, Imtiyaz, Zuberi, Mariyam, Gupta, Naresh K., Lali, Pramod, Saxena, Alpana
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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Journal Article
MO3-1-1JAK2 (V617F) positively regulates PD-L1 mRNA expression via STAT3/5 activation in MNP (PV and ET) patients
Guru, Sameer Ahmad, Alpana, Mamta P, Mir, Rashid, Najar, Imtiyaz A, Zuberi, Mariyam, Gupta, Naresh, Lali, Pramod, Saxena, Alpana
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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Journal Article
MO3-1-2Escalated activation ofSTAT3 due to JAK2 V617F activatingmutation causesdownregulation ofPTEN via miRNA 21overexpression
Sumi, Mamta P, Guru, Sameer A, Mir, Rashid, Najar, Imtiyaz, Zuberi, Mariyam, Gupta, Naresh K, Lali, Pramod, Saxena, Alpana
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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Journal Article
JAK2 (V617F) positively regulates PD-L1 mRNA expression via STAT3/5 activation in MNP (PV and ET) patients
Guru, Sameer Ahmad, Alpana, Mamta P., Mir, Rashid, Najar, Imtiyaz A., Zuberi, Mariyam, Gupta, Naresh, Lali, Pramod, Saxena, Alpana
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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Journal Article
Abstract PO-064: Inhibition of RAS signaling and tumorigenesis through novel targeting novel vulnerabilities
Khan, Imran, Koide, Akiko, Zuberi, Mariyam, Denbaum, Eric, Ketavar, Gayatari, Teng, Kai-Wen, Rhett, Matthew, Sepncer-Smith, Russell, Camp, Ernest R., Koide, Shohei, O’Bryan, John
Published in Cancer research (Chicago, Ill.) (15.11.2020)
Published in Cancer research (Chicago, Ill.) (15.11.2020)
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Journal Article