Understanding LAG-3 Signaling
Chocarro, Luisa, Blanco, Ester, Zuazo, Miren, Arasanz, Hugo, Bocanegra, Ana, Fernández-Rubio, Leticia, Morente, Pilar, Fernández-Hinojal, Gonzalo, Echaide, Miriam, Garnica, Maider, Ramos, Pablo, Vera, Ruth, Kochan, Grazyna, Escors, David
Published in International journal of molecular sciences (17.05.2021)
Published in International journal of molecular sciences (17.05.2021)
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Journal Article
PDL1 Signals through Conserved Sequence Motifs to Overcome Interferon-Mediated Cytotoxicity
Gato-Cañas, Maria, Zuazo, Miren, Arasanz, Hugo, Ibañez-Vea, Maria, Lorenzo, Laura, Fernandez-Hinojal, Gonzalo, Vera, Ruth, Smerdou, Cristian, Martisova, Eva, Arozarena, Imanol, Wellbrock, Claudia, Llopiz, Diana, Ruiz, Marta, Sarobe, Pablo, Breckpot, Karine, Kochan, Grazyna, Escors, David
Published in Cell reports (Cambridge) (22.08.2017)
Published in Cell reports (Cambridge) (22.08.2017)
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Journal Article
Functional systemic CD4 immunity is required for clinical responses to PD‐L1/PD‐1 blockade therapy
Zuazo, Miren, Arasanz, Hugo, Fernández‐Hinojal, Gonzalo, García‐Granda, Maria Jesus, Gato, María, Bocanegra, Ana, Martínez, Maite, Hernández, Berta, Teijeira, Lucía, Morilla, Idoia, Lecumberri, Maria Jose, Fernández de Lascoiti, Angela, Vera, Ruth, Kochan, Grazyna, Escors, David
Published in EMBO molecular medicine (01.07.2019)
Published in EMBO molecular medicine (01.07.2019)
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Journal Article
The intracellular signalosome of PD-L1 in cancer cells
Escors, David, Gato-Cañas, María, Zuazo, Miren, Arasanz, Hugo, García-Granda, María Jesus, Vera, Ruth, Kochan, Grazyna
Published in Signal transduction and targeted therapy (28.09.2018)
Published in Signal transduction and targeted therapy (28.09.2018)
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Journal Article
Systemic CD4 Immunity as a Key Contributor to PD-L1/PD-1 Blockade Immunotherapy Efficacy
Zuazo, Miren, Arasanz, Hugo, Bocanegra, Ana, Fernandez, Gonzalo, Chocarro, Luisa, Vera, Ruth, Kochan, Grazyna, Escors, David
Published in Frontiers in immunology (30.11.2020)
Published in Frontiers in immunology (30.11.2020)
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Journal Article
Resistance to PD-L1/PD-1 Blockade Immunotherapy. A Tumor-Intrinsic or Tumor-Extrinsic Phenomenon?
Chocarro de Erauso, Luisa, Zuazo, Miren, Arasanz, Hugo, Bocanegra, Ana, Hernandez, Carlos, Fernandez, Gonzalo, Garcia-Granda, Maria Jesus, Blanco, Ester, Vera, Ruth, Kochan, Grazyna, Escors, David
Published in Frontiers in pharmacology (07.04.2020)
Published in Frontiers in pharmacology (07.04.2020)
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Journal Article
Systemic CD4 immunity: A powerful clinical biomarker for PD‐L1/PD‐1 immunotherapy
Zuazo, Miren, Arasanz, Hugo, Bocanegra, Ana, Chocarro, Luisa, Vera, Ruth, Escors, David, Kagamu, Hiroshi, Kochan, Grazyna
Published in EMBO molecular medicine (07.09.2020)
Published in EMBO molecular medicine (07.09.2020)
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Journal Article
Systemic Blood Immune Cell Populations as Biomarkers for the Outcome of Immune Checkpoint Inhibitor Therapies
Hernandez, Carlos, Arasanz, Hugo, Chocarro, Luisa, Bocanegra, Ana, Zuazo, Miren, Fernandez-Hinojal, Gonzalo, Blanco, Ester, Vera, Ruth, Escors, David, Kochan, Grazyna
Published in International journal of molecular sciences (31.03.2020)
Published in International journal of molecular sciences (31.03.2020)
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Journal Article
PD-L1 in Systemic Immunity: Unraveling Its Contribution to PD-1/PD-L1 Blockade Immunotherapy
Bocanegra, Ana, Blanco, Ester, Fernandez-Hinojal, Gonzalo, Arasanz, Hugo, Chocarro, Luisa, Zuazo, Miren, Morente, Pilar, Vera, Ruth, Escors, David, Kochan, Grazyna
Published in International journal of molecular sciences (18.08.2020)
Published in International journal of molecular sciences (18.08.2020)
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Journal Article
The multi-specific VH-based Humabody CB213 co-targets PD1 and LAG3 on T cells to promote anti-tumour activity
Edwards, Carolyn J., Sette, Angelica, Cox, Carl, Di Fiore, Barbara, Wyre, Chris, Sydoruk, Daniela, Yadin, David, Hayes, Philip, Stelter, Szymon, Bartlett, Phillip D., Zuazo, Miren, Garcia-Granda, Maria Jesus, Benedetti, Giovanni, Fiaska, Stratoniki, Birkett, Neil R., Teng, Yumin, Enever, Carrie, Arasanz, Hugo, Bocanegra, Ana, Chocarro, Luisa, Fernandez, Gonzalo, Vera, Ruth, Archer, Bethan, Osuch, Isabelle, Lewandowska, Martyna, Surani, Yasmin M., Kochan, Grazyna, Escors, David, Legg, James, Pierce, Andrew J.
Published in British journal of cancer (03.05.2022)
Published in British journal of cancer (03.05.2022)
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Journal Article
Hyperprogressive Disease: Main Features and Key Controversies
Arasanz, Hugo, Zuazo, Miren, Bocanegra, Ana, Chocarro, Luisa, Blanco, Ester, Martínez, Maite, Morilla, Idoia, Fernández, Gonzalo, Teijeira, Lucía, Morente, Pilar, Echaide, Miriam, Castro, Natalia, Fernández, Leticia, Garnica, Maider, Ramos, Pablo, Escors, David, Kochan, Grazyna, Vera, Ruth
Published in International journal of molecular sciences (03.04.2021)
Published in International journal of molecular sciences (03.04.2021)
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Journal Article
PD-1/LAG-3 co-signaling profiling uncovers CBL ubiquitin ligases as key immunotherapy targets
Chocarro, Luisa, Blanco, Ester, Fernandez-Rubio, Leticia, Garnica, Maider, Zuazo, Miren, Garcia, Maria Jesus, Bocanegra, Ana, Echaide, Miriam, Johnston, Colette, Edwards, Carolyn J, Legg, James, Pierce, Andrew J, Arasanz, Hugo, Fernandez-Hinojal, Gonzalo, Vera, Ruth, Ausin, Karina, Santamaria, Enrique, Fernandez-Irigoyen, Joaquin, Kochan, Grazyna, Escors, David
Published in EMBO molecular medicine (12.08.2024)
Published in EMBO molecular medicine (12.08.2024)
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Journal Article
Establishment and Characterization of a Stable Producer Cell Line Generation Platform for the Manufacturing of Clinical-Grade Lentiviral Vectors
Arrasate, Ane, Bravo, Igone, Lopez-Robles, Carlos, Arbelaiz-Sarasola, Ane, Ugalde, Maddi, Meijueiro, Martha Lucia, Zuazo, Miren, Valero, Ana, Banos-Mateos, Soledad, Ramirez, Juan Carlos, Albo, Carmen, Lamsfus-Calle, Andrés, Fertin, Marie J
Published in Biomedicines (04.10.2024)
Published in Biomedicines (04.10.2024)
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Journal Article
PD-L1 Expression in Systemic Immune Cell Populations as a Potential Predictive Biomarker of Responses to PD-L1/PD-1 Blockade Therapy in Lung Cancer
Bocanegra, Ana, Fernandez-Hinojal, Gonzalo, Zuazo-Ibarra, Miren, Arasanz, Hugo, Garcia-Granda, Maria Jesus, Hernandez, Carlos, Ibañez, Maria, Hernandez-Marin, Berta, Martinez-Aguillo, Maite, Lecumberri, Maria Jose, Fernandez de Lascoiti, Angela, Teijeira, Lucia, Morilla, Idoia, Vera, Ruth, Escors, David, Kochan, Grazyna
Published in International journal of molecular sciences (02.04.2019)
Published in International journal of molecular sciences (02.04.2019)
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Journal Article
Myeloid-Derived Suppressor Cells in the Tumor Microenvironment: Current Knowledge and Future Perspectives
Ibáñez-Vea, Maria, Zuazo, Miren, Gato, Maria, Arasanz, Hugo, Fernández-Hinojal, Gonzalo, Escors, David, Kochan, Grazyna
Published in Archivum Immunologiae et Therapiae Experimentalis (01.04.2018)
Published in Archivum Immunologiae et Therapiae Experimentalis (01.04.2018)
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Journal Article
TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy
De Ridder, Kirsten, Locy, Hanne, Piccioni, Elisa, Zuazo, Miren Ibarra, Awad, Robin Maximilian, Verhulst, Stefaan, Van Bulck, Mathias, De Vlaeminck, Yannick, Lecocq, Quentin, Reijmen, Eva, De Mey, Wout, De Beck, Lien, Ertveldt, Thomas, Pintelon, Isabel, Timmermans, Jean-Pierre, Escors, David, Keyaerts, Marleen, Breckpot, Karine, Goyvaerts, Cleo
Published in Frontiers in immunology (14.04.2022)
Published in Frontiers in immunology (14.04.2022)
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Journal Article
Immunotherapy in malignant melanoma: recent approaches and new perspectives
Arasanz, Hugo, Lacalle, Alejandra, Lecumberri, Maria José, de Lascoiti, Ángela Fernández, Blanco-Luquin, Idoia, GatoCañas, María, Pérez-Ricarte, Leyre, Zuazo, Miren, Kochan, Grazyna, Escors, David
Published in Melanoma management (01.03.2017)
Published in Melanoma management (01.03.2017)
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Journal Article
PD1 signal transduction pathways in T cells
Arasanz, Hugo, Gato-Cañas, Maria, Zuazo, Miren, Ibañez-Vea, Maria, Breckpot, Karine, Kochan, Grazyna, Escors, David
Published in Oncotarget (01.08.2017)
Published in Oncotarget (01.08.2017)
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Journal Article
Functional systemic CD4 immunity is required for clinical responses to PD-L1/PD-1 blockade therapy
Zuazo, Miren, Arasanz, Hugo, Fernández-Hinojal, Gonzalo, García-Granda, Maria Jesus, Gato, María, Bocanegra, Ana, Martínez, Maite, Hernández, Berta, Teijeira, Lucía, Morilla, Idoia, Lecumberri, Maria Jose, Fernández de Lascoiti, Angela, Vera, Ruth, Kochan, Grazyna, Escors, David
Published in EMBO molecular medicine (01.07.2019)
Published in EMBO molecular medicine (01.07.2019)
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Journal Article
Early Detection of Hyperprogressive Disease in Non-Small Cell Lung Cancer by Monitoring of Systemic T Cell Dynamics
Arasanz, Hugo, Zuazo, Miren, Bocanegra, Ana, Gato, María, Martínez-Aguillo, Maite, Morilla, Idoia, Fernández, Gonzalo, Hernández, Berta, López, Paúl, Alberdi, Nerea, Hernández, Carlos, Chocarro, Luisa, Teijeira, Lucía, Vera, Ruth, Kochan, Grazyna, Escors, David
Published in Cancers (04.02.2020)
Published in Cancers (04.02.2020)
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Journal Article